Signs and symptoms Patients often present with the classic triad of left lower quadrant pain, fever, and leukocytosis (an elevation of the white cell count in blood tests). Patients may also complain of nausea or diarrhea; others may be constipated. [sites.google.com]

Though a physical exam may be unremarkable, it most likely will reveal left-lower quadrant pain, abdominal tenderness and potentially an abdominal mass. Fever and leukocytosis may also be present, but those findings are non-specific [ 30 ]. [mdpi.com]

It cites the case of a 28-year-old, with clinical symptoms of headache 1 month of evolution with neuroimaging findings transverse sinus thrombosis and left sigmoid with protein S deficiency. [glosbe.com]