Presentation
The findings indicate that increased TSAb and TBII activity may be detected in patients with silent thyroiditis and, when present, are associated with transient hypothyroidism during the course of the disease. [ncbi.nlm.nih.gov]
Presented at: 2017 AACE Annual Scientific & Clinical Congress, May 3-7, in Austin, Texas. [psychiatryadvisor.com]
Luke’s Hospital in Chesterfield, Missouri, presented the case of an 18-year-old woman with bipolar disorder. [endocrinologyadvisor.com]
Antimicrosomal antibodies are present in 50 to 80 percent of patients, while antithyroid peroxidase antibodies are present in nearly all patients. 3, 6, 7 Subacute lymphocytic thyroiditis starts with an initial hyperthyroid phase, followed by subsequent [aafp.org]
Entire Body System
- Fatigue
Weight loss Later symptoms may be of an underactive thyroid ( hypothyroidism ), including fatigue and cold intolerance, until the thyroid recovers. [nlm.nih.gov]
After a period of time, did your symptoms dissipate and leave you with fatigue and muscle weakness? This symptom pattern tends to indicate lymphocytic thyroiditis, also called silent thyroiditis. [healthblurbs.com]
Symptoms associated with thyrotoxic phase include: Insomnia Anxiety weight loss palpitations irritability Fatigue Symptoms associated with hypothyroid phase include: weight gain constipation fatigue depression dry skin poor exercise tolerance Painless [hyperthyroidismsymptomsx.com]
Sixteen weeks after initiation of the treatment, she complained of increasing fatigue, palpitation and losing 7 kg in weight. [ncbi.nlm.nih.gov]
- Weight Loss
Symptoms associated with thyrotoxic phase include: Insomnia Anxiety weight loss palpitations irritability Fatigue Symptoms associated with hypothyroid phase include: weight gain constipation fatigue depression dry skin poor exercise tolerance Painless [hyperthyroidismsymptomsx.com]
loss Later symptoms may be of an underactive thyroid ( hypothyroidism ), including fatigue and cold intolerance, until the thyroid recovers. [nlm.nih.gov]
After several months, the patient presented with symptoms of hyperthyroidism, including jitteriness, irregular menstruation, hair loss, diarrhea, and a 10-lb weight loss. [psychiatryadvisor.com]
[…] thinking Fatigue and tiredness Dry skin Hair loss, which may be in excess while showering Constipation or difficult bowel movements Weight gain that may be slow and gradual Heavy and irregular periods (in women) Abnormal sensitivity to cold; the affected [dovemed.com]
- Weakness
Early in her admission she was dehydrated and had febrile episodes, paroxysmal atrial fibrillation, and muscle weakness. [ncbi.nlm.nih.gov]
A 23-year-old gentleman was admitted with acute onset weakness of both upper and lower limbs after rising from bed. Weakness was more in lower limbs and proximally. [annalsofian.org]
After a period of time, did your symptoms dissipate and leave you with fatigue and muscle weakness? This symptom pattern tends to indicate lymphocytic thyroiditis, also called silent thyroiditis. [healthblurbs.com]
Symptoms are often mild, and may include: Fatigue, feeling weak Frequent bowel movements Heat intolerance Increased appetite Increased sweating Irregular menstrual periods Mood changes, such as irritability Muscle cramps Nervousness, restlessness Palpitations [nlm.nih.gov]
- Heat Intolerance
A month after rubella infection, she developed heat intolerance. Physical examination revealed a hard and non-tender goiter with no signs or symptoms of inflammation. [ncbi.nlm.nih.gov]
Symptoms are often mild, and may include: Fatigue, feeling weak Frequent bowel movements Heat intolerance Increased appetite Increased sweating Irregular menstrual periods Mood changes, such as irritability Muscle cramps Nervousness, restlessness Palpitations [nlm.nih.gov]
A month after rubella infection, she developed heat intolerance(21). 7. Gender If you are women, you are associated to increased risk of silent thyroiditis 8. [beforeitsnews.com]
intolerance Anxiety and nervousness Increased appetite Tremors Hypothyroid phase (more common) : Can be long-lasting and may become permanent. [my.clevelandclinic.org]
- Cold Intolerance
Weight loss Later symptoms may be of an underactive thyroid ( hypothyroidism ), including fatigue and cold intolerance, until the thyroid recovers. [nlm.nih.gov]
These symptoms may last for a couple of months and then be followed by symptoms an underactive thyroid, including: fatigue myalgia arthralgia weight gain dry skin, hair muscle spasms cold intolerance muscle weakness For many, their silent thyroiditis [healthblurbs.com]
Tremor Sweating Weight loss Symptoms associated with hypothyroidism include: Constipation Fatigue Cold intolerance Function of thyroid gland returns to normal and rarely few cases develop permanent hypothyroidism. [hyperthyroidismsymptomsx.com]
Symptoms of Hashimoto's thyroiditis may include fatigue, depression, cold intolerance, weight gain, dry skin and hair, muscle cramps, constipation, decreased concentration and sleepiness, leg swelling, puffy eyes; severe symptoms include a slow heart [rxlist.com]
Respiratoric
- Hoarseness
Patients with acute thyroiditis present with acute illness, including neck pain,painless enlargement of the thyroid,fever (38-40°C), sore throat, chills, hoarseness, hypothyroidism and dysphagia. [hyperthyroidismsymptomsx.com]
With this, you can also have hypoparathyroidism, hoarseness from problems to your larynx, and a compression of your tracheal tube. Your thyroid will feel quite hard. [stopthethyroidmadness.com]
Early nonspecific symptoms may include the following: Fatigue Constipation Dry skin Weight gain More advanced/florid symptoms may include the following: Cold intolerance Voice hoarseness and pressure symptoms in the neck from thyroid enlargement Slowed [emedicine.medscape.com]
Weakness, tiredness, hoarseness, hair loss, intolerance to cold, constipation, sleep disturbance. Goitre, delayed relaxation of deep tendon reflexes. Anaemia, low T4, raised TSH. In the subclinical form TSH is raised but free T4 and T3 are normal. [patient.info]
Gastrointestinal
- Constipation
The symptoms of hypothyroidism (under active thyroid) include: Constipation Fatigue Depression Abrupt weight gain Muscle aches Dry skin Thyroiditis also results in leakage of thyroid hormone from the gland by damaging and destroying the thyroid cells, [hyperthyroidismsymptomsx.com]
Typical hypothyroid symptoms include fatigue, weight gain, constipation, dry skin, depression and poor exercise tolerance. This would be the case in patients with Hashimoto’s thyroiditis. [thyroid.org]
Symptoms of Hashimoto's thyroiditis may include fatigue, depression, cold intolerance, weight gain, dry skin and hair, muscle cramps, constipation, decreased concentration and sleepiness, leg swelling, puffy eyes; severe symptoms include a slow heart [rxlist.com]
If cells are damaged and thyroid hormone levels fall, you might show symptoms of hypothyroidism, such as: Fatigue Unexpected weight gain Constipation Depression Dry skin Difficulty performing physical exercise Decreased mental ability to concentrate and [my.clevelandclinic.org]
- Diarrhea
The patient was a 64-year-old woman who was admitted for muscle weakness in the lower extremities, diarrhea, and palpitations. She had bipolar disorder and was being treated with lithium carbonate, which she discontinued one week before admission. [ncbi.nlm.nih.gov]
After several months, the patient presented with symptoms of hyperthyroidism, including jitteriness, irregular menstruation, hair loss, diarrhea, and a 10-lb weight loss. [psychiatryadvisor.com]
Two weeks before the first admission, he consulted his physician because of palpitation and diarrhea. His clinical manifestations and thyroid function indicated profound thyrotoxicosis. [karger.com]
Other symptoms include: Fatigue Dysphagia (swallowing difficulty) Hoarseness Fever Weakness Tenderness of the thyroid gland on releasing gentle pressure Symptoms associated with hyperthyroidism include: Heat intolerance Diarrhea Palpitations Nervousness [hyperthyroidismsymptomsx.com]
- Increased Appetite
Symptoms are often mild, and may include: Fatigue, feeling weak Frequent bowel movements Heat intolerance Increased appetite Increased sweating Irregular menstrual periods Mood changes, such as irritability Muscle cramps Nervousness, restlessness Palpitations [nlm.nih.gov]
The most commonly experienced symptoms of this disorder include: Insomnia or difficulty falling asleep Tiredness and weakness Frequent bowel movements Intolerance towards heat and excessive sweating Increased appetite Weight loss Irregular menstruation [lybrate.com]
[…] intolerance Anxiety and nervousness Increased appetite Tremors Hypothyroid phase (more common) : Can be long-lasting and may become permanent. [my.clevelandclinic.org]
Among the symptoms may be found: Intolerance to heat Tiredness, fatigue, and difficulty concentrating Increased appetite Weight loss Frequent bowel movements and diarrhea Restlessness, anxiety, and nervousness Increased sweating Goiter (visibly inflamed [steptohealth.com]
- Vomiting
You may need treatment with an intravenous (IV) antibiotic if your doctor is concerned that your infection is progressing rapidly, if you can't swallow oral medication, or if you are vomiting so much that you can't absorb oral medication. [verywell.com]
Heavy exercise, carbohydrate load, vomiting, and diarrhea did not precipitate the weakness. No family member had similar symptoms. [annalsofian.org]
- Abdominal Pain
Your physician should be contacted if there is yellowing of the skin jaundice, fever, loss of appetite or abdominal pain. Radioactive Iodine Treatment Iodine is an essential ingredient in the production of thyroid hormone. [thyroidawareness.com]
Cardiovascular
- Tachycardia
This health condition can result in variety of symptoms, such as: tremors heat sensitivity sleep difficulties appetite increase excessive sweating irregular menstrual cycle sudden, inexplicable weight loss nervousness, anxiety & irritability tachycardia [healthblurbs.com]
These symptoms include : weight loss, irritability, anxiety, insomnia, tachycardia fatigue. 6 Elevated levels of thyroid hormone in the bloodstream cause both conditions. [slideplayer.com]
His physical findings on admission included low-grade fever (37-38°C), tachycardia (140-160 beats/min) with irregular rhythm, finger tremor, and excessive sweating. He suffered from severe diarrhea 3 weeks before the second admission. [karger.com]
[…] comorbidities Prognosis patients will generally return to normal thyroid function within a year Presentation Symptoms anterior neck and jaw pain de Quer vain causes pain flu-like prodrome fever, malaise, and fatigue 3 phases hyperthyroid phase nervousness, tachycardia [medbullets.com]
Vitals - bradycardia with hypotension or tachycardia with hypertension? 5. Weight - increase or decrease? 6. body temp - low? 7. Facial appearance - loss of hair? puffiness? 8. Eyes - exopthalmos? lid lag? 9. Hair growth patterns 10. [brainscape.com]
Musculoskeletal
- Muscle Cramp
Symptoms are often mild, and may include: Fatigue, feeling weak Frequent bowel movements Heat intolerance Increased appetite Increased sweating Irregular menstrual periods Mood changes, such as irritability Muscle cramps Nervousness, restlessness Palpitations [nlm.nih.gov]
cramps Irritability Nervousness and palpitations Hair loss and dry skin Silent Thyroiditis can be diagnosed by a doctor through a physical examination and a few tests. [lybrate.com]
Symptoms of Hashimoto's thyroiditis may include fatigue, depression, cold intolerance, weight gain, dry skin and hair, muscle cramps, constipation, decreased concentration and sleepiness, leg swelling, puffy eyes; severe symptoms include a slow heart [rxlist.com]
Skin
- Sweating
Medicines called beta-blockers may be used to relieve rapid heart rate and excessive sweating. Silent thyroiditis often goes away on its own within 1 year. The acute phase ends within 3 months. Some people develop hypothyroidism over time. [nlm.nih.gov]
Generally, treatment involves taking beta blockers to relieve symptoms of rapid heart rate and excessive sweating during excess hormone phase. [healthblurbs.com]
Beta blockers are commonly prescribed to relieve the excessive sweating and rapid heartbeat. In most cases, the acute phase of this disorder will end in three months and the condition will resolve itself within a year. [lybrate.com]
The associated signs and symptoms of hyperthyroidism may include: Sleeping difficulties including insomnia Excess sweating and intolerance to heat Increased to excessive hunger Irritation, restlessness, and nervousness Protrusion of the eyes Menstrual [dovemed.com]
- Increased Sweating
Symptoms are often mild, and may include: Fatigue, feeling weak Frequent bowel movements Heat intolerance Increased appetite Increased sweating Irregular menstrual periods Mood changes, such as irritability Muscle cramps Nervousness, restlessness Palpitations [nlm.nih.gov]
If cells are damaged quickly and there is a leak of excess thyroid hormone, you might show symptoms of hyperthyroidism, such as: Being worried Feeling irritable Trouble sleeping Fast heart rate Fatigue Unplanned weight loss Increased sweating and heat [my.clevelandclinic.org]
[…] functioning of thyroid gland) followed by hypothyroidism (decreased functioning of the gland), before coming to a state of normally functioning thyroid The common signs and symptoms of Postpartum Silent Thyroiditis include weight loss, increased sweating [dovemed.com]
- Brittle Hair
Pervasive fatigue Drowsiness Forgetfulness Difficulty with learning Dry, brittle hair and nails Dry, itchy skin Puffy face Constipation Sore muscles Weight gain and fluid retention Heavy and/or irregular menstrual flow Increased frequency of miscarriages [thyroidawareness.com]
Psychiatrical
- Hunger
The associated signs and symptoms of hyperthyroidism may include: Sleeping difficulties including insomnia Excess sweating and intolerance to heat Increased to excessive hunger Irritation, restlessness, and nervousness Protrusion of the eyes Menstrual [dovemed.com]
Urogenital
- Irregular Menstruation
After several months, the patient presented with symptoms of hyperthyroidism, including jitteriness, irregular menstruation, hair loss, diarrhea, and a 10-lb weight loss. [psychiatryadvisor.com]
The most commonly experienced symptoms of this disorder include: Insomnia or difficulty falling asleep Tiredness and weakness Frequent bowel movements Intolerance towards heat and excessive sweating Increased appetite Weight loss Irregular menstruation [lybrate.com]
Neurologic
- Irritability
Symptoms are often mild, and may include: Fatigue, feeling weak Frequent bowel movements Heat intolerance Increased appetite Increased sweating Irregular menstrual periods Mood changes, such as irritability Muscle cramps Nervousness, restlessness Palpitations [nlm.nih.gov]
The associated signs and symptoms of hyperthyroidism may include: Sleeping difficulties including insomnia Excess sweating and intolerance to heat Increased to excessive hunger Irritation, restlessness, and nervousness Protrusion of the eyes Menstrual [dovemed.com]
[…] difficulty falling asleep Tiredness and weakness Frequent bowel movements Intolerance towards heat and excessive sweating Increased appetite Weight loss Irregular menstruation : this may be short in the early stages and heavy in later stages Muscle cramps Irritability [lybrate.com]
- Hyperactivity
In its early stages, the symptoms of this disorder are those of a hyperactive thyroid gland. These symptoms can last for as long as 3 months. In most cases, these symptoms are mild. [lybrate.com]
[…] normal thyroid function within a year Presentation Symptoms anterior neck and jaw pain de Quer vain causes pain flu-like prodrome fever, malaise, and fatigue 3 phases hyperthyroid phase nervousness, tachycardia, and palpitations sweating resting tremor hyperactive [medbullets.com]
(Etiology) The exact cause of Postpartum Silent Thyroiditis is unknown It is believed to develop due to an immune attack against the thyroid gland due to hyperactivity of the individual’s own immune system; it is an autoimmune disorder What are the Signs [dovemed.com]
Its antioxidant content might help improve your thyroid hyperactivity. Postpartum thydroiditis Following pregnancy in some women, some antibodies may remain in the body that attack the thyroid. [steptohealth.com]
- Agitation
In the first phase thyroid hormone levels will rise and this is likely to result in the symptoms of hyperthyroidism such as palpitations and agitation. [markvanderpump.co.uk]
No psychomotor agitation, mood swing, or disruption of thought was observed. A physical examination showed that her blood pressure was 130/90 mmHg and that her small goiter was palpable. [jmedicalcasereports.biomedcentral.com]
- Somnolence
[…] and loss of energy Decreased sweating Mild nerve deafness Peripheral neuropathy Galactorrhea Depression, dementia, and other psychiatric disturbances Memory loss Joint pains and muscle cramps Hair loss Menstrual irregularities Sleep apnea and daytime somnolence [emedicine.medscape.com]
- Vertigo
The next morning when I woke up I knew something was seriously wrong, my heart was pounding out my chest, sweating profusely, I couldn't think, I had severe vertigo and basically felt as though I had a terrible virus of some sort. [medhelp.org]
Workup
Hashimoto thyroiditis is part of the spectrum of autoimmune thyroid diseases (AITDs). [24] (See Etiology, Presentation, and Workup.) [emedicine.medscape.com]
Although she denied our advice to admit herself, she underwent a thorough medical workup. Our patient's medical history was significant for diagnoses of Hashimoto's thyroiditis, hypertension and hyperlipidemia at the age of 48. [jmedicalcasereports.biomedcentral.com]
Other Pathologies
- Lymphocytic Infiltrate
In both silent and chronic thyroiditis, a great majority of lymphocytes infiltrating between thyroid follicles showed a T-cell phenotype, and no significant differences in T-cell and B-cell distribution between the diseases were observed. [ncbi.nlm.nih.gov]
There is a suggestion that silent thyroiditis is an autoimmune disease characterized by lymphocytic infiltration of the thyroid and by transient hyperthyroidism, followed occasionally by transient hypothyroidism and eventual recovery(12). [beforeitsnews.com]
Histologically, the gland is characterized lymphocytic infiltration, occasionally to the point of lymphoid follicle formation. [radiopaedia.org]
Thyroid biopsy reveals lymphocytic infiltration as in Hashimoto thyroiditis but without lymphoid follicles and scarring. [msdmanuals.com]
Surrounding lymphoid follicular formation; lymphocyte infiltration was evident in the follicular epithelium ( b ). [karger.com]
Treatment
A 28-year-old woman with thyroid hemiagenesis, who had been diagnosed as having Graves' disease, became pregnant during the course of methimazole treatment. The treatment was terminated in the second trimester. [ncbi.nlm.nih.gov]
Hyperthyroidism Treatment Thyroid hormone production can be slowed or stopped completely with: Radioactive iodide treatment Anti-thyroid medication Surgery Continued If your doctor decides that radioactive treatment is best, you'll swallow a tablet or [webmd.com]
Prognosis
Long-term prognosis is usually excellent. [ncbi.nlm.nih.gov]
Treatment and prognosis The course is usually benign and transient. Moderate doses of β-adrenergic blocking agents may provide symptomatic relief. Promoted articles (advertising) [radiopaedia.org]
Untreated myxedema coma has a poor prognosis and a high mortality rate. [emedicine.medscape.com]
Etiology
Its etiology is uncertain; however, a few reports have indicated the occurrence of TSH binding-inhibiting immunoglobulins (TBII) and thyroid-stimulating antibodies (TSAb) in some of the patients. [ncbi.nlm.nih.gov]
[…] which produce antithyroid antibodies) AUTOIMMUNE THYROIDITIS ETIOLOGY 44. [slideshare.net]
International specialists in Microbiology, Infectious Diseases, Internal Medicine, Cardiology Immunology, Pneumonolgy, Neurology and Epidemiology gathered to this workshop to discuss and enhance interdisciplinary knowledge on the possible etiological [books.google.de]
Cases of lesser severity also exist, and the etiology may be confusing. [prep4usmle.com]
Disease course Although the etiology appears to be different for the three subtypes, the clinical courses are the same. [emedicine.medscape.com]
Epidemiology
Current deficits and goals in standardisation of diagnostic tools, basic and applied research, design of epidemiological and monitoring of therapy studies were identified. [books.google.de]
Introduction Clinical definition a granulomatous autoimmune disease of the thyroid that causes hyperthyroidism that may be followed by a hypothyroid phase also known as de Quervain or granulomatous thyroiditis Epidemiology demographics women > men adults [medbullets.com]
EPIDEMIOLOGY Women are three to five times more likely to be affected than men. [aafp.org]
Hypothyroidism Epidemiology Hypothyroidism (including subclinical hypothyroidism) occurs in 2.5% of pregnant women. [patient.info]
Pathophysiology
Pathophysiology Destruction of follicular epithelium and loss of follicular integrity are the primary events in the pathophysiology of subacute granulomatous thyroiditis. [emedicine.medscape.com]
Prevention
Rapidly find the answers you need with separate sections on diseases and disorders, differential diagnosis, clinical algorithms, laboratory results, and clinical preventive services, plus an at-a-glance format that uses cross-references, outlines, bullets [books.google.de]
One patient was unsuccessfully prescribed thyroid hormone to prevent recurrence. Three were treated with radioablative iodine therapy during the recovery phase of an episode; they became hypothyroid and take replacement l-thyroxine. [ncbi.nlm.nih.gov]
Prevention Flu shots or immunizations for measles, mumps, and rubella may help prevent conditions associated with subacute thyroiditis. There is no known way to prevent other forms of thyroiditis. [encyclopedia.com]
The exact cause of Postpartum Silent Thyroiditis is not known, and hence currently, there is no known preventive method reported for the condition Screening of thyroid function during and after pregnancy can avoid the development of severe signs and symptoms [dovemed.com]