Here we present an unusual clinical presentation of a silicone granuloma in a patient with a 27-year history of a wide excision of a melanoma of the right lower extremity and subsequent soft-tissue reconstruction using a silicone device. [ncbi.nlm.nih.gov]

Patients who present with a history of silicone injection to the buttocks or gluteal region may present with debilitating complications, such as chronic pain, chronic infections such as cellulitis and abscesses; skin necrosis and silicone granulomas that [houstonvaserliposuction.com]

• Cervical Lymphadenopathy

  This case highlights the importance for otolaryngologists to consider silicone granuloma among the differential diagnoses of cervical lymphadenopathy in patients with a history of silicone breast implants. [ncbi.nlm.nih.gov]

  The most frequently involved cervical lymph node chain was the transverse cervical, with 7 cases ( Fig. 2 ). In addition, CT studies also detected a significant increase of non-cervical lymphadenopathies in 8 patients, mainly axillary. [elsevier.es]

• Aspiration

  Ultrasonography guided fine needle aspiration was inconclusive and initial review of subsequent computed tomography failed to identify a cause. [ncbi.nlm.nih.gov]

  Fine needle aspiration findings favoured reactive hyperplasia, but a malignant process could not be excluded. [doi.org]

  Fine needle aspiration cytology (FNAC) was conducted for palpable lesions in both breasts and confirmed to be granulomatous reaction secondary to intramammary silicone injection. [casereports.bmj.com]

  Results In a 10-year period, we identified 12 cases with silicone-infiltrated neck lymphadenopathies, histologically confirmed by fine needle aspiration. They represented 3.5% of patients attended for neck lymph node study. [elsevier.es]

• Skin Ulcer

  Skin ulcer: A long-term complication after massive liquid silicone oil infiltration. Aesthetic Plast Surg 2013;37:1220-4. 9. Fumo G, Ferreli F, Murgia S, Galletti R, Pau M. [ijps.org]

• Withdrawn

  CA CA 2741023 patent/CA2741023A1/en not_active Abandoned 2009-10-20 EA EA201100671A patent/EA201100671A1/en unknown 2009-10-20 US US12/998,409 patent/US20110229399A1/en not_active Abandoned 2009-10-20 EP EP20090756564 patent/EP2362852A2/en not_active Withdrawn [google.com]

MRI of the penis by combining both conventional and functional information represents an important imaging tool in the preoperative workup of silicone-induced penile lipogranuloma. [clinicalimagingscience.org]

• Granulomatous Tissue

  Pathology results confirmed granulomatous tissue without malignancy. There were no postoperative complications and the patient was discharged after five days in the hospital. [jcasonline.com]

Pain improved tremendously; however, the induration and subcutaneous nodules remained unchanged (after 1 month of treatment with etanercept). Treatment of silicone granulomas is difficult and often unsuccessful. [jamanetwork.com]

treatments and I have heard used in silicone related illness treatments as well. [gotpummped.wordpress.com]

The refractory silicone granuloma responded dramatically to treatment with etanercept. [ncbi.nlm.nih.gov]

The disease has a relatively higher occurrence among young people, and its prognosis (3-year-survival of only 38%) is extremely poor compared to breast cancer. [ncbi.nlm.nih.gov]

Breast cancer diagnosis and prognosis in augmented women. Plast Reconstr Surg. 2006;118(3):587–93. discussion 594-6. 14. Peng HL, Wu CC, Choi WM, Hui MS, Lu TN, Chen LK. [wjso.biomedcentral.com]

Biana Brovina et bp Maj, 2012 FACTOR AFFECTING THE PROGNOSIS OF ALBANIAN ADULTS PATIENTS WITH GENERALIZED TETANUS. PILACA, A. Beqiri, A.NDREU. Il Giornale di chirurgia ISSN 0391-9005 UDC 61, VOL, 18, Prill 2012. [ual.edu.al]

[…] mammoplasty and joint prostheses ( Hum Pathol 1980;11:240 ) Once released into tissue, silicone migrates to distant sites through lymphatic channels and bloodstream Once it reaches lymph nodes, it elicits a reaction and cause silicone lymphadenopathy Etiology [pathologyoutlines.com]

The extent of lymphocytic cuffing was more extensive than typically observed in sarcoidosis, but pathology alone could not rule out sarcoidosis or an infectious etiology. [avensonline.org]

(poster) THE EPIDEMIONOLOGICAL THE ETIOLOGICAL AND THE CLINICAL APECTS OF THE COMA STATE IN INFECTIOUS DISEASES. Ndreu. The 6 Euroasia Congress of Infectious Diseases 24-27 September 2014. Belgrade, Serbia. [ual.edu.al]

The role of silicone gel in relation to connective tissue disease or amyloidosis has not been proved by current serologic, immunologic, or epidemiologic tests. [doi.org]

EPIDEMIOLOGICAL ASPECTS, CLINICAL AND THERAPEUTIC OF CEREBAL MALARIA CASES IMPORTED IN ALABANIA NDREU, A. Andoni, D.Hajdari, Dh.Kraja,. [ual.edu.al]

Understanding their pathophysiology is essential in differential diagnosis and appropriate management. [aestheticsjournal.com]

[…] enlargement of regional lymph nodes caused by the presence of silicone carried from tributary organs Either an incidental finding or causes painful / enlarged lymph node May be associated with granulomatous inflammation ( Histol Histopathol 1997;12:1003 ) Pathophysiology [pathologyoutlines.com]

"Amyloidosis and silicone synovitis: Updated classification, updated pathophysiology, and synovial articular abnormalities". Radiologic Clinics of North America. 34 (2): 375–94, xi. PMID 8633122. [en.wikipedia.org]

Thick sections (10-30 micrometer thick) prevent loss of silicone droplets during tissue processing. The silicones can be detected by adding stamp pad ink to the mounting medium. [histopathology-india.net]

Counselling the patient and adopting preventative measures such appropriate filler choice and prevention of infection should be part of every case of dermal filler injections. [aestheticsjournal.com]

An interleukin 1 receptor antagonist was started to prevent the extension of amyloidosis, but to no avail as far as the kidneys are concerned. [doi.org]

It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. [gotpummped.wordpress.com]

When comparing with other causes of implant rupture, CSG potentially damaging effect may most likely only play a minor role in implant rupture but is surgically preventable. [pubs.sciepub.com]