Presentation
The first subject presented a multicavitary lesion in the apex of the right lung, which subsequently evolved with fibrosis. [monaldi-archives.org]
This disease has various clinical presentations, among which are the chronic, acute, and accelerated forms. [inis.iaea.org]
[Case Reports] Indian J Occup Environ Med. 2016 Jan-Apr; 20(1):60-3.Rai S, Acharya V, … Chakraborti S IJ We present a case of acute silicosis presenting with severe breathlessness and respiratory failure. [unboundmedicine.com]
Respiratoric
- Dyspnea
Paracelsus1 described the chronic lung trouble of miners as "lung consumption," "asthma" and "dyspnea." [jamanetwork.com]
As the disease progresses, airflow limitation occurs, manifested by dyspnea and cough. Eventually, cor pulmonale and respiratory failure develop. [emedicine.com]
Among symptomatic patients, dyspnea is common but is usually severe only if there is progressive massive fibrosis. [ilo.org]
- Chronic Cough
Workers with Silicosis may have following symptoms: Shortness of breath following physical exertion, severe and chronic cough, fatigue, loss of appetite, chest pains and fevers. [silicosis-injury-attorneys.com]
Case report Section: A 76-year-old woman was initially admitted to the hospital on 9 November 2007 with a 2-week history of acute exacerbation of a chronic cough and dysphagia involving both solids and liquids. [doi.org]
Chronic cough and exertional dyspnea (shortness of breath) are common findings. Radiographically, chronic simple silicosis reveals a profusion of small (<10 mm in diameter) opacities, typically rounded, and predominating in the upper lung zones. [en.wikipedia.org]
The details of the method of recruitment of the patients in the clinic have been explained elsewhere. [6] Inclusion criteria Patients above 15 years of age of both genders living in Shakarpur, having symptoms of chronic cough for more than 3 months and [lungindia.com]
- Sputum Production
In June 2009 (16 months later), the patient was admitted to the hospital for the third time because of a 10-day history of coughing, sputum production, dyspnoea, fever, and night sweats. [doi.org]
- Productive Cough
Other symptoms reported by mine workers were chest pain, dry cough, productive cough, haemoptysis, palpitations, easy fatiguability, evening fever and weight loss. [journals.plos.org]
Cardiovascular
- Cyanosis
In the acute form, patients develop shortness of breath, fever, and cyanosis. In the chronic form patients, develop progressive shortness of breath. 502 Pneumoconiosis due to other silica or silicates convert 502 to ICD-10-CM [icd9data.com]
He was dyspneic without cyanosis, clubbing, or lymphadenopathy. On auscultation; fine crackles in bilateral upper and mid zones at the end of inspiration were present. [annalsafrmed.org]
Silicosis, which can take up to 15 years to develop and includes symptoms like shortness of breath, cough, fever, cyanosis (bluish skin) and frequent chest infections which lead to lung transplants and even death, can be caused by long-term exposure to [news.com.au]
It is a type of pneumoconiosis.Silicosis (particularly the acute form) is characterized by shortness of breath, cough, fever, and cyanosis (bluish skin). [en.wikipedia.org]
Neurologic
- Encephalopathy
Autoantibodies to brain components and antibodies to Acinetobacter calcoaceticus are present in bovine spongiform encephalopathy. Infect. Immun. 67 : 6591-6595. [ PMC free article ] [ PubMed ] [ Google Scholar ] 230. Tobias, H. J., M. P. Schafer, M. [ncbi.nlm.nih.gov]
Workup
X-Ray
- Cavitary Lesion
Axial HRCT scan (C:-600, W: 1600) shows an irregular thick-walled cavitary lesion (arrow) in the upper lobe of right lung, suggestive of pulmonary tuberculosis. [ijri.org]
Pleura
- Pleural Exudate
Occupational history, radiology (conventional chest radiography and computed tomography) and microbiology (identification of Mycobacterium tuberculosis in sputum and pleural exudate) are helpful for the correct diagnosis, which, in turn, is important [monaldi-archives.org]
Treatment
It should be emphasized that surgical treatments more aggressive than have been heretofore practiced can be employed. [ncbi.nlm.nih.gov]
[…] history, radiology (conventional chest radiography and computed tomography) and microbiology (identification of Mycobacterium tuberculosis in sputum and pleural exudate) are helpful for the correct diagnosis, which, in turn, is important for prognosis and treatment [monaldi-archives.org]
New anti-TB drugs are now in clinical evaluation and will soon become available for the treatment of patients. This Monograph focuses on developments in the areas of epidemiology, prevention, diagnosis and treatment of TB. [books.google.de]
Prognosis
Occupational history, radiology (conventional chest radiography and computed tomography) and microbiology (identification of Mycobacterium tuberculosis in sputum and pleural exudate) are helpful for the correct diagnosis, which, in turn, is important for prognosis [monaldi-archives.org]
Patients have a poor prognosis and the disease rarely ha s a chance to become one of the chronic forms. Acute silicosis, is caused by a massive outpouring of protein debris and fluid into lung sacs. [silicosis-injury-attorneys.com]
Treatment and prognosis Treatment is to remove the exposure, although silicosis may progress despite removal from the dust environment. [radiopaedia.org]
In general, the prognosis is favourable. In our case, the patient’s occupational history and radiologic features helped with the diagnosis of silicosis, but the complications of silicosis are incompletely understood. [doi.org]
Etiology
This pattern was present for both Alzheimer’s disease–related dementia and cerebrovascular disease etiologies, and persisted in analyses restricted to nonsmokers. [ajrccm.atsjournals.org]
Silicosis has as etiologic factor prolonged exposure to silica dust (sized between 3-5 microns), which causes progressive fibrosis. [pathologyatlas.ro]
If there is no progressive massive fibrosis and emphysema is present, then smoking plays a more significant role in the etiology of the emphysema and is often considered part of the etiology of the patient's disability. [web.archive.org]
Meletis and Ben Bramwell, Rheumatoid Arthritis: Etiology and Naturopathic Treatments, Alternative and Complementary Therapies, 7, 6, (347), (2001). Judy Van de Water, Hiromi Ishibashi, Ross L. Coppel and M. [doi.org]
Epidemiology
A comprehensive, and profusely illustrated description of the common and uncommon images which will be found in a wide range of tropical diseases, correlated with the clinical and laboratory findings, and the epidemiology and pathology. [books.google.de]
Business Media, 8 nov. 2000 - 789 pagini A comprehensive, and profusely illustrated description of the common and uncommon images which will be found in a wide range of tropical diseases, correlated with the clinical and laboratory findings, and the epidemiology [books.google.ro]
DHHS (NIOSH) Publication Number 2004-146 The Worker Health Chartbook 2004 is a descriptive epidemiologic reference on occupational morbidity and mortality in the United States. [cdc.gov]
Pathophysiology
Moreover, the pathophysiological mechanisms involved in silicosis make it an important risk factor for acquiring other diseases such as tuberculosis, as well as the mycoses aspergillosis and cryptococcosis. [inis.iaea.org]
Grasp the nuances of the pathophysiology of today’s major respiratory conditions—including pulmonary hypertension, COPD, asthma, environmental lung disease, sleep disorders, infections of the immunocompromised, neonatal breathing disorders, and drug-resistant [books.google.de]
Shuko Murakami, Yasumitsu Nishimura, Megumi Maeda, Naoko Kumagai, Hiroaki Hayashi, Ying Chen, Masayasu Kusaka, Takumi Kishimoto and Takemi Otsuki, Cytokine alteration and speculated immunological pathophysiology in silicosis and asbestos-related diseases [doi.org]
Prevention
[Silicotuberculosis and its prevention]. Burckhardt P. Burckhardt P. Schweiz Med Wochenschr. 1967 Jul 29;97(30):980-2. Schweiz Med Wochenschr. 1967. PMID: 5593634 German. No abstract available. [pubmed.ncbi.nlm.nih.gov]
Prevention Silicosis is prevented by avoiding inhalation of dust containing free crystalline silica. [web.archive.org]
Author information 1 Division of Respiratory Disease Studies, Centers for Disease Control and Prevention, Morgantown, WV 26505, USA. [ncbi.nlm.nih.gov]