Altogether, 86 patients with serologically verified SINV infection were recruited to the present study during the 2002 outbreak. [ncbi.nlm.nih.gov]

In this proposal we will identify i) the optimal strategy for expression of structural proteins of RVFV by recombinant Sindbis virus, ii) a system for delivery of recombinant genomes into antigen-presenting cells, and iii) the manufacturing procedure [grantome.com]

A recent study in northern Sweden revealed that in a randomly selected population-based cohort, 2.9% had SINV IgG (Figure), indicating that the virus was present in the region, although not recognized (10). [wwwnc.cdc.gov]

Apoptosis Genes presents a current overview of key genes involved in the control of apoptosis research together with thoughts on future prospects and clinical applications. [books.google.com]

• Osteoporosis

  Given the increased interest in the role of apoptosis genes in disease processes, this work will be useful to researchers investigating cancer, autoimmune disease, viral infection, cardiovascular disease, neurodegenerative disorders, AIDS, osteoporosis [books.google.com]

• Suggestibility

  These results suggest that SIN may employ a novel cell attachment/entry mechanism during infection, allowing selective targeting of colorectal cancer cells. [ncbi.nlm.nih.gov]

  These results strongly suggest that a productive Sindbis virus infection requires functional lysosomes. Thus, endocytosis is probably the main infectious mechanism for penetration of this virus into BHK-21 cells. [cdnsciencepub.com]

  However, it has been suggested that not all strains of SINV are dependent on heparan sulfate for attachment/entry and that SINV could be utilizing multiple receptors. [digitalcommons.unf.edu]

• Ataxia

  AJ, JR. (1992) A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in Ataxia-Telangiectasia. ‏ الصفحة 275 - Tumor suppressor p53 is a regulator of Bcl-2 and bax gene expression in vitro and in vivo. [books.google.com]

A similar mode of PK-I regulatory mechanism was operative in the early stages of IFN treatment, although after a prolonged treatment a net synthesis of the PK-I protein did take place. [ncbi.nlm.nih.gov]

L of live oak (Quercus virginiana) leaf infusion and the adults were fed on SINV-infected (treatments) or non-infected (controls) bovine blood. [experts.illinois.edu]

Among the remaining treatments, DENV-4 titers were highest among 15:1 DENV-4:SINV coinfection treatment and SINV first superinfection treatment, intermediate in 1:1 DENV-4:SINV coinfection treatment and lowest in 1:15 DENV-4:SINV treatment. [parasitesandvectors.biomedcentral.com]

There is no treatment for humans or vaccine for the livestock that are such important amplifiers of the virus. An experimental vaccine exists for humans, but the number of doses is limited, and there are no prospects for future manufacture. [grantome.com]

By plaque assay, salubrinal treatment had no effect on the production of either CHIKV or SINV infectious virus particles. [virologyj.biomedcentral.com]

Several viruses cause acute and chronic joint inflammation in humans, and among them, the alphaviruses are of special interest due to the increasing number of outbreaks in which they are the etiological factor. [ncbi.nlm.nih.gov]

Abstract Several viruses cause acute and chronic joint inflammation in humans, and among them, the alphaviruses are of special interest due to the increasing number of outbreaks in which they are the etiological factor. [pubmed.ncbi.nlm.nih.gov]

In this article we will summarize the current knowledge on epidemiology, clinical disease and pathogenesis of SINV infection in man. Copyright © 2016 John Wiley & Sons, Ltd. [ncbi.nlm.nih.gov]

Complete coding sequence and molecular epidemiological analysis of Sindbis virus isolates from mosquitoes and humans, Finland. Journal of General Virology, Vol. 93, Issue. Pt_9, p. 1984. CrossRef Google Scholar Sane, J. Kurkela, S. Desdouits, M. [cambridge.org]

Sindbis virus as a human pathogen-epidemiology, clinical picture and pathogenesis. Rev Med Virol. 2016;26:221–41. DOIPubMed Niklasson B, Espmark A. Ockelbo disease: arthralgia 3-4 years after infection with a Sindbis virus related agent. [wwwnc.cdc.gov]

Haemaphysalis longicornis, Ixodes nipponensis, Amblyomma testudinarium [5] and Rhipicephalus microplus. [6] In addition to tick bite, SFTSV can be transmitted from person to person through contact with blood or mucus of an infected person. [7] [8] Epidemiology [en.wikipedia.org]

The arbovirus: epidemiology and ecology & Monath T.P. 1988 pp. 87–126. Eds. Boca Raton, FL : CRC Press. Google Scholar Hardy J.L, Houk E.J, Kramer L.D& Reeves W.C. 1983 Intrinsic factors affecting vector competence of mosquitoes for arboviruses. [rspb.royalsocietypublishing.org]

The pathophysiological mechanisms of musculoskeletal and rheumatic disease caused by SINV are inadequately understood. [ncbi.nlm.nih.gov]

The pathophysiological roles of H19 and its mature product miR-675 to carcinogenesis have, however, not been defined. By quantitative reverse transcription–polymerase chain reaction, both H19 and... [connection.ebscohost.com]

CONCLUSIONS: Educating the public in endemic areas to avoid mosquito exposure and use protective measures remain important prevention measures for SINV infection. [ncbi.nlm.nih.gov]

الصفحة 83 - Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. ‏ [books.google.com]

Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. [wwwnc.cdc.gov]

It has also been proposed that interaction of Dicer-2 with R2D2 prevents its binding to miRNA precursors in vitro 19. [nature.com]

This is in contrast to SINV infection in mosquito cells where SINV is a substrate for RNAi [13], [38] and svRNAs prevented viral spread between cells in Drosophila [46]. [journals.plos.org]