To accurately describe the characteristic tooth present in this syndrome, it is necessary to specify: • Solitary: the tooth present exists as the only central incisor tooth in... [causes.com]

The surgical and clinical implications of this diagnosis will be presented. [ncbi.nlm.nih.gov]

To accurately describe the characteristic tooth present, it is necessary to specify: Solitary: The tooth present exists as the only central incisor tooth in the maxilla Median: The tooth is present precisely in the midline of the maxillary alveolus (a [jpbsonline.org]

Kathryn Willson, William G Wilson Department of Pediatrics, University of Virginia Medical Center, Charlottesville, Virginia 22908, USA Abstract A child with a single central maxillary incisor and a deletion of the short arm of chromosome 18 (18p—) is presented [dx.doi.org]

• Short Stature

  When the association with short stature was recognised in 1976, the name Monosuperoincisivodontic dwarfism was given by Rappaport et al. [9], but it was soon recognised that short stature was not always present in the disorder [10]. [causes.com]

  The fifth case has an erupted SCMI and short stature. The associated SCMI in CNPAS is believed to be more than an isolated anomaly. [ncbi.nlm.nih.gov]

  Choanal stenosis requires emergency surgical treatment and short stature may require growth hormone therapy. [orpha.net]

  stature, choanal atresia/midnasal stenosis (SMMCI) syndrome. ( 9431535 ) Hall R.K....Perks A.G. 1997 [malacards.org]

  Solitary median maxillary central incisor, short stature, choanal atresia/midnasal stenosis (SMMCI) syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1997;84:651-62. 4. Rappaport EB, Ulstrom R, Gorlin RJ. [contempclindent.org]

• Weight Loss

  Weight loss by evaporation from human dentin at 22.3°C and 53.2% relative humidity has been reported to be rapid and non-linear, reaching 3.33 ± 0.63% after 7 days [ 38 ]. [journals.plos.org]

• Short Arm

  arm of chromosome 18 (18p—) is presented. [dx.doi.org]

They may have neurodevelopmental issues. [11, 12, 13, 14, 15] Workup Prenatal diagnosis options include karyotype analysis, microarray testing, ultrasonography, and magnetic resonance imaging (MRI). [emedicine.medscape.com]

The prosthetic treatment was finished with an all-ceramic crown using a zirconia frame. [jstage.jst.go.jp]

There are two treatment options that exist for replacing missing incisors. [jcrsmed.org]

[…] orthodontic treatment following consultations with an oral surgeon or periodontist and restorative dentist to ensure orthodontic alignment will facilitate the surgical, implant and restorative treatment. 2 Aspects of orthodontic treatment required for [cda-adc.ca]

Awareness of the associated features of CNPAS among the radiologist and otolaryngologist may help the diagnosis and treatment of the patient. [ncbi.nlm.nih.gov]

• Tooth transplantation is considered an advantageous treatment to replace a maxillary incisor. • Orthodontic treatment of adolescents with SMMCI syndrome can be performed successfully. [pocketdentistry.com]

Treatment and prognosis The prognosis is dependent on the type of HPE with almost all alobar and semilobar forms incompatible with extrauterine life. There may be recurrence risk for ~6% with non chromosomal sporadic HPE. [radiopaedia.org]

Mighel AS, Johnstone ED, Levene M (2009) Postnatal investigations: management and prognosis for fetuses with CNS anomalies identified in utero excluding neurosurgical problems. Prenat Diagn 29:442–449 CrossRef Google Scholar 9. [link.springer.com]

As the prognosis is good with treatment, early recognition and timely intervention is necessary. [jcnonweb.com]

The Frankfort-mandibular plane angle in orthodontic diagnosis, classification, treatment planning, and prognosis. Am J Orthod Oral Surg 1946;32:175-230. 21. Downs WB. Variations in facial relationships; their significance in treatment and prognosis. [ijdr.in]

The prognosis of holoprosencephaly depends on the severity of the malformation. [emedicine.medscape.com]

The etiology is uncertain. Genetics A missense mutation in the SHH gene (I111F) at 7q36 may be associated with SMMCI 2. [radiopaedia.org]

Etiology The aetiology is uncertain. A missense mutation in the SHH gene (I111F) at 7q36 may be associated with SMMCI. [orpha.net]

Abstract Introduction: The solitary median maxillary central incisor syndrome is a rare disease with a prevalence of 1/50000 infants, predominantly female and of unknown etiology in most cases. [omicsonline.org]

The etiology of both the conditions remains uncertain although various theories have been proposed. [contempclindent.org]

Epidemiology It is estimated to occur in 1:50,000 live births. [radiopaedia.org]

Holoprosencephaly in human embryos: epidemiologic studies of 150 cases. Teratology. 1977 Dec. 16(3):261-72. [Medline]. Orioli IM, Castilla EE. Epidemiology of holoprosencephaly: Prevalence and risk factors. [emedicine.medscape.com]

Summary Epidemiology It is estimated to occur in 1:50,000 live births. [orpha.net]

Pathophysiology A combination of genetic and environmental factors is thought to be responsible for the pathogenesis of holoprosencephaly. [emedicine.medscape.com]

PRF accelerates healing by hastened wound closure due to growth factor release and fibrin bandage. [16] It also acts like an interpositional material preventing migration of undesired cells and accelerates wound healing by forming fibrin bandage and releasing [endodontologyonweb.org]

[…] of an SMMCI tooth is unknown, although Hall et al. [1] have postulated that a critical absence of or reduction in lateral growth from the midline, on or around gestation days 37 or 38, results in premature fusion of the epithelial dental lamina, thus preventing [jpbsonline.org]

/105388 Introduction The main objective of endodontic treatment is the thorough mechanical and chemical cleaning of the entire pulp space, to achieve an appropriate disinfection degree for after filling, with an inert material and a coronal filling, preventing [ejgd.org]

After gathering all clinical records, arriving at a diagnosis, and provision of routine preventive care, restorative treatment planning began. [dentistrytoday.com]

This position may prevent food from accumulating on the cervical "table" of the crown. [slideshare.net]