In the present communication, we present two patients (one with multiple sclerosis and the other with Parkinson's disease) in whom treatment with magnetic fields produced behavioral effects which paralleled those observed in REM-sleep-deprived animals [ncbi.nlm.nih.gov]

• Fatigue

  BACKGROUND: Fatigue in military operations leads to safety and operational problems due to a decrease in alertness and performance. [ncbi.nlm.nih.gov]

  […] pilot is too fatigued to fly. [web.archive.org]

  […] of fatigue despite evidence of increased risk to health and safety. 4 5 This has led to calls for better information on the extent and consequences of the effects of fatigue on performance. 6 The problem, in practice, is at what level of fatigue does [doi.org]

• Weakness

  Some patients will experience only pain, while others may also suffer from weakness in their arms or legs. The weakness may be mild or may progress to paralysis in a relatively short period of time. [lifebridgehealth.org]

  There’s an important weakness in the experiment, however, in that participants didn’t face any penalty for signing the confession. [arstechnica.com]

  Metastasis to the spine can lead to significant adverse effects, including numbness/tingling, weakness, pain and incontinence. A significant proportion of patients who develop spinal metastasis will develop one or more of these symptoms. [dukecancerinstitute.org]

  Spinal metastases can cause neurologic symptoms including weakness, sensory loss, strange sensations, difficulty with or inability to walk, or bowel and bladder dysfunction. [urmc.rochester.edu]

  At the expressed inflammatory process there is a weakness, the person grows thin, body temperature increases. Inflammatory process at a chronic sigmoiditis sometimes extends to a visceral peritoneum with development of a perisigmoiditis. [en.medicalmed.de]

• Blurred Vision

  Lack of sleep can cause myriad symptoms: aching muscles, blurred vision, depression, color blindness, drowsiness, loss of concentration, weak immune system, dizziness, dark circles of the eyes, fainting, confusion, hallucinations, symptoms of drunkenness [world-of-lucid-dreaming.com]

  Signs of chronic sleep deprivation can also include frequent infections/illnesses, blurred vision, changes in appetite, and depression. [ccmr.cornell.edu]

• Suggestibility

  That could mean that the more sleep-deprived someone feels, the more impaired their judgment is (as the researchers suggest). [arstechnica.com]

  BACKGROUND: Sleep deprivation has been associated with obesity among adults, and accumulating data suggests that stearoyl-CoA desaturase 1 (SCD1) expression has a relevant impact on fatty acid (FA) composition of lipid pools and obesity. [ncbi.nlm.nih.gov]

  […] of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA 4 Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA Abstract Many behavioral and electrophysiological studies in animals and humans have suggested [dx.doi.org]

• Mood Swings

  These can include forgetfulness, inattentiveness, being less able to fight off infections, and even mood swings and depression. Facts about sleep deprivation Sleep deprivation is becoming more common. [columbianeurology.org]

  Lack of sleep can cause: Lack of energy Lower concentration levels and decision making abilities Headaches and dizziness Muscle aches Nausea Hand tremors Increased blood pressure Irritability and mood swings Memory lapses Hallucinations Additionally, [kidspot.com.au]

  You may feel more impatient or prone to mood swings. It can also compromise decision-making processes and creativity. If sleep deprivation continues long enough, you could start having hallucinations —seeing or hearing things that aren’t there. [healthline.com]

  They may feel angry and impulsive, have mood swings, feel sad or depressed, or lack motivation. They also may have problems paying attention, and they may get lower grades and feel stressed. [nhlbi.nih.gov]

• Emotional Outbursts

  Does your child have emotional outbursts? As parents, we all know what it feels like to be grumpy, contrary, and “not at our best” from lack of sleep. If our kids often feel this way, we owe it to them to find solutions to this problem. [drgreene.com]

• Chronic Anxiety

  “I had extreme chronic anxiety, I was super emotional and impulsive, I couldn’t manage my appetite or keep a good workout regimen,” he said. “All the metrics people measure their success by ... I was suffering in all of them." [abcnews.go.com]

• Irritability

  Irritability and loss of motivation are common outcomes of sleep deprivation. We look at each below. Irritability Sleep deprivation doesn’t just affect you. [optalert.com]

  Marine Corps were offered mental health evaluation for sleep disturbance and symptoms of blunted affect, low mood, poor concentration, inability to focus, irritability, and drowsiness. All three patients reported insomnia as their primary complaint. [ncbi.nlm.nih.gov]

  Symptoms include: Moodiness and irritability Temper tantrums The tendency to emotionally ‘explode’ at the slightest provocation Over-activity and hyperactive behaviour Daytime naps Grogginess when they wake up in the morning Reluctance to get out of bed [web.archive.org]

  The tricky thing is that sleep deprivation (insufficient sleep) can also lead to depressed mood, moodiness, and irritability. It can be difficult to decipher which came first, the depression or the sleep disturbance. [psycom.net]

• Confusion

  RESULTS: Neurological deterioration as defined as a decrease in Glasgow Coma Scale score of 2 or more, an increase in National Institute of Health Stroke Scale score by 4 or more, or a change in Confusion Assessment Method score for use in intensive care [ncbi.nlm.nih.gov]

  He also became upset, confused and paranoid. He hallucinated - at first, simple patterns like cobwebs on people's faces, or insects which were really specks of paint on the table. But soon, they became more intense, like waking dreams. [world-of-lucid-dreaming.com]

  Next, disoriented people may become confused about the place, not knowing where they are. Finally, in the extremes of disorientation, someone may not even know who they are. [sleepdisorders.about.com]

• Cognitive Impairment

  In this context, scientists have developed new experimental paradigms to artificially induce transient cognitive impairments in healthy volunteers akin to those observed in Alzheimer's disease, i.e. the Cognitive Challenge Models. [ncbi.nlm.nih.gov]

• Headache

  Often, headaches and tension are found to increase after poor sleep; occasionally this may be accompanied by feelings of dizziness and light-headedness. It is recommended that you consult your doctor if you experience symptoms such as this. [sleepio.com]

  After just one night of skimping on sleep, you'll experience changes in mood, headache, and hormone imbalances. One week of sleeping fewer than six hours a night can result in changes to more than 700 genes. [mindbodygreen.com]

  Lack of sleep can cause: Lack of energy Lower concentration levels and decision making abilities Headaches and dizziness Muscle aches Nausea Hand tremors Increased blood pressure Irritability and mood swings Memory lapses Hallucinations Additionally, [kidspot.com.au]

  That’s why people who are sleep deprived are susceptible to headaches, and part of why those who have stayed awake for 24 hours perform similarly to those with a blood alcohol content of 0.1 percent on many mental and physical tasks, he noted. [abcnews.go.com]

  It can also sometimes cause headaches. Try instead to read a fiction book or something that is inspiring or about spiritual growth. 3. [draxe.com]

• Excitement

  A. ( 1989 ) Sleep loss: A preventable cause of mania and other excited states. Journal of Clinical Psychiatry, 50 ( suppl. ), 8 – 16. Wehr, T. A. ( 1990 ) Effects of wakefulness and sleep on depression and mania. [bjp.rcpsych.org]

  Not only did this thesis shift 30m books for Dr John Gray, PhD, it has also provided the branding for his new, exciting diet plan based on Mars and Venus Supershakes. Gray's PhD, meanwhile, is from California. [web.archive.org]

  […] found to be the strongest predictor for pain in adults over 50. 5 Separate research also found that when participants cut their sleep from 7.5 to 6.5 hours a night, there were increases in the expression of genes associated with inflammation, immune excitability [articles.mercola.com]

We think that this is only possible if an extensive diagnostic workup is performed at the time of the first symptom, back pain. [jamanetwork.com]

• Slowing - Theta Waves

  Recently, through study of electroencephalograms (EEGs) in humans and local field potentials (LFPs) in nonhuman primates and rodents it was found that, during sleep deprivation, regional 'sleep-like' slow and theta (slow/theta) waves co-occur with impaired [ncbi.nlm.nih.gov]

METHODS AND STUDY DESIGN: Forty-two healthy Iranian men, aged 20-40 years old, were assigned to three groups in a randomised crossover trial involving three treatments with two-week washout periods. [ncbi.nlm.nih.gov]

Intramedullary metastases are associated with a poor prognosis. Up to two-thirds of patients die within six months of diagnosis 2. [radiopaedia.org]

A revised scoring system for preoperative evaluation of metastatic spine tumor prognosis. Spine (Phila Pa 1976). 2005;30(19):2186-91. [ Links ] 15. Tokuhashi Y, Ajiro Y, Umezawa N. [scielo.br]

Model systems of psychosis, such as schizotypy or sleep deprivation, are valuable in informing our understanding of the etiology of the disorder and aiding the development of new treatments. [ncbi.nlm.nih.gov]

Epidemiologic studies, mainly of nurses, have revealed an association between sustained night work and a 50-100% higher incidence of breast cancer. [ncbi.nlm.nih.gov]

Numerous epidemiological studies also have revealed that adults who usually slept less than five hours per night have a greatly increased risk of having or developing diabetes. [web.archive.org]

The findings suggest that the use of biological tests to study affective syndromes occurring in Klinefelter patients might yield clues regarding the existence of pathophysiological common denominators of primary and Klinefelter-associated affective disorders [ncbi.nlm.nih.gov]

Greene Reviews | 08 November 2018 This Review describes the effects of short sleep duration on cardiovascular health and diseases, and the authors discuss the main pathophysiological mechanisms involved, taking into account both experimental data and [nature.com]

Pathophysiology The etiology and pathophysiology of chronic insomnia are unknown. [doi.org]

This case demonstrates an interaction between antidepressant medication and partial sleep deprivation in the prevention of depressive mood cycles. [ncbi.nlm.nih.gov]

Centers for Disease Control and Prevention. (2010). Key sleep disorders. Retrieved August 13, 2010, from http://www.cdc.gov/sleep/disorders.htm. Centers for Disease Control and Prevention. (2010). [sleep-deprivation.com]