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Sleep Deprivation

Sleep deprivation is defined as a prolonged period without restorative sleep.


Presentation

  • In the present communication, we present two patients (one with multiple sclerosis and the other with Parkinson's disease) in whom treatment with magnetic fields produced behavioral effects which paralleled those observed in REM-sleep-deprived animals[ncbi.nlm.nih.gov]
  • CONCLUSION: medical students and residents presented sleep deprivation, indicating the need for preventive actions in the medical area. [Indexed for MEDLINE] Free full text[ncbi.nlm.nih.gov]
  • Results showed that aggression was maintained by negative reinforcement contingencies (escape from demand) and that aggression was more severe when sleep deprivation was present.[ncbi.nlm.nih.gov]
  • Abstract A case history is presented of a patient with treatable dementia of unusual pathogenesis.[ncbi.nlm.nih.gov]
  • The present study suggests that people rely predominantly on habits at the expense of goal-directed control after sleep deprivation, and this process involves the vmPFC.[ncbi.nlm.nih.gov]
Fatigue
  • Vigor, fatigue and Total Mood Disturbance were affected by each condition. Furthermore, Total Mood Disturbance and fatigue were possibly explained by changes in the cortisol levels in the combined condition.[ncbi.nlm.nih.gov]
  • Therefore, the study aimed to investigate the effects of 24-h sleep deprivation on mood, fatigue, and airline pilot competencies.[ncbi.nlm.nih.gov]
  • BACKGROUND: Fatigue in military operations leads to safety and operational problems due to a decrease in alertness and performance.[ncbi.nlm.nih.gov]
  • Content partner More information Print fact sheet Email fact sheet Related topics: Fatigue explained Fatigue fighting tips Sleep - common disorders Sleep apnoea Sleep hygiene Add to facebook Add to del.icio.us Digg this story Last updated: January 2009[web.archive.org]
Weakness
  • There’s an important weakness in the experiment, however, in that participants didn’t face any penalty for signing the confession.[arstechnica.com]
  • Lack of sleep can cause myriad symptoms: aching muscles, blurred vision, depression, color blindness, drowsiness, loss of concentration, weak immune system, dizziness, dark circles of the eyes, fainting, confusion, hallucinations, symptoms of drunkenness[world-of-lucid-dreaming.com]
  • In some cases, the deficiency leads to myopathy, with quite severe muscle weakness, especially affecting the legs and ability to walk.[web.mit.edu]
Chronic Fatigue Syndrome
  • International Chronic Fatigue Syndrome Study Group The chronic fatigue syndrome: A comprehensive approach to its definition and study. Ann Intern Med. 1994; 121 (12):953–959. [ PubMed ] [ Google Scholar ] 48. Plioplys AV, Plioplys S.[ncbi.nlm.nih.gov]
  • Similarly low serum acylcarnitine levels have been measured in patients with chronic fatigue syndrome ( 46 ), another condition with reported sleep problems ( 47 ), and l -carnitine administration has also shown some benefit in reducing fatigue ( 48 )[doi.org]
Blurred Vision
  • Lack of sleep can cause myriad symptoms: aching muscles, blurred vision, depression, color blindness, drowsiness, loss of concentration, weak immune system, dizziness, dark circles of the eyes, fainting, confusion, hallucinations, symptoms of drunkenness[world-of-lucid-dreaming.com]
  • Signs of chronic sleep deprivation can also include frequent infections/illnesses, blurred vision, changes in appetite, and depression.[ccmr.cornell.edu]
Suggestibility
  • BACKGROUND: Sleep deprivation has been associated with obesity among adults, and accumulating data suggests that stearoyl-CoA desaturase 1 (SCD1) expression has a relevant impact on fatty acid (FA) composition of lipid pools and obesity.[ncbi.nlm.nih.gov]
  • Findings suggest a robust DAergic modulation of cortical activation during the VA task, such that D2/D3R in dorsal striatum counterbalanced the stimulatory influence of D2/D3R in ventral striatum, which was not significantly disrupted by SD.[ncbi.nlm.nih.gov]
  • […] of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA 4 Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA Abstract Many behavioral and electrophysiological studies in animals and humans have suggested[dx.doi.org]
  • The findings suggest that the use of biological tests to study affective syndromes occurring in Klinefelter patients might yield clues regarding the existence of pathophysiological common denominators of primary and Klinefelter-associated affective disorders[ncbi.nlm.nih.gov]
  • These results suggest that the beneficial effects of SD may be mediated by thyroid hormones, or associated activity in the hypothalamic-pituitary-adrenal axis.[ncbi.nlm.nih.gov]
Chronic Anxiety
  • “I had extreme chronic anxiety, I was super emotional and impulsive, I couldn’t manage my appetite or keep a good workout regimen,” he said. “All the metrics people measure their success by ... I was suffering in all of them."[abcnews.go.com]
Emotional Outbursts
  • Does your child have emotional outbursts? As parents, we all know what it feels like to be grumpy, contrary, and “not at our best” from lack of sleep. If our kids often feel this way, we owe it to them to find solutions to this problem.[drgreene.com]
Irritability
  • Marine Corps were offered mental health evaluation for sleep disturbance and symptoms of blunted affect, low mood, poor concentration, inability to focus, irritability, and drowsiness. All three patients reported insomnia as their primary complaint.[ncbi.nlm.nih.gov]
  • Irritability and loss of motivation are common outcomes of sleep deprivation. We look at each below. Irritability Sleep deprivation doesn’t just affect you.[optalert.com]
  • Symptoms include: Moodiness and irritability Temper tantrums The tendency to emotionally ‘explode’ at the slightest provocation Over-activity and hyperactive behaviour Daytime naps Grogginess when they wake up in the morning Reluctance to get out of bed[web.archive.org]
  • The tricky thing is that sleep deprivation (insufficient sleep) can also lead to depressed mood, moodiness, and irritability. It can be difficult to decipher which came first, the depression or the sleep disturbance.[psycom.net]
Confusion
  • RESULTS: Neurological deterioration as defined as a decrease in Glasgow Coma Scale score of 2 or more, an increase in National Institute of Health Stroke Scale score by 4 or more, or a change in Confusion Assessment Method score for use in intensive care[ncbi.nlm.nih.gov]
  • He also became upset, confused and paranoid. He hallucinated - at first, simple patterns like cobwebs on people's faces, or insects which were really specks of paint on the table. But soon, they became more intense, like waking dreams.[world-of-lucid-dreaming.com]
  • Effects include boredom, irritability, difficulty in concentrating, confusion, and inaccurate perception of sensory stimuli.[medical-dictionary.thefreedictionary.com]
  • Next, disoriented people may become confused about the place, not knowing where they are. Finally, in the extremes of disorientation, someone may not even know who they are.[sleepdisorders.about.com]
Headache
  • After just one night of skimping on sleep, you'll experience changes in mood, headache, and hormone imbalances. One week of sleeping fewer than six hours a night can result in changes to more than 700 genes.[mindbodygreen.com]
  • Often, headaches and tension are found to increase after poor sleep; occasionally this may be accompanied by feelings of dizziness and light-headedness. It is recommended that you consult your doctor if you experience symptoms such as this.[sleepio.com]
  • Lack of sleep can cause: Lack of energy Lower concentration levels and decision making abilities Headaches and dizziness Muscle aches Nausea Hand tremors Increased blood pressure Irritability and mood swings Memory lapses Hallucinations Additionally,[kidspot.com.au]
  • That’s why people who are sleep deprived are susceptible to headaches, and part of why those who have stayed awake for 24 hours perform similarly to those with a blood alcohol content of 0.1 percent on many mental and physical tasks, he noted.[abcnews.go.com]
  • […] can cause myriad symptoms: aching muscles, blurred vision, depression, color blindness, drowsiness, loss of concentration, weak immune system, dizziness, dark circles of the eyes, fainting, confusion, hallucinations, symptoms of drunkenness, tremors, headaches[world-of-lucid-dreaming.com]
Excitement
  • Deprivation seems to heighten neural excitability.[ncbi.nlm.nih.gov]
  • A. ( 1989 ) Sleep loss: A preventable cause of mania and other excited states. Journal of Clinical Psychiatry, 50 ( suppl. ), 8 – 16. Wehr, T. A. ( 1990 ) Effects of wakefulness and sleep on depression and mania.[bjp.rcpsych.org]
  • Not only did this thesis shift 30m books for Dr John Gray, PhD, it has also provided the branding for his new, exciting diet plan based on Mars and Venus Supershakes. Gray's PhD, meanwhile, is from California.[guardian.co.uk]
Behavior Problem
  • It is known that idiopathic insomnia exists without the detectable presence of other sleep disorders, medical problems, medication or substance use or abuse, any underlying behavioral problems that could cause poor or unfulfilling sleep, and any psychiatric[web.archive.org]
  • Characteristics of Idiopathic Insomnia It is known that idiopathic insomnia exists without the detectable presence of other sleep disorders, medical problems, medication or substance use or abuse, any underlying behavioral problems that could cause poor[sleepassociation.org]
  • If your child has ADD symptoms or other behavior problems, he or she should be carefully assessed for sleep problems. If sleep disturbances are present, they need to be addressed, regardless of whether or not they are the root cause.[drgreene.com]
  • In other cases, babies may suffer from medical conditions or behavioral problems that interfere with their sleep. Parents may also overestimate how much sleep their babies need, causing babies to resist bedtime.[parentingscience.com]
  • They were consistently at greatest risk for "acting out" behavioral problems, such as aggression and oppositional or noncompliant behavior. 5 Research shows that sleep disturbances in children are not only associated with medical problems (allergies,[web.archive.org]

Treatment

  • Total sleep deprivation and sertraline therapy is introduced to correlate with the rapid treatment response and BDNF changes in this study.[ncbi.nlm.nih.gov]
  • RESULTS: Among the 217 completers, 67.7% showed response and 54.4% reached remission at the end of the treatment.[ncbi.nlm.nih.gov]
  • METHODS AND STUDY DESIGN: Forty-two healthy Iranian men, aged 20-40 years old, were assigned to three groups in a randomised crossover trial involving three treatments with two-week washout periods.[ncbi.nlm.nih.gov]
  • These results provide preliminary evidence of the potential effectiveness of TMS for the treatment of cognitive impairment.[ncbi.nlm.nih.gov]
  • Similar treatment protocols have not been investigated in patients with pharmacotherapy refractory insomnia and generalized anxiety disorder.[ncbi.nlm.nih.gov]

Prognosis

  • What Is the Prognosis for Sleep Disorders? Nightmare disorder Most children outgrow this disorder. A small number of children report this disorder persisting into adulthood and becoming a lifelong problem.[emedicinehealth.com]

Etiology

  • Model systems of psychosis, such as schizotypy or sleep deprivation, are valuable in informing our understanding of the etiology of the disorder and aiding the development of new treatments.[ncbi.nlm.nih.gov]
  • Pathophysiology The etiology and pathophysiology of chronic insomnia are unknown.[doi.org]
  • It remains intriguing that the only amino acid and biogenic amines shown here to increase during acute sleep deprivation (serotonin, tryptophan, taurine) have been implicated in the etiology of depression ( 30 , 33 , 34 , 38 , 39 ).[doi.org]
  • It remains intriguing that the only amino acid and biogenic amines shown here to increase during acute sleep deprivation (serotonin, tryptophan, taurine) have been implicated in the etiology of depression ( 30, 33, 34, 38, 39 ).[doi.org]

Epidemiology

  • Epidemiologic studies, mainly of nurses, have revealed an association between sustained night work and a 50-100% higher incidence of breast cancer.[ncbi.nlm.nih.gov]
  • Epidemiologic evidence indicates that chronic sleep curtailment increases risk of developing obesity, but the mechanisms behind this relation are largely unknown.[ncbi.nlm.nih.gov]
  • Epidemiological studies have shown that short sleep duration is associated with increased incidence of cardiovascular diseases, such as coronary artery disease, hypertension, arrhythmias, diabetes and obesity, after adjustment for socioeconomic and demographic[ncbi.nlm.nih.gov]
  • Navbar Search Filter Mobile Microsite Search Term Article Navigation 1 Mailman School of Public Health, Department of Epidemiology, Columbia University, College of Physicians and Surgeons, New York, NY * Address correspondence to: James Gangwisch, Columbia[doi.org]
  • Numerous epidemiological studies also have revealed that adults who usually slept less than five hours per night have a greatly increased risk of having or developing diabetes.[web.archive.org]
Sex distribution
Age distribution

Pathophysiology

  • The findings suggest that the use of biological tests to study affective syndromes occurring in Klinefelter patients might yield clues regarding the existence of pathophysiological common denominators of primary and Klinefelter-associated affective disorders[ncbi.nlm.nih.gov]
  • Sleep deprivation thus represents a promising but possibly unspecific experimental model that may be helpful to further improve our understanding of the underlying mechanisms in the pathophysiology of psychosis and aid the development of antipsychotic[ncbi.nlm.nih.gov]
  • Greene Reviews 08 November 2018 This Review describes the effects of short sleep duration on cardiovascular health and diseases, and the authors discuss the main pathophysiological mechanisms involved, taking into account both experimental data and clinical[nature.com]
  • ., 2001 ) and these neural substrates are implicated in the pathophysiology of schizophrenia and the therapeutic actions of antipsychotics ( Geyer et al., 2001 ).[jneurosci.org]
  • Pathophysiology The etiology and pathophysiology of chronic insomnia are unknown.[doi.org]

Prevention

  • The small and heterogeneous sample size prevents us from making more definitive conclusions based on statistical analyses.[ncbi.nlm.nih.gov]
  • Training induces the decrease of TNF-α concentration after TSD and prevents the increase of MCP-1 after sleep recovery. Before training, IL-6 concentrations increased.[ncbi.nlm.nih.gov]
  • This case demonstrates an interaction between antidepressant medication and partial sleep deprivation in the prevention of depressive mood cycles.[ncbi.nlm.nih.gov]
  • The results suggest that SD and nicotine may delay wound healing and that Se supplementation may accelerate wound healing by preventing nicotine-induced oxidative stress and lipid peroxidation.[doi.org]
  • We suggest that modafinil may reinforce the action of SD, possibly by preventing daytime naps and microsleep, and may sustain the antidepressant effect of SD, possibly by stabilizing the resynchronization between the circadian clock and the sleep-wake[ncbi.nlm.nih.gov]

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Last updated: 2019-06-28 11:41