In the present communication, we present two patients (one with multiple sclerosis and the other with Parkinson's disease) in whom treatment with magnetic fields produced behavioral effects which paralleled those observed in REM-sleep-deprived animals [ncbi.nlm.nih.gov]

• Fatigue

  Therefore, the study aimed to investigate the effects of 24-h sleep deprivation on mood, fatigue, and airline pilot competencies. [ncbi.nlm.nih.gov]

  […] pilot is too fatigued to fly. [faa.gov]

  […] of fatigue despite evidence of increased risk to health and safety. 4 5 This has led to calls for better information on the extent and consequences of the effects of fatigue on performance. 6 The problem, in practice, is at what level of fatigue does [doi.org]

• Excessive Daytime Sleepiness

  The main effect of sleep deprivation is excessive daytime sleepiness, which can lead to traffic accidents and workplace injuries. Sleep deprivation has both short- and long-term impacts on your health. [pamf.org]

  Modafinil is primarily used to treat the symptoms of excessive daytime sleepiness ( EDS ) in people with narcolepsy. See also excessive daytime sleepiness ( EDS ) and narcolepsy. [healthysleep.med.harvard.edu]

  Individuals with excessive daytime sleepiness, a well-recognized symptom of insomnia, often experience micro sleep episodes during periods of Excessive Daytime Sleepiness. [sleepdex.org]

• Weakness

  Some patients will experience only pain, while others may also suffer from weakness in their arms or legs. The weakness may be mild or may progress to paralysis in a relatively short period of time. [lifebridgehealth.org]

  Metastasis to the spine can lead to significant adverse effects, including numbness/tingling, weakness, pain and incontinence. A significant proportion of patients who develop spinal metastasis will develop one or more of these symptoms. [dukecancerinstitute.org]

  There’s an important weakness in the experiment, however, in that participants didn’t face any penalty for signing the confession. [arstechnica.com]

  Spinal metastases can cause neurologic symptoms including weakness, sensory loss, strange sensations, difficulty with or inability to walk, or bowel and bladder dysfunction. [urmc.rochester.edu]

  At the expressed inflammatory process there is a weakness, the person grows thin, body temperature increases. Inflammatory process at a chronic sigmoiditis sometimes extends to a visceral peritoneum with development of a perisigmoiditis. [en.medicalmed.de]

• Hypersomnia

  Forced awakening prior to MSLT may permit sleep deprivation or delayed sleep phase syndrome to masquerade as narcolepsy or idiopathic central nervous system (CNS) hypersomnia. [ncbi.nlm.nih.gov]

  Sleep disturbance, described as insomnia or hypersomnia, is one of the primary symptoms of major depressive disorder. 1 People struggling with depression are likely to have difficulty falling asleep or staying asleep. [psycom.net]

  Resources Microsleep Circadian System Sleep Deprivation View All Sleep Disorders Disorders Insomnias Obstructive Sleep Apnea Restless Legs Syndrome (RLS) Rhythmic Movement Disorder (RMD) Sleep Bruxism Exploding Head Syndrome View All More Disorders Hypersomnias [tuck.com]

  None had impaired cognition, complaints of insomnia or hypersomnias, or any significant health problems. They were not taking any medications known to affect sleep. [primarypsychiatry.com]

• Chronic Fatigue Syndrome

  International Chronic Fatigue Syndrome Study Group The chronic fatigue syndrome: A comprehensive approach to its definition and study. Ann Intern Med. 1994; 121 (12):953–959. [ PubMed ] [ Google Scholar ] 48. Plioplys AV, Plioplys S. [ncbi.nlm.nih.gov]

  Similarly low serum acylcarnitine levels have been measured in patients with chronic fatigue syndrome ( 46 ), another condition with reported sleep problems ( 47 ), and l -carnitine administration has also shown some benefit in reducing fatigue ( 48 ) [doi.org]

• Blurred Vision

  Lack of sleep can cause myriad symptoms: aching muscles, blurred vision, depression, color blindness, drowsiness, loss of concentration, weak immune system, dizziness, dark circles of the eyes, fainting, confusion, hallucinations, symptoms of drunkenness [world-of-lucid-dreaming.com]

  Signs of chronic sleep deprivation can also include frequent infections/illnesses, blurred vision, changes in appetite, and depression. [ccmr.cornell.edu]

• Suggestibility

  BACKGROUND: Sleep deprivation has been associated with obesity among adults, and accumulating data suggests that stearoyl-CoA desaturase 1 (SCD1) expression has a relevant impact on fatty acid (FA) composition of lipid pools and obesity. [ncbi.nlm.nih.gov]

  That could mean that the more sleep-deprived someone feels, the more impaired their judgment is (as the researchers suggest). [arstechnica.com]

  The evening condition (i.e. at the end of day spent awake) was intermediate between the two, suggesting that wakefulness causes progressive changes that build up over time. [blogs.discovermagazine.com]

  […] of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA 4 Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA Abstract Many behavioral and electrophysiological studies in animals and humans have suggested [dx.doi.org]

• Anxiety Disorder

  The case of a 59-year-old woman psychiatrically hospitalized with comorbid insomnia, suicidal ideation, and generalized anxiety disorder is presented. [ncbi.nlm.nih.gov]

  Article Navigation 1 Mood and Anxiety Disorders Program, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA 2 Psychiatric University Hospital, Zurich, Switzerland * Address correspondence [doi.org]

• Mood Swings

  These can include forgetfulness, inattentiveness, being less able to fight off infections, and even mood swings and depression. Facts about sleep deprivation Sleep deprivation is becoming more common. [columbianeurology.org]

  In humans, lack of sleep leads to impaired memory and reduced cognitive abilities, and, if the deprivation persists, mood swings and even hallucinations. [ncbi.nlm.nih.gov]

  Lack of sleep can cause: Lack of energy Lower concentration levels and decision making abilities Headaches and dizziness Muscle aches Nausea Hand tremors Increased blood pressure Irritability and mood swings Memory lapses Hallucinations Additionally, [kidspot.com.au]

  They may feel angry and impulsive, have mood swings, feel sad or depressed, or lack motivation. They also may have problems paying attention, and they may get lower grades and feel stressed. [nhlbi.nih.gov]

• Suicidal Ideation

  The case of a 59-year-old woman psychiatrically hospitalized with comorbid insomnia, suicidal ideation, and generalized anxiety disorder is presented. [ncbi.nlm.nih.gov]

  ideation (with or without a plan) Symptoms cause significant distress in social, occupational, or other areas of functioning The emotional symptoms that accompany depression are far more significant than moodiness or depressed mood. [psycom.net]

  Page, Assessing Interpersonal and Mood Factors to Predict Trajectories of Suicidal Ideation within an Inpatient Setting, Journal of Affective Disorders, 10.1016/j.jad.2019.04.029, (2019). [dx.doi.org]

• Emotional Outbursts

  Does your child have emotional outbursts? As parents, we all know what it feels like to be grumpy, contrary, and “not at our best” from lack of sleep. If our kids often feel this way, we owe it to them to find solutions to this problem. [drgreene.com]

• Insomnia

  The case of a 59-year-old woman psychiatrically hospitalized with comorbid insomnia, suicidal ideation, and generalized anxiety disorder is presented. [ncbi.nlm.nih.gov]

  Idiopathic insomnia is a form of chronic insomnia that is not identified by visible signs of its cause. [sleepassociation.org]

  Idiopathic insomnia is a form of chronic insomnia that contains no visible signs of its cause. [web.archive.org]

• Irritability

  Irritability and loss of motivation are common outcomes of sleep deprivation. We look at each below. Irritability Sleep deprivation doesn’t just affect you. [optalert.com]

  Marine Corps were offered mental health evaluation for sleep disturbance and symptoms of blunted affect, low mood, poor concentration, inability to focus, irritability, and drowsiness. All three patients reported insomnia as their primary complaint. [ncbi.nlm.nih.gov]

  “It is common for managers and colleagues to look at a lack of focus or motivation, irritability, and bad decision making as being caused by poor training, organizational politics or the work environment. [hult.edu]

  Symptoms include: Moodiness and irritability Temper tantrums The tendency to emotionally ‘explode’ at the slightest provocation Over-activity and hyperactive behaviour Daytime naps Grogginess when they wake up in the morning Reluctance to get out of bed [web.archive.org]

• Stroke

  Anxiety Drowsiness, leading to drowsy driving Forgetfulness Distractibility Decreased performance and alertness Memory and cognitive impairment Stressed relationships Occupational injury Automobile injury Long-term: High blood pressure Heart attack Stroke [pamf.org]

  Abstract Sleep deprivation is a major source of morbidity with widespread health effects, including increased risk of hypertension, diabetes, obesity, heart attack, and stroke. [ncbi.nlm.nih.gov]

  A stroke worsened by sleep deprivation even caused the death of a Chinese man after binge-watching soccer for 48 hours. So close that laptop and get some shut-eye. [motherboard.vice.com]

• Confusion

  RESULTS: Neurological deterioration as defined as a decrease in Glasgow Coma Scale score of 2 or more, an increase in National Institute of Health Stroke Scale score by 4 or more, or a change in Confusion Assessment Method score for use in intensive care [ncbi.nlm.nih.gov]

  He also became upset, confused and paranoid. He hallucinated - at first, simple patterns like cobwebs on people's faces, or insects which were really specks of paint on the table. But soon, they became more intense, like waking dreams. [world-of-lucid-dreaming.com]

  Effects include boredom, irritability, difficulty in concentrating, confusion, and inaccurate perception of sensory stimuli. [medical-dictionary.thefreedictionary.com]

• Cognitive Impairment

  In this context, scientists have developed new experimental paradigms to artificially induce transient cognitive impairments in healthy volunteers akin to those observed in Alzheimer's disease, i.e. the Cognitive Challenge Models. [ncbi.nlm.nih.gov]

  Short-term: Anxiety Drowsiness, leading to drowsy driving Forgetfulness Distractibility Decreased performance and alertness Memory and cognitive impairment Stressed relationships Occupational injury Automobile injury Long-term: High blood pressure Heart [pamf.org]

We think that this is only possible if an extensive diagnostic workup is performed at the time of the first symptom, back pain. [jamanetwork.com]

• Hypoglycemia

  OBJECTIVE: To ascertain whether hypoglycemia in association with sleep deprivation causes greater cognitive dysfunction than hypoglycemia alone and protracts cognitive recovery after normoglycemia is restored. [ncbi.nlm.nih.gov]

  J Clin Endocrinol Metab 95 : 2963 – 2968 6. 2007 Sleep loss alters basal metabolic hormone secretion and modulates the dynamic counterregulatory response to hypoglycemia. [doi.org]

  Another commonly found condition in fibromyalgia which has nervous related symptoms is reactive hypoglycemia. [web.mit.edu]

Sleep deprivation treatment, its immediate but short-lived beneficial effect, may have a role in the treatment of the ultra-short depressions encountered in very rapid cycling. [ncbi.nlm.nih.gov]

Intramedullary metastases are associated with a poor prognosis. Up to two-thirds of patients die within six months of diagnosis 2. [radiopaedia.org]

A revised scoring system for preoperative evaluation of metastatic spine tumor prognosis. Spine (Phila Pa 1976). 2005;30(19):2186-91. [ Links ] 15. Tokuhashi Y, Ajiro Y, Umezawa N. [scielo.br]

Model systems of psychosis, such as schizotypy or sleep deprivation, are valuable in informing our understanding of the etiology of the disorder and aiding the development of new treatments. [ncbi.nlm.nih.gov]

Epidemiologic studies, mainly of nurses, have revealed an association between sustained night work and a 50-100% higher incidence of breast cancer. [ncbi.nlm.nih.gov]

Numerous epidemiological studies also have revealed that adults who usually slept less than five hours per night have a greatly increased risk of having or developing diabetes. [web.archive.org]

The findings suggest that the use of biological tests to study affective syndromes occurring in Klinefelter patients might yield clues regarding the existence of pathophysiological common denominators of primary and Klinefelter-associated affective disorders [ncbi.nlm.nih.gov]

Greene Reviews | 08 November 2018 This Review describes the effects of short sleep duration on cardiovascular health and diseases, and the authors discuss the main pathophysiological mechanisms involved, taking into account both experimental data and [nature.com]

Pathophysiology The etiology and pathophysiology of chronic insomnia are unknown. [doi.org]

This case demonstrates an interaction between antidepressant medication and partial sleep deprivation in the prevention of depressive mood cycles. [ncbi.nlm.nih.gov]

The results suggest that SD and nicotine may delay wound healing and that Se supplementation may accelerate wound healing by preventing nicotine-induced oxidative stress and lipid peroxidation. [doi.org]