In the present communication, we present two patients (one with multiple sclerosis and the other with Parkinson's disease) in whom treatment with magnetic fields produced behavioral effects which paralleled those observed in REM-sleep-deprived animals [ncbi.nlm.nih.gov]

• Fatigue

  Therefore, the study aimed to investigate the effects of 24-h sleep deprivation on mood, fatigue, and airline pilot competencies. [ncbi.nlm.nih.gov]

  […] pilot is too fatigued to fly. [faa.gov]

  […] of fatigue despite evidence of increased risk to health and safety. 4 5 This has led to calls for better information on the extent and consequences of the effects of fatigue on performance. 6 The problem, in practice, is at what level of fatigue does [doi.org]

• Weakness

  Some patients will experience only pain, while others may also suffer from weakness in their arms or legs. The weakness may be mild or may progress to paralysis in a relatively short period of time. [lifebridgehealth.org]

  Metastasis to the spine can lead to significant adverse effects, including numbness/tingling, weakness, pain and incontinence. A significant proportion of patients who develop spinal metastasis will develop one or more of these symptoms. [dukecancerinstitute.org]

  There’s an important weakness in the experiment, however, in that participants didn’t face any penalty for signing the confession. [arstechnica.com]

  Spinal metastases can cause neurologic symptoms including weakness, sensory loss, strange sensations, difficulty with or inability to walk, or bowel and bladder dysfunction. [urmc.rochester.edu]

  At the expressed inflammatory process there is a weakness, the person grows thin, body temperature increases. Inflammatory process at a chronic sigmoiditis sometimes extends to a visceral peritoneum with development of a perisigmoiditis. [en.medicalmed.de]

• Collapse

  Notably, the marked neuroprotective effects of LLPF, which did not show obvious free-radical scavenging activity in vitro, could be attributed to its strong effects on inhibiting Ca 2+ influx and mitochondrial membrane potential collapse. [ncbi.nlm.nih.gov]

  Tumors around the spinal bones (vertebrae) can cause pain and, on occasion, collapse of the vertebrae. [lifebridgehealth.org]

  Vertebroplasty / Kyphoplasty When fractured or collapsed vertebrae result from a metastatic spine tumor, a surgical bone cement may be injected directly into the collapsed vertebra to provide support and stabilize the spine. [dukecancerinstitute.org]

  "Prolonged stress with sleep deprivation will lead to a physiological exhaustion of the body's defense mechanisms, physical collapse, and with the potential for various ensuing illnesses," Horne wrote. [content.time.com]

  I'm jealous of those who can turn off their bedroom light, sink into their soft, fluffy pillow and drift away for eight blissful hours I'd rather collapse on to the sofa in my pyjamas at 8pm instead of getting cosy with my husband, and I'm sure he feels [dailymail.co.uk]

• Anorexia

  Literature Number of times cited according to CrossRef: 52 Ali Kandeger, Yavuz Selvi and Deniz Kocoglu Tanyer, The effects of individual circadian rhythm differences on insomnia, impulsivity, and food addiction, Eating and Weight Disorders - Studies on Anorexia [doi.org]

  Caterina Lombardo, Sleep and obesity: an introduction, Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity, 21, 1, (1), (2016). Bernd Schultes, Manfred Hallschmid, Henrik Oster, Britta Wilms and Sebastian M. [dx.doi.org]

• Malaise

  You may have a feeling of malaise, which might manifest as feeling run-down or simply "not well." You might have aches or pains in your body. This may lead to a diagnosis of fibromyalgia or other chronic pain conditions. [sleepdisorders.about.com]

  The results can include increased sleep disruption, feelings of malaise, performance errors, uncontrollable falling asleep during waking hours, negative moods and problems with social interaction, inefficient communication and accidents. [thedoctorwillseeyounow.com]

  Generally, sleep deprivation may result in: aching muscles confusion, memory lapses or loss depression development of false memory hypnagogic and hypnopompic hallucinations during falling asleep and waking, which are entirely normal hand tremor headaches malaise [en.wikipedia.org]

  At least one of the following forms of daytime impairment related to the nighttime sleep difficulty is reported by the patient: Fatigue or malaise Attention, concentration, or memory impairment Social or vocational dysfunction or poor school performance [ncbi.nlm.nih.gov]

• Snoring

  Sleep disorder – problems such as sleep apnoea, snoring and periodic limb movement disorder can disturb the person’s sleep many times during the night. [web.archive.org]

  Many people don’t think of snoring as a sleep disorder, for instance, but snoring can be a sign of sleep apnea, which causes breathing interruptions during sleep and can result in serious health complications or death. [sleep-deprivation.com]

• Overeating

  This suggests that sleep debt is perhaps best understood as resulting in additional wakefulness that has a neurobiological "cost" which accumulates over time. [ncbi.nlm.nih.gov]

  The study used a cross over randomised control design (table 2 ). [doi.org]

  Without sleep, however, participants performed equally bad when the dots were over neutral and emotional images. [medicaldaily.com]

• Bruxism

  Examples of sleeping disorders include: Insomnia Narcolepsy Night terrors REM sleep behavior disorder Restless leg syndrome Sleep apnea Sleepwalking Snoring Teeth grinding, or bruxism. Popular beliefs about sleep disorders are sometimes misleading. [sleep-deprivation.com]

  The Body's Thermoregulation During Sleep View All Resources Microsleep Circadian System Sleep Deprivation View All Sleep Disorders Disorders Insomnias Obstructive Sleep Apnea Restless Legs Syndrome (RLS) Rhythmic Movement Disorder (RMD) Sleep Bruxism [tuck.com]

  Hypersomnia Narcolepsy (daytime sleepiness) Sleep Apnea (interrupted sleep) which involves snoring problems Sleepwalking Restless Legs Syndrome (RLS) Jet Lag DSPS (Delayed sleep phase syndrome) Snoring Night Sweats Baby Sleep problems Enuresis or Bedwetting Bruxism [easynight.org]

• Blurred Vision

  Lack of sleep can cause myriad symptoms: aching muscles, blurred vision, depression, color blindness, drowsiness, loss of concentration, weak immune system, dizziness, dark circles of the eyes, fainting, confusion, hallucinations, symptoms of drunkenness [world-of-lucid-dreaming.com]

  Signs of chronic sleep deprivation can also include frequent infections/illnesses, blurred vision, changes in appetite, and depression. [ccmr.cornell.edu]

• Suggestibility

  BACKGROUND: Sleep deprivation has been associated with obesity among adults, and accumulating data suggests that stearoyl-CoA desaturase 1 (SCD1) expression has a relevant impact on fatty acid (FA) composition of lipid pools and obesity. [ncbi.nlm.nih.gov]

  That could mean that the more sleep-deprived someone feels, the more impaired their judgment is (as the researchers suggest). [arstechnica.com]

  The evening condition (i.e. at the end of day spent awake) was intermediate between the two, suggesting that wakefulness causes progressive changes that build up over time. [blogs.discovermagazine.com]

  […] of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA 4 Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA Abstract Many behavioral and electrophysiological studies in animals and humans have suggested [dx.doi.org]

• Anxiety Disorder

  The case of a 59-year-old woman psychiatrically hospitalized with comorbid insomnia, suicidal ideation, and generalized anxiety disorder is presented. [ncbi.nlm.nih.gov]

  Article Navigation 1 Mood and Anxiety Disorders Program, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA 2 Psychiatric University Hospital, Zurich, Switzerland * Address correspondence [doi.org]

• Mood Swings

  These can include forgetfulness, inattentiveness, being less able to fight off infections, and even mood swings and depression. Facts about sleep deprivation Sleep deprivation is becoming more common. [columbianeurology.org]

  In humans, lack of sleep leads to impaired memory and reduced cognitive abilities, and, if the deprivation persists, mood swings and even hallucinations. [ncbi.nlm.nih.gov]

  Lack of sleep can cause: Lack of energy Lower concentration levels and decision making abilities Headaches and dizziness Muscle aches Nausea Hand tremors Increased blood pressure Irritability and mood swings Memory lapses Hallucinations Additionally, [kidspot.com.au]

  They may feel angry and impulsive, have mood swings, feel sad or depressed, or lack motivation. They also may have problems paying attention, and they may get lower grades and feel stressed. [nhlbi.nih.gov]

• Addictive Behavior

  Neuroscientists study the brain mechanisms that establish and maintain addiction in order to identify and characterize variables that affect risk (for example, genotype, environment, and experience) and to develop methods for treating addictive behavior [books.nap.edu]

  Grant, Sleepiness and cognition in young adults who gamble and use alcohol, Journal of Behavioral Addictions, 3, 3, (166), (2014). Beth M. [dx.doi.org]

• Emotional Outbursts

  Does your child have emotional outbursts? As parents, we all know what it feels like to be grumpy, contrary, and “not at our best” from lack of sleep. If our kids often feel this way, we owe it to them to find solutions to this problem. [drgreene.com]

• Irritability

  Irritability and loss of motivation are common outcomes of sleep deprivation. We look at each below. Irritability Sleep deprivation doesn’t just affect you. [optalert.com]

  Marine Corps were offered mental health evaluation for sleep disturbance and symptoms of blunted affect, low mood, poor concentration, inability to focus, irritability, and drowsiness. All three patients reported insomnia as their primary complaint. [ncbi.nlm.nih.gov]

  “It is common for managers and colleagues to look at a lack of focus or motivation, irritability, and bad decision making as being caused by poor training, organizational politics or the work environment. [hult.edu]

  Symptoms include: Moodiness and irritability Temper tantrums The tendency to emotionally ‘explode’ at the slightest provocation Over-activity and hyperactive behaviour Daytime naps Grogginess when they wake up in the morning Reluctance to get out of bed [web.archive.org]

• Stroke

  Anxiety Drowsiness, leading to drowsy driving Forgetfulness Distractibility Decreased performance and alertness Memory and cognitive impairment Stressed relationships Occupational injury Automobile injury Long-term: High blood pressure Heart attack Stroke [pamf.org]

  Abstract Sleep deprivation is a major source of morbidity with widespread health effects, including increased risk of hypertension, diabetes, obesity, heart attack, and stroke. [ncbi.nlm.nih.gov]

  A stroke worsened by sleep deprivation even caused the death of a Chinese man after binge-watching soccer for 48 hours. So close that laptop and get some shut-eye. [motherboard.vice.com]

• Confusion

  RESULTS: Neurological deterioration as defined as a decrease in Glasgow Coma Scale score of 2 or more, an increase in National Institute of Health Stroke Scale score by 4 or more, or a change in Confusion Assessment Method score for use in intensive care [ncbi.nlm.nih.gov]

  He also became upset, confused and paranoid. He hallucinated - at first, simple patterns like cobwebs on people's faces, or insects which were really specks of paint on the table. But soon, they became more intense, like waking dreams. [world-of-lucid-dreaming.com]

  Effects include boredom, irritability, difficulty in concentrating, confusion, and inaccurate perception of sensory stimuli. [medical-dictionary.thefreedictionary.com]

• Cognitive Impairment

  In this context, scientists have developed new experimental paradigms to artificially induce transient cognitive impairments in healthy volunteers akin to those observed in Alzheimer's disease, i.e. the Cognitive Challenge Models. [ncbi.nlm.nih.gov]

  Short-term: Anxiety Drowsiness, leading to drowsy driving Forgetfulness Distractibility Decreased performance and alertness Memory and cognitive impairment Stressed relationships Occupational injury Automobile injury Long-term: High blood pressure Heart [pamf.org]

• Headache

  After just one night of skimping on sleep, you'll experience changes in mood, headache, and hormone imbalances. One week of sleeping fewer than six hours a night can result in changes to more than 700 genes. [mindbodygreen.com]

  Often, headaches and tension are found to increase after poor sleep; occasionally this may be accompanied by feelings of dizziness and light-headedness. It is recommended that you consult your doctor if you experience symptoms such as this. [sleepio.com]

  That’s why people who are sleep deprived are susceptible to headaches, and part of why those who have stayed awake for 24 hours perform similarly to those with a blood alcohol content of 0.1 percent on many mental and physical tasks, he noted. [abcnews.go.com]

  […] can cause myriad symptoms: aching muscles, blurred vision, depression, color blindness, drowsiness, loss of concentration, weak immune system, dizziness, dark circles of the eyes, fainting, confusion, hallucinations, symptoms of drunkenness, tremors, headaches [world-of-lucid-dreaming.com]

We think that this is only possible if an extensive diagnostic workup is performed at the time of the first symptom, back pain. [jamanetwork.com]

Sleep deprivation treatment, its immediate but short-lived beneficial effect, may have a role in the treatment of the ultra-short depressions encountered in very rapid cycling. [ncbi.nlm.nih.gov]

Intramedullary metastases are associated with a poor prognosis. Up to two-thirds of patients die within six months of diagnosis 2. [radiopaedia.org]

A revised scoring system for preoperative evaluation of metastatic spine tumor prognosis. Spine (Phila Pa 1976). 2005;30(19):2186-91. [ Links ] 15. Tokuhashi Y, Ajiro Y, Umezawa N. [scielo.br]

Model systems of psychosis, such as schizotypy or sleep deprivation, are valuable in informing our understanding of the etiology of the disorder and aiding the development of new treatments. [ncbi.nlm.nih.gov]

Epidemiologic studies, mainly of nurses, have revealed an association between sustained night work and a 50-100% higher incidence of breast cancer. [ncbi.nlm.nih.gov]

Numerous epidemiological studies also have revealed that adults who usually slept less than five hours per night have a greatly increased risk of having or developing diabetes. [web.archive.org]

The findings suggest that the use of biological tests to study affective syndromes occurring in Klinefelter patients might yield clues regarding the existence of pathophysiological common denominators of primary and Klinefelter-associated affective disorders [ncbi.nlm.nih.gov]

Greene Reviews | 08 November 2018 This Review describes the effects of short sleep duration on cardiovascular health and diseases, and the authors discuss the main pathophysiological mechanisms involved, taking into account both experimental data and [nature.com]

Pathophysiology The etiology and pathophysiology of chronic insomnia are unknown. [doi.org]

This case demonstrates an interaction between antidepressant medication and partial sleep deprivation in the prevention of depressive mood cycles. [ncbi.nlm.nih.gov]

The results suggest that SD and nicotine may delay wound healing and that Se supplementation may accelerate wound healing by preventing nicotine-induced oxidative stress and lipid peroxidation. [doi.org]