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Solanaceous Alkaloid Poisoning

Alkaloids Solanaceous


Presentation

  • Continuous flow centrifugation may be used in the practice of the present invention.[google.com]
  • This reference guide will be the must-have of any internist or medical professional, as it takes a vast quantity of data across a sweeping grid of disorders, diseases, and presentations, and boils them down to individual parts, facilely indexed, and located[books.google.com]
  • He presently directs studies on metabolic pathways involved in liver disease, particularly related to mitochondrial energy regulation and cell death.[books.google.com]
  • Activated charcoal can bind tropane alkaloids and may be administered if patients present within 1-2 hours of ingestion and bowel sounds are present.[calpoison.org]
  • If the patient presents with stupor or coma, treatment may include dextrose, thiamine, naloxone, etc. Otherwise the main component of management is support and observation.[erowid.org]
Rhinitis
  • Also used to treat certain heart conditions, to control the symptoms of Parkinson's disease and rhinitis.[drugbank.ca]
Fever
  • ) Anemone patens All partsInternal poisoning: ranunculin Prickly lettuce Lactuca serriola Young fresh plants are poisonous; mature plants and young stages after drying appear to be non-toxic.Internal poisoning: unknown Ragweed Ambrosia spp.PollenHay fever[www1.agric.gov.ab.ca]
  • Press Release of Department of Health (7 September 2016) : Interdepartmental Coordinating Committee on Mosquito-borne Diseases meets on local cases of dengue fever and Zika virus infection (with photo) Press Release of Department of Health (1 September[cmchk.org.hk]
  • Several patients were comatose with episodes of convulsive twitching and violent fits of fever. In many patients, there were signs of peripheral circulatory collapse.[smithsonianmag.com]
  • In more severe cases, hallucinations , loss of sensation, paralysis , fever, jaundice, dilated pupils , hypothermia and death have been reported.[flipper.diff.org]
  • In more severe cases, hallucinations , loss of sensation, paralysis , fever , jaundice , dilated pupils , hypothermia , and death have been reported. [2] [3] [4] Ingestion of solanine in moderate amounts can cause death.[en.wikipedia.org]
Fatigue
  • Lebowitz treats the chronically ill patient with fatigue, intestinal issues, depression, autoimmune conditions, etc.[drnoahlebowitz.com]
Decreased Bowel Sounds
  • Dry mouth, tachycardia, decreased bowel sounds and agitation are all characteristic of both syndromes.[calpoison.org]
Absent Bowel Sounds
  • Anticholinergic findings suggestive of poisoning include hyperthermia, dry mouth, tachycardia, blurred vision, flushed dry skin, absent bowel sounds, urinary retention, agitation, hallucinations, lethargy, mumbling speech, undressing behavior (generally[calpoison.org]
Tachycardia
  • The female patient, aged 32, developed symptoms and signs compatible with solanaceous alkaloid poisoning on August 14, including dilated pupils, dry mouth, acute retention of urine and tachycardia (abnormally high heart rate), about 30 minutes after consuming[info.gov.hk]
  • Dry mouth, tachycardia, decreased bowel sounds and agitation are all characteristic of both syndromes.[calpoison.org]
  • Symptoms include mydriasis; cycloplegia; flushed, warm, dry skin; dry mouth; ileus; urinary retention; tachycardia; hyper or hypotension; delirium with hallucinations; jerky, myoclonic movements; choreoathetosis; hyperthermia; coma; respiratory arrest[erowid.org]
Hypertension
  • […] cardiovascular disease, gangrene, asthma, glaucoma, and GI/GU obstruction.(2,7,10) Thus its use as a cholinergic agent in Jimson Weed poisoning is controversial and is generally reserved for life-threatening, intractable, anticholinergic effects including hypertension[erowid.org]
Blurred Vision
  • Solanaceous alkaloids cause anticholinergic symptoms like blurred vision, dry mouth, dizziness and confusion. They can lead to death in severe cases. So far, the DH has not received any other report of related adverse incidents.[info.gov.hk]
  • "Solanaceous alkaloids cause anticholinergic symptoms including blurred vision, dry mouth, dizziness and confusion. Deaths may result in severe cases," the spokesman added.[info.gov.hk]
  • Solanaceous alkaloids cause symptoms like blurred vision, dry mouth, dizziness and confusion. They can lead to death in severe cases. The department has not received any other report of related adverse incidents so far.[news.gov.hk]
  • Blurred vision and photophobia may be due to mydraisis and paralysis of accomodation. Seizures, paralysis, respiratory depression, and coma may ensue in severe cases.[calpoison.org]
  • [Holzman 1998] Unfortunately, beauty must be suffered for, and extensive use of belladonna as a cosmetic would lead to blurred vision, increased heart rate, and, ultimately, blindness.[sites.evergreen.edu]
Photophobia
  • Blurred vision and photophobia may be due to mydraisis and paralysis of accomodation. Seizures, paralysis, respiratory depression, and coma may ensue in severe cases.[calpoison.org]
Flushing
  • His examination was significant for dry mucus membranes and his skin was warm and flushed. On neurologic exam, he was awake, but was confused, agitated and answering “I am Batman” to all questions.[calpoison.org]
  • They include intense thirst, visual disturbance, flushed skin, and central nervous system hyperirritability. Victims become delirious, incoherent, and perform insensible antics. Heart beat may be rapid with elevated temperature.[research.vet.upenn.edu]
  • These would include incoherent speech, impaired coordination, rapid heart beat, dilated pupils, blurred vision and dry, flushed or hot skin. In extreme cases users can experience seizures, intense visual or auditory hallucination, or cardiac arrest.[aacc.org]
  • Symptoms include mydriasis; cycloplegia; flushed, warm, dry skin; dry mouth; ileus; urinary retention; tachycardia; hyper or hypotension; delirium with hallucinations; jerky, myoclonic movements; choreoathetosis; hyperthermia; coma; respiratory arrest[erowid.org]
Dizziness
  • Solanaceous alkaloids cause anticholinergic symptoms like blurred vision, dry mouth, dizziness and confusion. They can lead to death in severe cases. So far, the DH has not received any other report of related adverse incidents.[info.gov.hk]
  • "Solanaceous alkaloids cause anticholinergic symptoms including blurred vision, dry mouth, dizziness and confusion. Deaths may result in severe cases," the spokesman added.[info.gov.hk]
  • The patient developed symptoms and signs compatible with solanaceous alkaloid poisoning, including dizziness, blurring of vision and dry mouth, after consuming Chinese herbal medicines for headache and dizziness on May 28.[news.gov.hk]
  • Symptoms include nausea, diarrhea , vomiting , stomach cramps, burning of the throat, cardiac dysrhythmia , nightmare, headache and dizziness.[flipper.diff.org]
  • Symptoms include nausea, diarrhea, vomiting , stomach cramps, burning of the throat, cardiac dysrhythmia , nightmares , headache, dizziness, itching, eczema, thyroid problems, and inflammation and pain in the joints.[en.wikipedia.org]

Treatment

  • DB00747 Scopolamine For the treatment of excessive salivation, colicky abdominal pain, bradycardia, sialorrhoea, diverticulitis, irritable bowel syndrome and motion sickness. DB05855 Rivanicline Investigated for use/treatment in ulcerative colitis.[drugbank.ca]
  • The phosphoric acid treatment, however, provided a substantially higher leaf protein recovery than the acetone.[google.com]
  • Her symptoms subsided after receiving treatment in a public hospital and she was discharged on December 25. The DH conducted immediate investigation upon the notification.[info.gov.hk]
  • Vital function support, decontamination, symptomatic treatment and, in severe cases, antidote therapy with physostigmine are useful to control acute poisoning . a Department of Internal and Emergency Medicine, University of Catania, St Marta Hospital,[journals.lww.com]

Prognosis

  • Other areas of interest include identifying new biomarkers that can be used for diagnosis and prognosis of liver disease, understanding mitochondrial oxidative stress in Alzheimers disease and gastrointestinal dysfunction in autism. Dr.[books.google.com]

Epidemiology

  • Epidemiology Frequency United States Incidence is sporadic, with clusters of poisoning cases, mostly among adolescents using plants for their hallucinogenic effects.[emedicine.medscape.com]
  • Epidemiology and Social History - The plant has been described throughout history as a toxin famous for its mind altering properties. There are references to it in Homer's Odyssey and Shakespeare plays.[aacc.org]
  • Epidemiology The 2004 annual report of the American Association of Poison Control Centers listed 1058 cases of exposure to anticholinergic plants, 456 of these being intentional.[calpoison.org]
  • EPIDEMIOLOGY The plant has been described throughout history as a toxin famous for its mind-altering properties.[erowid.org]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology Tropane alkaloids competitively inhibit postsynaptic muscarinic acetylcholine receptors producing the classic anticholinergic syndrome.[calpoison.org]
  • Pathophysiology Toxicity from plants containing tropane alkaloids manifests as classic anticholinergic poisoning.[emedicine.medscape.com]

Prevention

  • Patel has edited biomedical books in the area of nutrition and health prevention, autism, biomarkers, and has published over 150 articles and in 2014 he was elected as a Fellow to The Royal Society of Chemistry.[books.google.com]
  • A CHP spokesman reminded members of the public to maintain personal, food and environmental hygiene to prevent food-borne diseases. The case involved 34 males and 25 females aged between 18 and 88.[dh.gov.hk]
  • This prevents soil-borne diseases and insect pests that overwinter in the soil from infesting the second-year crop.[homeguides.sfgate.com]
  • Adolescents often face temptations to experiment with various substances and, unfortunately, this is the time when ... read more Caregivers Should Be Screened Early, Often to Prevent Depression, Anxiety Feb. 10, 2017 — Currently, more than 34 million[sciencedaily.com]
  • PREVENTION Defoliation programs are one way to decrease access to Jimson Weed. It is important to educate health care providers about the hazards and symptoms involved with contact with Datura stramonium.[erowid.org]

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