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Solid Ovarian Teratoma


Presentation

  • An additional but far more important prognostic guide in this series was provided by extra-embryonic tissue of yolk sac origin, which was present in variable amounts and diverse histologic patterns; all teratomas including this component were fatal, frequently[ncbi.nlm.nih.gov]
  • Presents a full-color design that includes clear illustrative examples of the relevant pathology and clinical issues, for quick access to the answers you need. Incorporates the codified WHO classification for all lymphomas and leukemias.[books.google.de]
  • Considering that the initial presentation in this case was endometrial and ovarian makes the occurrence of GTS-like syndrome even more unique.[jhu.pure.elsevier.com]
  • Immature teratomas tend to be larger than mature cystic teratomas at initial presentation. Extension through the tumor capsule may be present. Immature teratoma may metastasise to the peritoneum, liver or lung.[radiopaedia.org]
  • Patients presenting with endocrine disturbances were rare in this series. Four patients (1.8%) in our series presented with endocrine disturbances.[nzma.org.nz]
Excitement
  • This exciting new, full-color reference provides you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children with cancer.[books.google.de]
Adnexal Mass
  • Thus, in clinical practice, MRI may provide further reassurance regarding the benign nature of an adnexal mass, based on its reliable diagnosis of benign adnexal masses.[dovepress.com]
  • […] of pregnant patients with adnexal masses. 30 Nonpregnant, premenopausal women with an adnexal mass most likely have a follicular cyst.[aafp.org]
  • MRI is useful for further characterization of adnexal masses, while CT is rarely indicated for primary evaluation. Links to the criteria can be found below.[stritch.luc.edu]
  • Several ovarian and/or adnexal masses have specific ultrasound features.[appliedradiology.com]
  • Definition Ovarian cysts, also known as ovarian masses or adnexal masses, are frequently found incidentally in asymptomatic women.[clevelandclinicmeded.com]

Workup

  • […] shadowing calcific or dental (tooth) components the presence of fluid-fluid levels 5 multiple thin, echogenic bands caused by the hair in the cyst cavity: the dot-dash pattern color Doppler: no internal vascularity internal vascularity requires further workup[radiopaedia.org]
  • WORKUP Lab Studies: Elevated serum alpha-fetoprotein (AFP) and beta-human chorionic gonadotropin (HCG) levels may be indicative of malignancy, as these values are within reference ranges in most patients with benign teratomas.[csh.org.tw]
  • A 17 Serum CA 125 levels should not be routinely used during the diagnostic workup of an adnexal mass in a premenopausal patient. B 20 Serum CA 125 levels should be drawn in postmenopausal patients with adnexal masses to guide treatment options.[aafp.org]
  • Although current studies have not shown a definite advantage of the three-dimensional power Doppler over two-dimensional power Doppler in accurately diagnosing ovarian malignancy, future studies my help define the role of these technologies in the workup[dovepress.com]
Ovarian Mass
  • An ovarian mass in a premenopausal girl or a post-menopausal woman is abnormal. In the reproductive age group, an ovarian mass may be malignant, but it is more likely benign.[iame.com]
  • Ovarian masses are commonly encountered during acute laparoscopy for suspected appendicitis or ovarian torsion. Best practice regarding the management of ovarian masses remains uncertain.[nzma.org.nz]
  • […] case of a pedunculated fibroid that can mimic an ovarian mass (Figure 8).[appliedradiology.com]

Treatment

  • Treatment depends on your type of germ cell tumour.[about-cancer.cancerresearchuk.org]
  • Treatment Mature cystic teratomas can be surgically removed and they don’t require any other treatment [5].[cancerwall.com]
  • Several new treatment algorithms are featured as well as an extensive summary of recommendations. Download the PDF from Annals of Oncology[esmo.org]
  • Treatment and prognosis Treatment is generally with oophorectomy, and if distant metastases are present postoperative chemotherapy.[radiopaedia.org]

Prognosis

  • It is important when considering prognosis and therapy to realize the metastatic potential of extra-embryonic elements in teratomas, as distinct from the tendency of immature embryonic components to implant locally and mature into noninvasive deposits[ncbi.nlm.nih.gov]
  • Treatment and prognosis Treatment is generally with oophorectomy, and if distant metastases are present postoperative chemotherapy.[radiopaedia.org]
  • Sarcomatous transformation is very unusual and carries a particularly grim prognosis.[omicsonline.org]
  • Stage I IT of ovary has better prognosis. Combination of surgery and chemotherapy can give longer survival even in recurrent disease.[ijpmonline.org]
  • […] gestation has an abysmal prognosis, with a 93% mortality rate.[csh.org.tw]

Etiology

  • The etiology of pneumatosis cystoides-like structures in ovarian teratomas is not clear. The first case of ovarian mature cystic teratoma with pneumatosis cystoides-like struc- tures was published in 1989 by Maudsley and Zakhour(9).[newslab.sk]
  • Changing etiologies of unexplained adult nephrotic syndrome: A comparison of renal biopsy findings from 1976-1979 and 1995-1997. Am J Kid Dis 1997;30:621-31. 20. Waldman M, Crew RJ, Valeri A, et al.[sjkdt.org]
  • Key Imaging Finding Ovarian mass with calcification and fat Differential Diagnosis Ovarian teratoma (mature and immature) Other germ cell tumors Sex cord stromal tumors Epithelial tumors Fat containing tumors Discussion Ovarian lesions are a common etiology[jaocr.org]
  • In nonpregnant patients, the most common etiologies are functional cysts and leiomyomata. 10 Adnexal masses are characterized on ultrasonography as cystic, solid, or complex.[aafp.org]
  • The frequency of autoimmune N-methyl-D-aspartate receptor encephalitis surpasses that of individual viral etiologies in young individuals enrolled in the California encephalitis project. Clin Infect Dis. 2012;54(7):899–904. 6.[medichub.ro]

Epidemiology

  • Includes all-new chapters on cytology, immunohistochemistry, flow cytometry, molecular biology, and epidemiology and biostatistics.[books.google.com]
  • Risk factors for benign, borderline and invasive mucinous ovarian tumors: epidemiological evidence of a neoplastic continuum? Gynecol Oncol 2007; 107:223–230.[clevelandclinicmeded.com]
  • Lee SD (2004) Epidemiological and clinical behavior of prepubertal testicular tumors in Korea. J Urol 172:674–678 PubMed CrossRef Google Scholar 14.[link.springer.com]
  • Epidemiology Benign ovarian tumours occur in 30% of females with regular menses (eg, luteal cysts as incidental findings on pelvic scans) and 50% of females with irregular menses.[patient.info]
  • […] female genital tract understand the concept of borderline tumors and how to distinguish them from carcinomas be able to describe clinical features including relevant associations be able to suggest possible clinical outcomes and response to treatment Epidemiology[med-ed.virginia.edu]
Sex distribution
Age distribution

Pathophysiology

  • It brings together the pathophysiology of disease with detailed clinical guidance on diagnosis and management for the full range of childhood cancers, including aspects important in optimal supportive care.[books.google.de]
  • Removal of benign cysts does not decrease future mortality from ovarian cancer. 1,3-5 Back to Top Pathophysiology Provided below is a brief description of the pathophysiology of various types of physiologic and neoplastic ovarian cysts and the potential[clevelandclinicmeded.com]
  • Pathophysiology: Teratomas are made up of a variety of parenchymal cell types representative of more than a single germ layer, usually all 3. Arising from totipotential cells, these tumors typically are midline or para-axial.[csh.org.tw]
  • Teratomas, specifically solid teratomas, are essentially devoid of organization; thus, the presence of some degree of organization, a high degree of cellular differentiation, and cystic structure differentiates dermoids from teratomas. [3] Pathophysiology[emedicine.medscape.com]

Prevention

  • Colombo, on behalf of the ESMO Guidelines Committee These updated guidelines on non-epithelial ovarian cancer cover prevention, diagnosis, treatment and follow-up for early and advanced stages and recurrences of germ cell tumours, sex cord-stromal tumours[esmo.org]
  • Back to Top Prevention and Screening Prevention Oral contraceptives may prevent new functional cysts from forming. 18-19 Oral contraceptives do not, however, hasten the resolution of preexisting cysts.[clevelandclinicmeded.com]
  • Preventive Services Task Force. Genetic risk assessment and BRCA mutation testing for breast and ovarian cancer susceptibility: systematic evidence review for the U.S.[aafp.org]
  • (By the way, if you are looking for a natural step-by-step method of preventing ovarian cysts, you should take a look at this ovarian cyst natural treatment guide. ) Dermoid ovarian cysts are a type of cystic growths that develop on or in the ovaries.[beatsofhealth.com]
  • Conclusions In order to prevent residual disease, routine checking of the contralateral ovary during surgical resection of a recurrent lesion is necessary.[bmcwomenshealth.biomedcentral.com]

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