We present three children (aged 9, 10, and 14 years) with solitary rectal ulcer syndrome that had presented with rectal bleeding. [ncbi.nlm.nih.gov]

• Asymptomatic

  Of the four patients previously reported as asymptomatic, one remained asymptomatic, one maintained marked improvement, and another slight improvement; one had reverted to pretreatment status. [ncbi.nlm.nih.gov]

• Inflammation

  Rectal biopsy under sigmoidoscopy demonstrated non-specific inflammation, without evidence of malignancy. [ncbi.nlm.nih.gov]

  inflammation could be specified, and (c) the interobserver variability in diagnosing inflammation. [thedoctorsdoctor.com]

  Lesions may include: (1) inflammation of the rectal mucosa with induration, erythema and/or edema (2) 0, 1 or multiple superficial mucosal ulcers (3) 0, 1 or multiple polypoid lesions Histologic features: (1) smooth muscle proliferation that extends from [meducator3.net]

• Swelling

  Applying granulated sugar on the exposed rectal tissue can reduce the edema (swelling). Disease Treatment: Conservative: A bulk forming agent (e.g. psyllium) or stool softener can also reduce constipation. [omicsonline.org]

  Prior polypectomy Ulcer appears up to four weeks after polypectomy Inguinal lymphogranuloma (Durand-Nicolas-Favre disease) Tropical STD (viral) Narrowing of rectal lumen Anal swelling Syphilis, primary syphilitic sore Three weeks after infection can be [rrnursingschool.biz]

  […] need to be used to induce straining. [3] The perianal skin may be macerated (softening and whitening of skin that is kept constantly wet) and show excoriation. [9] Proctoscopy/sigmoidoscopy/colonoscopy [ edit ] These may reveal congestion and edema (swelling [en.wikipedia.org]

• Perineal Pain

  His symptoms had worsened over the preceding 12 years and recently associated with perineal pain. [academic.oup.com]

• Constipation

  Most children were referred with suspected constipation, diarrhoea, or inflammatory bowel disease. [ncbi.nlm.nih.gov]

  Continue Learning about Constipation Constipation Constipation is a temporary condition characterized by infrequent bowel movements (BM), passing hard stools or straining when you do have a bowel movement. [sharecare.com]

  It is virtually impossible to be constipated and keep a sunny disposition. Follow the steps in this guide to alleviate constipation and lead a happier healthy life. Get My Free Ebook [rrnursingschool.biz]

• Rectal Bleeding

  Solitary rectal ulcer syndrome (SRUS) is an uncommon rectal disorder. Massive rectal bleeding is a rare presentation of SRUS, and can pose an endoscopic challenge in differentiating from other causes of massive rectal bleeding. [ncbi.nlm.nih.gov]

• Tenesmus

  It usually presents with rectal bleeding, constipation, mucous discharge, prolonged straining, tenesmus, and lower abdominal pain. The rectal bleeding varies from a little fresh blood to severe hemorrhage that requires blood transfusion. [ncbi.nlm.nih.gov]

• Rectal Pain

  A 15-year-old boy with Marshall-Smith syndrome presented with increased frequency and urgency of stooling, hematochezia, and rectal pain. A polypoid mass was found at the anorectal junction and excised. [ncbi.nlm.nih.gov]

  In some cases constipation can be a sign of a more serious condition, especially if you experience symptoms such as bloody stool or rectal pain. Learn more about ways to prevent and treat constipation with expert advice from Sharecare. [sharecare.com]

  Symptoms & Signs Individuals suffering from the condition may have bleeding or mucus discharge of the rectum, constipation, diarrhea, or rectal pain or anal sphincter spasms. Others may not manifest any symptoms. [signssymptoms.org]

  […] incontinence Rectal pain However, some people with solitary rectal ulcer syndrome may experience no symptoms. [mayoclinic.org]

• Blood in Stool

  RESULTS: Presenting symptoms were consistent but nonspecific, most commonly including blood in stools, diarrhea alternating with constipation, and abdominal/perianal pain. [ncbi.nlm.nih.gov]

  […] in stool Gastrointestinal bleeding Faecal occult blood Change in bowel habit Change in stool calibre Diarrhoea / loose stool Indigestion, bloatedness Irritable Bowel Syndrome (IBS) Loss of weight Anaemia Abdominal distension, vomiting Abdominal pain [practo.com]

• Erythema

  The syndrome is poorly named because associated lesions may be solitary or multiple and ulcerated or nonulcerated; they range from mucosal erythema to ulcers to small mass lesions. [msdmanuals.com]

  BACKGROUND: Solitary rectal ulcer syndrome is a rare disorder characterized by erythema or ulceration of the rectal wall, associated with typical histological features, and disturbed defaecatory behaviour with the passage of blood and mucus. [ncbi.nlm.nih.gov]

• Sweating

  A sweat test should also be done to exclude cystic fibrosis in children with rectal prolapse. [journals.lww.com]

• Behavior Disorder

  BACKGROUND: Solitary rectal ulcer syndrome (SRUS) is a behavioral disorder whose pathophysiology is incompletely understood. Likewise, its treatment, particularly the role of biofeedback therapy (BT) is unclear. [ncbi.nlm.nih.gov]

• Urinary Retention

  Complications, including infection, urinary retention, bleeding, anastomotic dehiscence (opening of the stitched edges inside), stricture (narrowing of the gut lumen), diarrhea, and fecal impaction occur in 6-32% of cases. [5] [9] Mortality occurs in [en.wikipedia.org]

• Confusion

  BACKGROUND: Although the clinicopathologic features of solitary rectal ulcer syndrome (SRUS) are well documented, the heterogeneous endoscopic appearance of lesions that the syndrome produces and its rare incidence may make for clinical confusion. [ncbi.nlm.nih.gov]

  It can be easily confused with prolapsed (3rd or 4th degree) hemorrhoids. Solitary rectal ulcer syndrome (SRUS, solitary rectal ulcer, SRU) occurs with internal rectal intussusception and is part of the spectrum of rectal prolapse conditions. [manchestergeneralandcolorectalsurgery.co.uk]

• Irritability

  Alterations of brain activity associated with resolution of emotional distress and pain in a case of severe irritable bowel syndrome. Gastroenterology, 124(3), 754-761. doi:10.1053/gast.2003.50103 [doi];S0016508502159816 [pii]. [ijbmc.org]

  Constipation Prescription Did you ever think feeling angry and irritable could be a symptom of constipation? A horrible fullness and pressing sharp pains against the bladders can’t help but affect your mood. [rrnursingschool.biz]

  Asian consensus on irritable bowel syndrome. J Gastroenterol Hepatol 2010;25:1189-1205. Felt-Bersma RJ, Cuesta MA. Rectal prolapse, rectal intussusception, rectocele, and solitary rectal ulcer syndrome. Gastroenterol Clin North Am 2001;30:199-222. [jnmjournal.org]

  Sucralfate enemas contain an aluminum salt and work by coating the ulcer and creating a barrier against irritants, allowing the ulcer to heal. Corticosteroid enemas may also help decrease inflammation and aid ulcer healing. Biofeedback. [knowyourdisease.com]

  Surgery Cancer screening Endorectal Ultrasonography with 3D Reconstruction Fistulotomy Fistulotomyendoanal Ultrasonography with 3D Reconstruction Artificial Bowel Sphincter Implantation Anal Manometry Evaluation Defecating Proctogram bedah colorectal Irritable [practo.com]

Data recorded included: patient's age, gender, clinical presentation, past surgical history, diagnostic and preoperative workup, operative procedure, complications, and outcomes. [ncbi.nlm.nih.gov]

• Microcytic Anemia

  Features of microcytic anemia with low values of hemoglobin, hematocrit and mean corpuscular volume may, however, be seen in a child with a history of recurrent bleeding per rectum. [journals.lww.com]

  Features of microcytic anemia with low values of hemoglobin, hematocrit and mean corpuscular volume may, however, be seen in a child with a history of recurrent bleeding per rectum[ 35 ]. [wjgnet.com]

• Polyps

  Associated underlying conditions were hemorrhoids in 7 (6%), hyperplastic polyps in 4 (3.5%), adenomatous polyps in 2(2%), history of ulcerative colitis in 3 (2.5%) while adenocarcinoma of colon was observed in two patients. [ncbi.nlm.nih.gov]

  The appearances may be confused with an inflammatory polyp, hyperplastic polyps or rectal carcinoma resulting in a delay of diagnosis and treatment [ 10 ]. [academic.oup.com]

• Multiple Ulcerations

  Rectal ulceration was the most common endoscopic finding, being seen in 9 of the 3 cases; 3 of these cases had multiple ulcerations. Two patients had rectal polyps, with one of them having multiple polyps. [ncbi.nlm.nih.gov]

  Defecography showed 18 cases (16.6%) of solitary ulcer, 1 case (3.7%) of multiple ulcers and 2 cases (7.4%) of granular proctitis ; but it missed 3 cases (11.1%) of small solitary ulcer, 2 cases (7.4%) of small multiple ulcers, and 1 case (3.7%) of pseudopolyp [pesquisa.bvsalud.org]

• Ischemic Changes

  The underlying etiology is not well understood, but it is secondary to ischemic changes and trauma in the rectum associated with paradoxical contraction of the pelvic floor and the external anal sphincter muscles; rectal prolapse has also been implicated [ncbi.nlm.nih.gov]

  The underlying etiology is not well understood, but it is secondary to ischemic changes and trauma in the rectum associated with paradoxical contraction of the pelvic floor and the external anal sphincter muscles; rectal prolapse has also been implicate [scinapse.io]

  This may lead to venous congestion, poor blood flow and edema in the mucosal lining of rectum and ischemic changes with resultant ulceration. [journals.lww.com]

  The lesion is thought to arise from ischemic changes in the bowel resulting in repeated ulceration with healing and subsequent re-injury. [thedoctorsdoctor.com]

  This may lead to venous congestion, poor blood flow, and edema in the mucosal lining of the rectum and ischemic changes with resultant ulceration. [wjgnet.com]

In this review, we discuss current diagnosis and treatment for SRUS. [ncbi.nlm.nih.gov]

In these cases there are more therapeutic possibilities and the prognosis is slightly better. There is no method of choice for SRUS treatment and the prognosis is hard to predict. [omicsonline.org]

Prognosis was largely dependent on accurate diagnosis and management of the underlying disorders. [thedoctorsdoctor.com]

Rectal Ulcer Syndrome from other Diseases The differential diagnosis of SRUS (and CCP) includes: polyps endometriosis inflammatory granulomas infectious disorders drug-induced colitis mucus-producing adenocarcinoma Natural History, Complications and Prognosis [wikidoc.org]

The prognosis with this type is poor. Sudden death can occur after visceral perforation or after the rupture of a large vessel, most commonly an abdominal and splenic vessel. [emedicine.medscape.com]

[…] bowel reversing retrieval., Hara M, Takayama S, Sato M, Imafuji H, Takahashi H, Takeyama H, Surgical laparoscopy, endoscopy & percutaneous techniques, 21, (5) e235 - 8, 10, Refereed Isolated tumor cell in lateral lymph node has no influences on the prognosis [nrd.nagoya-cu.ac.jp]

Its etiology is unknown but it seems related to excessive straining with defecation. Prolonged efforts force the anterior rectal mucosa into the anal canal with strangulation and appearance of congestion, edema, and ulceration. [ncbi.nlm.nih.gov]

[…] since not necessarily solitary, ulcerated or rectal) Epidemiology Uncommon (incidence of 1 per 100,000 per year) Usually third and fourth decade More common in women Rarely in children ( Pediatrics 2002;110:e79 ) Sites Usually in rectosigmoid colon Etiology [pathologyoutlines.com]

The etiology and exact pathogenesis of this condition are poorly understood. [scinapse.io]

Definition / general Solitary or multiple ulcerated or polypoid lesions 4 - 10 cm from anal margin Terminology Also called mucosal prolapse syndrome (may be a better term since not necessarily solitary, ulcerated or rectal) Epidemiology Uncommon (incidence [pathologyoutlines.com]

Epidemiology Typically younger patients - average age of presentation ~30 years in one study. [3] Rare. Clinical presentation Usually presents as BRBPR ~ 85% of cases. [3] Abdominal pain present in approx. 1/3. [3] May be very painful. [librepathology.org]

Epidemiology and Demographics The condition is thought to be uncommon. It usually occurs in young adults, but children can be affected too. [1] Causes The essential cause of SRUS is thought to be related to too much straining during defecation. [wikidoc.org]

Epidemiology Frequency The prevalence of Ehlers-Danlos syndrome (EDS) is reported to be 1 case in approximately 400,000 people, but mild or incomplete forms appear to be underdiagnosed and more common than other forms. [emedicine.medscape.com]

The aim of the present review is to summarize the clinical features, pathophysiology, diagnostic methods and treatment strategies associated with SRUS. [ncbi.nlm.nih.gov]

Solitary rectal ulcer syndrome: Clinical features, pathophysiology, diagnosis and treatment strategies. [wjgnet.com]

Learn more about ways to prevent and treat constipation with expert advice from Sharecare. More Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. [sharecare.com]

Stool bulking agents and biofeedback constipation management to prevent paradoxical puborectalis contraction. Topical corticosteroids, salicylates, sucralfate enemas, and biofeedback has been described but experience is limited. [gastroenterologybook.com]

CONCLUSIONS: Double contrast barium enema represents a useful radiologic method to diagnose solitary rectal ulcer, but air insufflation and pharmacological hypotonia prevent the functional study of rectal walls. [pesquisa.bvsalud.org]

The indications for colonoscopy are myriad, while screening and cancer prevention are becoming the most frequent indication for this examination. [gastrohep.com]

If you don't have any symptoms or your symptoms are mild, treating and preventing constipation, such as by increasing fiber and fluid intake, may improve symptoms and heal the ulcer. [knowyourdisease.com]