The authors present a case of a 59-year-old man presenting with Brown-Sequard syndrome and in whom metastatic lung adenocarcinoma to the spinal cord was subsequently discovered. [ncbi.nlm.nih.gov]

An abstract of this case report was presented as a poster board presentation at the 2016 Academy of Academic Physiatrists annual meeting in Sacramento, California. [journals.lww.com]

• Lower Extremity Pain

  Case report This 59-year-old woman presented with a 2-month history of low back pain and right lower extremity pain. [nature.com]

• Unable to Stand

  Five days later, he was unable to stand or to void urine. A lung cancer was found in the right upper lobe. A spinal cord metastasis from the lung cancer was suspected from the neurologic and pulmonary findings. [ncbi.nlm.nih.gov]

• Familial Adenomatous Polyposis

  adenomatous polyposis.[ 15 ] Honma et al .[ 16 ] reported a case of intramedullary metastasis of presumed poorly differentiated thyroid carcinoma associated with a haemorrhage caudal to the tumour, which was identical to the configuration demonstrated [surgicalneurologyint.com]

• Fecal Incontinence

  He presented with new-onset saddle anesthesia and fecal incontinence. Magnetic resonance imaging demonstrated a spindle-shaped intramedullary lesion of the conus medullaris. [jmedicalcasereports.biomedcentral.com]

  He denies back pain or urinary or fecal incontinence. Regarding pain management, he had been recently treated at one of the pain clinics in the hospital and has continued on opioid medication at another institution. [mdedge.com]

• Back Pain

  She received abdominal ovariectomy for the ovarian adenocarcinoma 4 years before she suffered from back pain and showed neurological symptoms. The thoracic intramedullary lesion was confirmed by preoperative magnetic resonance imaging. [ncbi.nlm.nih.gov]

  He denies back pain or urinary or fecal incontinence. Regarding pain management, he had been recently treated at one of the pain clinics in the hospital and has continued on opioid medication at another institution. [mdedge.com]

• Low Back Pain

  Case report This 59-year-old woman presented with a 2-month history of low back pain and right lower extremity pain. [nature.com]

  back pain, it is the most common systemic disease affecting the spine.17 An important clinical inquiry is to determine whether back pain in an established cancer patient can be ruled out without extensive imaging. [mdedge.com]

  Lipani treats many other spinal conditions such as spinal stenosis, herniated discs, degenerative disc disease, low back pain, neck pain, spinal tumors, spinal cancer and more. Dr. [princetonneurologicalsurgery.com]

  back pain over the past 6 months. [orthobullets.com]

  CASE REPORT A 54-year-old male presented with bilateral low back pain, tingling, numbness, and weakness in both the lower limbs, and incontinence of the bowel and bladder of 2-months duration [ Figure 1 ]. [surgicalneurologyint.com]

• Spine Pain

  A month later, the patient a rebel cervical spine pain and a heaviness of the upper limbs, in front of which a cerebro-cervical magnetic resonance imaging (MRI) was requested objectifying a right hypopharyngeal process, suspicious right internal jugular [panafrican-med-journal.com]

• Hyperreflexia

  Pyramidal signs such as hyperreflexia, spasticity, Babinski sign, and clonus can be found. 18 Lesions at the level of the conus medullaris (L1-L2) usually result in flaccid paresis and early sphincter involvement, while lesions below this level (cauda [healio.com]

• Focal Neurological Deficit

  He had full reversal of his pain and sensory deficit, and remained ambulatory without any focal neurological deficit. [ncbi.nlm.nih.gov]

• Spinal Cord Syndrome

  Abstract Intramedullary spinal cord metastases are rarely the presenting manifestation of a previously undiagnosed neoplasms. We report such a case in which a subacutely progressive motor and sensory spinal cord syndrome was the initial problem. [ncbi.nlm.nih.gov]

• Urinary Incontinence

  On admission, she had difficulty with her gait and with urinary retention and had episodes of overflow urinary incontinence. Her midthoracic pain was incapacitating despite a transdermal fentanyl patch and oral rescue opioids. [jamaevidence.mhmedical.com]

  Neurol India 2013;61:444-6 Sir, A 74-year-old man presented with a 2-week history of decreased sensation and weakness of bilateral lower extremities along with urinary incontinence. [neurologyindia.com]

[…] night pain may be mechanical pain due to bone destruction or tumorigenic pain which often occurs at night metastatic hypercalcemia Physical exam neurologic deficits caused by compression of the spinal cord with metastatic disease to the spine Evaluation Workup [orthobullets.com]

• Ground Glass Appearance

  Pathology H and E (hematoxylin and eosin) staining showed neoplastic tissue composed of sheaths of cells with ovaloid nuclei and without a cytoplasmic border; some had a ground glass appearance and nuclear grooves. [surgicalneurologyint.com]

• Prostatic Lesion

  It also seems reasonable to use SRS for lesions, such as prostate lesions, that respond poorly to conventional radiation and are shown to respond well to SRS in the brain [ 10 ]. [jmedicalcasereports.biomedcentral.com]

• White Matter Lesions

  We present a case of a 44 year-old male with a history of parotid gland metastatic salivary ductal carcinoma (SDC) and incidental demyelinating white matter lesions on brain magnetic resonance imaging (MRI) diagnosed as radiologically isolated syndrome [ncbi.nlm.nih.gov]

Median survival ranged from 3.8 to 11.6 months after treatment in patients who were deceased at time of publication. Treatments included corticosteroids, chemotherapy, various radiotherapies, and surgical resection. [ncbi.nlm.nih.gov]

Abstract Intramedullary spinal cord metastases are uncommon in Hodgkin's disease and have a poor prognosis. [ncbi.nlm.nih.gov]

Numb chin syndrome in cancer patients: etiology, response to treatment, and prognostic significance. Neurology. 1992;42:1181–4. Copyright © 1999 by the American Academy of Family Physicians. This content is owned by the AAFP. [aafp.org]

Although PTC is the most common histological type of thyroid malignancy with an increasing incidence in many countries, its involvement as an etiology for IMSCM is rare. [surgicalneurologyint.com]

Despite more common etiologies of squamous cell carcinoma, this case report highlights the importance of being mindful of rare diseases. Statement of Ethics The authors have no ethical conflicts to disclose. [karger.com]

The epidemiology, pathogenesis, clinical presentation, diagnostic considerations, and therapeutic options are discussed. [ncbi.nlm.nih.gov]

The worldwide epidemiology of prostate cancer: Perspectives from autopsy studies. Can J Urol 2008;15:3866-71. [ PUBMED ] 5. Lieberson RE, Veeravagu A, Eckermann JM, Doty JR, Jiang B, Andrews R, et al. [neurologyindia.com]

PubMed | Google Scholar National Cancer Institute Surveillance Epidemiology and End Results, SEER Stat Fact Sheet: Larynx cancer http://seer.cancer.gov/statfacts/html/laryn.html. Accessed on 27 December 2016. [panafrican-med-journal.com]

Generally speaking, any cancer patient who presents with new or worsening back pain—even in the absence of neurological deficits—merits evaluation for spinal cord compression.6 Nevertheless, individual risk assessment is warranted.7 Epidemiology In the [mdedge.com]

There is a need for improving awareness among all clinicians so as to make prompt diagnosis and referral of MSCC a reality. 2 EPIDEMIOLOGY AND AETIOLOGY Bone is the third most common site of metastases after the liver and the lung. [bjgp.org]

The first classifies the wide variety of disorders that can cause neurologic symptoms the patient with cancer, discusses the pathophysiology of nervous system metastases, the pathophysiology and treatment of brain edema and the approach to supportive [books.google.com]

Give steroids Pathophysiology Spinal Cord tumors can arise via a number of different sources including both intramedullary and extramedullary tumors. Primary tumors include neuron cell tumors, glial cell tumors, and meningeal tumors. [lasvegasemr.com]

Multiple spinal epidural metastases were noted in 31% of those who underwent complete imaging of the spine.12 Pathophysiology Most cases of MSCC are epidural in origin, arising from the vertebral column in 85% of patients.8 Epidural spread is caused mainly [mdedge.com]

Pathophysiology Spread from primary tumors is mainly by the arterial route. Retrograde spread through the Batson plexus during Valsalva maneuver is postulated. Direct invasion through the intervertebral foramina can also occur. [emedicine.medscape.com]

Skeletal complications of Gaucher disease: pathophysiology, evaluation, and treatment. Semin Hematol 1995; 32(3 suppl 1):20–27 Google Scholar Patten RM, Shuman WP, Teefey S. [link.springer.com]

Surgical treatment prevented further neurological deterioration. This is the first case report of ISCM from pNET. [ncbi.nlm.nih.gov]

Objectives: To investigate the correct positioning and examine the effects of spinal bracing to relieve pain or to prevent further vertebral collapse in patients with MSCC. [cochrane.org]

The physician who promptly recognizes neurologic symptoms occurring in a patient with cancer and makes an early diagnosis may prevent the symptoms from becoming permanently disabling or sometimes lethal. [books.google.com]

This will not only treat the patient’s symptoms but prevent further bony destruction of the vertebrae, avoid open surgery, prevent neurologic dysfunction and preserve quality of life. [princetonneurologicalsurgery.com]

It both reduces the pain for 90% of patients, and can prevent spinal cord compression, fractures, and recurrences. [brainmetsbc.org]