Presentation
The authors present a case of a 59-year-old man presenting with Brown-Sequard syndrome and in whom metastatic lung adenocarcinoma to the spinal cord was subsequently discovered. [ncbi.nlm.nih.gov]
Hematological
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Spontaneous Hemorrhage
The occurrence of metastatic lesions with hemorrhage arising from a PTC are extremely rare.[ 5 ] Spontaneous hemorrhage was presumably responsible for the acute progress of myelopathy in our patient. [surgicalneurologyint.com]
Entire Body System
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Lower Extremity Pain
Case report This 59-year-old woman presented with a 2-month history of low back pain and right lower extremity pain. [nature.com]
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Unable to Stand
Five days later, he was unable to stand or to void urine. A lung cancer was found in the right upper lobe. A spinal cord metastasis from the lung cancer was suspected from the neurologic and pulmonary findings. [ncbi.nlm.nih.gov]
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Familial Adenomatous Polyposis
adenomatous polyposis.[ 15 ] Honma et al .[ 16 ] reported a case of intramedullary metastasis of presumed poorly differentiated thyroid carcinoma associated with a haemorrhage caudal to the tumour, which was identical to the configuration demonstrated [surgicalneurologyint.com]
Gastrointestinal
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Fecal Incontinence
He presented with new-onset saddle anesthesia and fecal incontinence. Magnetic resonance imaging demonstrated a spindle-shaped intramedullary lesion of the conus medullaris. [jmedicalcasereports.biomedcentral.com]
He denies back pain or urinary or fecal incontinence. Regarding pain management, he had been recently treated at one of the pain clinics in the hospital and has continued on opioid medication at another institution. [mdedge.com]
Musculoskeletal
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Back Pain
She received abdominal ovariectomy for the ovarian adenocarcinoma 4 years before she suffered from back pain and showed neurological symptoms. The thoracic intramedullary lesion was confirmed by preoperative magnetic resonance imaging. [ncbi.nlm.nih.gov]
Case report This 59-year-old woman presented with a 2-month history of low back pain and right lower extremity pain. [nature.com]
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Low Back Pain
Case report This 59-year-old woman presented with a 2-month history of low back pain and right lower extremity pain. [nature.com]
CASE REPORT A 54-year-old male presented with bilateral low back pain, tingling, numbness, and weakness in both the lower limbs, and incontinence of the bowel and bladder of 2-months duration [ Figure 1 ]. [surgicalneurologyint.com]
back pain, it is the most common systemic disease affecting the spine.17 An important clinical inquiry is to determine whether back pain in an established cancer patient can be ruled out without extensive imaging. [mdedge.com]
Lipani treats many other spinal conditions such as spinal stenosis, herniated discs, degenerative disc disease, low back pain, neck pain, spinal tumors, spinal cancer and more. Dr. [princetonneurologicalsurgery.com]
back pain over the past 6 months. [orthobullets.com]
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Spine Pain
A month later, the patient a rebel cervical spine pain and a heaviness of the upper limbs, in front of which a cerebro-cervical magnetic resonance imaging (MRI) was requested objectifying a right hypopharyngeal process, suspicious right internal jugular [panafrican-med-journal.com]
Urogenital
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Urinary Incontinence
On admission, she had difficulty with her gait and with urinary retention and had episodes of overflow urinary incontinence. Her midthoracic pain was incapacitating despite a transdermal fentanyl patch and oral rescue opioids. [jamaevidence.mhmedical.com]
Neurologic
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Hyperreflexia
Pyramidal signs such as hyperreflexia, spasticity, Babinski sign, and clonus can be found. 18 Lesions at the level of the conus medullaris (L1-L2) usually result in flaccid paresis and early sphincter involvement, while lesions below this level (cauda [healio.com]
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Focal Neurologic Deficit
He had full reversal of his pain and sensory deficit, and remained ambulatory without any focal neurological deficit. [ncbi.nlm.nih.gov]
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Spinal Cord Syndrome
We report such a case in which a subacutely progressive motor and sensory spinal cord syndrome was the initial problem. The differential diagnosis and the difficulties in distinguishing intramedullary from extramedullary mass lesions are discussed. [ncbi.nlm.nih.gov]
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Excitement
T1-weighted (450/14/2 [repetition time/echo time/excitations]) sagittal spin-echo images with a 4 mm section thickness were obtained before and after an intravenous injection of gadolinium. [nature.com]
Workup
[…] night pain may be mechanical pain due to bone destruction or tumorigenic pain which often occurs at night metastatic hypercalcemia Physical exam neurologic deficits caused by compression of the spinal cord with metastatic disease to the spine Evaluation Workup [orthobullets.com]
X-Ray
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Ground Glass Appearance
Pathology H and E (hematoxylin and eosin) staining showed neoplastic tissue composed of sheaths of cells with ovaloid nuclei and without a cytoplasmic border; some had a ground glass appearance and nuclear grooves. [surgicalneurologyint.com]
Ultrasound
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Prostatic Lesion
It also seems reasonable to use SRS for lesions, such as prostate lesions, that respond poorly to conventional radiation and are shown to respond well to SRS in the brain [ 10 ]. [jmedicalcasereports.biomedcentral.com]
Other Pathologies
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White Matter Lesions
We present a case of a 44 year-old male with a history of parotid gland metastatic salivary ductal carcinoma (SDC) and incidental demyelinating white matter lesions on brain magnetic resonance imaging (MRI) diagnosed as radiologically isolated syndrome [ncbi.nlm.nih.gov]
Treatment
Median survival ranged from 3.8 to 11.6 months after treatment in patients who were deceased at time of publication. Treatments included corticosteroids, chemotherapy, various radiotherapies, and surgical resection. [ncbi.nlm.nih.gov]
Prognosis
Abstract Intramedullary spinal cord metastases are uncommon in Hodgkin's disease and have a poor prognosis. [ncbi.nlm.nih.gov]
Etiology
Although PTC is the most common histological type of thyroid malignancy with an increasing incidence in many countries, its involvement as an etiology for IMSCM is rare. [surgicalneurologyint.com]
Numb chin syndrome in cancer patients: etiology, response to treatment, and prognostic significance. Neurology. 1992;42:1181–4. Copyright 1999 by the American Academy of Family Physicians. This content is owned by the AAFP. [aafp.org]
Despite more common etiologies of squamous cell carcinoma, this case report highlights the importance of being mindful of rare diseases. Statement of Ethics The authors have no ethical conflicts to disclose. [karger.com]
Epidemiology
The epidemiology, pathogenesis, clinical presentation, diagnostic considerations, and therapeutic options are discussed. [ncbi.nlm.nih.gov]
PubMed Google Scholar National Cancer Institute Surveillance Epidemiology and End Results, SEER Stat Fact Sheet: Larynx cancer . Accessed on 27 December 2016. Google Scholar Dagli M1, Acar A, Eryilmaz A, Göçer C. [panafrican-med-journal.com]
Department of Neurosurgery, Robert C and Jeannette Powell Professor in the Neurosciences, Stanford University, 300 Pasteur Drive, Room R-225, Stanford, CA 94305, USA References Haas GP, Delongchamps N, Brawley OW, Wang CY, de la Roza G: The worldwide epidemiology [jmedicalcasereports.biomedcentral.com]
Generally speaking, any cancer patient who presents with new or worsening back pain—even in the absence of neurological deficits—merits evaluation for spinal cord compression.6 Nevertheless, individual risk assessment is warranted.7 Epidemiology In the [mdedge.com]
There is a need for improving awareness among all clinicians so as to make prompt diagnosis and referral of MSCC a reality. 2 EPIDEMIOLOGY AND AETIOLOGY Bone is the third most common site of metastases after the liver and the lung. [bjgp.org]
Pathophysiology
The first classifies the wide variety of disorders that can cause neurologic symptoms the patient with cancer, discusses the pathophysiology of nervous system metastases, the pathophysiology and treatment of brain edema and the approach to supportive [books.google.com]
Give steroids Pathophysiology Spinal Cord tumors can arise via a number of different sources including both intramedullary and extramedullary tumors. Primary tumors include neuron cell tumors, glial cell tumors, and meningeal tumors. [lasvegasemr.com]
Multiple spinal epidural metastases were noted in 31% of those who underwent complete imaging of the spine.12 Pathophysiology Most cases of MSCC are epidural in origin, arising from the vertebral column in 85% of patients.8 Epidural spread is caused mainly [mdedge.com]
Pathophysiology Spread from primary tumors is mainly by the arterial route. Retrograde spread through the Batson plexus during Valsalva maneuver is postulated. Direct invasion through the intervertebral foramina can also occur. [emedicine.medscape.com]
Skeletal complications of Gaucher disease: pathophysiology, evaluation, and treatment. Semin Hematol 1995; 32(3 suppl 1):20–27 Google Scholar Patten RM, Shuman WP, Teefey S. [link.springer.com]
Prevention
Surgical treatment prevented further neurological deterioration. This is the first case report of ISCM from pNET. [ncbi.nlm.nih.gov]
The physician who promptly recognizes neurologic symptoms occurring in a patient with cancer and makes an early diagnosis may prevent the symptoms from becoming permanently disabling or sometimes lethal. [books.google.com]
Objectives: To investigate the correct positioning and examine the effects of spinal bracing to relieve pain or to prevent further vertebral collapse in patients with MSCC. [cochrane.org]
This will not only treat the patient’s symptoms but prevent further bony destruction of the vertebrae, avoid open surgery, prevent neurologic dysfunction and preserve quality of life. [princetonneurologicalsurgery.com]
It both reduces the pain for 90% of patients, and can prevent spinal cord compression, fractures, and recurrences. [brainmetsbc.org]