Presentation
Each chapter is dual authored by a radiation oncologist and a surgeon, giving a balanced presentation of clinical scenarios. Issues of basic science and physics are also covered, and a notable chapter on normal tissue tolerance is included. [books.google.de]
Prognosis for neurological deficit depends on the magnitude of the spinal cord damage present at the onset. [patient.info]
Conclusions: The present study subtantiates the occurence of early, primary inflammatory vascular changes during the so-called latency period after irradiation without manifestation of neurological impairment. [karger.com]
This approach should not be considered at present TBI: The use of TBI as a conditioning regimen prior to high-dose chemotherapy and hematopoietic stem cell transplantation for patients with poor-risk disease 18. [slideshare.net]
The study will be featured in a press briefing today and presented at the 2017 American Society of Clinical Oncology (ASCO) Annual Meeting. [asco.org]
Entire Body System
- Hyperthermia
Several neurologic side effects have been reported previously with total-body hyperthermia — most commonly peripheral neuropathy, but not myelopathy. 1 2 3 The mechanism of action of hyperthermia in cancer. .. [nejm.org]
A Mukhopadhaya, J Mendecki, X Dong, L Liu, S Kalnicki, M Garg, A Alfieri, C Guha: “ Localized Hyperthermia Combined with Intratumoral Dendritic Cells Induces Systemic Antitumor Immunity”. Cancer Res. 2007 Aug 15;67(16):7798-806. 10. [einstein.yu.edu]
- Hodgkin Lymphoma
There is an increased risk of lung cancer after radiation treatment to the chest for Hodgkin lymphoma, especially in patients who smoke. Stomach, liver, or colorectal cancer. [cancer.gov]
Patient outcomes at the UF Health Proton Therapy center are also outstanding, showing favorable results in recent Hodgkin lymphoma, prostate and pediatric cancer post-treatment studies. Back to Top Q. [floridaproton.org]
- Movement Disorder
Movement disorders that affect the legs and eyes or the ability to speak and swallow. Nerve damage in the hands or feet. Stroke. [cancer.gov]
Respiratoric
- Hoarseness
EYE None Asymptomatic cataract Minor corneal ulceration or keratitis Symptomatic cataract Moderate corneal ulceration Minor retinopathy or glaucoma Severe keratitis Severe retinopathy or detachment Severe glaucoma Panopthalmitis/ Blindness LARYNX None Hoarseness [rtog.org]
Hoarse voice. Puffy face. Muscle and joint aches and stiffness. Constipation. Menstrual periods that are heavier than normal. Weight gain for no known reason. Depression or trouble with memory or being able to concentrate. [cancer.gov]
Cardiovascular
- Thrombosis
[…] failure, or serious and inadequately controlled cardiac arrhythmia No known bleeding diathesis or coagulopathy No prior arterial thromboembolic events, including transient ischemic attacks orcerebrovascular accidents No prior diagnosis of a deep venous thrombosis [clinicaltrials.gov]
- Decompression Sickness
Laden (26) points out that the patients assigned to the control group had a risk for developing decompression sickness with the gas mix they breathed (9% oxygen and 91% nitrogen) at 2.4 ATA. [uhms.org]
Psychiatrical
- Withdrawn
Typically, it only occurs after having taken the medication for some duration, and then stopped or withdrawn rapidly or after administering reduced dose. [en.wikipedia.org]
Workup
The diagnosis of RILP is essentially one of exclusion, metastasis or a local tumor progression with secondary nerve involvement usually leads the differential diagnosis, the minimal workup must include cerebrospinal fluid analysis, electromyography, and [gynoncrp.biomedcentral.com]
X-Ray
- Pericardial Effusion
effusion Constrictive pericarditis Moderate heart failure Cardiac enlargement EKG abnormalities Tamponade/ Severe heart failure/ Severe constrictive pericarditis ESOPHAGUS None Mild fibrosis Slight difficulty in swallowing solids No pain on swallowing [rtog.org]
Treatment
Treatment fields for the protocol conformal plans were arranged so that the maximum cord dose was not to exceed 50 Gy. Dose-volume histograms for both types of planned treatments were analyzed. [ncbi.nlm.nih.gov]
Radiation from these treatments sometimes damages the nervous system, despite the best efforts to prevent damage. [merckmanuals.com]
This type of treatment is given by a doctor called a radiation oncologist. [cancer.org]
Features a full-color design throughout and over 700 color figures which clearly depict treatment techniques; this allows for more complete integration of text, tables, and figures thus making key information easier to locate.Adds a "Diagnostic Algorithm [books.google.de]
Receiving treatment People receive proton therapy in a special treatment room. For each treatment, a member of the health care team will place the person into the device on the treatment table in the room. [cancer.net]
Prognosis
Prognosis The spinal cord has very limited powers of regeneration. Prognosis for neurological deficit depends on the magnitude of the spinal cord damage present at the onset. [patient.info]
• An analysis of the degree of necrosis in the excised tumor can permit refinements in the estimate of prognosis • In the skeletally immature child, resection may be associated with less morbidity than radiation, which can retard bone growth and cause [slideshare.net]
Your doctor will determine and discuss with you the details of your prognosis and the possible benefits of proton therapy as an addition to your treatment plan. Back to Top Q. [floridaproton.org]
Etiology
He has demonstrated that infection is not the primary etiology of mandibular necrosis by obtaining deep cultures of affected bone and showing the absence of bacteria. [uhms.org]
A much greater risk of a second malignancy is posed by the same etiologic and genetic mechanisms that are responsible for the primary tumor. [emedicine.medscape.com]
Cancer is a multigenic and multicellular disease that can arise from all cell types and organs with a multi-factorial etiology. [medsci.org]
Pathophysiology
The pathophysiological mechanisms are not yet fully understood. Diagnosis of radiation myelopathy in women with gynecologic malignancies may increase with the use of concomitant chemo-radiation. [gynoncrp.biomedcentral.com]
He has provided several key principles in the understanding of the pathophysiology of mandibular necrosis. [uhms.org]
Prevention
Radiation from these treatments sometimes damages the nervous system, despite the best efforts to prevent damage. [merckmanuals.com]
We observed that localized irradiation of the unilaterally transected adult rat spinal cord when delivered during a defined time-window (third week) postinjury prevented cavitation, enabled establishment of structural integrity, and resulted in regrowth [pnas.org]
Study Limitations and Next Steps “Longer radiation may be more effective for preventing regrowth of metastases in the spine than single-dose radiation. [asco.org]
Rapid diagnosis and management are essential to have the highest chances of preventing permanent loss of function. [patient.info]
The isocentre will be midline and anterior to the equator of the orbit to prevent divergence into the contralateral eye. [ozradonc.wikidot.com]