Compared with patients who had MS, patients who had DNMO had a poor prognosis, higher age at onset, and a more sever clinical course. DNMO was most like to affect female patients. Corticosteroids are not helpful in DNMO, and the prognosis is poor. [radiologykey.com]

This is an essential but neglected issue in modeling clinical trauma, where lesions are typically extensive. [grantome.com]

Neglect-associated fatal Marchiafava-Bignami disease in a non-alcoholic woman. Int J Legal Med 2001;115:90-93. Maki N, Hokoishi K, Komori K, Tanabe H. [A case of Marchiafava-Bignami disease caused by anorexia nervosa.] No To Shinkei 2001;53:669-671. [journal.biolpsychiatry.or.kr]

As dementia progresses, language ability may begin to deteriorate and the individual may neglect to care for himself appropriately. [britannica.com]

The most common SMDs were tonic spasms (28), new-onset RLS (23), paroxysmal focal dystonia (9), spinal myoclonus (9), subjective fasciculations (9), spontaneous clonus (8), pseudoathetosis (7), spinal tremor (6), and hyperkeplexia (3). [mdsabstracts.org]

This pattern is almost pathognomonic of cord compression because of cervical spondylosis at the C5-C6 interspace. 12 Ankle clonus and Babinski's sign (pathologic extension of the great toe elicited by stroking the foot) in the feet may also be revealed [aafp.org]

The most common SMDs were tonic spasms (28), new-onset RLS (23), paroxysmal focal dystonia (9), spinal myoclonus (9), subjective fasciculations (9), spontaneous clonus (8), pseudoathetosis (7), spinal tremor (6), and hyperkeplexia (3). [mdsabstracts.org]

Myoclonus Brief, involuntary jerks of the trunk and of the limbs may occur in spinal myoclonus. [britannica.com]

Tidal volume and mean inspiratory flow (VT/TI) tended to be reduced in EtBr rats during hypercapnia/hypoxia (p 0.06 and 0.07, respectively). [fasebj.org]

Register Spinal Cord and Optic Nerve Demyelination in Experimental Herpes Simplex Virus Type 2 Infection - 24 Hours access EUR 36.00 GBP 28.00 USD 45.00 Rental This article is also available for rental through DeepDyve. [academic.oup.com]

The spinal cord lesions showed obvious loss of myelinated nerve fibers and fibrillary gliosis with minimal inflammatory cell infiltration. [springerlink.com]

With time, gliosis develops, and plaques reach a burned-out stage consisting of demyelinated axons traversing glial scar tissue (inactive plaque). Remaining oligodendrocytes attempt to make new myelin. [neuropathology-web.org]

Its imaging manifestations are worse than its clinical ones, possibly because early gliosis does not damage normal tissue. Hormone treatment has a poor effect on gliomas. [nrronline.org]