We present 2 cases of this condition with a description of MR imaging findings. [ajnr.org]

A diagnosis of HSP was subsequently shown to be the initial presentation of ANCA-related systemic vasculitis. [ncbi.nlm.nih.gov]

CASE REPORT In February 2003, a 67-year-old man presented with a 4-month history of progressive lower-limb weakness and a 3-month history of disturbances to his hand movements and gait. On presentation, he was unable to walk. [yumpu.com]

• Walking with a Cane

  At the 3-month follow-up, the patient was able to walk with a cane. The affected site showed no remission on MRI despite continuous steroid therapy. At the 2-year follow-up, the patient could walk independently. [ncbi.nlm.nih.gov]

  At the 3-month follow-up, the patient was able to walk with a cane, neck rigidity vanished, dysphagia and limb spasticity improved. Antitubercular treatment continued for 15 months. At present, she can walk independently with some spasticity. [surgicalneurologyint.com]

• Upper Abdominal Pain

  RESULTS: We report a 66-year-old male with a history of renal cell carcinoma and bladder cancer who presented with upper abdominal pain, thoracic myelopathy (progressive weakness and numbness of the lower extremities, and gait disturbances), and weight [ncbi.nlm.nih.gov]

• Urinary Retention

  The patient suffered from progressive mild thoracic backache followed by truncal and lower extremity weakness, numbness and urinary retention. The diagnosis was confirmed by magnetic resonance (MR) imaging and histopathologic examination. [ncbi.nlm.nih.gov]

  Results The patient suffered from progressive mild thoracic backache followed by truncal and lower extremity weakness, numbness and urinary retention. The diagnosis was confirmed by magnetic resonance (MR) imaging and histopathologic examination. [springermedizin.de]

  Case 2 A 68-year-old woman presented with a 2-month history of progressive lower and upper extremity weakness and urinary retention, bilaterally decreased sensation in lower extremities, and a poor rectal tone. [ajnr.org]

• Incontinence

  Case Reports Case 1 A 47-year-old woman presented with a 2-year history of truncal and lower extremity weakness, numbness from the nipple line down to the feet, bowel and bladder incontinence, and increased reflexes in her lower extremities. [ajnr.org]

  He reported no fever, cough, trauma, changes in weight, or bowel/urinary incontinence. His past medical history was significant for HIV infection. [jpgmonline.com]

• Microscopic Hematuria

  Additionally, simple microscopic hematuria was found in 1 case suggestive of renal involvement and the other 1 complicated with interstitial lung disease. Then, a diagnosis of HSP secondary to AASV was made. [ncbi.nlm.nih.gov]

• Cranial Nerve Involvement

  Cranial nerve VIII is the most commonly involved cranial nerve, followed by CN V, VII, IX, X, and XII, with equal frequency [ 4 ]. [omicsonline.org]

  involvement and helped us to arrive at a plausible diagnosis explaining the noncontiguous cranial nerve involvement and excluded diabetic neuropathy. [jcor.in]

  Lower cranial nerves were chiefly involved in two patients whereas optic nerve was the predominantly affected nerve in one. [neurologyindia.com]

  nerve palsies with decreased sensation in the right V cranial nerve distribution. [annalsofian.org]

  Cranial nerve involvement with Lyme borreliosis demonstrated by magnetic resonance imaging. Neurology 1992;42: 671-3. [44] Lee JH, Na DG, Choi KH, et al. [em-consulte.com]

• Papilledema

  Clinical features include headache, cranial nerve impairment, paraparesis or tetraparesis, ataxia, hydrocephalus, papilledema, hemorrhage or secondary vascular occlusions (5). [path.upmc.edu]

  Other neurologic symptoms of IHP include cranial nerve palsies (cranial nerves IV–VIII), cerebellar ataxia, seizures, and neuroophthalmic symptoms such as visual field loss, complete blindness, optic neuropathy, and increased intracranial pressure with papilledema [pubs.rsna.org]

  Her left optic disk was atrophic and there was papilledema on the right eye. Another MRI was performed and showed the same pattern of meningeal enhancement seen on the first one. [scielo.br]

• Limb Weakness

  CASE REPORT In February 2003, a 67-year-old man presented with a 4-month history of progressive lower-limb weakness and a 3-month history of disturbances to his hand movements and gait. On presentation, he was unable to walk. [yumpu.com]

  At the 10-month follow-up, the patient’s neurological status had improved, with normal upper limb function, and, despite reduced function in the lower limbs, there was some improvement, with mild weakness (Grade 4/5) in the left leg and severe weakness [doi.org]

  There was mild proximal weakness in all four limbs with attenuation of reflexes in right upper limb. Investigations revealed high ESR, and normal hemogram, renal and liver function tests. [neurologyindia.com]

• Unable to Walk

  ABSTRACT We report a case of idiopathic hypertrophic spinal pachymeningitis in a 56-year-old woman who complained of a tingling sensation and progressive weakenss of both legs since 6 months prior, and then was unable to walk for 1 week. [jpatholtm.org]

  On presentation, he was unable to walk. He had a history of hypertension, diabetes mellitus, and hyperlipidaemia. [yumpu.com]

Serology for HIV, VDRL and vasculitis workup was negative. Serum ACE level was 20 U/L (8-52 U/L). CECT chest was normal. [annalsofian.org]

Case details (continued) The further workup revealed a HIV virus load of 198,322 and CD4 count of 281 cells/μL (normal range: 490-1740 cells/μL). Tuberculin skin test reading was positive 8 mm. [jpgmonline.com]

[…] fibrosis. [14] Chronic periaortitis had been recognized as a common manifestation of IgG4RD, and it commonly affects abdominal aorta; it often coexists with autoimmune pancreatitis, another prototype manifestation of this disease. [15] In the diagnostic workup [indianjrheumatol.com]

• Albuminuria

  […] leucocythaemia a pathognômonic sign of any one patho- were very loose and very light in colour; the urine was logical process, seems to me as unscientific as if we were scanty, with excess of uric acid, but without albumen; still to use the terms " jaundice" or "albuminuria [kundoc.com]

• Lymphocytic Infiltrate

  Nakamura T, Hirakawa K, Higashi S, Tomoda K, Tsukano M, Iyama K, Sakae T (2007) CD8+ T lymphocytes infiltrate predominantly in the inflammatory foci of MPO-ANCA-positive thoracic hypertrophic pachymeningitis in a patient with HLA-A24. [springermedizin.de]

  Pathologic examination of the dura revealed dense collagen bundles with lymphocyte and histiocyte infiltration. There was no evidence of tumor, granuloma, acid fast organisms or fungi. (See fig. 4) Cultures of the excised dura were negative. [ajns.paans.org]

Spinal canal decompression and autogenous bone grafting are accepted treatments in the young patient. Careful observation of the patient to watch for local progression is necessary. [ncbi.nlm.nih.gov]

Most patients improve after decompressive surgery; however, continued progression after surgical treatment has been reported. [ajns.paans.org]

The prognosis of idiopathic HSP with positive inflammatory signs may be worse; the authors stress the significance of early surgical treatment. [ncbi.nlm.nih.gov]

Keywords Idiopathic hypertrophic spinal pachymeningitis Radiculalgia CSF Therapy Prognosis This is a preview of subscription content, log in to check access. [link.springer.com]

Although many associated diseases have been suggested, the etiology of IHSP is not well understood. The ideal treatment is controversial. [londonspine.com]

Neurosurgery, Penn State Hershey Medical Center, Hershey, Pennsylvania, USA. [email protected] Abstract Spinal idiopathic hypertrophic pachymeningitis (IHP) is a rare, chronic, nonspecific, granulomatous inflammatory disorder of the dura with unknown etiology [ncbi.nlm.nih.gov]

HP has diverse etiologies like infections, chronic inflammatory processes, collagen vascular diseases and malignancy. [ijpmonline.org]

In epidemiology, it may be used to analyze a closely grouped series of events or cases of disease or other health-related phenomenon with well-defined distribution patterns in relation to time or place or both. [bioportfolio.com]

The epidemiology and pathogenesis of IgG4-RHP are poorly un-derstood. [docslide.com.br]

Epidemiology Pachymeningitis is most often found in infants and in middle-aged men. [iliveok.com]

Epidemiology of sarcoidosis in the Isle of Man: evidence for space time clustering. Thorax 1987;42:427-430. [ Links ] 27. Kern DG, Neil MA, Wrenn DS, Varone JC. Investigation of an unique time-space cluster of sarcoidosis in firefighters. [scielo.br]

[An unsolved epidemiological problem: cerebrospinal meningitis in Africa. Apropos of a recent epidemic in Niger]. Med Trop (Mars) 1961 Sep-Oct; 21 :491–525. [ PubMed ] [ Google Scholar ] LAPEYSSONNIE L, LOUIS J, BONNARDOT R, LEFEVRE M. [ncbi.nlm.nih.gov]

Abstract In pathophysiology and clinical practice, the intracranial pressure (ICP) profiles in the supratentorial and infratentorial compartments are unclear. [ncbi.nlm.nih.gov]

Idiopathic HSP is a clinical emergency and early surgical intervention is essential to prevent irreversible damage to the nervous system. [Indexed for MEDLINE] Free full text [ncbi.nlm.nih.gov]

Idiopathic HSP is a clinical emergency and early surgical intervention is essential to prevent irreversible damage to the nervous system. [jstage.jst.go.jp]

Meningitis at Curlie Meningitis Centers for Disease Control and Prevention (CDC) [en.wikipedia.org]