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Spindle Cell Lipoma

Presentation

[…] subtype: contains dilated endothelial lined channels and nodules of floating tumor (Histopathology 1994;24:565, Pathol Int 2007;57:26) Plexiform variant has been described (Histopathology 1995;27:533) Focal cartilaginous and osseous metaplasia rarely present [pathologyoutlines.com]

Intraosseous lipoma of mandible presenting as a swe- lling. Oral Maxillofac Pathol ;17:126-8. [ Links ] 4. J. G. A. M. de Visscher, (1982). [scielo.sa.cr]

Arch Pathol Lab Med 113:547–550 PubMed CAS Google Scholar Fletcher CD, Stirling RW (1990) Intranodal myofibroblastoma presenting in the submandibular region: evidence of a broader clinical and histological spectrum. [link.springer.com]

Entire Body System

  • Swelling

    Coronal CT of posterior neck swelling MRI characteristics Prognostic factors Benign lesion, no risk of metastasis Local recurrence is rare even with incomplete excision (Cancer 1975;36:1852) Case reports 47 year old man with upper back mass (J Clin Diagn [pathologyoutlines.com]

Treatment

Mod Pathol 17:547–552 CrossRef PubMed CAS Google Scholar Holden CA, Spittle MF, Jones EW (1987) Angiosarcoma of the face and scalp, prognosis and treatment. [link.springer.com]

[…] with spindle cell lipoma of oral cavity (Acta Cytol 2001;45:93) 62 year old man with spindle cell lipoma of tongue (Head Neck Pathol 2015;9:253) 66 year old man with subcutaneous mass on posterior neck with palisading pattern (J Dermatol 2021;48:e351) Treatment [pathologyoutlines.com]

Prognosis

Mod Pathol 17:547–552 CrossRef PubMed CAS Google Scholar Holden CA, Spittle MF, Jones EW (1987) Angiosarcoma of the face and scalp, prognosis and treatment. [link.springer.com]

Etiology

13q14 where the RB1 gene resides (Int J Cancer 2003;103:616) Part of the so called 13q / RB1 family of tumors, which includes myofibroblastoma and cellular angiofibroma (Hum Pathol 2012;43:1887, Am J Surg Pathol 2016;40:3617, Mod Pathol 2011;24:82) Etiology [pathologyoutlines.com]

Epidemiology

[…] floret-like giant cells Terminology Dendritic fibromyxolipoma (not recommended) ICD coding ICD-O: 8857/0 - spindle cell lipoma ICD-11: 2E80.0Z & XH30M7 - lipoma, unspecified & pleomorphic lipoma 2E80.0Z & XH4E98 - lipoma, unspecified & spindle cell lipoma Epidemiology [pathologyoutlines.com]

Pathophysiology

2015;66:430, Am J Clin Pathol 2016;146:487) Cases in women more likely to arise in atypical locations (Am J Surg Pathol 2017;41:1267) Intramuscular and dermal based lesions rarely seen (Am J Clin Pathol 2016;146:487, Am J Dermatopathol 2000;22:496) Pathophysiology [pathologyoutlines.com]

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