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Spindle Cell Sarcoma of the Duodenum

Spindle Cell Sarcoma of Digestive Tract


Presentation

  • IDCS classically presents with localized cervical or axillary lymphadenopathy.[pagepress.org]
  • Spindle cell sarcoma of esophagus: A rare case presentation.[cancerjournal.net]
  • Conclusion: With regard to the literature, IDCS presents with a wide spectrum of clinical manifestations, and its correct diagnosis requires awareness of this rare disease and the use of appropriate markers.[karger.com]
  • , but may be variable Benign and mixed patterns may be present in same tumor; extensive sampling recommended Microscopic (histologic) images Images hosted on PathOut server: Contributed by Andrey Bychkov, M.D., Ph.D., Kameda Medical Center Spindle cells[pathologyoutlines.com]
  • They are not involved other combinations of malignant cells present in another category of connective tissue, therefore they termed as undifferentiated sarcoma cells.[cancerwall.com]
Pathologist
  • Outstanding images – including gross pathology, a wide range of pathology stains, and detailed medical illustrations – make this an invaluable diagnostic aid for every practicing pathologist, resident, or fellow.[books.google.com]
  • I asked one of my pathologists about this one. He said that based on the limited information given, one could not classify this as malignant. He thought a better interpretation would be as unspecified.[aapc.com]
  • A pathologist examines the biopsy under a microscope. After putting together clinical findings, special studies on tissues (if needed) and with microscope findings, the pathologist arrives at a definitive diagnosis.[dovemed.com]
  • Although their features are readily distinguishable on routine H&E-stained slides, pathologists should be aware that fibromatoses may react with some comercially available CD117 antibodies.[nature.com]
Surgical Procedure
  • procedure performed to partially remove a portion of a lung Sleeve lobectomy: It is another surgical procedure to partially remove a portion of the lung and a part of the airway (bronchus) Pneumonectomy: It is the surgical removal of the entire lung[dovemed.com]
Inguinal Lesions
  • Amyloidosis Kidney tumors Lung - interstitial pneumonias Mediastinum / Thymus Odontogenic / Jaw Cyst Pancreas Peripheral nerve tumors Prostate Small Round Blue Cell Tumors Soft tissue Adipose differentiation Fibrous differentiation Myxoid and perineal/inguinal[surgpathcriteria.stanford.edu]
Intestinal Disease
  • Disease (IPSID) Intravascular Large Cell Lymphoma KSHV-associated Germinotropic Lymphoproliferative Disorder Lymphomatoid Granulomatosis Lymphomatoid Granulomatosis Variant of Diffuse Large B Cell Lymphoma Lymphoplasmacytic Lymphoma Mantle Cell Lymphoma[surgpathcriteria.stanford.edu]
Gastropathy
  • Autoimmune Atrophic Gastritis Chemical Gastritis / Reactive Gastropathy Collagenous Gastritis Dieulafoy Lesion / Caliber Persistent Artery Eosinophilic Gastroenteritis Gastric Antral Vascular Ectasia Granulomatous Gastritis Helicobacter Gastritis Lymphocytic[surgpathcriteria.stanford.edu]
Ulcer
  • Topics discussed include anomalies, gastritis, peptic ulceration, hyperplasias and benign epithelial tumors, carcinoma of the stomach and duodenum, carcinoid tumors, reactive and neoplastic lymphoid lesions, gastric smooth muscle and nerve sheath tumors[books.google.com]
  • We are going to another vet tomorrow to discuss debulking, in order to avoid the lump turning Necrotic, infection, ulceration, and to slow the rate of growth.[cancercompass.com]
  • However the surface of the lesion may sometimes be ulcerated or inflamed.[tropicalgastro.com]
  • Colitis Ulcerative Jejunoileitis Back to Top Gastrointestinal Tract (Neoplasms and Tumors) See sections below for Upper GI, Appendiceal tumors, Colorectal tumors, Anal tumors, Neuroendocrine tumors, Stromal lesions, Hamartomas, Nerve sheath tumors UPPER[surgpathcriteria.stanford.edu]
  • Microscopic examination revealed a cellular tumor involving the sub mucosa, muscularis propria and subserosa of the small intestinal wall with superficial mucosal ulceration.[hoajonline.com]

Workup

  • This case report addresses the clinicopathological features and differential diagnosis of extraskeletal osteosarcoma and the importance of clinicopathological correlation in the diagnosis and workup of such cases.[hoajonline.com]
Gastric Lesion
  • In 11 endosonographic series, including a total of 1181 predominantly gastric lesions, extraluminal compression was found in 29% of all patients with suspected SML[ 6 ].[tropicalgastro.com]

Treatment

  • Treatment and prognosis There is no standard treatment.[radiopaedia.org]
  • […] commonly used treatment is surgery.[dovemed.com]
  • If the histological study of the cell sample demonstrates the findings of the spindle shaped cells with malignancy, then it confirms the incidence of the spindle cell sarcoma. (2, 4) Treatment The various treatment modalities of spindle cell sarcoma comprise[cancerwall.com]
  • Here are a few important Q&A’s: Spindle cell carcinoma treatment Breast Cancer Surgery Cryotherapy Radiotherapy Hormone therapy Chemotherapy The choice of treatment depends on the location and the size of the tumor.[breast-cancer.ca]
  • Thus, developing an individualized treatment plan with your Cancer Treatment Centers of America (CTCA) sarcoma care team is extremely important.[cancercenter.com]

Prognosis

  • The prognosis for a stage 1 tumor excision is usually fairly positive, but if the tumors progress to levels 2 and 3, prognosis is worse because tumor cells have likely spread to other locations.[en.wikipedia.org]
  • Treatment and prognosis There is no standard treatment.[radiopaedia.org]
  • In some cases, amputation of the involved part is needed due to extension of malignancy, which creates severe harms to associated tissues. (2,4,5) Prognosis The treatment, prognosis is better if the diagnosis is conducted and detected the disease in the[cancerwall.com]
  • The prognosis for spindle cell breast cancer is basically similar to the prognosis for other more common breast carcinomas, though at times it can be a highly aggressive neoplasm.[breast-cancer.ca]
  • The prognosis of the condition is generally poor.[dovemed.com]

Etiology

  • ICD-10-CM Codes › C00-D49 Neoplasms › C7A-C7A Malignant neuroendocrine tumors › Use Additional Use Additional Help Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology.[icd10data.com]
  • It has been hypothesized that IDCS has a viral etiology, but no association to any virus has been shown. 9 Although IDCS has been found on the eyelid, 4 pleura, 8 tonsil, 7 testes, 10 lung, 11 spleen, 12 and parotid gland, 9 it rarely involves these extra-nodal[pagepress.org]
  • (Etiology) The exact cause of Spindle Cell Carcinoma of Lung is unknown.[dovemed.com]
  • The etiology remains unknown though it is assumed to reflect a reparative response although the stimulus is not clear; prior trauma/surgery is usually not reported.[nature.com]
  • The etiology may be an exaggeratedproliferative response to infection, trauma, peptic ulcer, surgery, radiotherapy, chemotherapy, or steroid use[ 59 ]. IMFT are most common in the lung, but can arise in any organ.[tropicalgastro.com]

Epidemiology

  • Pathology of the Stomach and Duodenum comprehensively surveys gastric and duodenal disease, including clinical findings, pathophysiology, and epidemiology, and emphasizing diagnostic gross and microscopic pathology.[books.google.com]
  • Conclusions In this discussion we highlighted the epidemiology, diagnostics, treatments, and outcomes associated with IDCS. Primary surgical resection is the mainstay treatment for early stage disease.[pagepress.org]
  • For years, the epidemiological features of KS, including the observation of disease in defined patient populations and the geographic distribution, were suggestive of an infectious etiology.[nature.com]
Sex distribution
Age distribution

Pathophysiology

  • Pathology of the Stomach and Duodenum comprehensively surveys gastric and duodenal disease, including clinical findings, pathophysiology, and epidemiology, and emphasizing diagnostic gross and microscopic pathology.[books.google.com]
  • Existing literature on the incidence, pathophysiology and treatment strategies is also examined. carcinogenesis gastrointestinal surgery general surgery colon cancer Statistics from Altmetric.com Request Permissions If you wish to reuse any or all of[casereports.bmj.com]
  • Pathophysiology of Spindle Cell Sarcoma Orbit Orbital solitary fibrous tumours show mesenchymal and/or fibroblastic differentiation and have a strong and diffuse immunoreactivity to CD 34.[eyeplastics.com]
  • BASAL CELL CARCINOMA OVERVIEW AND PATHOPHYSIOLOGY Basal cell carcinoma flgayl the most common skin cancer can flagyl cure a urinary tract infection Caucasians. в Accurate placement of ports in the intercostal spaces avoids postoperative intercostal neuralgia[artem-kuzmin.ru]

Prevention

  • The chance of recurrence leaves room for close clinical follow-up and review surgery, but there is no conclusive evidence supporting radiotherapy or chemotherapy for prevention of recurrence.[eyeplastics.com]
  • How can Spindle Cell Carcinoma of Lung be Prevented? Currently, there is no known prevention method for Spindle Cell Carcinoma of Lung.[dovemed.com]
  • Prevention The measures to prevent choroidal effusion are the cue as that for hypotony due to can flagyl cure a urinary tract infection. Plate TLC silica gel plate R.[artem-kuzmin.ru]
  • Post operative radiation therapy is used in most cases in the hopes of preventing local recurrence or metastasis.[breast-cancer.ca]

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