Based on this result and using data from different Genome Databases, we performed an interspecies comparison of exon 47 and discovered that the poly(Q) tract is present in all the species studied, with the exception of primitive fish and rodents. [ncbi.nlm.nih.gov]

However, abnormalities in the pharyngeal phase in SCA6 were indistinguishable from those in SCA3, with no explainable reason. To determine the reason, we repeatedly performed videofluoroscopic examinations (VF) in 14 patients with SCA6. [ncbi.nlm.nih.gov]

SCA6 patients had a reduction in slow wave sleep and a higher frequency of snoring and respiratory disorders during sleep when compared to the control group. 2016 European Sleep Research Society. [ncbi.nlm.nih.gov]

SCA6 patients had a reduction in slow wave sleep and a higher frequency of snoring and respiratory disorders during sleep when compared to the control group. 2016 European Sleep Research Society. [ncbi.nlm.nih.gov]

We found that conventionally monitored somatosensory evoked potentials at least partly reflected progressive dysphagia. [ncbi.nlm.nih.gov]

Expansions of the CAG repeat in the CACNA1A gene on the short arm of the chromosome 19 induce SCA6, and point mutations in the same gene are responsible for EA2 and FHM. [ncbi.nlm.nih.gov]

In addition, clinical and neuro-otological examinations suggested that SCA6 is a disease with predominantly cerebellar dysfunction. [ncbi.nlm.nih.gov]

Some patients have ataxia combined with episodic headaches or nausea, suggesting an overlap among SCA6, eposidic ataxia type 2, and familial hemiplegic migraine. [ncbi.nlm.nih.gov]

Clinical manifestations were pleomorphic, including episodes of altered consciousness precipitated by minor head trauma, focal neurological deficits precipitated or not by minor head trauma, and migraine without aura, besides progressive late-onset cerebellar [doi.org]

Ischemic changes, homozygous mutation, and diabetes mellitus as well as aging might have contributed to the observed progressive dysphagia. [ncbi.nlm.nih.gov]