Presentation
We report a case of splenosis presenting as occult GI bleeding that was eventually treated with transarterial embolization. [ncbi.nlm.nih.gov]
Entire Body System
- Asymptomatic
Most cases are asymptomatic, so further treatment is rarely required; all cases are managed conservatively. [ncbi.nlm.nih.gov]
- Weight Loss
He denied having cough, fever, or weight loss. His medical history included non-insulin-dependent diabetes, peptic ulcer disease, and splenectomy following a gunshot injury sustained during the Korean War in 1950. [nejm.org]
A 37-year-old man presented with episodes of periumbilical abdominal pain associated with weight loss for about one month. His past medical history included splenectomy. [scielo.isciii.es]
(Fig 1) He denied any constitutional symptoms (weight loss, fever, malaise), and was on no regular medications. He drank five units of alcohol per week. [surgicalexam.com]
At elective gastroscopy 3 weeks later, the patient reported increasing fatigue and an unintended weight loss of 7 kg. On clinical examination, he was icteric. [karger.com]
The patient was asymptomatic, especially there were no complaints of fever, night sweats or weight loss. Laboratory tests did not show pathological results. [thieme-connect.com]
- Anemia
A 56-year-old woman was referred to our hospital because of abdominal distention and anemia. The abdomen was markedly distended. [ci.nii.ac.jp]
Slight anemia of 7.2 mmol/l (normal range 8.3-10.5 mmol/l) and thrombocytosis of 424 × 10 9 /l (normal range 145-350 × 10 9 /l) were also found. [karger.com]
- Ascites
Due to the fact that uterine cancers can metastasise on the surface of the peritoneum and the patient’s history of cancer, we considered lymphadenopathies then peritoneal carcinomatosis, which is characterised by nodules, ascites and thickening of the [em-consulte.com]
Gastrointestinal
- Abdominal Pain
A 52-year-old man presented with abdominal pain with a background of splenectomy 25 years previously. Initial investigations lead to suspicion of a neuroendocrine tumour. Positron emission tomography octreotide scanning and chromogranin were raised. [ncbi.nlm.nih.gov]
We present the first case of laparoscopic resection of a pancreatic splenosis, in a patient who had undergone a splenectomy 31 years before, complaining of abdominal pain and diarrhea. [unboundmedicine.com]
- Pelvic Mass
Keywords Splenosis, pelvic mass, tubal splenosis, pelvic pain Financial Disclosure The authors report no conflict of interest. Rights Copyright © 2017 the authors Recommended Citation Baki S, Basbug A, Hanege BY, Özsan N. [ir.uiowa.edu]
Pelvic splenosis mimicking endometriosis causing low abdominal mass and pain. Human Reproduction 1998; 13 (6) : 1683-85. 5.Higgins RV, Crain JL. Laparoscopic removal of pelvic splenosis. Jour of Reproductive Med 1994; 40 (2) : 140-42. [bhj.org.in]
Cardiovascular
- Hypertension
A 22-year-old man with chronic glomerulonephritis, hypertension and a childhood history of splenectomy was hospitalized for a hypertensive emergency. He did not improve with aggressive antihypertensive therapy. [ncbi.nlm.nih.gov]
A 60 yrs old male, smoker, with a past medical history of hypertension, and remote h/o post trauma splenectomy presented with symptoms of UTI. [nuclearmd.com]
The correlation between haematological markers such as Howell – Jolly bodies has been evaluated by studies in patients with medical causes for hyposplenism, such as sickle cell disease and coeliac disease, as well as embolization utilized in portal hypertension [academic.oup.com]
His medical history included atrial fibrillation, hypertension, obstructive sleep apnea, asthma, and splenectomy at age 14 following a traumatic splenic rupture after being kicked by a horse. [dovepress.com]
Patient’s medical history was significant for hypertension, insulin-dependent diabetes mellitus and moderate chronic renal failure. Complete abdomen ultrasound and bone scans were negative. [jtd.amegroups.com]
Musculoskeletal
- Fracture
The physical examination was unremarkable, and chest radiography showed a healed fracture of the. .. Paramjit Singh, M.D. Nancy J. Munn, M.D. Hitendra K. Patel, M.D. Marshall University School of Medicine, Huntington, WV 25701 [nejm.org]
Urogenital
- Testicular Pain
Splenosis as a cause of testicular pain: laparoscopic management. [Splenosis as a cause of testicular pain: laparoscopic management.] J. Endourol., 1999; 13: 5: 373–375. Martin L.W. Autologous splenic transplantation. [vestnik-surgery.com]
Splenosis as a cause of testicular pain: laparoscopic management J Endourol. 1999; 13(5):373-5. [PMID: 10446800] Kiroff GK, Mangos A, Cohen R, Chatterton BE, Jamieson GG. Splenic regeneration following splenectomy for traumatic rupture. [pancreas.imedpub.com]
Neurologic
- Confusion
Here we present a case of splenosis in the setting of a history of malignancy which illustrates well the potential for diagnostic confusion that can be caused by this entity. [ispub.com]
Splenosis should not be confused with polysplenia or accessory spleens (splenunculi), which are congenital and retain arterial supply from the splenic artery. They are also composed of normal splenic tissue. [radiopaedia.org]
It is often confused with malignant lesion or tumour recurrence [ 2 ]. We are reporting a case of splenic tissue in pouch of Douglas, 35 years after splenectomy for traumatic splenic injury. [casereports.in]
They can be confused with other entities including peritoneal carcinomatosis, endometriosis, and metastatic disease (1-5). [scielo.isciii.es]
[…] pictured). [17] If splenectomy is performed for conditions in which blood cells are sequestered in the spleen, failure to remove accessory spleens may result in the failure of the condition to resolve. [1] During medical imaging, accessory spleens may be confused [en.wikipedia.org]
Workup
In the workup of pulmonary nodules in patients with a history of trauma, splenosis should be a consideration. [ncbi.nlm.nih.gov]
X-Ray
- Pleural Mass
All the patients were Caucasians male aged 40-63 presenting with pleural masses that mimicked malignancy, who were eventually diagnosed as thoracic splenosis. [erj.ersjournals.com]
Therefore, without the clinical information, these nodules may be mistaken for pleural masses including pleural metastasis, lymphoma, or malignant mesothelioma. [e-sciencecentral.org]
According to National Guidelines Clearinghouse, there are three accepted options in the management of patients with intrathoracic nodules or masses of unknown origin: percutaneous biopsy of pleural masses under CT guidance, fluorine-18-fluoro-2-deoxy-D-glucose [link.springer.com]
Serum
- Howell-Jolly Bodies
7 Howell – Jolly body counting as a measure of splenic function. [academic.oup.com]
The diagnosis of intrathoracic ectopic spleen was suspected because of the history of spleen trauma with diaphragm rupture and the absence of Howell-Jolly bodies. [ncbi.nlm.nih.gov]
Gastric splenosis should be considered as a possible etiology for subepithelial masses in patients with prior splenic trauma or surgery, particularly if their peripheral blood smear does not show Howell-Jolly bodies. 4,5 Figure 4. [acgcasereports.gi.org]
A peripheral blood smear revealed the absence of Howell-Jolly bodies indicating the presence of splenic function. [ispub.com]
Jolly bodies on blood smear of patient with history of splenectomy and by scintigraphy using heat damaged Tc-99 labelled autologous red blood cells. [bhj.org.in]
Microbiology
- Streptococcus Pneumoniae
Clinical Nuclear Medicine 22(4):271-272, 1997 6) Dickerman JD, Horner SR, Coli JA, Gump DW: The protective effct of intraperitoneal splenic autotransplants in mice exposed to an aerosolised suspension of type III Streptococcus Pneumoniae. [surgicalexam.com]
The protective effect of intraperitoneal splenic autotransplants in mice exposed to an aerosolized suspension of type III Streptococcus pneumoniae. Blood. 1979; 43 354-358 19 Moxon E R, Schwartz A D. [thieme-connect.com]
Treatment
By means of this case report and 31 literature reviews, potential treatment modalities concerning clinical diagnostics, patient's management could be discussed.The report presents the case of a 33-year-old man with a liver lesion. [ncbi.nlm.nih.gov]
[…] heat-damaged erythrocyte study is more specific because of reduced uptake of 99m Tc in otherwise normal liver tissue. 3 When a localised area of uptake corresponding to the mass is detected — supporting the diagnosis of thoracic splenosis — no further treatment [mja.com.au]
Prognosis
Treatment and prognosis Management is expectant in almost all cases where surgery is considered only indicated in occasional symptomatic patients and in situations where diagnosis is doubtful and when it is not possible to exclude malignancy. [radiopaedia.org]
Etiology
Article analyzes current data on macroamylasemia and splenosis, their etiology and diagnostics in particular. [ncbi.nlm.nih.gov]
Etiology Abdominal splenosis is seen after abdominal trauma or surgery (e.g. splenectomy). It results from seeding of the peritoneal cavity with splenic tissue which recruits local blood supply. [radiopaedia.org]
Gastric splenosis should be considered as a possible etiology for subepithelial masses in patients with prior splenic trauma or surgery, particularly if their peripheral blood smear does not show Howell-Jolly bodies. 4,5 Figure 4. [acgcasereports.gi.org]
This is evidence of the great importance of determination of the proper etiology of clinical symptoms such as chronic cough or thoracic pain. [link.springer.com]
Distinguishing the etiology of hepatic nodular lesions is important because it significantly alters therapeutic procedures. [oatext.com]
Epidemiology
Neurology and Neurosurgery Czech and Slovak Ophthalmology Czech and Slovak Psychiatry Czech Geriatric Review Czech Gynaecology Czech Rheumatology Czech Dental Journal Czech Urology Czech-Slovak Dermatology Czecho-Slovak Pathology Czech-Slovak Pediatrics Epidemiology [prolekare.cz]
Pathophysiology
Author information 1 Division of Radiology, Department of Pathophysiological and Therapeutic Science, Faculty of Medicine, Tottori University, 36-1 Nishi-cho, Yonago, Tottori, 683-8504, Japan. [email protected] Abstract Splenosis represents the [ncbi.nlm.nih.gov]
Prevention
We report a case in which nuclear imaging was used to make the diagnosis of thoracic splenosis, thus preventing the need for invasive procedures and avoiding unnecessary patient apprehension. [ncbi.nlm.nih.gov]
Since 1981, we have specialized in treating dysfunction related to the spine and offer on and offsite spine school for prevention. [backclinicinc.com]