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Spontaneous Abortion


Presentation

  • A 22-year-old Chinese woman with HWWS whose left uterine pregnancy underwent spontaneous abortion presented with a right perforated obstructed hemivagina and right renal agenesis.[ncbi.nlm.nih.gov]
Recurrent Abdominal Pain
  • It is usually diagnosed after menarche, with a clinical presentation of dysmenorrhea, recurrent abdominal pain, and irregular menses. However, it is rare to diagnose it during pregnancy, subsequently resulting in spontaneous abortion.[ncbi.nlm.nih.gov]
Fracture
  • Rates of transcervical and pertrochanteric hip fractures in the Province of Quebec, Canada, 1981–1992. Am J Epidemiol 1995 ; 142 : 428 –36. 20. Einarson A, Choi J, Einarson TR, et al.[doi.org]
Psychiatric Symptoms
  • Most studies 31 – 34 have found that a significant percentage of women experience psychiatric symptoms in the weeks to months after spontaneous abortion.[aafp.org]
Foul Smelling Vaginal Discharge
  • Symptoms of an infection include fever, vaginal bleeding that does not stop, cramping, and a foul-smelling vaginal discharge. Infections can be serious and need immediate medical attention.[nlm.nih.gov]
  • Signs and symptoms of this infection include: Fever Chills Lower abdominal tenderness Foul-smelling vaginal discharge Prevention Often, there's nothing you can do to prevent a miscarriage.[mayoclinic.org]
  • Women who have had an unsafe abortion usually come to the health care facility with the following signs and symptoms: ‐ vaginal bleeding ‐ abdominal pain ‐ fever ‐ purulent or foul smelling vaginal discharge ‐ shock The interventions which the health[doi.org]

Workup

  • Although MRIs are not involved in the SA workup, an MRI study was ordered in the ED in the background of otherwise normal findings to asses for a potential appendicitis, which has been commonly reported during pregnancy in the literature [ 11 ].[openaccessjournals.com]
  • Bourne, There is no role for uterine curettage in the contemporary diagnostic workup of women with a pregnancy of unknown location, Human Reproduction, 21, 10, (2706), (2006).[doi.org]
  • It is of utmost importance that the laboratory has its interest invested in infertility workups.[fertilitysolution.com]
  • Procedures When the diagnosis is unclear, the following procedures may be performed: Culdocentesis Diagnostic dilation and curettage See Workup for more detail.[reference.medscape.com]
Clostridium Perfringens
  • Although obstetric mortality due to complications of Clostridium perfringens infection is rare at present, we report a case of fatal clostridial sepsis secondary to a septic spontaneous abortion.[ncbi.nlm.nih.gov]

Treatment

  • The positive rate of ACA in failure group before treatment was higher than the data of after treatment, and the difference was statistically significant (p 0.05).[ncbi.nlm.nih.gov]
  • Traditional treatment consisting of surgical evacuation of the uterus remains the treatment of choice in unstable patients. Recent studies suggest that expectant or medical management is appropriate in selected patients.[aafp.org]

Prognosis

  • Speert, H. ( 1954 ) Pregnancy prognosis following repeated abortion. Am. J. Obstet. Gynec. 68, 665. Spicer, C.C. & Lipworth, L. ( 1966 ) Regional and Social Factors in Infant Mortality.[cambridge.org]
  • Liu et al ( 29 ) demonstrated that IGFBP-7 was downregulated in gastric cancer, and that it may be used as an indicator of poor prognosis in patients with gastric cancer.[spandidos-publications.com]
  • Prognosis Threatened miscarriage is associated with risk of subsequent preterm delivery. Increased risk of further miscarriages. After three miscarriages, consider as recurrent spontaneous miscarriage.[patient.info]

Etiology

  • Only etiologic studies were considered. Results. Fifteen studies met inclusion criteria.[doi.org]
  • The data are still incomplete regarding the etiologic role, if any, of cytomegalovirus and the occurrence of spontaneous abortion.[ncbi.nlm.nih.gov]

Epidemiology

  • Dose-response and trend analysis in epidemiology: alternatives to categorical analysis. Epidemiology 1995 ; 6 : 356 –65. 29. Ford JH, MacCormac L, Hiller J.[doi.org]
  • Department: Institutionen för medicinsk epidemiologi och biostatistik / Department of Medical Epidemiology and Biostatistics Abstract The overall objectives of this thesis were to increase the understanding of the etiology of spontaneous abortion and[openarchive.ki.se]
  • Author information 1 Division of Cancer Epidemiology and Management, Center for Uterine Cancer, National Cancer Center, Ilsandong-gu, Goyang, Republic of Korea. 2 Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.[ncbi.nlm.nih.gov]
Sex distribution
Age distribution

Pathophysiology

  • All miscarriages are the result of a pathophysiologic reproductive event. It is the current challenge of medicine to find those underlying causes and, in some cases, underlying causes that are common occurrences are often overlooked.[naprotechnology.com]
  • The pathophysiology of cervical insufficiency is still poorly understood.[doi.org]
  • "This approach is currently criticized as our insight into the pathophysiology of miscarriage has improved, and it has become clear that there is lack of evidence to support the [efficacy] of bed rest in this condition."[medscape.com]

Prevention

  • We conclude that anticoagulation without concurrent prednisone or aspirin may provide an alternative approach to prevention of habitual abortion in some women with lupus anticoagulants.[ncbi.nlm.nih.gov]

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