PSP typically manifests in young men who are tall, thin, and likely to be smokers [9]. This subtype occurs in ages of 20 to 30 years. However, SSP develops in individuals aged 60 to 65 who exhibit underlying disease.

The presentation typically consists of a sudden onset of sharp pleuritic pain, which may radiate to the neck, shoulder, or abdomen. The pain subsides within 24 hours [10] as the lung adapts by slowly re-inflating.

The features are varied as some patients have mild dyspnea while others develop sequelae such as shock and possibly death. Factors that determine the severity include the amount of air that enters the pleural space, the percentage of lung collapse, and the baseline lung function.

Physical exam

Clinical findings that reflect a large pneumothorax include decreased or absent breath sounds, less movement of the chest wall, tympanic percussion, and reduced tactile fremitus [11]. Additionally, reflex tachycardia is common.

• Tall Stature

  Risk Factors See Primary Spontaneous Pneumothorax regarding body habitus Tall Stature Low BMI See Secondary causes above Tobacco Abuse Increases the risk of both primary and Secondary Spontaneous Pneumothorax May increase lifetime risk from 0.1% in non-smokers [fpnotebook.com]

  Tall stature and low body mass index are also associated with higher rates of PSP. It is hypothesised that the RB develops in smokers and leads to the development of ELC in patients predisposed to this process. [karger.com]

• Marfanoid Habitus

  On physical examination he presented with marfanoid habitus. Pneumothorax was managed conservatively with resolution. [ncbi.nlm.nih.gov]

• Pseudotumor

  We obtained pathological diagnosis of inflammatory pseudotumor and surrounding atelectasis. He was cured from pneumothorax and pulmonary tumors. [ncbi.nlm.nih.gov]

• Dyspnea

  Case 1, a 43-year old man was admitted to our hospital with dyspnea 10 days before admission. He denied any recent trauma or previous treatment for lung tuberculosis. [ncbi.nlm.nih.gov]

• Hyperresonance

  […] symptoms (e.g. general malaise, fatigue) are less commonly observed Signs General appearances may be normal Sweating, tachypnoea, tachycardia (most common finding) Splinting of the chest wall to relieve pleuritic pain Decreased or absent breath sounds Hyperresonance [rch.org.au]

  Tachycardia is the most common finding and, depending on the amount of lung involved, other physical findings include decreased chest wall movement, a hyperresonant percussion note, diminished fremitus and diminished or decreased breath sounds. [aafp.org]

  Signs Examination may be unremarkable Tachycardia may be the only clinical finding (single most common finding) Keep high index of suspicion COPD patients Tall, thin males Changes on affected side Unilateral absent or decreased breath sounds Hyperresonance [fpnotebook.com]

  There is hyperresonance (higher pitched sounds than normal) with percussion of the chest wall which is suggestive of pneumothorax diagnosis. Chest x- rays will then be used to confirm the diagnosis of the pneumothorax. [physio-pedia.com]

• Pleuritic Pain

  The presentation typically consists of a sudden onset of sharp pleuritic pain, which may radiate to the neck, shoulder, or abdomen. The pain subsides within 24 hours as the lung adapts by slowly re-inflating. [symptoma.com]

  pain Decreased or absent breath sounds Hyperresonance on percussion Asymmetric lung expansion, mediastinal and tracheal shift with large pneumothorax Signs of tension pneumothorax Deviation of the trachea to the contralateral side, tachycardia, hypotension [rch.org.au]

  However, during the administration of the third cycle of Ifosfamide, he developed tachypnea, pleuritic pain in the chest, and tachycardia and was recovered to other hospital for the treatment of acute respiratory failure. [jtd.amegroups.com]

• Pulmonary Disorder

  Pneumothorax can also occur secondary to a variety of pulmonary disorders such as chronic obstructive pulmonary disease (COPD), pneumoconiosis, diffuse interstitial fibrosis, and infection diseases. [jtd.amegroups.com]

  Secondary spontaneous pneumothorax (SSP), unlike PSP, develops in patients diagnosed with a pulmonary disorder. [ncbi.nlm.nih.gov]

• Exertional Dyspnea

  dyspnea, fatigue, weakness, and tachycardia.[15] It may lead to heart failure.[15] Anaemia is often a cause of dyspnea. [en.wikipedia.org]

• Chest Pain

  A patient presented in the emergency setting with acute chest pain and shortness of breath caused by a tension pneumothorax. [ncbi.nlm.nih.gov]

• Cyanosis

  The most severe forms of pulmonary alveolar proteinosis, in which hypoxemia and cyanosis occur, have a high mortality risk during anaesthesia and whole lung lavage. [ncbi.nlm.nih.gov]

  Rapidly evolving hypotension, tachypnea, tachycardia and cyanosis should raise the suspicion of tension pneumothorax, which is, however, extremely rare in PSP. [err.ersjournals.com]

  […] persons artificial pneumothorax aspiration of air atelectasis barometric pressure bleeding breath sounds Bronchoscopic examination bullae cent chemical pleuritis chest wall clavicles collapsed lung condition of lungs Constitutional symptoms coughing cyanosis [books.google.com]

  Decreased or absent breath sounds Hyperresonance on percussion Asymmetric lung expansion, mediastinal and tracheal shift with large pneumothorax Signs of tension pneumothorax Deviation of the trachea to the contralateral side, tachycardia, hypotension, cyanosis [rch.org.au]

  Cyanosis or blueness of the skin will occur as the tissues lose their oxygen. Decreased levels of consciousness may occur because of the low blood pressure, decreased brain perfusion, and low oxygenation. [emedicinehealth.com]

• Skin Lesion

  Hepatic AMLs and adenoma sebaceum skin lesions were also noted, consistent with an overall diagnosis of tuberous sclerosis. [ncbi.nlm.nih.gov]

  Tuberous sclerosis complex can involve the nerves (seizures, brain tumors), the lungs (lymphangioleiomyomatosis, causing pneumothorax or chylothorax), and the skin; skin lesions include facial angiofibromas ( Figure 1 ), ash-leaf spot ( Figure 2 ), and [mdedge.com]

• Musculoskeletal Pain

  BACKGROUND: Spontaneous pneumothorax (PTX) is a diagnostic challenge in aviators given the common occurrence of musculoskeletal pain after flight and notorious underreporting of symptoms of other diseases in this group.CASE REPORT: A 24-yr-old active [ncbi.nlm.nih.gov]

The clinical assessment consists of the patient's history, the physical exam, and the appropriate tests. A large pneumothorax is diagnosed based on the exam findings.

Imaging

A pneumothorax on a chest radiograph is depicted as a collection of air as the collapsed lung is portrayed by a thin line demarcating the pleural edge. Specifically, the upright posteroanterior angle can confirm and accurately determine the size of the pneumothorax [12].

A computed tomography (CT) scan is obtained if the diagnosis is inconclusive. This modality can detect a small pneumothorax and differentiate this from other lung pathologies. CT studies can also be used to monitor the management and progress of these patients.

• Pericardial Effusion

  Alternating or phasic ECG voltage changes are most commonly associated with intrinsic myocardial electrophysiological perturbations or mechanical oscillation within a pericardial effusion. [ncbi.nlm.nih.gov]

• Cavitary Lesion

  Pneumothorax is a common complication in pulmonary tuberculosis that is usually seen with underlying cavitary lesion. However, it is uncommonly seen in patients with miliary tuberculosis. [ncbi.nlm.nih.gov]

• Normal Chest X-Ray

  On physical examination, vital signs were normal. Chest X-ray showed 33% of pneumothorax or 1.2 cm. He was asked to perform incentive spirometry therapy at home. [ncbi.nlm.nih.gov]

• Right Axis Deviation

  When an ECG has the arm leads incorrectly placed, the ECG will display right axis deviation and inversion of the P waves in lead I. [ncbi.nlm.nih.gov]

• Right Bundle Branch Block

  These findings include axis deviation, T-wave inversion, and right bundle branch block. When an ECG has the arm leads incorrectly placed, the ECG will display right axis deviation and inversion of the P waves in lead I. [ncbi.nlm.nih.gov]

• T Wave Inversion

  These findings include axis deviation, T-wave inversion, and right bundle branch block. When an ECG has the arm leads incorrectly placed, the ECG will display right axis deviation and inversion of the P waves in lead I. [ncbi.nlm.nih.gov]

• Inverted P Wave

  An ECG was administered; findings indicated reversal of the arm leads (right axis deviation and inverted P waves in lead I), but there was no actual limb lead reversal present. ECG findings resolved upon resolution of the pneumothorax. [ncbi.nlm.nih.gov]

The treatment of a pneumothorax will depend on the cardiorespiratory status, the severity of the symptoms, and the size of the defect [13] [14]. Mild cases of PSP and SSP are managed through observation while large ones require aspiration or insertion of a chest tube [15]. The latter is indicated if catheter aspiration fails to remove the air or in cases of SSP.

Some patients will warrant surgery, in which a thoracoscope is placed into the pleural space. These individuals will also need high flow oxygen.

Uncomplicated cases do not require treatment and will usually resolve in about 10 days. Recurrences occur especially in smokers and those with COPD or AIDS.

PSP is very likely caused by a ruptured subpleural bleb or bulla [1] [2] whereas SSP develops in those with underlying lung disease such as chronic obstructive pulmonary disease (COPD), cystic fibrosis (CF), infections, congenital disorders, or lung cancer [3] [4].

There may be a genetic component as well. For example, Marfan syndrome, Birt-Hogg-Dube (BHD) syndrome, and homocystinuria have been associated with PSP.

Smoking is a major risk factor as it may elevate the risk by 9 -fold [5].

The incidence of first -time spontaneous pneumothorax in men is 7.4 to 18 patients per a population of 100,000 and in women is 1.2 to 6 per 100,000 [6]. With regards to SSP, the incidence in men is 6.3 cases per 100,000 individuals and in women is 2 cases per 100,000 [7].

Normally, the pressure in the pleural space is negative due to the outward expansion of the chest wall and the intrinsic elastic recoil. Therefore, the chest has a tendency to collapse inward. Hence, when air enters this pleural space, the pressure increases while the vital capacity decreases. Additionally, there is an inverse relationship between the size of the pneumothorax and the volume of the lung. When the former expands, the latter becomes smaller.

The pathogenesis is not uniform in all individuals and has not been established with regards to how ruptured blebs or bullae could cause air to enter the pleural space [8].

Since some patients may experience recurrence. Preventive measures such as surgery may be beneficial in these patients. Surgery involves repairing the weak sites of the lung and strengthening the pleural layers by suturing them to each other.

Spontaneous pneumothorax (SP) refers to the presence of air in the pleural space. It may occur as a primary spontaneous pneumothorax (PSP) or secondary spontaneous pneumothorax (SSP) due to different etiologies. The diagnosis is made clinically with the help of imaging. Management of this condition depends on numerous factors.

What is a spontaneous pneumothorax?

This is a condition in which air enters the space between the chest wall and the lung. It may occur spontaneously, or secondary to lung diseases. Smoking increases the likelihood of developing this especially in individuals in their 20s and 30s.

What are the symptoms?

• Sharp chest pain that spreads to shoulder, neck, or abdomen
• Shortness of breath
• Dry cough

How is it diagnosed?

The clinician will ask the appropriate questions, perform a physical exam and order imaging tests such as chest x-ray and possibly a CT scan.

How is it treated?

Mild cases can be observed without any active treatment . Severe cases will require drainage of the air by either aspiration or insertion of a chest tube.

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