• Muscle Weakness

  Ventilatory insufficiency in sALS is caused by respiratory muscle weakness, being the major cause of death (84%) in these patients5, 6. [scielo.org.ar]

Phase 3 Trial of Masitinib as Add-on ALS Treatment Cleared by FDA [Internet]. [consultado 30 Abril 2020]. [revistamedicasinergia.com]

Patients receiving both treatments simultaneously had a significant longer survival. [scielo.org.ar]

Association of Serum Retinol-Binding Protein 4 Concentration With Risk for and Prognosis of Amyotrophic Lateral Sclerosis. JAMA Neurology, 75(5), p.600. https://doi.org/10.1001/jamaneurol.2017.5129 [revistamedicasinergia.com]