There were several limitations to the present study. [onlinelibrary.wiley.com]

[…] to more than half of one lobe, but is not in both lobes T2c: the tumor is present in both lobes of the prostate T3: the tumor has grown outside of the prostate and may be present in the seminal vesicles T3a: the tumor is outside of the prostate, but [zerocancer.org]

Our patient presented with mediastinal mass as the first manifestation of prostate cancer. Unusual prostate carcinoma metastases are usually encountered in the presence of known advanced disease but rarely as the first presentation. [hindawi.com]

In this particular case, we learned that the atypical presentation of metastatic PCa alone would make diagnosis difficult. We reported this case to alert urologist about the rare manner, in which PCa may sometimes present. [academic.oup.com]

• Weight Loss

  Bone pain, weight loss, swelling in the legs and feet, pelvic discomfort, erectile problems, trouble urinating, and blood in the urine and/or semen are common signs of advanced prostate cancer. [healthmonitor.com]

  Side effects include nausea, loss of appetite, and weight loss. Immunotherapy Sipuleucel-T (Provenge) is a vaccine doctors use to treat advanced prostate cancer, especially if it’s not responding to hormone therapy. [healthline.com]

  If the prostate cancer has spread, become more severe and moved to a stage 4 then you might also experience the following symptoms: Bone pain, especially around the hips, thighs and lower back Swelling of the feet and legs Weight loss Fatigue Read what [naturalprostate.com]

  More widespread disease often spreads to the bones and gives pain or unexplained weight loss and fatigue. [cancer.org.au]

• Abdominal Pain

  Contact your doctor immediately if you experience any of the following symptoms: abdominal pain, abdominal bloating, shortness of breath, dizziness, light-headedness and/or any signs of confusion In women, the most common side effects are those resulting [aboutzoladex.com]

  Green showed in her study that most common initial symptoms or findings for gastric metastasis from solid tumors were diffuse abdominal pain, nausea and vomiting, anorexia, guaiac-positive stool, and gastrointestinal bleeding, respectively [9]. [hindawi.com]

  This pain was associated with moderate lower urinary tract symptoms, progressive left lower limb edema and moderate abdominal pain. Patient denies fever, chills, vomiting, diarrhea and hematuria. [academic.oup.com]

  Once the symptomatic, including obstructive, neurological or systemic symptoms like paracancerous syndrome, bone pain, hydronephrosis, abdominal pain, bloody stools, tumor has usually already evolved to a terminal stage.2-4 Thus, the prognosis of patients [onlinelibrary.wiley.com]

• Bone Pain

  Bone pain, weight loss, swelling in the legs and feet, pelvic discomfort, erectile problems, trouble urinating, and blood in the urine and/or semen are common signs of advanced prostate cancer. [healthmonitor.com]

  Bone Pain Treatment The bones are a common place for prostate cancer to spread. Androgen deprivation therapy can often control the cancer that has spread to bones. [prostatecentre.com]

  Chemotherapy can also be highly effective in reducing bone pain. [pcf.org]

  Among other things, the spread of the prostate cancer to the bones (bone metastases) can cause severe pain and fracture, and hormonal therapy for prostate cancer can cause bone loss, fracture, and joint pain. [zerocancer.org]

  Prostate cancer often spreads to the bones, which can cause bone pain. Your doctor can offer treatments and medications to control the pain. [drugs.com]

• Back Pain

  Six appointments Therapy can be completed in a little over a month with only 6 appointments Generally well tolerated safety profile The most common side effects in clinical studies were chills, fatigue, fever, back pain, nausea, joint ache, and headache [provenge.com]

  The story so far : he was diagnosed right-off-the-bat as Stage IV prostate cancer about six months ago, after spending the previous few months complaining of upper-back pain. [boards.straightdope.com]

  Side effects may include: nausea a headache back pain joint pain Surgery While some surgery to remove tumors may be an option, your doctor is less likely to recommend it for prostate cancer that has spread to multiple areas. [healthline.com]

  pain (from metastatic spread to the spine) Clinical scores that may be useful in assessing symptoms severity include: IPSS: international prostate symptoms score, 35 points score mainly assessing urinary symptoms IIEF: international index of erectile [radiopaedia.org]

  Case Report A 69-year-old man was presented with our hospital in October 2007, with four-month history of anorexia, painless gross hematuria, and back pain. [hindawi.com]

• Low Back Pain

  […] the stream, or dribbling low back pain pain with ejaculation your doctor will diagnose prostate cancer by feeling the prostate through the wall of the rectum or doing a blood test for prostate-specific antigen (psa). [icd10data.com]

  These treatments also may reduce chronic low back pain, joint pain, headaches, and pain from cancer treatments. Before you try a complementary therapy, talk to your doctor about the possible value and potential side effects. [northshore.org]

• Enlargement of the Prostate

  The symptoms of benign prostatic hyperplasia or of other problems in the prostate may be like symptoms of prostate cancer. Enlarge Normal prostate and benign prostatic hyperplasia (BPH). [cancer.gov]

  Prostate problems definition and facts* Common prostate problems are prostatitis, enlarged prostate, and prostate cancer. [medicinenet.com]

  Those symptoms also may be caused by something other than prostate cancer, such as an enlarged-but-noncancerous prostate gland. [livescience.com]

• Prostatic Disease

  […] stage IV prostate cancer recurrent prostate cancer Additional relevant MeSH terms: Layout table for MeSH terms Prostatic Neoplasms Genital Neoplasms, Male Urogenital Neoplasms Neoplasms by Site Neoplasms Genital Diseases, Male Prostatic Diseases Carboplatin [clinicaltrials.gov]

  First, your doctor or continence advisor will want to look for the causes of your poor bladder control, such as prostate disease, infection, diabetes or some medicines. [continence.org.au]

  Serum prostate-specific antigen (PSA) levels are used as a marker for prostatic diseases, including BPH. Imaging studies can help confirm prostate size. [riaendovascular.com]

  I will remain on an aggressive prostate cancer treatment regimen and in the process reduce my risk for virtually every other age-related disease. [lifeextension.com]

• Urinary Retention

  Case Report A 67-year-old gentleman presented for the first time with acute urinary retention and left leg swelling. The urinary retention was managed by a urinary catheter. [hindawi.com]

  Another uncommon but dangerous complication is urinary retention—the inability to pass urine caused by an infection. Seek care immediately if you stop being able to urinate after a biopsy. [health.harvard.edu]

  Adverse effects of EBRT include cystitis, proctitis, enteritis, impotence, urinary retention, and incontinence. [emedicine.medscape.com]

  Systematic review and meta-analysis on management of acute urinary retention. Prostate Cancer Prostatic Dis. 2015 Dec;18(4):297–302. Yossepowitch O, Briganti A, Eastham JA, Epstein J, Graefen M, Montironi R, et al. [prostatecanceruk.org]

  Hospitalisation (usually for urinary infections) or urinary retention occur in less than 1% of cases. [healthengine.com.au]

• Pelvic Pain

  Examples of these symptoms include: back, hip, or pelvic pain blood in the urine or semen burning or pain upon urination difficulty fully emptying the bladder difficulty starting a stream of urine experiencing sudden urge to urinate a weak urine stream [medicalnewstoday.com]

  Chronic prostatitis, also called Chronic Pelvic Pain Syndrome (CPPS), is a common prostate problem. It can cause pain in the lower back, in the groin area, or at the tip of the penis. Men with this problem often have painful ejaculation. [medicinenet.com]

  Men with prostate cancer may have their presentation masked with overlying benign prostate hyperplasia (such as urinary urgency/frequency, weak stream, and incomplete voiding), others may have dysuria, UTIs, or pelvic pain. [cancertherapyadvisor.com]

• Urinary Hesitancy

  Symptoms associated with BPH include frequent urination and urinary hesitancy that can be especially troublesome at night (Gharaee-Kermani 2013). [lifeextension.com]

Pulmonary embolism was ruled out after blood workup and imaging investigations. Nevertheless, his chest X-ray showed left sided chest mass (Figure 1). [hindawi.com]

The patient was admitted for further workup. A brain MRI demonstrated metastatic involvement of the cavernous sinus (Figures 3, 4). [touchoncology.com]

What Is Prostate Cancer Workup? If cancer is present on biopsy, workup for metastasis may be indicated. Imaging studies may reveal the size and location of the tumor in the prostate as well as the extent of spread of the disease. [emedicinehealth.com]

In addition, a keen understanding of hereditary cancer syndromes and the indications for their workup is important, as it guides selection for NGS and referral for genetics counselling. References: Oros KK, Ghadirian P, Greenwood CM, et al. [targetedonc.com]

The USPSTF recommends against PSA screening in men aged 70 and older (grade D recommendation). [3] See Workup for more detail. [emedicine.medscape.com]

• Pericardial Effusion

  effusions Ascites CNS lesions Leptomeningeal disease Irradiated lesions unless progression documented after radiotherapy Documented progressive systemic disease despite at least 1 endocrine manipulation with either orchiectomy or LHRH agonist (which [clinicaltrials.gov]

Treatments that “target” cancer cells may offer the advantage of reduced treatment-related side effects and improved outcomes. [vacancer.com]

If the patients received some local therapy, it might improve the prognosis of some patients. [onlinelibrary.wiley.com]

Prognosis Prognosis means the expected outcome of a disease. In general, the prognosis is better when prostate cancer is diagnosed while it is localised and at a lower grade. You may wish to discuss your prognosis with your specialist. [cancercouncil.com.au]

Long-Term Prognosis Because most prostate cancers are diagnosed with early screening measures and are curable, the average long-term prognosis for prostate cancer is quite encouraging. [hopkinsmedicine.org]

CSS has a multitude of etiologies. [touchoncology.com]

Use Additional Use Additional Help Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10data.com]

Walsh PC, Donker PJ: Impotence following radical prostatectomy: Insight into etiology and prevention. J Urol 128:492-497, 1982. 3. [cancernetwork.com]

Environmental factors, notably diet, are also important (see Etiology). Currently, the majority of prostate cancers are identified in patients who are asymptomatic. [emedicine.medscape.com]

EpiCast Report: Prostate Cancer – Epidemiology Forecast to 2028, to be published Latest reports from GlobalData is this website’s parent business intelligence company. [pharmaceutical-technology.com]

An interesting study based out of the Australian Oncology Radiology Department, Northern Sydney Cancer Centre, conducted a very thorough epidemiological meta-analysis, completed in 2003 and published in 2004. [naturalnews.com]

To determine the accurate age-adjusted incidence of prostate small cell carcinoma (SCC), update the clinical and pathological characteristics, as well as survival data of prostate SCC from Surveillance, Epidemiology, and End Results (SEER) datasets. [urotoday.com]

The American Cancer Society relies on information from the SEER (Surveillance, Epidemiology, and End Results) database, maintained by the National Cancer Institute (NCI), to provide survival statistics for different types of cancer. [cancer.org]

Keywords Acknowledgments SEER Citation: Surveillance, Epidemiology, and End Results (SEER) Program (www.seer.cancer.gov) SEER*Stat Database: Incidence - SEER 17 Regs Limited-Use + Hurricane Katrina Impacted Louisiana Cases, Nov 2007 Sub (1973–2005 varying [auajournals.org]

Pathophysiology and Contributing Factors in Postprostatectomy Incontinence: A Review. Eur Urol. 2017 Jun;71(6):936–44. Hefermehl L, Bossert K, Ramakrishnan VM, Seifert B, Lehmann K. [prostatecanceruk.org]

Pathophysiology Prostate cancer develops when the rates of cell division and cell death are no longer equal, leading to uncontrolled tumor growth. [emedicine.medscape.com]

Xgeva (denosumab) Works to prevent or delay problems like fractures and is given as an injection under the skin every four weeks. [zerocancer.org]

Can you prevent prostate cancer? There's no sure way to prevent prostate cancer, but as with most diseases, maintaining a healthy lifestyle is the best way to lower the risk of getting it, according to the ACS. [livescience.com]

Details of how to improve your diet and what steps to undertake can be found in my book: Healthy Prostate: The Extensive Guide to Prevent and Heal Prostate Problems. [naturalprostate.com]

The protocol provides comprehensive approaches for the prevention of prostate cancer, including a comprehensive overview demonstrating the prostate cancer prevention benefits in response to Avodart® and finasteride. [lifeextension.com]

For example, drugs can be given to help prevent or reduce nausea and vomiting. Along with the risks above, some side effects are seen more often with certain chemo drugs. [cancer.org]