There were several limitations to the present study. [onlinelibrary.wiley.com]

PURPOSE: In the prostate specific antigen era most prostate cancer presents at an early stage. However, a significant number of patients have advanced disease, including those with stage IV disease. [ncbi.nlm.nih.gov]

This analysis presents relative survival estimates by RD-stage at diagnosis calculated using the cohort method for the period 2011–2016. [ncci.canceraustralia.gov.au]

[…] to more than half of one lobe, but is not in both lobes T2c: the tumor is present in both lobes of the prostate T3: the tumor has grown outside of the prostate and may be present in the seminal vesicles T3a: the tumor is outside of the prostate, but [zerocancer.org]

Our patient presented with mediastinal mass as the first manifestation of prostate cancer. Unusual prostate carcinoma metastases are usually encountered in the presence of known advanced disease but rarely as the first presentation. [hindawi.com]

• Chills

  Six appointments Therapy can be completed in a little over a month with only 6 appointments Generally well tolerated safety profile The most common side effects in clinical studies were chills, fatigue, fever, back pain, nausea, joint ache, and headache [provenge.com]

  The main side effects reported were chills, fever, and headache. 11 Treatment of Bone Complications Patients with advanced prostate cancer can have cancer cells that have spread to their bones, called bone metastases. [vacancer.com]

  The main side effects reported were chills, fever, and headache.11 Treatment of Bone Complications Patients with advanced prostate cancer can have cancer cells that have spread to their bones, called bone metastases. [texasoncology.com]

• Weight Loss

  If the prostate cancer has spread, become more severe and moved to a stage 4 then you might also experience the following symptoms: Bone pain, especially around the hips, thighs and lower back Swelling of the feet and legs Weight loss Fatigue Read what [naturalprostate.com]

  Bone pain, weight loss, swelling in the legs and feet, pelvic discomfort, erectile problems, trouble urinating, and blood in the urine and/or semen are common signs of advanced prostate cancer. [healthmonitor.com]

  Side effects include nausea, loss of appetite, and weight loss. Immunotherapy Sipuleucel-T (Provenge) is a vaccine doctors use to treat advanced prostate cancer, especially if it’s not responding to hormone therapy. [healthline.com]

  Weight loss. Swelling in your legs and feet. How is prostate cancer diagnosed? A blood test called a prostate-specific antigen (PSA) test is the most common way to check for prostate cancer. [northshore.org]

  More widespread disease often spreads to the bones and gives pain or unexplained weight loss and fatigue. [cancer.org.au]

• Abdominal Pain

  Contact your doctor immediately if you experience any of the following symptoms: abdominal pain, abdominal bloating, shortness of breath, dizziness, light-headedness and/or any signs of confusion In women, the most common side effects are those resulting [aboutzoladex.com]

  Green showed in her study that most common initial symptoms or findings for gastric metastasis from solid tumors were diffuse abdominal pain, nausea and vomiting, anorexia, guaiac-positive stool, and gastrointestinal bleeding, respectively [9]. [hindawi.com]

  Once the symptomatic, including obstructive, neurological or systemic symptoms like paracancerous syndrome, bone pain, hydronephrosis, abdominal pain, bloody stools, tumor has usually already evolved to a terminal stage.2-4 Thus, the prognosis of patients [onlinelibrary.wiley.com]

• Bone Pain

  If the prostate cancer has spread, become more severe and moved to a stage 4 then you might also experience the following symptoms: Bone pain, especially around the hips, thighs and lower back Swelling of the feet and legs Weight loss Fatigue Read what [naturalprostate.com]

  Bone pain, weight loss, swelling in the legs and feet, pelvic discomfort, erectile problems, trouble urinating, and blood in the urine and/or semen are common signs of advanced prostate cancer. [healthmonitor.com]

  Bone Pain Treatment The bones are a common place for prostate cancer to spread. Androgen deprivation therapy can often control the cancer that has spread to bones. [prostatecentre.com]

  Once the cells settle in the bone, they start to interfere with the bone’s normal health and strength, often leading to bone pain, fracture, or other complications that can significantly impair a man’s health. [pcf.org]

• Back Pain

  The story so far : he was diagnosed right-off-the-bat as Stage IV prostate cancer about six months ago, after spending the previous few months complaining of upper-back pain. [boards.straightdope.com]

  Six appointments Therapy can be completed in a little over a month with only 6 appointments Generally well tolerated safety profile The most common side effects in clinical studies were chills, fatigue, fever, back pain, nausea, joint ache, and headache [provenge.com]

  Side effects may include: nausea a headache back pain joint pain Surgery While some surgery to remove tumors may be an option, your doctor is less likely to recommend it for prostate cancer that has spread to multiple areas. [healthline.com]

  pain (from metastatic spread to the spine) Clinical scores that may be useful in assessing symptoms severity include: IPSS: international prostate symptoms score, 35 points score mainly assessing urinary symptoms IIEF: international index of erectile [radiopaedia.org]

  Case Report A 69-year-old man was presented with our hospital in October 2007, with four-month history of anorexia, painless gross hematuria, and back pain. [hindawi.com]

• Low Back Pain

  back pain pain with ejaculation your doctor will diagnose prostate cancer by feeling the prostate through the wall of the rectum or doing a blood test for prostate-specific antigen (psa). [icd10data.com]

  These treatments also may reduce chronic low back pain, joint pain, headaches, and pain from cancer treatments. Before you try a complementary therapy, talk to your doctor about the possible value and potential side effects. [northshore.org]

• Enlargement of the Prostate

  Enlarge Normal prostate and benign prostatic hyperplasia (BPH). A normal prostate does not block the flow of urine from the bladder. An enlarged prostate presses on the bladder and urethra and blocks the flow of urine. [cancer.gov]

  Those symptoms also may be caused by something other than prostate cancer, such as an enlarged-but-noncancerous prostate gland. [livescience.com]

• Urinary Retention

  Case Report A 67-year-old gentleman presented for the first time with acute urinary retention and left leg swelling. The urinary retention was managed by a urinary catheter. [hindawi.com]

  Another uncommon but dangerous complication is urinary retention—the inability to pass urine caused by an infection. Seek care immediately if you stop being able to urinate after a biopsy. [health.harvard.edu]

  Adverse effects of EBRT include cystitis, proctitis, enteritis, impotence, urinary retention, and incontinence. [emedicine.medscape.com]

  Systematic review and meta-analysis on management of acute urinary retention. Prostate Cancer Prostatic Dis. 2015 Dec;18(4):297–302. Yossepowitch O, Briganti A, Eastham JA, Epstein J, Graefen M, Montironi R, et al. [prostatecanceruk.org]

  Hospitalisation (usually for urinary infections) or urinary retention occur in less than 1% of cases. [healthengine.com.au]

• Prostatic Disease

  Diseases Carboplatin Docetaxel Estramustine Antineoplastic Agents Tubulin Modulators Antimitotic Agents Mitosis Modulators Molecular Mechanisms of Pharmacological Action Antineoplastic Agents, Alkylating Alkylating Agents Antineoplastic Agents, Hormonal [clinicaltrials.gov]

  First, your doctor or continence advisor will want to look for the causes of your poor bladder control, such as prostate disease, infection, diabetes or some medicines. [continence.org.au]

  Serum prostate-specific antigen (PSA) levels are used as a marker for prostatic diseases, including BPH. Imaging studies can help confirm prostate size. [riaendovascular.com]

  What happens in the aging man’s body, however, is that testosterone converts to estrogen and DHT, and these two testosterone metabolites have been shown to be involved in benign and malignant prostate disease. [lifeextension.com]

• Pelvic Pain

  Examples of these symptoms include: back, hip, or pelvic pain blood in the urine or semen burning or pain upon urination difficulty fully emptying the bladder difficulty starting a stream of urine experiencing sudden urge to urinate a weak urine stream [medicalnewstoday.com]

  Chronic prostatitis, also called Chronic Pelvic Pain Syndrome (CPPS), is a common prostate problem. It can cause pain in the lower back, in the groin area, or at the tip of the penis. Men with this problem often have painful ejaculation. [medicinenet.com]

  Men with prostate cancer may have their presentation masked with overlying benign prostate hyperplasia (such as urinary urgency/frequency, weak stream, and incomplete voiding), others may have dysuria, UTIs, or pelvic pain. [cancertherapyadvisor.com]

• Urinary Hesitancy

  Symptoms associated with BPH include frequent urination and urinary hesitancy that can be especially troublesome at night (Gharaee-Kermani 2013). [lifeextension.com]

Pulmonary embolism was ruled out after blood workup and imaging investigations. Nevertheless, his chest X-ray showed left sided chest mass (Figure 1). [hindawi.com]

The patient was admitted for further workup. A brain MRI demonstrated metastatic involvement of the cavernous sinus (Figures 3, 4). [touchoncology.com]

What Is Prostate Cancer Workup? If cancer is present on biopsy, workup for metastasis may be indicated. Imaging studies may reveal the size and location of the tumor in the prostate as well as the extent of spread of the disease. [emedicinehealth.com]

In addition, a keen understanding of hereditary cancer syndromes and the indications for their workup is important, as it guides selection for NGS and referral for genetics counselling. References: Oros KK, Ghadirian P, Greenwood CM, et al. [targetedonc.com]

Laboratory Studies In cases of suspected advanced prostate cancer, the hematologic workup should include a complete blood count (CBC), liver function tests (LFTs), and a chemistry profile, including levels of serum creatinine, acid and alkaline phosphatase [emedicine.medscape.com]

• Pericardial Effusion

  effusions Ascites CNS lesions Leptomeningeal disease Irradiated lesions unless progression documented after radiotherapy Documented progressive systemic disease despite at least 1 endocrine manipulation with either orchiectomy or LHRH agonist (which [clinicaltrials.gov]

Treatments that “target” cancer cells may offer the advantage of reduced treatment-related side effects and improved outcomes. [vacancer.com]

Treatment decisions in advanced cancer are difficult. The uncertain benefits of systemic anticancer treatment must be weighed against likely toxicity, in a situation where the goal of treatment is not cure. [answers.google.com]

If the patients received some local therapy, it might improve the prognosis of some patients. [onlinelibrary.wiley.com]

Staging helps a physician make an informed decision about treatment and provides information for a more reliable prognosis ( the likely course of this disease ). [whathealth.com]

Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment Tagged: advanced, Management, mortality, prognosis, survival [prostatecancerinfolink.net]

Prostate cancer prognosis and survival rates can help give patients an idea of their chances of surviving the disease based on the stage and time of diagnosis. While some patients may find this information helpful, others may not want to know. [protons.com]

Prognosis Prognosis means the expected outcome of a disease. In general, the prognosis is better when prostate cancer is diagnosed while it is localised and at a lower grade. You may wish to discuss your prognosis with your specialist. [cancercouncil.com.au]

CSS has a multitude of etiologies. [touchoncology.com]

Use Additional Use Additional Help Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10data.com]

Walsh PC, Donker PJ: Impotence following radical prostatectomy: Insight into etiology and prevention. J Urol 128:492-497, 1982. 3. [cancernetwork.com]

EpiCast Report: Prostate Cancer – Epidemiology Forecast to 2028, to be published Latest reports from GlobalData is this website’s parent business intelligence company. [pharmaceutical-technology.com]

An interesting study based out of the Australian Oncology Radiology Department, Northern Sydney Cancer Centre, conducted a very thorough epidemiological meta-analysis, completed in 2003 and published in 2004. [naturalnews.com]

Keywords Acknowledgments SEER Citation: Surveillance, Epidemiology, and End Results (SEER) Program (www.seer.cancer.gov) SEER*Stat Database: Incidence - SEER 17 Regs Limited-Use Hurricane Katrina Impacted Louisiana Cases, Nov 2007 Sub (1973–2005 varying [auajournals.org]

Muralidhar et al. used data from the Surveillance, Epidemiology, and End Results (SEER) database to identify men initially diagnosed with AJCC Stage IV prostate cancer between 1973 and 2011 and treated with. [prostatecancerinfolink.net]

Clinical requirements for prognostic precision differ from epidemiological requirements for comparability and statistical completeness.4 Specifically, the collection of RD-stage is intended for epidemiological population-based analyses only – in particular [ncci.canceraustralia.gov.au]

Pathophysiology and Contributing Factors in Postprostatectomy Incontinence: A Review. Eur Urol. 2017 Jun;71(6):936–44. Hefermehl L, Bossert K, Ramakrishnan VM, Seifert B, Lehmann K. [prostatecanceruk.org]

Details of how to improve your diet and what steps to undertake can be found in my book: Healthy Prostate: The Extensive Guide to Prevent and Heal Prostate Problems. [naturalprostate.com]

ZERO — The End of Prostate Cancer recently chalked major advocacy successes, increasing the amount of funding for the Prostate Cancer Research Program (PCRP) by 10 million per year, and pressing the United States Preventative Services Task Force (USPSTF [themighty.com]

Randomized controlled trial of zoledronic acid to prevent bone loss in men receiving androgen deprivation therapy for nonmetastatic prostate cancer. Journal of Urology 2003; 169:2008-2012. 15 Smith MR, Saad F, Coleman R et al. [vacancer.com]