Presentation
Decreased serum complement was present in 60%. Increased serum IgA was noted in 75%. The mean peak serum creatinine was 5.1 mg/dL, and 20% required acute dialysis. [ncbi.nlm.nih.gov]
Coagulase-negative staphylococci tend to be less pathogenic unless a foreign body (eg, intravascular catheter) is present. Epidemiology Many neonates are colonized with S aureus within the first postnatal week. [pedsinreview.aappublications.org]
Entire Body System
- Fever
You may also have chills and a fever. Endocarditis causes some flu-like symptoms: fever, chills, and fatigue. It also causes symptoms such as rapid heartbeat, shortness of breath, and fluid buildup in your arms or legs. [nlm.nih.gov]
A fever and low blood pressure are signs of septicemia. [mayoclinic.org]
Symptoms usually include : Pain in cheeks, teeth, or forehead Blocked nose, changed smell, sticky greenish nose discharge, bad breath and, rarely, fever High fever, facial swelling, severe headache, neck stiffness and confusion in severe sinusitis. [healthhype.com]
It causes a high fever, a dramatic drop in blood pressure (shock), dizziness and confusion. Septic arthritis: a condition where a joint becomes infected with Staphylococcus aureus bacteria causing joint swelling, pain and fever. [yourgenome.org]
- Wound Infection
S aureus is the most common cause of pyogenic infection of the skin; it also may cause osteomyelitis, septic arthritis, wound infection, abscess, pneumonia, empyema, endocarditis, pericarditis, meningitis, and toxin-mediated diseases, including food poisoning [pedsinreview.aappublications.org]
In 1881, Scottish surgeon Sir Alexander Ogston discovered and named the primary cause of wound infection " Staphylococcus ." Until this time, no one knew what exactly was causing wounds to become infected. [health.howstuffworks.com]
Infections of Burns and Surgical Wound: Burns and surgical wounds may become infected with S. aureus from the patient’s own nasal carriage or from medical personnel. [histopathology-india.net]
Signs and symptoms of staph infection If your child has a staph infection of an existing or new wound, they may have: swelling around the wound a wound that fails to completely heal a fever redness and heat around the wound yellow-coloured crusting (scabs [rch.org.au]
- Burning Pain
The most common symptom of bacterial urinary infection is a burning pain felt during urination and frequent urination. [rmhealthy.com]
Common symptoms are: Burning pain during urination, urinary frequency and urgency. Symptoms of bacterial prostatitis : Pain in the groin, testicles, penis or lower abdomen Cloudy urine, rarely blood in the semen Fever and muscular pain. [healthhype.com]
- Recurrent Bacterial Infection
Recurrent bacterial infections in the patient described are probably related to defective chemotaxis. [ncbi.nlm.nih.gov]
Raised serum IgE levels and defective neutrophil chemotaxis in three children with eczema and recurrent bacterial infections. Lancet 1 : 183-187. [ Links ] Joubert JR, Van-Schalkwyk DJ, Turner KJ 1980. [scielo.br]
- Malaise
The symptoms associated with cellulitis can evolve and worsen due to systemic bacterial migration via the bloodstream, and include fever, malaise, and chills. [hardinmd.lib.uiowa.edu]
Respiratoric
- Sore Throat
Some symptoms of Streptococcus include: fever, sore throat and swollen lymph nodes, red & weeping skin sores, rash, dizziness and confusion. [mrsaidblog.com]
The presence of yellow to green mucus in the nasal discharge and throat is an indication of an active immune response. Other symptoms are nasal congestion or stuffy nose, sore throat, cough, fever and pain of the nasal membranes. [livestrong.com]
TOXIC SHOCK Toxic shock syndrome is a life-threatening infection characterized by severe headache, sore throat, fever as high as 105°F (40.5°C), and a sunburn-like rash that spreads from the face to the rest of the body. Symptoms appear suddenly. [healthofchildren.com]
Toxic shock syndrome is a life-threatening infection characterized by severe headache, sore throat, fever as high as 105°F, and a sunburn-like rash that spreads from the face to the rest of the body. [medical-dictionary.thefreedictionary.com]
- Common Cold
[…] sneezing, common colds, allergies, and Staphylococcus aureus dispersion. J Infect Dis. 2006 Oct 15. 194(8):1119-26. [Medline]. Diep BA, Chambers HF, Graber CJ, et al. [emedicine.medscape.com]
- Nasal Discharge
The presence of yellow to green mucus in the nasal discharge and throat is an indication of an active immune response. Other symptoms are nasal congestion or stuffy nose, sore throat, cough, fever and pain of the nasal membranes. [livestrong.com]
Gastrointestinal
- Nausea
Normally, this illness has a quick onset time and is accompanied by nausea, vomiting, diarrhea, fever, muscle aches, and even low blood pressure and death in severe cases. [fitnesshealth101.com]
It usually develops suddenly with: A high fever Nausea and vomiting A rash on your palms and soles that resembles sunburn Confusion Muscle aches Diarrhea Abdominal pain Septic arthritis Septic arthritis is often caused by a staph infection. [mayoclinic.org]
Incubation Period 1-6 hours Symptoms Nausea, vomiting, diarrhea, loss of appetite, severe abdominal cramps, mild fever Duration of Illness 24-48 hours What Do I Do? Drink plenty of fluids and get rest. [foodsafety.gov]
Common symptoms include: abdominal cramps nausea vomiting In some cases, these symptoms are followed by diarrhoea. The symptoms of staphylococcal food poisoning usually pass within 24 hours. [hse.ie]
- Abdominal Cramps
Incubation Period 1-6 hours Symptoms Nausea, vomiting, diarrhea, loss of appetite, severe abdominal cramps, mild fever Duration of Illness 24-48 hours What Do I Do? Drink plenty of fluids and get rest. [foodsafety.gov]
Diarrhea, with or without abdominal cramping, may be a flu-like symptom caused by a bacterial infection, particularly infections caused by spoiled or unclean food. [livestrong.com]
Food poisoning is characterized by symptoms like: Vomiting Nausea Dehydration Diarrhea Sweating Fatigue Abdominal Cramps These symptoms normally begin six to ten hours after eating infected food. [fitnesshealth101.com]
Common symptoms include: abdominal cramps nausea vomiting In some cases, these symptoms are followed by diarrhoea. The symptoms of staphylococcal food poisoning usually pass within 24 hours. [hse.ie]
- Flatulence
Blood Circulation Improve Digestion: Can help with colic, vomiting, and flatulence. [greenmedinfo.com]
Musculoskeletal
- Arthritis
Acute and Chronic Bacterial Arthritis: S. aureus is the causative organism in half of all cases of septic arthritis. Most of those who have the disease are adults, 50 to 70 years old, and usually only a single joint is involved. [histopathology-india.net]
Acute renal failure developed in a diabetic with staphylococcal arthritis and septicaemia in the absence of endocarditis. Renal biopsy showed proliferative glomerulonephritis and there was evidence of alternative pathway of complement activation. [ncbi.nlm.nih.gov]
[…] and may appear as: Skin infection Infection of the mucous membranes (sinusitis, epiglottitis, vaginitis) Infection of the glands (mastitis, parotitis) Staph food poisoning Urinary infection in men Bone infection (osteomyelitis) and joint infection (arthritis [healthhype.com]
We will delve into Staphylococcus aureus, MRSA, septic arthritis, toxic shock syndrome, and antibiotic resistance. [study.com]
Skin
- Eczema
Hyper IgE syndrome (HIES) is a rare primary immunodeficiency disorder, characterized by eczema, recurrent skin and lung infections, and significantly elevated serum IgE level. [ncbi.nlm.nih.gov]
Suspected involvement in atopic dermatitis (eczema), including related clinical trials. The main coagulase-positive staphylococcus is Staphylococcus aureus, although not all strains of Staphylococcus aureus are coagulase positive. [en.wikipedia.org]
If your child has eczema, an affected area of skin may become infected with staph. Staph can cause other kinds of illnesses including bone infections, impetigo (school sores), pneumonia and blood stream infections. [rch.org.au]
Medication with systemic steroids, retinoids, cytotoxics or immunosuppressives Immunoglobulin M deficiency Chronic granulomatous disease Chediak-Higashi syndrome Job and Wiskott Aldrich syndromes (associations of severe staphylococcal infection with eczema [dermnetnz.org]
- Erythema
Note the periorbital swelling and erythema. The symptoms associated with cellulitis can evolve and worsen due to systemic bacterial migration via the bloodstream, and include fever, malaise, and chills. [hardinmd.lib.uiowa.edu]
Characteristic findings on physical examination Physical findings are varied and include erythema, edema, and warmth of the skin, in the case of cutaneous abscesses; follicular papules and pustules in the setting of furunculosis and folliculitis, respectively [clinicaladvisor.com]
Diagnosis Examination in patients with staphylococcal infections may include the following findings: Skin and soft-tissue infections: Erythema, warmth, draining sinus tracts, superficial abscesses, bullous impetigo Toxic shock syndrome: Fever higher than [emedicine.medscape.com]
A tunneled (i.e., Hickman catheter) or implantable device should be removed if there is purulence or erythema at the exit site or along the tunnel, evidence of pocket infection, or if it is associated with a complicated deep-seated infection. [aafp.org]
- Eruptions
A severe and potentially fatal variant of the disease, Staphylococcal scalded skin syndrome, occurs in infants, which is characterized by the development of a generalized bullous eruption. [apps.who.int]
And Redness Discharge From The Penis Low Sperm Count Scalded Skin Syndrome Hydrocele Testicular Disorders Hydrosalpinx Skin Disease Abscesses and Boil Hydrosalpinx Abnormal Growth In Breast Tissue Dead Sperm Counts Difficulty Becoming Pregnant Skin Eruptions [dollyhamshealth.com]
- Pruritus
A man who was suffering from recurrent staphylococcal infection had antecedent symptoms of severe pruritus. [ncbi.nlm.nih.gov]
Pruritus is common and the infected area is often extended by scratching. [apps.who.int]
Urogenital
- Kidney Failure
Individuals with the following conditions are at greater risk: chronic steroid therapy, chemotherapy, malignancies, dialysis for kidney failure, AIDS, sickle cell disease, peripheral vascular disease, inflammatory bowel disease, and severe burns. [clinicaladvisor.com]
People who may be more likely to get a staph infection include those with: Diabetes who use insulin HIV/AIDS Kidney failure requiring dialysis Weakened immune systems — either from a disease or medications that suppress the immune system Cancer, especially [mayoclinic.org]
They include diabetics, nursing mothers, small babies and people with weak immune systems, respiratory illnesses, kidney failure requiring dialysis, cancer and other chronic diseases. [top10homeremedies.com]
Neurologic
- Headache
The headaches typically change intensity with position and disappear shortly after getting out of bed. [livestrong.com]
When a person has a headache, a cold, or the flu, most other people are able to understand to varying degrees what is wrong with them, as most other ailments are rather secular in their impact. [rmhealthy.com]
This Morning Alex Lewis, who appeared on This Morning today, was infected with Strep A bacteria ITV/This Morning Alex Lewis has previously appeared on This Morning When Alex Lewis fell ill in November 2013, Mr Lewis initially dismissed his crippling headaches [express.co.uk]
Symptoms are like in meningitis caused by other bacteria: Low grade fever Headache Lethargy Confusion Signs of meningeal irritation like neck stiffness are usually not present ( 9 ). [healthhype.com]
Workup
[…] immediate transesophageal echocardiography (TEE), when possible Transesophageal echocardiography (TEE): For all patients with catheter-related S aureus bacteremia (and no contraindications); for all patients with suspected S aureus endocarditis See Workup [emedicine.medscape.com]
Laboratory
- Leukocytosis
Laboratory investigations showed leukocytosis with eosinophilia, hyperimmunoglobulinemia of all fractions, but particularly of IgE, and a deficiency of cell-mediated immunity on in vivo testing. [ncbi.nlm.nih.gov]
bullous impetigo Toxic shock syndrome: Fever higher than 38.9°C (102.02°F), diffuse erythroderma, hypotension, desquamation Endocarditis: Regurgitant murmur, petechiae/cutaneous lesions, fever Laboratory testing Complete blood count: Usually shows leukocytosis [emedicine.medscape.com]
Treatment
There was no abnormal auditory brainstem response or serum creatinine change associated with ABK treatment. [ncbi.nlm.nih.gov]
1998, vol. 26 (pg. 66 - 75 ) 21 Open-label assessment of levofloxacin for the treatment of acute bacterial sinusitis in adults, Ann Allergy Asthma Immunol, 1998, vol. 80 (pg. 357 - 62 ) 22 Azithromycin versus amoxicillin/clavulanate in the treatment [doi.org]
Prognosis
Age and DM are independent risk factors of poor prognosis for glomerulonephritis related to staphylococcal infection. [ncbi.nlm.nih.gov]
Staph Infection Prognosis When mild and promptly treated with antibiotics, the prognosis for recovery from a Staph infection is excellent. However, a MRSA infection can have an entirely different outlook. [onhealth.com]
Prognosis Most healthy people who develop staph infections recover fully within a short time. Others develop repeated infections. Some become seriously ill, requiring long-term therapy or emergency care. A small percentage die. [healthofchildren.com]
Etiology
Etiology Pathophysiology S. aureus is a gram-positive organism which is both coagulase- and catalse-positive. The organisms provide a number of toxins ( Table I ), which are responsible for the clinical manifestations of disease. Table I. [clinicaladvisor.com]
Osteomyelitis: etiology, diagnosis, treatment and outcome in a public versus a private institution. Infection. 2001;29:333–6. 22. Bamberger DM. Diagnosis and treatment of osteomyelitis. Comp Ther. 2000;26:89–95. 23. [aafp.org]
Epidemiology
Epidemiology Many neonates are colonized with S aureus within the first postnatal week. Thereafter, up to 50% of healthy individuals carry at least one strain of S aureus in the anterior nares at any given time. [pedsinreview.aappublications.org]
The physician will be requested to send the isolate to CDC for microbiologic and epidemiologic evaluation. [cdc.gov]
Sponsored by the Armed Forces Epidemiology Board Commission of Streptococcal and Staphylococcal Disease and supported by the Surgeon General, United States Army, by a training grant (2E-9) with the National Institute of Allergy and Infectious Disease [nejm.org]
Therefore, a study was conducted to describe the epidemiologic, clinical, and economic outcomes of SI following these operations in France based on a hospital discharge database. [ncbi.nlm.nih.gov]
Pathophysiology
Systematic review of the literature revealed a few interesting cases of reactivated staphylococcal infection after decades of latency, although the exact pathophysiological mechanisms still need to be elucidated. [ncbi.nlm.nih.gov]
Etiology Pathophysiology S. aureus is a gram-positive organism which is both coagulase- and catalse-positive. The organisms provide a number of toxins ( Table I ), which are responsible for the clinical manifestations of disease. Table I. [clinicaladvisor.com]
Ringel-Kulka, Microbiota of the Gastrointestinal Tract in Infancy, The Microbiota in Gastrointestinal Pathophysiology, 10.1016/B978-0-12-804024-9.00003-3, (27-35), (2017). Wei-ping Zeng, Margaret M. [doi.org]
Genomewide analysis of gene expression in Staphylococcus epidermidis biofilms: insights into the pathophysiology of S. epidermidis biofilms and the role of phenol-soluble modulins in formation of biofilms. J. Infect. Dis. 191, 289–298 (2005). 21. [nature.com]
Prevention
In this article, effective procedures for the prevention of hospital-acquired staphylococcal infections are summarized, with special emphasis on cost-saving measures. [ncbi.nlm.nih.gov]
Strategies to Prevent Staphylococcal Infections Hand Washing is the Single Most Important Behavior in Preventing Infectious Disease The proper way to wash your hands: Use warm water. Wet your hands and wrists. Using a bar or liquid soap. [uiltexas.org]