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2.1
Staphylococcal Pneumonia
Pneumonia due to Staphylococcus

Presentation

Most of the patients presented comorbidities, of which diabetes mellitus was the most common. Twelve patients presented complications such as empyema and septic shock. Four patients died, translating to a mortality rate of 16.6% in our sample. [ncbi.nlm.nih.gov]

Two patients presented septic shock associated with AKI. [scielo.br]

Misleading presentation of staphylococcal pneumonia in an adolescent girl: a case report Abstract S. aureus is a relatively uncommon causative agent of community-acquired pneumonia. [jpnim.com]

Entire Body System

  • Fever

    Fever and signs of pleural effusion and respiratory distress were common in primary disease while fever and a toxic appearance were frequent with disseminated illness. [ncbi.nlm.nih.gov]

  • Pain

    The symptoms of staphylococcal pneumonia: the increase in body temperature; General malaise, chills, muscle weakness; may experience pain in the throat; cough, may be blood admixtures in sputum; pain in the sternum during coughing or deep breathing; severe [respiratory.vsebolezni.com]

    Osteomyelitis can be difficult to detect, but you may have it if you have: a temperature nausea severe bone pain red, warm tender skin at the site of the pain restricted movement of a joint Read more about osteomyelitis here. [healthdirect.gov.au]

    Chest Pain Chest pain occurs when pneumonia develops, as the lungs work harder to breathe. Additionally, chest muscles become sore from the persistent cough. [livestrong.com]

    We report a case of a 13-year-old girl without predisposing factors who was admitted with a recent history of mild chest pain, weakness and slight fever. [jpnim.com]

  • Chills

    This form is very hard, with fever and chills. There are severe pain in sternum, shortness of breath. Chest x-ray shows the infiltration of the pulmonary tissue. After the abscess burst into a bronchus. [respiratory.vsebolezni.com]

    You may have septic arthritis if you are experiencing: pain and swelling in your joint stiffness red and tender skin around the joint a temperature over 38°C chills a loss of movement in your joint Sepsis Sepsis is also known as blood poisoning. [healthdirect.gov.au]

    This results in the fever, chills, and fatigue common in bacterial and fungal pneumonia. The neutrophils, bacteria, and fluid leaked from surrounding blood vessels fill the alveoli and result in impaired oxygen transportation. [en.wikipedia.org]

    Chills may occur in response to the rise in body temperature, and hot flashes may occur in older persons or those with weakened immune systems in response to the decrease in body temperature. [livestrong.com]

  • Malaise

    Army Hospital, Landstuhl, on January 4, 1954, with the chief complaints of fever and malaise for three days. Aside from a mild chronic cough she had been well until January 1, when there was an onset of fatigue, chilliness and FULL TEXT [annals.org]

    […] fever, malaise, headache, sore throat Streptococcus pyogenes untreated pharyngitis, inflammation of heart valves, heart muscles, joints, and blood vessels and kidneys strawberry red tongue red rash that spreadsStrep pyogenes sore throat, malaise, headache [quizlet.com]

    The elderly may present with mainly systemic complaints of malaise, fatigue, anorexia and myalgia. Young children may present with nonspecific symptoms or abdominal pain. [patient.info]

  • Rigor

    Signs and symptoms [ edit ] Pneumonia Fever Rigors Cough Runny nose (either direct bacterial pneumonia or accompanied by primary viral pneumonia ) Dyspnea – shortness of breath Chest pain Shaking chills [2] Pneumococcal pneumonia can cause coughing up [en.wikipedia.org]

    Sweats, rigors and chills were reported by three, seven and six patients respectively. One patient described a preceding flu-like illness. Five patients, whose ages ranged from 57 to 88 years, were acutely confused at presentation. [nzma.org.nz]

    Initial mild headache and myalgia leading to high fever, chills and repeated rigors; non-chest symptoms often predominate early on. Cough is nearly always present, initially unproductive but may lead to expectoration later. [patient.info]

Respiratoric

  • Cough

    Cough If a persistent cough and wheezing occurs when infected with MRSA, then the staph infection has affected the lungs and caused pneumonia. Other distinguishing symptoms include a relentless and deep cough and shortness of breath, called dyspnea. [livestrong.com]

    The symptoms of staphylococcal pneumonia: the increase in body temperature; General malaise, chills, muscle weakness; may experience pain in the throat; cough, may be blood admixtures in sputum; pain in the sternum during coughing or deep breathing; severe [respiratory.vsebolezni.com]

    He had presented with cough for one month and respiratory difficulty for one-week duration and history of bilious vomiting two days prior to admission. [ncbi.nlm.nih.gov]

    Aside from a mild chronic cough she had been well until January 1, when there was an onset of fatigue, chilliness and FULL TEXT [annals.org]

  • Pleural Effusion

    So radiological finding of pleural effusion with displacement of mediastinum to the left and the presence of bowel gas high in the right upper quadrant should alert the possibility of a right-sided Bochdalek hernia. [ncbi.nlm.nih.gov]

    Consensual mild pleural effusion was documented by a chest radiograph (A) and high-resolution computed tomography (B). [es.slideshare.net]

  • Productive Cough

    The patient will present with an abrupt onset of fever, tachypnea, pleuritic chest pain, and a productive cough with purulent sputum, which can be blood-tinged. S. aureus is also one of the most common causes of empyema. [visualdx.com]

    Pain in the chest and dry or productive cough are present. Blood in sputum is always present in staph pneumonia. An abscess can also form with staph lung infection. Staphylococcus pneumonia is a serious complication of influenza. [simple-remedies.com]

    Chronic bronchitis / bronchiectasis (sequelae) Children with persistent symptoms and/or signs including chronic productive cough, persistent crackles, clubbing and/or x-ray findings should be evaluated further for possible underlying bronchitis/bronchiectasis [starship.org.nz]

  • Dyspnea

    Staphylococci cause necrotizing pneumonitis empyema, pneumatoceles, pyopneumothorax, bronchopleural fistulas diffuse interstitial disease characterized by extreme dyspnea, tachypnea, and cyanosis. Clinical Manifestations. [medicalpptonline.blogspot.com]

    Other distinguishing symptoms include a relentless and deep cough and shortness of breath, called dyspnea. Sometimes natural breathing rhythms bring on bouts of wheezing and coughing, especially when inhaling air or taking deep breaths. [livestrong.com]

    Signs and symptoms [ edit ] Pneumonia Fever Rigors Cough Runny nose (either direct bacterial pneumonia or accompanied by primary viral pneumonia ) Dyspnea – shortness of breath Chest pain Shaking chills [2] Pneumococcal pneumonia can cause coughing up [en.wikipedia.org]

    The most common symptoms are dyspnea, fever, cough and pleuritic chest pain accompanied by leukocytosis and bacteremia. (23) Hemoptysis, also observed by some authors, (8) is an uncommon finding. [scielo.br]

    On follow-up 1 year later, he showed residual dyspnea with heavy exertion but was working again full-time. Figure 1 Chest radiograph on admission showing bilateral dense infiltrates. [annalsofintensivecare.springeropen.com]

  • Tachypnea

    Results of physical examination may,, be misleading, in young infants, with findings disproportionate to the degree of tachypnea. Diagnosis. Recognizing early staphylococcal pneumonia in infants is often difficult. [medicalpptonline.blogspot.com]

    The patient will present with an abrupt onset of fever, tachypnea, pleuritic chest pain, and a productive cough with purulent sputum, which can be blood-tinged. S. aureus is also one of the most common causes of empyema. [visualdx.com]

    Characteristic features include fever and spasms of dry coughing, followed by marked tachypnea with expiratory grunting, sternal retraction, cyanosis, progressive lethargy, and shock. [histopathology-india.net]

Gastrointestinal

  • Abdominal Pain

    Inhalation pneumonia is caused by alterations of mucociliary clearance, leukocyte dysfunction, or bacterial adherence initiated by a viral infection. high fever, abdominal pain, tachypnea, dyspnea, localized or diffuse bronchopneumonia lobar disease. [medicalpptonline.blogspot.com]

    Young children may present with nonspecific symptoms or abdominal pain. Signs: tachypnoea, bronchial breathing, crepitations, pleural rub, dullness with percussion. [patient.info]

    Atypical presentations without obvious respiratory symptoms are not rare (abdominal pain and vomiting mimicking an acute abdomen, meningism mimicking meningitis). [starship.org.nz]

  • Bilious Vomiting

    He had presented with cough for one month and respiratory difficulty for one-week duration and history of bilious vomiting two days prior to admission. [ncbi.nlm.nih.gov]

Cardiovascular

  • Chest Pain

    Chest Pain Chest pain occurs when pneumonia develops, as the lungs work harder to breathe. Additionally, chest muscles become sore from the persistent cough. [livestrong.com]

    We report a case of a 13-year-old girl without predisposing factors who was admitted with a recent history of mild chest pain, weakness and slight fever. [jpnim.com]

    The patient will present with an abrupt onset of fever, tachypnea, pleuritic chest pain, and a productive cough with purulent sputum, which can be blood-tinged. S. aureus is also one of the most common causes of empyema. [visualdx.com]

    One person died at home suddenly; the other patients' presenting symptoms were cough with bloody sputum, fever, and pleuritic chest pain. Chest films showed extensive bilateral opacities. [pulmccm.org]

  • Cyanosis

    Staphylococci cause necrotizing pneumonitis empyema, pneumatoceles, pyopneumothorax, bronchopleural fistulas diffuse interstitial disease characterized by extreme dyspnea, tachypnea, and cyanosis. Clinical Manifestations. [medicalpptonline.blogspot.com]

    […] pneumonia: the increase in body temperature; General malaise, chills, muscle weakness; may experience pain in the throat; cough, may be blood admixtures in sputum; pain in the sternum during coughing or deep breathing; severe shortness of breath, wheezing; cyanosis [respiratory.vsebolezni.com]

    Characteristic features include fever and spasms of dry coughing, followed by marked tachypnea with expiratory grunting, sternal retraction, cyanosis, progressive lethargy, and shock. [histopathology-india.net]

  • Tachycardia

    On examination, he was febrile and had tachycardia (Pulse- 104/min) and tachypnoea (Resp- 34/min). Clinically, he had crepts in both lower lobes and right middle lobe with decreased breath sounds. [ijpmonline.org]

    The most important and distinctive clinical sign is bleeding from the respiratory tract and also hypotension, tachycardia (>140 beats/min), and digestive symptoms like nausea, vomiting, and diarrhea. [criticalcare.imedpub.com]

Musculoskeletal

  • Arthralgia

    Arthralgia and myalgia are often reported. Severe complications include pancreatitis, peritonitis, pericarditis, myocarditis, endocarditis and glomerulonephritis. Signs Vital signs should be checked. [patient.info]

    Mycoplasma pneumoniae should be suspected in school age children especially if the onset of symptoms is insidious and/or the child has wheeze, headache or arthralgia. [starship.org.nz]

    Other side effects are severe arthralgia and myalgia. Has a variety of drug-drug interactions mediated via the cytochrome P450 system. No dose adjustment is required for renal or hepatic insufficiency. [hopkinsguides.com]

Workup

[…] progress rapidly Pleural effusion, pneumatoceles, and pneumothorax are also common In oncology patients, S aureus may cause pulmonary nodules [7] Thrombophlebitis Obtain a blood culture through the intravenous line and a peripheral blood culture See Workup [emedicine.medscape.com]

X-Ray

  • Mediastinal Shift

    Reversal of the mediastinal shift and closure of the bronchopleural fistulae was achieved by assisted independent lung ventilation. [ncbi.nlm.nih.gov]

Microbiology

  • Gram-Positive Bacteria

    Etiology Staphylococcal pneumonia is caused by the Gram-positive bacteria Staphylococcus sp. S. aureus is responsible for most cases of staphylococcal bronchopneumonia. [radiologykey.com]

    Microscopic sections of the lungs demonstrated extensive necrotizing pneumonia with abscess formation, coagulative necrosis, destruction of lung parenchyma, and red blood cell extravasation with multiple foci of Gram-positive bacteria colonies seen in [nature.com]

    Most patients in our series had severe disease and received broad-spectrum antimicrobial drugs, including coverage for resistant gram-positive bacteria. [wwwnc.cdc.gov]

  • Blood Culture Positive

    Blood cultures were positive for S. aureus in 36% (n=12). [nzma.org.nz]

    Under these conditions, blood culture positivity tends to be higher, making blood culture an effective instrument in diagnosis. [scielo.br]

  • Staphylococcus Aureus in the Sputum

    or heavy growth of Staphylococcus aureus in cultured sputum or empyema fluid. [books.mcai.org.uk]

Pleura

  • Pleural Effusion

    So radiological finding of pleural effusion with displacement of mediastinum to the left and the presence of bowel gas high in the right upper quadrant should alert the possibility of a right-sided Bochdalek hernia. [ncbi.nlm.nih.gov]

    Consensual mild pleural effusion was documented by a chest radiograph (A) and high-resolution computed tomography (B). [es.slideshare.net]

  • Pleural Rub

    Signs: tachypnoea, bronchial breathing, crepitations, pleural rub, dullness with percussion. [patient.info]

Treatment

Treatment of this condition by closed intercostal catheter drainage was effective. Pneumatoceles were encountered, but resolved spontaneously. [ncbi.nlm.nih.gov]

Treatment of hospital-acquired pneumonia with linezolid or vancomycin: a systematic review and meta-analysis Source: Database of Abstracts of Reviews of Effects - DARE - 13 November 2013 Treatment of hospital-acquired pneumonia with linezolid or vancomycin [evidence.nhs.uk]

Only early recognition and prompt treatment can reduce the high mortality rate in this age group. [pediatrics.aappublications.org]

Prognosis

Treatment and prognosis Treatment depends on the underlying agent while prognosis depends on the severity of the pathogen as well as the susceptibility of the host. [radiopaedia.org]

Prognosis and outcomes of patients with community-acquired pneumonia. A meta-analysis. JAMA. 1996;275(2):134-41. [ Links ] 29. Gorak EJ, Yamada SM, Brown JD. [scielo.br]

Septic lesions outside the respiratory tract = pericarditis, meningitis, osteomyelitis, and metastatic abscesses in soft tissue Prognosis. mortality still ranges from 10-30% Factors = the length of illness before hospitalization age of the patient, adequacy [medicalpptonline.blogspot.com]

The prognosis for this form of the disease is usually favorable. After treatment recovery occurs, however, in the former destructions (cavities) can form air cysts. Staphylococcal infiltration is severe, with pronounced intoxication. [respiratory.vsebolezni.com]

Prognosis Mortality from CAP is less than 1% in those well enough to be managed in the community. [ 16 ] The mortality rate in patients admitted to hospital is 5-10% in those not requiring intensive care unit admission, as high as 25% in intubated patients [patient.info]

Etiology

Among patients with severe CAP, staphylococcal infection is one of the most common etiologies. It is a high-risk disease, even when it affects young or previously healthy patients. [scielo.br]

Staphylococcal etiology should be suspected in patients with acute pneumonia who have soft tissue infection or have characteristic chest roentgenogram findings; antistaphylococcal agents should be included in the therapeutic regimens of such patients [ncbi.nlm.nih.gov]

English : BL blood CF cerebrospinal fluid CI chemically induced CL classification CO complications CN congenital DI diagnosis DG diagnostic imaging DH diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology EH ethnology ET etiology [decs.bvs.br]

Etiology Staphylococcal pneumonia is caused by the Gram-positive bacteria Staphylococcus sp. S. aureus is responsible for most cases of staphylococcal bronchopneumonia. [radiologykey.com]

Epidemiology

This retrospective study of cases diagnosed over a 20 year period at a tertiary paediatric hospital was undertaken to document the epidemiology and assess the management and mortality of the disease. [ncbi.nlm.nih.gov]

68 Allowable Qualifiers English : BL blood CF cerebrospinal fluid CI chemically induced CL classification CO complications CN congenital DI diagnosis DG diagnostic imaging DH diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology [decs.bvs.br]

Epidemiology Many neonates are colonized with S aureus within the first postnatal week. Thereafter, up to 50% of healthy individuals carry at least one strain of S aureus in the anterior nares at any given time. [pedsinreview.aappublications.org]

Pathophysiology

[…] direct bacterial pneumonia or accompanied by primary viral pneumonia ) Dyspnea – shortness of breath Chest pain Shaking chills [2] Pneumococcal pneumonia can cause coughing up of blood, or hemoptysis, characteristically associated with "rusty" sputum [3] Pathophysiology [en.wikipedia.org]

This cytokine release mediates the TSS; the resultant pathophysiology mimics that of endotoxic shock. [emedicine.medscape.com]

Prevention

Recognition of this prevented inappropriate management. The patient also developed the toxic shock syndrome. In contrast to infants with pneumatoceles, recovery of lung function has been poor. [ncbi.nlm.nih.gov]

Centers for Disease Control and Prevention. Overview of Healthcare-associated MRSA. (Online information). Available online at http://www.cdc.gov/ncidod/dhqp/ar_mrsa.html. Accessed December 2007. Centers for Disease Control and Prevention. [labtestsonline.it]

[…] diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology EH ethnology ET etiology GE genetics HI history IM immunology ME metabolism MI microbiology MO mortality NU nursing PS parasitology PA pathology PP physiopathology PC prevention [decs.bvs.br]

Staph Infection in Lungs Treatment Process and Preventive Measures Preventive measures: it is very important to strengthen the immune system of the person especially in high risk groups. [simple-remedies.com]

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