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Staphylococcal Septicemia

Septicaemia Staphylococcal


Presentation

  • We present a report of three cases with vesicles containing opalescent fluid grouped over the face and scattered on the trunk and limbs. Culture of the fluid aspirated from the vesicles grew Staphylococcus aureus in two of the three cases.[ncbi.nlm.nih.gov]
  • [Rati Santhakumar, David Pudukadan, Johny Vincent, Baburaj Parameswaran] PMID 21906154 Abstract We present a report of three cases with vesicles containing opalescent fluid grouped over the face and scattered on the trunk and limbs.[sigmaaldrich.com]
  • Case A previously healthy 21-year-old woman presented at 26 weeks' gestation with staphylococcal sepsis of undetermined origin.[journals.lww.com]
Fever
  • Nephropathy, eosinophilia and fever were observed in an 18-year-old man being treated for staphylococcal septicemia. Parenteral challenge with suspected sensitizing agents confirmed methicillin as the likely offender.[ncbi.nlm.nih.gov]
  • Staphylococcal septicemia can cause sudden and severe symptoms including a high fever and chills, quickly beating heart, and fast breathing. Staphylococcal septicemia may also cause confusion and other changes in mental functioning.[healthetreatment.com]
  • Rocky Mountain spotted fever begins as a non-specific flu-like illness with fever, headache, and myalgia after an incubation period of 2 to 14 days (median 7 days) after a tick bite.[microbiologybook.org]
Flank Mass
  • Abstract Gross hematuria, a flank mass, and a nonfunctioning kidney were seen at excretory urography in a 10-month-old infant with staphylococcal pneumonia and septicemia.[ncbi.nlm.nih.gov]
Aspiration
  • Culture of the fluid aspirated from the vesicles grew Staphylococcus aureus in two of the three cases. The observation of vesicles grouped on the face in a sick febrile child should prompt the diagnosis of a severe staphylococcal septicemia.[ncbi.nlm.nih.gov]
  • Bone marrow aspirations were performed on 6 patients and all of them hadhemophagocytosis shown in bone marrow smears. Among 7 patients, 4 patientssurvived(57.14%) and 3 patients died(42.86%).[bloodjournal.org]
  • Gram-positive cocci are seen in aspirated tracheal or pleural fluid, which is often bloody.[histopathology-india.net]
  • Diagnosis Folliculitis, furuncle, and carbuncle Diagnosis based on clinical appearance Aspiration or incision and culture of purulent material from the lesion occasionally diagnostic Osteomyelitis Cultures of bone aspirate Blood culture results positive[emedicine.medscape.com]
Cardiomegaly
  • Posteroanterior chest radiograph of a 15-year-old with staphylococcal endocarditis and multiple septic emboli, revealing borderline cardiomegaly, multiple nodular infiltrates, and bilateral pleural effusions.[emedicine.medscape.com]
Hepatosplenomegaly
  • Typical clinical symptoms included pneumonia (63%), gastrointestinal disorders (56%, NEC in 7 cases), shock (32%) jaundice and hepatosplenomegaly (38%), purulent meningitis (18%).[unepsa.org]
Janeway Lesion
  • The latter include splinter hemorrhages, pustular purpura, petechiae (typically found in the conjunctivae, buccal mucosa, palate, or extremities, Janeway lesions (hemorrhagic, painless plaques usually found on the palms or soles), and Osler nodes (small[microbiologybook.org]
Quadriplegia
  • On postburn day 50, quadriplegia developed. Magnetic resonance imaging revealed an anterior cervical mass, and cervical drainage of a staphylococcal cervical abscess was conducted. Antibiotics were continued.[ncbi.nlm.nih.gov]

Workup

  • […] disease, an ID consult was associated with a 56% reduction in 28-day mortality. 24 The patients who were followed by an ID consult service were more likely to receive appropriate duration of antibiotics (81% vs. 29%, respectively) and undergo appropriate workup[the-hospitalist.org]
  • […] progress rapidly Pleural effusion, pneumatoceles, and pneumothorax are also common In oncology patients, S aureus may cause pulmonary nodules [7] Thrombophlebitis Obtain a blood culture through the intravenous line and a peripheral blood culture See Workup[emedicine.medscape.com]
Gram-Positive Bacteria
  • From Wikipedia, the free encyclopedia Jump to navigation Jump to search The Bacillales are an order of Gram-positive bacteria, placed within the Firmicutes. [1] Representative genera include Bacillus, Listeria and Staphylococcus. [2] References [ edit[en.wikipedia.org]
  • Gram positive bacteria were shown to be the most frequent cause of sepsis in the US in a 2003 study (see epidemiology section).[atsu.edu]
  • Skin lesions in sepsis can arise by at least 5 mechanisms: Disseminated intravascular coagulation and coagulopathy - for example, in sepsis due to gram-negative and gram-positive bacteria.[microbiologybook.org]
  • Linezolid is a bacteriostatic oxazolidin that has high oral bioavailability and inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit in Gram-positive bacteria and mycobacterial species ( 122 , 123 ).[cjasn.asnjournals.org]

Treatment

  • These two cases emphasize the importance of clinical and microbiological monitoring of patients with staphylococcal septicemia, even when glycopeptides are used for treatment.[ncbi.nlm.nih.gov]
  • Most effective Staphylococcal Septicemia treatments reported by our membersLogin to add your rating How effective? How common? Description No treatments have been listed[healthetreatment.com]
  • II Department of Pediatrics, NICU, Zabrze, Poland OBJECTIVE: To determine the morbidity rate, clinical symptoms, biochemical and haematological disorders and treatment results of methicillin-resistant staphylococcal septicemia in newborns admitted to[unepsa.org]

Prognosis

  • Abstract Abstract Objective: To analyze the epidemic characters, pathogenesis, clinical manifestations, laboratory data, therapeutic response, and prognosis in patients with staphylococcus septicemia-associated hemophagocytic lymphohistiocytosis(HLH).[bloodjournal.org]
  • Prognosis : often fatal if not treated. Good prognosis if individual cases treated early. Historical note A number of experimental rabbit models have been developed to study staphylococcal infections.[vetstream.com]
  • The prognosis may be worse in older patients and in men.[microbiologybook.org]

Etiology

  • Wallace MR; Mascola JR, Oldfield EC III: Red man syndrome: Incidence, etiology, and prophylaxis. J Infect Dis 1991;164:1180–1195. Bassetti D, Cruciani M: Teicoplanin therapy in children: A review. Scand J Infect Dis Suppl 1990;72:35–37.[karger.com]
  • . - Etiology of bacterial endocarditis before and since the introduction of antibiotics. Ann. Intern. Med. 58: 946, 1963. [ Links ] 46) WISE, R. I. - The staphylococcus approach to therapy. Med. Clin.[scielo.br]
  • Etiology Most cases of sepsis occur as the result of an infection of the urinary tract, lungs, or the peritoneum. Other sources of sepsis include skin, soft tissue, and central nervous system (CNS) infections.[atsu.edu]
  • Bacterial etiology of serious infections in young infants in developing countries: results of a multicenter study. The WHO Young Infants Study Group. Pediatr Infect Dis J 1999 ; 18 (10 suppl): S17 –22.[adc.bmj.com]
  • Needle aspiration for the etiologic diagnosis of children with cellulitis in the era of community-acquired methicillin-resistant Staphylococcus aureus. Clin Pediatr (Phila). 2011 Jun. 50(6):503-7. [Medline].[emedicine.medscape.com]

Epidemiology

  • Epidemiology Many neonates are colonized with S aureus within the first postnatal week. Thereafter, up to 50% of healthy individuals carry at least one strain of S aureus in the anterior nares at any given time.[pedsinreview.aappublications.org]
  • “Molecular Epidemiology of Staphylococcus epidermidis in a Neonatal Intensive Care Unit over a Three-Year Period.” Journal of Clinical Microbiology. Vol. 38, No. 5 (May 2000); p. 1740-1746 6. Picture: Web Page By: Mohammad Bukhari September 27, 2004[web.uconn.edu]
  • Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus. Medscape Today from Emerg Infect Dis 7(2), 2001 [On-line article]. Available online at . Estrada, B. (2004 March 2). MRSA in Patients With Cystic Fibrosis.[labtestsonline.it]
  • Epidemiology of methicillin-resistant Staphylococcus aureus. Clin Infect Dis. 2008 Jun 1. 46 Suppl 5:S344-9. [Medline]. Tenover FC, Goering RV. Methicillin-resistant Staphylococcus aureus strain USA300: origin and epidemiology.[emedicine.medscape.com]
Sex distribution
Age distribution

Pathophysiology

  • For now, identifying sepsis means identifying the signs and symptoms of SIRS.Pathophysiology The complex pathophysiology of sepsis produces a dizzying array of physiologic responses.[americannursetoday.com]
  • This cytokine release mediates the TSS; the resultant pathophysiology mimics that of endotoxic shock.[emedicine.medscape.com]

Prevention

  • Centers for Disease Control and Prevention. Overview of Healthcare-associated MRSA. (Online information). Available online at . Accessed December 2007. Centers for Disease Control and Prevention. Overview of Community-associated MRSA.[labtestsonline.it]
  • Prevention Not all infections can be prevented, but the chances of spreading infections, including MRSA, can be greatly reduced by following these tips: Wash your hands often, particularly if you are in a healthcare facility.[sepsis.org]
  • […] blood poisoning is to treat and prevent infections.[healthline.com]
  • The best way to prevent staph is to keep hands and wounds clean. Most staph skin infections are easily treated with antibiotics or by draining the infection.[icdlist.com]
  • Staph bacteria can spread to others through: close skin contact sharing things like towels or toothbrushes droplets in coughs and sneezes (less common) You can't always prevent staph infections It can be difficult to prevent staph infections because many[nhs.uk]

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