Presentation
We herein present the case of a 43-year-old male diabetic patient who presented with an aggressive form of infective endocarditis involving the tricuspid, mitral and aortic valves following a gluteal abscess due to infection with Staphylococcus lugdunensis [ncbi.nlm.nih.gov]
Clinicians would be able to discontinue antibiotics when SA is not present, to discontinue other broad-spectrum antibiotics when SA is present, or to replace empiric vancomycin with nafcillin when MSSA is identified. [clinicaltrials.gov]
Entire Body System
- Fever
Here we present a case of a left lower lobectomy patient that was complicated by pleural effusion and high fever with positive sputum cultures of Raoultella Ornithinolytica and positive pleural fluid cultures of Staphylococcus hominis. [ncbi.nlm.nih.gov]
Patients may present with nonspecific symptoms such as fever and fatigue. [lecturio.com]
Symptoms typically include a persistent high fever and sometimes shock. Endocarditis can quickly damage heart valves, leading to heart failure (with difficulty breathing) and possibly death. Osteomyelitis causes chills, fever, and bone pain. [merckmanuals.com]
- Sepsis
Staphylococcal sepsis is a leading cause of shock, circulatory collapse, and death in people with severe burns over large areas of the body. When untreated, S. aureus sepsis carries a mortality (death) rate of over 80%. [medicinenet.com]
Let’s talk antibiotics The Staphylococcus aureus bacterium is a common pathogen and can potentially cause sepsis. [healtheuropa.eu]
In case of a weakened immune system, however, is can cause wound infections and even sepsis. Many variants of Staphylococcus aureus are resistant against common antibiotics. [dzif.de]
In healthcare settings, these staph infections can be serious or fatal, including: Bacteremia or sepsis when bacteria spread to the bloodstream. [cdc.gov]
- Swelling
If the staph infection spreads, the person may develop a fever, sometimes with chills and sweats, as well as swelling in the area. [webmd.com]
Cellulitis (sell-yuh-LYE-tus): This begins as a small area of redness, pain, swelling, and warmth on the skin, usually on the legs. As this area spreads, a child may feel feverish and ill. [kidshealth.org]
Symptoms include redness, swelling, and pain at the site of infection. S. aureus can also cause serious infections such as pneumonia (infection of the lungs) or bacteremia (bloodstream infection). [health.state.mn.us]
- Weakness
Moreover, based on SDS-PAGE analysis, isolates with stronger biofilm-forming capabilities induced more inflammatory reactions and had specific banding patterns compared with those of weak biofilm producers. [ncbi.nlm.nih.gov]
Continued MRSA infections are common among people who have weak immune systems who are in hospitals, nursing homes, and other health care centers. [webmd.com]
Weak hemolytic activity (production of δ-hemolysin) on blood agar. Good growth at 10°C, 42°C, and in the presence of 11% NaCl; weak growth in the presence of 12% NaCl or at 5°C. No growth at 0 or 45°C. No growth in M9 minimal agar. [doi.org]
But if these bacteria become resistant to antibiotics, they can cause serious infections, especially in people who are ill or weak. [northshore.org]
- Falling
The term "Bacillus" (capitalized and italicized) is also the name of a genus (Bacillus anthracis) that, among many other genera, falls within the class Bacilli. [en.wikipedia.org]
To determine whether this inhibition occurred against multiple S. aureus strains, we tested a collection of isolates, including strains that fall within the clinically relevant USA300 pulse field type ( Table 1 ), in the bacterial interaction assay. [mbio.asm.org]
Respiratoric
- Pleural Effusion
Here we present a case of a left lower lobectomy patient that was complicated by pleural effusion and high fever with positive sputum cultures of Raoultella Ornithinolytica and positive pleural fluid cultures of Staphylococcus hominis. [ncbi.nlm.nih.gov]
Posteroanterior chest radiograph of a 15-year-old with staphylococcal endocarditis and multiple septic emboli, revealing borderline cardiomegaly, multiple nodular infiltrates, and bilateral pleural effusions. [emedicine.medscape.com]
- Dyspnea
Their symptoms run the gamut from fever, headache, and fatigue to anorexia and dyspnea. Septicemia is especially prevalent resulting from neonatal infections, particularly in very low birth weights. [web.uconn.edu]
Gastrointestinal
- Food Poisoning
Food poisoning from Staphylococcus aureus Staphylococcus aureus has the ability to make seven different toxins that are frequently responsible for food poisoning. [epi.dph.ncdhhs.gov]
At EMS, we test for Staphylococcus aureus, which can cause food poisoning by developing toxins in food and when ingested causes food poisoning. Symptoms develop within 1-6 hours and last anywhere from 30 minutes to 3 days. [expressmicroscience.co.uk]
Around 5 million people in the UK experience food poisoning each year, which includes cases of staphylococcal food poisoning. [thermofisher.com]
Staphylococcus can cause food poisoning when a food handler contaminates food and then the food is not properly refrigerated. Other sources of food contamination include the equipment and surfaces on which food is prepared. [foodsafety.gov]
Lack of hand washing during food preparation can result in S. aureus from hands contaminating food, which may lead to food poisoning. Signs and symptoms Occasionally, S. aureus can cause infection. [sahealth.sa.gov.au]
- Diarrhea
Symptoms include: Severe abdominal cramps Diarrhea Nausea Vomiting Onset time: 1-6 hours Infective Dose: The toxin is produced when the Staphylococcus aureus populations exceed 106 CFU/ gram of food. [food.unl.edu]
Incubation Period 1-6 hours Symptoms Nausea, vomiting, diarrhea, loss of appetite, severe abdominal cramps, mild fever Duration of Illness 24-48 hours What Do I Do? Drink plenty of fluids and get rest. [foodsafety.gov]
Staphylococcal food poisoning is a gastrointestinal illness that causes nausea, vomiting, stomach cramps and diarrhea. It is caused by eating foods contaminated with toxins produced by the bacteria. [epi.dph.ncdhhs.gov]
Do not prepare food if you are ill with diarrhea or vomiting. Wear gloves while preparing food if you have wounds or infections on your hands or wrists. [cdc.gov]
Common clinical features include abdominal pain, diarrhea, vomiting, fever, and dehydration. [lecturio.com]
Cardiovascular
- Hypotension
Widespread exanthem with skin peeling involving palms and soles Myalgias, vomiting, diarrhea Symptoms of shock: hypotension, tachycardia Fever Altered mental status: confusion, lethargy, coma Laboratory tests Treatment IV fluids Remove focus of infection [amboss.com]
If the staph infection is in the blood (called bacteremia or sepsis) symptoms can include fever, chills, and low blood pressure (hypotension). What Types of Diseases Are Caused by Staph? Staphylococcus causes many different types of infections. [onhealth.com]
Symptoms include fever and dangerously low blood pressure (hypotension). Toxic shock syndrome: A severe form of septicemia, toxic shock syndrome (TSS) symptoms include fever, muscle aches and a rash that looks like sunburn. [my.clevelandclinic.org]
Toxic shock syndrome is characterized by the sudden onset of high fever, vomiting, diarrhea, and muscle aches, followed by low blood pressure (hypotension), which can lead to shock and death. [medicinenet.com]
Sepsis The symptoms of sepsis (also known as blood poisoning) usually develop quickly and include: a high temperature (fever) of 38C (100.4F) or above fast heartbeat (tachycardia) fast breathing low blood pressure (hypotension), which will cause you to [hse.ie]
Musculoskeletal
- Arthritis
His finger arthritis was complicated by osteitis 5 weeks later, which resulted in a secondary intervention. This case indicates the virulence of S. argenteus, an emerging pathogen whose clinical effects are poorly described. [ncbi.nlm.nih.gov]
In older adults, an increased frequency of osteoarthritis and rheumatoid arthritis is associated with increasing rates of septic arthritis [25]. [academic.oup.com]
Infections caused by staphylococcal organisms can lead to a variety of diseases, including pneumonia, abscesses, bone infection (osteomyelitis), joint infection (arthritis), and a number of skin infections (eg, impetigo, pimples, boils). [healthychildren.org]
It usually develops suddenly with: A high fever Nausea and vomiting A rash on your palms and soles that looks like a sunburn Confusion Muscle aches Diarrhea Stomach pain Septic arthritis Septic arthritis is often caused by a staph infection. [mayoclinic.org]
- Joint Swelling
Septic arthritis: a condition where a joint becomes infected with Staphylococcus aureus bacteria causing joint swelling, pain and fever. [yourgenome.org]
Signs and symptoms may include: Joint swelling Severe pain in the affected joint Fever When to see a doctor Go to your health care provider if you or your child has: An area of red, irritated or painful skin Pus-filled blisters Fever You may also want [mayoclinic.org]
Skin
- Eczema
Populations at risk for Staphylococcus aureus infection Anyone can develop a staph infection, although certain groups of people are at greater risk, including people with chronic conditions such as diabetes, cancer, vascular disease, eczema, lung disease [cdc.gov]
This includes people with conditions such as: diabetes, cancer, vascular disease, eczema, lung disease, and people who inject drugs. [apic.org]
If your child has eczema, an affected area of skin may become infected with staph. Staph can cause other kinds of illnesses including bone infections, impetigo (school sores), pneumonia and blood stream infections. [rch.org.au]
If a skin condition such as eczema makes regular bathing difficult, ask your doctor for advice. [kidshealth.org]
Medication with systemic steroids, retinoids, cytotoxics or immunosuppressives Immunoglobulin M deficiency Chronic granulomatous disease Chediak-Higashi syndrome Job and Wiskott Aldrich syndromes (associations of severe staphylococcal infection with eczema [dermnetnz.org]
- Dermatitis
These include: Severe atopic dermatitis Poorly controlled diabetes Kidney failure, especially those on dialysis Blood disorders such as leukaemia and lymphoma Malnutrition Iron deficiency Alcoholism Intravenous drug users Presence of foreign body, eg [dermnetnz.org]
[…] but not to HDM allergens was associated with severe atopic dermatitis [30]. [erj.ersjournals.com]
S. aureus may similarly be isolated from abscesses, breast absecesses or mastitis, dermatitis or skin infections and genital tract infections. [news-medical.net]
- Skin Disease
Most staphylococcal infections occur in normal individuals, but underlying illness and certain skin diseases increase the risk of infection. [dermnetnz.org]
แหล่งข้อมูลอื่น Staphylococcus genomes and related information at PATRIC, a Bioinformatics Resource Center funded by NIAID Staphylococcus Infection Pictures - Pictures of Staph Infections, MRSA, and the associated skin diseases caused by these infections [wikiplanet.click]
Skin infections (see above) are the most common type of disease produced by Staphylococcus. [medicinenet.com]
Risk factors: skin disease, venous catheters, other foreign bodies (e.g., prosthetic joints, pacemakers), IDU, hemodialysis, recent surgical procedure. [hopkinsguides.com]
Workup
Workup was consistent with septic arthritis of a native knee, and the patient underwent operative treatment. Cultures from the operating room were speciated to Staphylococcus lugdunensis. [ncbi.nlm.nih.gov]
[…] immediate transesophageal echocardiography (TEE), when possible Transesophageal echocardiography (TEE): For all patients with catheter-related S aureus bacteremia (and no contraindications); for all patients with suspected S aureus endocarditis See Workup [emedicine.medscape.com]
Urine
- Pyuria
Many older patients have significant pyuria but are afebrile and asymptomatic. Bacteremia from a urinary source develops in <5% of patients with S. aureus bacteriuria [27]. [academic.oup.com]
Microbiology
- Staphylococcus Aureus
In this study, polymerase chain reaction-based DNA fingerprinting was used to differentiate coagulase-positive Staphylococcus aureus (CPSA) from coagulase-negative Staphylococcus aureus (CNSA). A total of 29 CNSA and 50 CPSA were evaluated. [doi.org]
Here is the information: ab20002 Anti-Staphylococcus aureus antibody [702] This antibody specifically recognizes peptidoglycan of Staphyloccus aureus, Protein A-negative Staph. aureus and Staph. epidermidis. [abcam.com]
General Information about Staphylococcus aureus Staphylococcus aureus Staphylococcus aureus [staf I lō-kok is aw ree us] (staph), is a type of germ that about 30% of people carry in their noses. [cdc.gov]
Sometimes it is also known as methicillin-sensitive staphylococcus aureus. MRSA Methicillin-resistant Staphylococcus aureus (MRSA) is a type of staph bacteria that is resistant to certain antibiotics called beta-lactams. [dshs.state.tx.us]
- Gram-Positive Coccus
Biochemical identification[edit] Assignment of a strain to the genus Staphylococcus requires it to be a Gram-positive coccus that forms clusters, has an appropriate cell wall structure (including peptidoglycan type and teichoic acid presence) and G + [en.wikipedia.org]
Pathophysiology S aureus is a gram-positive coccus that is both catalase- and coagulase-positive. Colonies are golden and strongly hemolytic on blood agar. [emedicine.medscape.com]
Pleura
- Pleural Effusion
Here we present a case of a left lower lobectomy patient that was complicated by pleural effusion and high fever with positive sputum cultures of Raoultella Ornithinolytica and positive pleural fluid cultures of Staphylococcus hominis. [ncbi.nlm.nih.gov]
Posteroanterior chest radiograph of a 15-year-old with staphylococcal endocarditis and multiple septic emboli, revealing borderline cardiomegaly, multiple nodular infiltrates, and bilateral pleural effusions. [emedicine.medscape.com]
Treatment
Most skin infections will heal within a few weeks, but more serious skin infections can take longer to heal if treatment is delayed or if ineffective treatment is given. [sahealth.sa.gov.au]
Treatment Some skin infections do not require treatment. Others skin infections may require incision and drainage of the infected site and/or antibiotic treatment. [health.state.mn.us]
This case report emphasizes the importance of familiarity with this emerging pathogen in the treatment of a septic joint. [ncbi.nlm.nih.gov]
Prognosis
Staph Infection Prognosis When mild and promptly treated with antibiotics, the prognosis for recovery from a Staph infection is excellent. However, a MRSA infection can have an entirely different outlook. [onhealth.com]
Outlook / Prognosis What is the outlook for someone with a staph infection? Most times, the outlook is favorable for people who have staph infections and are treated properly. [my.clevelandclinic.org]
With the introduction of benzylpenicillin (penicillin G) in the mid-1940s, there was a significant improvement in the prognosis of patients with staphylococcus infections. [scielo.br]
Respiratory tract infection.S. aureus pneumonia has a notoriously poor prognosis, especially for elderly individuals. [academic.oup.com]
Etiology
Abstract The study was performed to assess potential differences in the etiological relevance of two coagulase-negative staphylococci (CoNS), Staphylococcus haemolyticus and Staphylococcus hominis, in an observational single-center study. [ncbi.nlm.nih.gov]
OLIVER 2 1 Department of Food Science, Rutgers University, New Brunswick, New Jersey 08903 2 Institute of Agriculture, The University of Tennessee, Knoxville, Tennessee 37901, USA Staphylococcus aureus is an etiological agent of a wide variety of human [doi.org]
Both infectious and noninfectious etiologies lead to vegetations on the valve leaflets. Patients may present with nonspecific symptoms such as fever and fatigue. [lecturio.com]
Etiology of severe pneumonia in the very elderly, Am J Respir Crit Care Med, 2001, vol. 163 (pg. 645 - 51 ) 36, ,, et al. [academic.oup.com]
Staphylococcal toxic shock syndrome Etiology ∼ 50% of cases: caused by prolonged use of tampons over several days Postsurgical or after wound infections Pathophysiology: exotoxins (see resistance and virulence of staphylococci) Clinical findings: if tampon [amboss.com]
Epidemiology
Benefits of adding genomics to routine epidemiological MRSA surveillance are unknown. Aim To determine feasibility and potential utility of adding genomics to epidemiological surveillance of MRSA. [eurosurveillance.org]
We present a case of a 60-year-old woman with an invasive spinal infection with Staphylococcus pseudintermedius associated with a 15-year-old spinal fixation device and epidemiological contact with dogs. [ncbi.nlm.nih.gov]
Treatment options should be guided by local epidemiological surveillance data and individual antimicrobial susceptibility test results for each patient’s isolates. [ecdc.europa.eu]
Epidemiology Epidemiological data refers to the US, unless otherwise specified. [amboss.com]
“Molecular Epidemiology of Staphylococcus epidermidis in a Neonatal Intensive Care Unit over a Three-Year Period.” Journal of Clinical Microbiology. Vol. 38, No. 5 (May 2000); p. 1740-1746 6. [web.uconn.edu]
Pathophysiology
Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management. Clin. Microbiol. Rev. 2015 Jul;28(3):603-61. [PMC free article: PMC4451395] [PubMed: 26016486] 7. DeLeo FR, Diep BA, Otto M. [ncbi.nlm.nih.gov]
[…] rely on clinical judgment, patient features (e.g. hematologic malignancy / immunosuppression) and number / site (central venous catheter vs. venipuncture) of positive cultures (Eur J Clin Microbiol Infect Dis 2012;31:2639, Clin Infect Dis 2004;39:333) Pathophysiology [pathologyoutlines.com]
Staphylococcal toxic shock syndrome Etiology ∼ 50% of cases: caused by prolonged use of tampons over several days Postsurgical or after wound infections Pathophysiology: exotoxins (see resistance and virulence of staphylococci) Clinical findings: if tampon [amboss.com]
Pathophysiology S aureus is a gram-positive coccus that is both catalase- and coagulase-positive. Colonies are golden and strongly hemolytic on blood agar. [emedicine.medscape.com]
Prevention
interventions primarily target two broad areas: Preventing transmission from colonized persons to uncolonized persons Preventing infection in colonized persons, which includes: Strategies aimed at preventing device-associated and procedure-associated [vdh.virginia.gov]
How to prevent MRSA skin infections To prevent infection from MRSA and other strains of staph, good hygiene (hand washing) practices must be followed. [ohsrep.org.au]
If you cannot drink enough fluids to prevent dehydration, call your doctor. How Can I Prevent Illness? Wash hands and under fingernails vigorously with soap and water before handling and preparing food. [foodsafety.gov]
Prevention: Hand washing is the single most important way to prevent the spread of staph infections. [conditions.health.qld.gov.au]
As a result, pharmaceutical systems and monitoring should be designed to prevent and detect any contamination. [biomerieux-industry.com]