Presentation
We herein present the case of a 43-year-old male diabetic patient who presented with an aggressive form of infective endocarditis involving the tricuspid, mitral and aortic valves following a gluteal abscess due to infection with Staphylococcus lugdunensis [ncbi.nlm.nih.gov]
Clinicians would be able to discontinue antibiotics when SA is not present, to discontinue other broad-spectrum antibiotics when SA is present, or to replace empiric vancomycin with nafcillin when MSSA is identified. [clinicaltrials.gov]
Entire Body System
- Fever
Here we present a case of a left lower lobectomy patient that was complicated by pleural effusion and high fever with positive sputum cultures of Raoultella Ornithinolytica and positive pleural fluid cultures of Staphylococcus hominis. [ncbi.nlm.nih.gov]
Patients may present with nonspecific symptoms such as fever and fatigue. [lecturio.com]
Symptoms typically include a persistent high fever and sometimes shock. Endocarditis can quickly damage heart valves, leading to heart failure (with difficulty breathing) and possibly death. Osteomyelitis causes chills, fever, and bone pain. [merckmanuals.com]
- Weakness
Moreover, based on SDS-PAGE analysis, isolates with stronger biofilm-forming capabilities induced more inflammatory reactions and had specific banding patterns compared with those of weak biofilm producers. [ncbi.nlm.nih.gov]
This type of infection is very common in the general population -- and more common and more severe in people with weak immune systems. People who have diabetes or weakened immunity are particularly prone to developing cellulitis. [webmd.com]
Weak hemolytic activity (production of δ-hemolysin) on blood agar. Good growth at 10°C, 42°C, and in the presence of 11% NaCl; weak growth in the presence of 12% NaCl or at 5°C. No growth at 0 or 45°C. No growth in M9 minimal agar. [doi.org]
But if these bacteria become resistant to antibiotics, they can cause serious infections, especially in people who are ill or weak. [northshore.org]
- Fatigue
Patients may present with nonspecific symptoms such as fever and fatigue. [lecturio.com]
Their symptoms run the gamut from fever, headache, and fatigue to anorexia and dyspnea. Septicemia is especially prevalent resulting from neonatal infections, particularly in very low birth weights. [web.uconn.edu]
Endocarditis causes some flu-like symptoms: fever, chills, and fatigue. It also causes symptoms such as rapid heartbeat, shortness of breath, and fluid buildup in your arms or legs. [medlineplus.gov]
Symptoms include chest pain, coughs, fatigue, shortness of breath, fever and unexplained weight loss. [yourgenome.org]
It creates flu-like symptoms, including fever, fatigue, chills, a fast heartbeat, and shortness of breath. It can also cause fluid to build up in the arms and legs. [medicalnewstoday.com]
- Severe Pain
The first time I went to the doctor he said I might have tendinitis in my hip, 3 days later I was still in severe pain and went to the doctor where he got a blood sample. I was in so much pain I vomited and couldn't drive home. [comments.medicinenet.com]
Signs and symptoms may include: Joint swelling Severe pain in the affected joint Fever When to see a doctor Go to your health care provider if you or your child has: An area of red, irritated or painful skin Pus-filled blisters Fever You may also want [mayoclinic.org]
- Anorexia
Their symptoms run the gamut from fever, headache, and fatigue to anorexia and dyspnea. Septicemia is especially prevalent resulting from neonatal infections, particularly in very low birth weights. [web.uconn.edu]
Signs, symptoms, and laboratory findings The symptoms at presentation were dominated by relatively unspecific symptoms, such as pyrexia (97%), sleep disturbances (93%), anorexia (53%), and back pain (83%) (Table 5). [jamanetwork.com]
Respiratoric
- Sneezing
It is sensible to wash your hands regularly, especially after sneezing and before cooking. Too much soap, though, is not advisable. [micropia.nl]
Contamination occurs from the inhalation of infected droplets caused by coughing or sneezing; consuming foods which have been prepared by an infected individual; and touching surfaces upon which the S. aureus bacteria is present. [thermofisher.com]
These bacteria are spread by having direct contact with an infected person, by using a contaminated object, or by inhaling infected droplets dispersed by sneezing or coughing. [msdmanuals.com]
Good hygiene Avoiding antibiotics The MRSA Vaccine All of the above MRSA most often enters the body through droplets from coughing or sneezing. MRSA is most often spread through direct contact with the bacteria and your skin. [medicinenet.com]
- Sputum
Here we present a case of a left lower lobectomy patient that was complicated by pleural effusion and high fever with positive sputum cultures of Raoultella Ornithinolytica and positive pleural fluid cultures of Staphylococcus hominis. [ncbi.nlm.nih.gov]
Sputum cultures Sputum is the substance that comes up from the respiratory tract during coughing. A sputum culture analyzes the sputum for the presence of bacteria, cell fragments, blood, or pus. [healthline.com]
Before the initiation of empirical therapy, cultures of sputum and blood samples are not frequently performed and chest radiographs are not frequently obtained. [academic.oup.com]
A blood, urine, or sputum sample may also be collected. The sample is sent to a lab to test for staph. If staph is found, it will be tested to see which antibiotic should be used to treat your infection. [medlineplus.gov]
Pneumonia often causes a high fever, shortness of breath, and a cough with sputum that may be tinged with blood. Lung abscesses may develop. [merckmanuals.com]
- Rhinitis
The Western obsession with cleanliness may be partly responsible for the increase in allergic asthma and conditions such as rhinitis. Careful prescribing of antibiotics will minimise the emergence of antibiotic resistant strains of bacteria. [betterhealth.vic.gov.au]
"Staphylococci and staphylococcal superantigens in asthma and rhinitis: a systematic review and meta-analysis". Allergy. 66 (4): 549–555. doi:10.1111/j.1398-9995.2010.02502.x. ISSN 1398-9995. [en.wikipedia.org]
- Nasal Congestion
Local symptoms include inflammation in the nostrils, yellow or green mucus, nasal discharge, nasal congestion, sore throat, fever, cough, and pain in the nasal membranes. [just-health.net]
Gastrointestinal
- Food Poisoning
Food poisoning from Staphylococcus aureus Staphylococcus aureus has the ability to make seven different toxins that are frequently responsible for food poisoning. [epi.dph.ncdhhs.gov]
Around 5 million people in the UK experience food poisoning each year, which includes cases of staphylococcal food poisoning. [thermofisher.com]
At EMS, we test for Staphylococcus aureus, which can cause food poisoning by developing toxins in food and when ingested causes food poisoning. Symptoms develop within 1-6 hours and last anywhere from 30 minutes to 3 days. [expressmicroscience.co.uk]
Staphylococcus can cause food poisoning when a food handler contaminates food and then the food is not properly refrigerated. Other sources of food contamination include the equipment and surfaces on which food is prepared. [foodsafety.gov]
Lack of hand washing during food preparation can result in S. aureus from hands contaminating food, which may lead to food poisoning. Signs and symptoms Occasionally, S. aureus can cause infection. [sahealth.sa.gov.au]
Musculoskeletal
- Arthritis
His finger arthritis was complicated by osteitis 5 weeks later, which resulted in a secondary intervention. This case indicates the virulence of S. argenteus, an emerging pathogen whose clinical effects are poorly described. [ncbi.nlm.nih.gov]
In older adults, an increased frequency of osteoarthritis and rheumatoid arthritis is associated with increasing rates of septic arthritis [25]. [academic.oup.com]
Infections caused by staphylococcal organisms can lead to a variety of diseases, including pneumonia, abscesses, bone infection (osteomyelitis), joint infection (arthritis), and a number of skin infections (eg, impetigo, pimples, boils). [healthychildren.org]
It usually develops suddenly with: A high fever Nausea and vomiting A rash on your palms and soles that looks like a sunburn Confusion Muscle aches Diarrhea Stomach pain Septic arthritis Septic arthritis is often caused by a staph infection. [mayoclinic.org]
Skin
- Eczema
Populations at risk for Staphylococcus aureus infection Anyone can develop a staph infection, although certain groups of people are at greater risk, including people with chronic conditions such as diabetes, cancer, vascular disease, eczema, lung disease [cdc.gov]
If your child has eczema, an affected area of skin may become infected with staph. Staph can cause other kinds of illnesses including bone infections, impetigo (school sores), pneumonia and blood stream infections. [rch.org.au]
If a skin condition such as eczema makes regular bathing difficult, ask your doctor for advice. [kidshealth.org]
This includes people with conditions such as: diabetes, cancer, vascular disease, eczema, lung disease, and people who inject drugs. [apic.org]
Medication with systemic steroids, retinoids, cytotoxics or immunosuppressives Immunoglobulin M deficiency Chronic granulomatous disease Chediak-Higashi syndrome Job and Wiskott Aldrich syndromes (associations of severe staphylococcal infection with eczema [dermnetnz.org]
- Skin Lesion
They can cause various forms of infection such as superficial skin lesions and localized abscesses, deep-seated infections, surgical wound infections, food poisoning, toxic shock syndrome, urinary tract infections, and other forms of infections. [creative-diagnostics.com]
But it is also a major human pathogen, causing diseases ranging from skin lesions (boils, impetigo, etc.) to endocarditis, acute pneumonia, osteomyelitis or sepsis. [sciencedaily.com]
It is able to infect all tissues and organs: skin, subcutaneous tissue, lungs, central nervous system, bones, and joints, etc. This bacterium can cause sepsis, purulent skin lesions, and wound infections. [mlst.net]
During the exam, your doctor looks for skin lesions and other signs of infection. He or she may also use other methods to determine whether you have an infection. [nyulangone.org]
Prevention Exclusion from childcare, preschool, school and work is not necessary unless infected skin lesions on exposed surfaces cannot be completely covered with a dressing. [sahealth.sa.gov.au]
- Dermatitis
These include: Severe atopic dermatitis Poorly controlled diabetes Kidney failure, especially those on dialysis Blood disorders such as leukaemia and lymphoma Malnutrition Iron deficiency Alcoholism Intravenous drug users Presence of foreign body, eg [dermnetnz.org]
[…] but not to HDM allergens was associated with severe atopic dermatitis [30]. [erj.ersjournals.com]
S. aureus may similarly be isolated from abscesses, breast absecesses or mastitis, dermatitis or skin infections and genital tract infections. [news-medical.net]
- Furunculosis
Community-onset methicillin-resistant Staphylococcus aureus associated with antibiotic use and the cytotoxin Panton-Valentine leukocidin during a furunculosis outbreak in rural Alaska. J Infect Dis. 2004 May 1. 189(9):1565-73. [QxMD MEDLINE Link]. [emedicine.medscape.com]
It has potent activity against S. aureus and clinically used in treatment of mild to moderately severe skin and soft-tissue infections, for example, impetigo, folicullitis, erythrasma, furunculosis, abscesses and infected traumatic wounds [113]. [intechopen.com]
- Acne Vulgaris
Preliminary research also indicates S. epidermidis is universally found inside affected acne vulgaris pores, where Cutibacterium acnes is normally the sole resident.[13] Identification[edit] The normal practice of detecting S. epidermidis is by using [en.wikipedia.org]
Staphylococcus epidermidis in the human skin microbiome mediates fermentation to inhibit the growth of Propionibacterium acnes : implications of probiotics in acne vulgaris. Appl. Microbiol. [frontiersin.org]
Neurologic
- Headache
Their symptoms run the gamut from fever, headache, and fatigue to anorexia and dyspnea. Septicemia is especially prevalent resulting from neonatal infections, particularly in very low birth weights. [web.uconn.edu]
Other signs of infection are headache, fever and lack of energy. [ohsrep.org.au]
As the infection worsens, symptoms might also include fever, chills, and sinus headaches. Staph can also trigger distant symptoms. These symptoms affect the skin and include pimples, impetigo, boils, abscesses, carbuncles, and cellulitis. [just-health.net]
It’s important to see your doctor right away if you notice any of the following symptoms: rash headaches muscle aches chills fever fatigue cough shortness of breath chest pain Symptoms of CA-MRSA CA-MRSA usually causes skin infections. [healthline.com]
Symptoms include: a high temperature (fever) of 38C (100.4F) or above chills sweating, including night sweats muscular aches and pains chest pain coughs weakness and fatigue headache shortness of breath unexplained weight loss Page last reviewed: 13/07 [hse.ie]
Urogenital
- Kidney Failure
You may have a higher risk of developing a staph infection if you have an underlying medical condition, such as: Diabetes Human immunodeficiency virus or acquired immunodeficiency syndrome Cancer Kidney failure A skin condition, such as eczema An open [everydayhealth.com]
People who may be more likely to get a staph infection include those with: Diabetes who use insulin HIV/AIDS Kidney failure requiring dialysis Weakened immune systems — either from a disease or medications that suppress the immune system A transplant [mayoclinic.org]
- Renal Insufficiency
In a cohort of patients with mild or moderate renal insufficiency, more than 80% responded to treatment, with no detrimental effect on their kidneys. [emedicine.medscape.com]
Workup
Workup was consistent with septic arthritis of a native knee, and the patient underwent operative treatment. Cultures from the operating room were speciated to Staphylococcus lugdunensis. [ncbi.nlm.nih.gov]
[…] immediate transesophageal echocardiography (TEE), when possible Transesophageal echocardiography (TEE): For all patients with catheter-related S aureus bacteremia (and no contraindications); for all patients with suspected S aureus endocarditis See Workup [emedicine.medscape.com]
Microbiology
- Gram-Positive Bacteria
From Wikidata Jump to navigation Jump to search genus of Gram-positive bacteria edit Language Label Description Also known as English Staphylococcus genus of Gram-positive bacteria Statements Micrografia fet amb SEM de colònies de S. aureus. [wikidata.org]
Histopathologic examination confirmed the diagnosis of lung abscess, and colonies of gram-positive bacteria were identified. [ncbi.nlm.nih.gov]
Figure 4: A general model for peptide-mediated quorum sensing in Gram-positive bacteria. In Gram-positive bacteria, a peptide signal precursor locus is translated into a precursor protein (black and ... [doi.org]
- Gram-Positive Coccus
Biochemical identification[edit] Assignment of a strain to the genus Staphylococcus requires it to be a Gram-positive coccus that forms clusters, has an appropriate cell wall structure (including peptidoglycan type and teichoic acid presence) and G + [en.wikipedia.org]
Pathophysiology S aureus is a gram-positive coccus that is both catalase- and coagulase-positive. Colonies are golden and strongly hemolytic on blood agar. [emedicine.medscape.com]
Treatment
Most skin infections will heal within a few weeks, but more serious skin infections can take longer to heal if treatment is delayed or if ineffective treatment is given. [sahealth.sa.gov.au]
Treatment Some skin infections do not require treatment. Others skin infections may require incision and drainage of the infected site and/or antibiotic treatment. [health.state.mn.us]
This case report emphasizes the importance of familiarity with this emerging pathogen in the treatment of a septic joint. [ncbi.nlm.nih.gov]
The ten treatments are shown in Table 1. Table 1. Treatments for indoor study in controlled environment. [extension.psu.edu]
Prognosis
Staph Infection Prognosis When mild and promptly treated with antibiotics, the prognosis for recovery from a Staph infection is excellent. However, a MRSA infection can have an entirely different outlook. [onhealth.com]
Outlook / Prognosis What is the outlook for someone with a staph infection? Most times, the outlook is favorable for people who have staph infections and are treated properly. [my.clevelandclinic.org]
With the introduction of benzylpenicillin (penicillin G) in the mid-1940s, there was a significant improvement in the prognosis of patients with staphylococcus infections. [scielo.br]
Respiratory tract infection.S. aureus pneumonia has a notoriously poor prognosis, especially for elderly individuals. [academic.oup.com]
Etiology
Abstract The study was performed to assess potential differences in the etiological relevance of two coagulase-negative staphylococci (CoNS), Staphylococcus haemolyticus and Staphylococcus hominis, in an observational single-center study. [ncbi.nlm.nih.gov]
OLIVER 2 1 Department of Food Science, Rutgers University, New Brunswick, New Jersey 08903 2 Institute of Agriculture, The University of Tennessee, Knoxville, Tennessee 37901, USA Staphylococcus aureus is an etiological agent of a wide variety of human [doi.org]
Both infectious and noninfectious etiologies lead to vegetations on the valve leaflets. Patients may present with nonspecific symptoms such as fever and fatigue. [lecturio.com]
Etiology of severe pneumonia in the very elderly, Am J Respir Crit Care Med, 2001, vol. 163 (pg. 645 - 51 ) 36, ,, et al. [academic.oup.com]
Staphylococcal toxic shock syndrome Etiology ∼ 50% of cases: caused by prolonged use of tampons over several days Postsurgical or after wound infections Pathophysiology: exotoxins (see resistance and virulence of staphylococci) Clinical findings: if tampon [amboss.com]
Epidemiology
Benefits of adding genomics to routine epidemiological MRSA surveillance are unknown. Aim To determine feasibility and potential utility of adding genomics to epidemiological surveillance of MRSA. [eurosurveillance.org]
We present a case of a 60-year-old woman with an invasive spinal infection with Staphylococcus pseudintermedius associated with a 15-year-old spinal fixation device and epidemiological contact with dogs. [ncbi.nlm.nih.gov]
Treatment options should be guided by local epidemiological surveillance data and individual antimicrobial susceptibility test results for each patient’s isolates. [ecdc.europa.eu]
Epidemiology Epidemiological data refers to the US, unless otherwise specified. [amboss.com]
“Molecular Epidemiology of Staphylococcus epidermidis in a Neonatal Intensive Care Unit over a Three-Year Period.” Journal of Clinical Microbiology. Vol. 38, No. 5 (May 2000); p. 1740-1746 6. [web.uconn.edu]
Pathophysiology
Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management. Clin. Microbiol. Rev. 2015 Jul;28(3):603-61. [PMC free article: PMC4451395] [PubMed: 26016486] 7. DeLeo FR, Diep BA, Otto M. [ncbi.nlm.nih.gov]
[…] rely on clinical judgment, patient features (e.g. hematologic malignancy / immunosuppression) and number / site (central venous catheter vs. venipuncture) of positive cultures (Eur J Clin Microbiol Infect Dis 2012;31:2639, Clin Infect Dis 2004;39:333) Pathophysiology [pathologyoutlines.com]
Staphylococcal toxic shock syndrome Etiology ∼ 50% of cases: caused by prolonged use of tampons over several days Postsurgical or after wound infections Pathophysiology: exotoxins (see resistance and virulence of staphylococci) Clinical findings: if tampon [amboss.com]
Pathophysiology S aureus is a gram-positive coccus that is both catalase- and coagulase-positive. Colonies are golden and strongly hemolytic on blood agar. [emedicine.medscape.com]
Prevention
How to prevent MRSA skin infections To prevent infection from MRSA and other strains of staph, good hygiene (hand washing) practices must be followed. [ohsrep.org.au]
interventions primarily target two broad areas: Preventing transmission from colonized persons to uncolonized persons Preventing infection in colonized persons, which includes: Strategies aimed at preventing device-associated and procedure-associated [vdh.virginia.gov]
If you cannot drink enough fluids to prevent dehydration, call your doctor. How Can I Prevent Illness? Wash hands and under fingernails vigorously with soap and water before handling and preparing food. [foodsafety.gov]
As a result, pharmaceutical systems and monitoring should be designed to prevent and detect any contamination. [biomerieux-industry.com]
Prevention: Hand washing is the single most important way to prevent the spread of staph infections. [conditions.health.qld.gov.au]