Presentation
Typification of strains through PFGE and spa-typing revealed that some carriers present the same strain, whereas others present different strains along the period of persistence. Almost all strains induced a strong biofilm formation. [ncbi.nlm.nih.gov]
Interestingly, some clones belonging to different CCs presented a higher PFGE similarity than clones included in the same CC. [doi.org]
Entire Body System
- Sepsis
Staphylococcal sepsis is a leading cause of shock, circulatory collapse, and death in people with severe burns over large areas of the body. When untreated, S. aureus sepsis carries a mortality (death) rate of over 80%. [medicinenet.com]
These metabolic changes in the urine preceded the clinical severe sepsis phenotype, suggesting that detection of the extent of metabolic disruption can aid in the early identification of a sepsis phenotype in advance of the clinical diagnosis. [ncbi.nlm.nih.gov]
- Pain
The clinical features include fever, spinal pain, radiating nerve root pain and leg weakness. When sepsis is present, prompt recognition is required to initiate appropriate antimicrobial therapy and surgical decompression. [ncbi.nlm.nih.gov]
Most MRSA infections are skin infections that may appear as pustules or boils which often are red, swollen, painful, or have pus or other drainage. [tn.gov]
S. aureus is the leading cause of skin and soft tissue infections, such as abscesses, boils, furuncles, and cellulitis (red, swollen, painful, warm skin). [apic.org]
- Inflammation
In mice, both EGF and pimecrolimus groups showed less erythema with significantly reduced inflammation and decreased expression of thymic stromal lymphopoietin. EGF relieved S. aureus -induced inflammation and AD-like skin lesions in Nc/Nga mice. [ncbi.nlm.nih.gov]
- Swelling
Here, we report the case of a 64-year old woman presenting with chills, pain and swelling of her right foot with dark maculae at the sole, and elevated inflammatory markers. [ncbi.nlm.nih.gov]
Your Care Instructions Stomatitis is swelling and redness of the lining of your mouth. It can cause painful sores that can make it hard for you to eat, drink, or swallow. [myhealth.alberta.ca]
Symptoms include redness, swelling, and pain at the site of infection. S. aureus can also cause serious infections such as pneumonia (infection of the lungs) or bacteremia (bloodstream infection). [health.state.mn.us]
It can involve open sores (canker sores) or redness and swelling. It occurs on the inside of the cheeks or on the tongue or gums. Stomatitis is more common in children, but it can occur at any age. [fairview.org]
- Wound Infection
BACKGROUND: Wound infections after adult spinal deformity surgery place a high toll on patients, providers, and the healthcare system. [ncbi.nlm.nih.gov]
One way of getting MRSA is to make direct contact with a wound infected with MRSA. Also, if someone with a wound infected with MRSA wipes the wound with a towel or other item, the bacteria will spread to that item. [my.clevelandclinic.org]
In case of a weakened immune system, however, is can cause wound infections and even sepsis. Many variants of Staphylococcus aureus are resistant against common antibiotics. [dzif.de]
Respiratoric
- Pneumonia
We compared eight retrospective and eight prospective cases of PVL-positive S aureus pneumonia with 36 cases of PVL-negative S aureus pneumonia. [ncbi.nlm.nih.gov]
- Cough
Wear a surgical mask if you have respiratory symptoms like cough, sneeze, runny nose and sore throat. Young children with symptoms of infections should minimise contact with other children. 4. [chp.gov.hk]
In this study, we describe a previously healthy 3-months-old infant who was admitted with high fever, cough, and respiratory distress, who had a history of varicella infection three weeks before, with exposure from her adolescent, unvaccinated sister. [ncbi.nlm.nih.gov]
Pneumonia often causes a high fever, shortness of breath, and a cough with sputum that may be tinged with blood. Lung abscesses may develop. [msdmanuals.com]
- Sneezing
Wear a surgical mask if you have respiratory symptoms like cough, sneeze, runny nose and sore throat. Young children with symptoms of infections should minimise contact with other children. 4. [chp.gov.hk]
It is sensible to wash your hands regularly, especially after sneezing and before cooking. Too much soap, though, is not advisable. [micropia.nl]
These bacteria are spread by having direct contact with an infected person, by using a contaminated object, or by inhaling infected droplets dispersed by sneezing or coughing. [msdmanuals.com]
When an infected person coughs or sneezes, he or she releases numerous small droplets of saliva that remain suspended in air. These contain the bacteria and can infect others. [news-medical.net]
Gastrointestinal
- Food Poisoning
If you think you may have food poisoning, contact your physician. How should a patient with suspected staphylococcal food poisoning be treated? For most patients, staphylococcal food poisoning will cause a brief illness. [stopfoodborneillness.org]
What is staphylococcal food poisoning? Staphylococcal food poisoning is a gastrointestinal illness. It is caused by eating foods contaminated with toxins produced by Staphylococcus aureus. [web.archive.org]
Food poisoning from Staphylococcus aureus Staphylococcus aureus has the ability to make seven different toxins that are frequently responsible for food poisoning. [epi.dph.ncdhhs.gov]
Learn about this topic in these articles: Assorted References antibiotic treatment In antibiotic: Penicillins …decreased activity, however, against penicillinase-producing Staphylococcus aureus, a common bacterial agent in food poisoning. [britannica.com]
- Diarrhea
Food poisoning typically causes nausea and vomiting, diarrhea, and a fever. If you lose too many fluids, you may also become dehydrated. Pneumonia symptoms include a high fever, chills, and cough that doesn't get better. [nlm.nih.gov]
Symptoms include: Severe abdominal cramps Diarrhea Nausea Vomiting Onset time: 1-6 hours Infective Dose: The toxin is produced when the Staphylococcus aureus populations exceed 106 CFU/ gram of food. [food.unl.edu]
[…] of syndromes with a range of clinical manifestations; clinically different in general community, newborns, menstruating women, and hospitalized patients; food intoxication is characterized by abrupt/violent onset, severe nausea, cramps, vomiting, and diarrhea [msdsonline.com]
Staphylococcal food poisoning is a gastrointestinal illness that causes nausea, vomiting, stomach cramps and diarrhea. It is caused by eating foods contaminated with toxins produced by the bacteria. [epi.dph.ncdhhs.gov]
- Vomiting
Toxin-producing Staphylococcus aureus can be identified in stool or vomit using specialized techniques. The toxins can be detected in food items. [web.archive.org]
Toxin-producing Staphylococcus aureus can be identified in stool or vomit, and toxin can be detected in food items. Diagnosis of staphylococcal food poisoning in an individual is generally based only on the signs and symptoms of the patient. [stopfoodborneillness.org]
Food poisoning typically causes nausea and vomiting, diarrhea, and a fever. If you lose too many fluids, you may also become dehydrated. Pneumonia symptoms include a high fever, chills, and cough that doesn't get better. [nlm.nih.gov]
Staph food poisoning is characterized by a sudden start of nausea, vomiting, and stomach cramps. Most people also have diarrhea. [cdc.gov]
- Nausea
Breathing in low doses of staphylococcal enterotoxin B may cause fever, cough, difficulty breathing, headache, and some vomiting and nausea. High doses of the toxin have a much more serious effect. Top of Page [web.archive.org]
Symptoms include: Severe abdominal cramps Diarrhea Nausea Vomiting Onset time: 1-6 hours Infective Dose: The toxin is produced when the Staphylococcus aureus populations exceed 106 CFU/ gram of food. [food.unl.edu]
Staphylococcal food poisoning is a gastrointestinal illness that causes nausea, vomiting, stomach cramps and diarrhea. It is caused by eating foods contaminated with toxins produced by the bacteria. [epi.dph.ncdhhs.gov]
The most common symptoms of the disease are nausea, vomiting, aversion to food, abdominal cramps, and diarrhea. The rehabilitation period takes, as a rule, 1-3 days. In severe cases, a full recovery may take longer. [mlst.net]
Symptoms of SFP include: diarrhea vomiting nausea abdominal cramping Illness is generally mild, and most people recover within one to three days. SFP is caused by contaminated food products. [healthline.com]
- Abdominal Pain
A 55-year-old man with history of chronic hepatitis B cirrhosis presented to an emergency department in California with abdominal pain, constipation, and jaundice. [ncbi.nlm.nih.gov]
Primary response was defined as resolution of abdominal pain, clearing of dialysate, and PDE neutrophil count <100/ml on day 10 with antibiotics alone. [cjasn.asnjournals.org]
It usually develops suddenly with: A high fever Nausea and vomiting A rash on your palms and soles that resembles sunburn Confusion Muscle aches Diarrhea Abdominal pain Septic arthritis Septic arthritis is often caused by a staph infection. [mayoclinic.org]
Side effects of nafcillin are naturally mild and include: nausea vomiting abdominal pain If the infection is caused by meticillin-resistant staphylococcus aureus (MRSA), an antibiotic called vancomycin is prescribed. [hse.ie]
Disease occurs 2-6 hours after ingestion with nausea, vomiting, abdominal pain, and diarrhea. It is typically self-limited with resolution of symptoms within 6-12 hours. [infectiousdiseaseadvisor.com]
Skin
- Erythema
Although hypotension was not observed, we diagnosed probable toxic shock syndrome (TSS) based on fever (temperature: >38.9 °C), altered mental status, erythema, desquamation, thrombocytopenia, liver dysfunction, and creatine phosphokinase elevation. [ncbi.nlm.nih.gov]
Erythema and edema are the usual oral manifestations, often with ulcerations. Some will have constitutional symptoms: low-grade fever, malaise, lymphadenopathy, and headache. Pain will vary. [unboundmedicine.com]
All were afebrile and showed no signs of illness other than generalized erythema, with no lysis of the epidermis. The rash resembled streptococcal scarlet fever, including non-blanching accentuation of the erythema in the flexion creases. [cirp.org]
Figures and Tables - Analysis 1.5 Comparison 1 Oral Antibiotics vs placebo, Outcome 5 Number of people with erythema at end of treatment. [doi.org]
Workup
Describe the workup of a patient with staphylococcus infection. Summarize the treatment options for staphylococcus infections. [ncbi.nlm.nih.gov]
Minimizing the workup of blood culture contaminants: implementation and evaluation of a laboratory-based algorithm. J Clin Microbiol. 2002;40:2437-2444. [go to PubMed] 2. Weinstein MP, Towns ML, Quartey SM, et al. [psnet.ahrq.gov]
[…] progress rapidly Pleural effusion, pneumatoceles, and pneumothorax are also common In oncology patients, S aureus may cause pulmonary nodules [7] Thrombophlebitis Obtain a blood culture through the intravenous line and a peripheral blood culture See Workup [emedicine.medscape.com]
Microbiology
- Staphylococcus Aureus
Staphylococcus aureus eowiki Staphylococcus aureus eswiki Staphylococcus aureus etwiki Staphylococcus aureus euwiki Staphylococcus aureus fawiki استافیلوکوکوس اورئوس fiwiki Staphylococcus aureus frwiki Staphylocoque doré glwiki Staphylococcus aureus [wikidata.org]
Risk of methicillin-resistant Staphylococcus aureus infection after previous infection or colonization. Clin Infect Dis. 2003;36:281-5. Safdar N, Bradley E. The risk of infection after nasal colonization with Staphylococcus aureus. [revistas.urosario.edu.co]
INSDC Staphylococcus aureus subsp. aureus DSM 20231 14.SASA.1_5, whole genome shotgun sequence AMYL01000005 WGS 17411 1241616 * [Ref.: #20218] Whole Genome Shotgun (WGS) Sequence INSDC Staphylococcus aureus subsp. aureus DSM 20231 14.SASA.1_6, whole [bacdive.dsmz.de]
- Gram-Positive Bacteria
Many surface proteins are anchored to the cell wall of Gram-positive bacteria and are involved in the pathogenesis of these organisms. [ncbi.nlm.nih.gov]
See all Hide authors and affiliations Science 07 Apr 1995: Vol. 268, Issue 5207, pp. 103-106 DOI: 10.1126/science.7701329 Abstract Many surface proteins are anchored to the cell wall of Gram-positive bacteria and are involved in the pathogenesis of these [doi.org]
Peptidoglycan from S. aureus PGN-SA is peptidoglycan (PGN) purified from the Gram-positive bacterium, Staphylococcus aureus. PGN is a major surface component of Gram-positive bacteria. [invivogen.com]
ABSTRACT The transfer of gram-positive bacteria, particularly multiresistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE), among patients is a growing concern. [jcm.asm.org]
- Candida
We describe a novel strategy by which S. aureus is able to invade host tissue and disseminate via adherence to the invasive hyphal elements of Candida albicans. [ncbi.nlm.nih.gov]
Infections may require specific treatment such as antibiotics for streptococcal pharyngitis, topical antifungal or oral antifungal agent for candida infection. [dermnetnz.org]
Treatment
Contact laser treatment caused a focal temperature increase up to 58°C, whereas plasma treatment led a uniform temperature distribution on the disc within safe limits. [ncbi.nlm.nih.gov]
Prognosis
Long-term prognosis for adult cases of NP currently remains undocumented. [ncbi.nlm.nih.gov]
Prognosis[edit] The prognosis of SSSS in children is excellent, with complete resolution within 10 days of treatment, and without significant scarring. [en.wikipedia.org]
Etiology
Over the last decades Staphylococcus aureus (SA) has become the dominant etiology of native valve infective endocarditis, with the community-acquired methicillin-sensible Staphylococcus aureus (CA-MSSA) strains being the prevailing type. [ncbi.nlm.nih.gov]
Epidemiology
Conclusion The data suggest that some strains can adapt and colonize new epidemiologically unrelated habitats. [ncbi.nlm.nih.gov]
Thus, it is very useful and important molecular tool in understanding the potential epidemiological background of the strains. 3.1.4. [intechopen.com]
International surveillance Joana Rolo, Ons Bouchami, Nuno Faria, Maria Miragaia In Europe the epidemiology of nosocomial MRSA is well understood, but the epidemiology of CA-MRSA is incompletely documented due to poor geographic coverage and outdated data [itqb.unl.pt]
Pathophysiology
All efforts by S. aureus to resist neutrophil-mediated killing stress the importance of these mechanisms in the pathophysiology of staphylococcal diseases. [annualreviews.org]
Objectives: Review the pathophysiology of S aureus infections. Describe the workup of a patient with staphylococcus infection. Summarize the treatment options for staphylococcus infections. [ncbi.nlm.nih.gov]
Prevention
Thus we must elucidate the mechanisms behind S aureus nasal carriage and infection to be able to develop new preventive strategies. [ncbi.nlm.nih.gov]
“To date, there is no licensed vaccine available to prevent invasive S. aureus disease. [pfizer.com]
This finding underscores the importance of extending efforts to prevent and reduce the spread of methicillin-resistant S. aureus beyond inpatient facilities. [doi.org]
Use contact precautions (e.g., procedures to prevent droplet or aerosols). Post signs at the entrance to patient area. Single patient rooms may be used with designated toilets and sinks. [ccohs.ca]