We present three cases of statin-induced musculoskeletal symptoms which presented to an orthopaedic department. [ncbi.nlm.nih.gov]

Sexual health for the man at midlife: in-office workup. Geriatrics 1997 ; 52 : 76 –86. 16 Shetty HGM, Routledge PA. Adverse effects of hypolipidaemic drugs. Adverse Drug Reaction Bull 1990 ; 142 : 532 –535. 17 Monk JP, Todd PA. Bezafibrate. [fampra.oxfordjournals.org]

These data, coupled with the patient findings, indicate a possible association between statin treatment, decreased ubiquinone status, and loss of complex IV activity. [ncbi.nlm.nih.gov]

In this trial, early treatment with atorvastatin 80 mg/d reduced recurrent ischemic events over a 16-week treatment period among patients with unstable angina or non–Q-wave acute MI. [jama.ama-assn.org]

Statins have been demonstrated to significantly affect the prognosis and outcome of patients with risk factors to atherosclerosis (in primary and secondary prevention trials). [ncbi.nlm.nih.gov]

The clinical prognosis of FH heterozygotes is related not only to the magnitude of the elevation in plasma LDL-C but also to the presence of other coronary risk factors ( 5 ). New insights into pathogenesis. [doi.org]

Its insidence remains high and the management has not been established yet because its etiology and pathophysiological are still poorly understood. [ncbi.nlm.nih.gov]

The etiologic role of statins in the risk of MM, however, is not well understood. [bloodjournal.org]

Rider, Trouble in Paradise: Unmeasured Confounding in Registry-based Studies of Etiologic Factors, European Urology, 69, 5, (883), (2016). [doi.org]

Ockene), Department of Medicine, University of Massachusetts Medical School, Worcester; Division of Biostatistics and Epidemiology, University of Massachusetts Amherst, Amherst (Dr Balasubramanian); Department of Social and Preventive Medicine, University [web.archive.org]

The results need to be verified with observed CVD epidemiology. [hauptverband.at]

Stroup DF, Berlin JA, Morton SC, Olkin I, Williamson GD, Rennie D, Moher D, Becker BJ, Sipe TA, Thacker SB (2000) Meta-analysis of observational studies in epidemiology: a proposal for reporting. meta-analysis of observational studies in epidemiology [doi.org]

This article reviews the epidemiology, clinical features, risk factors and mechanisms of statin-induced myopathy and provides an evidence-based algorithm for managing patients with statin myopathy. [ncbi.nlm.nih.gov]

Its insidence remains high and the management has not been established yet because its etiology and pathophysiological are still poorly understood. [ncbi.nlm.nih.gov]

Areas covered : In this review, we summarize the role of Rho-associated coiled-coil containing kinase (ROCK) and its potential as a therapeutic target in stroke pathophysiology. [doi.org]

Rhabdomyolysis and Other Causes of Myoglobinuria In this article Pathophysiology Statins and myotoxicity Rhabdomyolysis can be defined as a clinical syndrome associated with the breakdown of skeletal muscle fibres and myocyte cell membranes, leading to [patient.co.uk]

[…] in preventing all-cause mortality. [ncbi.nlm.nih.gov]

Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS: Air Force/Texas Coronary Atherosclerosis Prevention Study. JAMA 1998;279(20):1615–1622. [doi.org]