Presentation
We review the literature and present an additional case to emphasize the subtle changes that resulted in positive outcome when diagnosed and managed in a comprehensive transplant team. [ncbi.nlm.nih.gov]
Entire Body System
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Pseudotumor
We describe the first reported pediatric patient to our knowledge with a spindle cell pseudotumor caused by Mycobacterium genavense in a hematopoietic stem cell transplant recipient, and review the literature of such an entity in the transplant population [ncbi.nlm.nih.gov]
Neurologic
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Cognitive Impairment
Four themes were identified relating to patients' feeling 'dead', disconnecting and isolating themselves, cognitive impairment and engagement with exercise and its benefits in recovery. [ncbi.nlm.nih.gov]
Impairment CTFPHC Addictions Anxiety Bipolar Depression Obsessive Compulsive Disorder Pediatrics Psychosis Psychosomatic Acute Kidney Injury Chronic Kidney Disease Fluids & Electrolytes Glomerulonephritis Hemodialysis Hypertension REFERENCE BOOK Screening [qxmd.com]
Common symptoms of MS include numbness or tingling of the face and body, walking and balance difficulties, involuntary muscle spasms, pain, weakness, fatigue, dizziness and cognitive impairment. [medicalnewstoday.com]
Workup
In addition, transplant coordinators are responsible for initiating the workup of donors and performing infusions once patients are admitted. [uhhospitals.org]
It is also reasonable to screen for asymptomatic portal hypertension in the pretransplantation workup, since numerous factors in myelofibrosis may impair liver function. There is also the issue of managing relapses after stem cell transplant. [ascopost.com]
Biopsy
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Liver Biopsy
Liver biopsy showed histology suggestive of autoimmune-like hepatitis, which is a rare manifestation of chronic "hepatitic" graft versus host disease. The Author(s) 2015. [ncbi.nlm.nih.gov]
biopsy should be reserved for patients in whom the diagnosis is unclear For prophylaxis, defibrotide is recommended at a dosage of 6.25 mg/kg IV every 6 hours in children and adults undergoing allogeneic HSCT who have certain risk factors Defibrotide [emedicine.medscape.com]
Treatment
A thematic content analysis was performed, and three themes were assessed: what is oral health, why was pre-transplant dental treatment performed, and what was the relevance of dental treatment for the haematopoietic stem cell transplant. [ncbi.nlm.nih.gov]
Prognosis
Prognosis is poor, particularly after allogeneic transplantation, and literature to guide clinical decision-making is scarce. [ncbi.nlm.nih.gov]
Etiology
Its etiology is related to endothelial injury accompanied by complement activation. [ncbi.nlm.nih.gov]
Epidemiology
RSV-B genomes from 16 patients and health care workers (HCWs) suspected to be involved in the outbreak were compared to RSV-B genomes that were acquired from outpatients during the same time period but epidemiologically unrelated to the outbreak. [ncbi.nlm.nih.gov]
"Future epidemiologic studies and disease prevention studies will need to include this growing patient population. [healio.com]
An exceptional outcome Keener was so thankful and invigorated by her recovery that she soon returned to Dana-Farber/Boston Children’s as a part-time researcher in Epidemiology. [blog.dana-farber.org]
Our study is reported according to the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines (the checklist used is included in the eAppendix in the Supplement ). [jamanetwork.com]
Pathophysiology
This observation might have important drawbacks as far as HSCT-TMA pathophysiology and treatment are concerned. [ncbi.nlm.nih.gov]
[…] require therapy.4 The cells express pan B-cell markers and are usually positive for CD5, CD20, CD10 and CD23 and are negative for CD3 and CD103.5 The 6q deletion is present in 42% of patients and is associated with an adverse prognosis.6 Waldenström pathophysiology [nature.com]
Prevention
Antibiotics, antifungal medications, and antiviral medications can help prevent and treat bacterial, fungal, and viral infections. [webmd.com]
The reason for performing prior dental treatment involves strict guidelines for transplants, and when questioned as to the importance of the dental treatment for transplants, the interviewed subjects' statements focused on the prevention of infections [ncbi.nlm.nih.gov]
Some are meant to prevent nausea from chemotherapy, some to prevent infections, others to prevent complications from the chemotherapy drugs. Many are given by mouth, some are given by vein. [franciscanhealth.org]
Your healthcare provider may prescribe medication to prevent fungal infections. Scientists are still learning about which transplant patients are at highest risk and how to best prevent fungal infections. 7,8 Protect yourself from the environment. [cdc.gov]