The microorganism is a very rare cause of endocarditis and its presentation with multiple liver abscesses is highly unusual. [ncbi.nlm.nih.gov]

• Inflammation

  In severe cases, group A hemolytic streptococcus can cause a variety of diseases such as pharyngitis (strep throat), tonsillitis, impetigo*1 in addition to the usual skin rash, cellulitis,*2 middle ear inflammation, pneumonia, septic arthritis, osteomyelitis [otsuka.co.jp]

  Author information 1 Department of Microbiology and Molecular Genetics, The Institute for Medical Research, Israel-Canada (IMRIC), The Hebrew University of Jerusalem, Faculty of Medicine, Jerusalem 9112102, Israel. 2 NUS-HUJ-CREATE Programme for Inflammation [ncbi.nlm.nih.gov]

  Streptococcal toxic shock syndrome, acute rheumatic fever (joint inflammation, carditis and CNS complications), post-streptococcal glomerulonephritis (inflammation, hematuriia, fever, edema, hypertension, urinary sediment abnormalties and severe kidney [msdsonline.com]

  More invasive infections pose a more serious threat to health and include: pneumonia (inflammation of the tissue in the lungs) meningitis (inflammation of the membranes covering the brain and spinal cord) bacteraemia (infection of the blood). [yourgenome.org]

• Asymptomatic

  Included studies reporting the prevalence of asymptomatic GAS carriage needed to state participants were asymptomatic. RESULTS: 285 eligible studies were identified. [ncbi.nlm.nih.gov]

  A throat swab should be taken when a pregnant woman presents with a sore throat and there should be a lower threshold for antibiotic treatment. 4 Invasive GAS outbreaks have been linked to asymptomatic health care workers. [health.nsw.gov.au]

• Collapse

  Colonies initially appear with a plateau-type morphology, then start to collapse in the centers when autolysis begins. [textbookofbacteriology.net]

  The GAS virulence in S. pyogenes-PF may involve the ability to produce circulatory collapse-inducing factors rather than the tissue invasiveness of strain. [ann-clinmicrob.biomedcentral.com]

  Collapse strain/species ID relevant genotypic features genetic marker source R6 non-encapsulated derivative of D39 laboratory isolate LytA Δ- LytA in the R6 background A. [rspb.royalsocietypublishing.org]

• Aspiration

  The patient was successfully treated by stereotactic aspiration and antibiotherapy. [ncbi.nlm.nih.gov]

  From this site it can aspire to the lungs, eventually spread to the blood and traverse the blood-brain barrier to the meninges, once inside the blood it can cause infections throughout the body. [web.uconn.edu]

  As well as bacterial pneumonia, other types include: viral pneumonia – most commonly caused by the respiratory syncytial virus (RSV) and sometimes influenza type A or B; viruses are a common cause of pneumonia in young children aspiration pneumonia – [nhs.uk]

  […] erythromycin, other macrolides, and cephalosporins have been shown to be effective treatments.[25] Treatment with ampicillin/sulbactam, amoxicillin/clavulanic acid, or clindamycin is appropriate if deep oropharyngeal abscesses are present, in conjunction with aspiration [en.wikipedia.org]

• Skin Disease

  Group A hemolytic streptococcus is also known as a causative bacterium of streptococcal toxic shock syndrome, which causes tissue necrosis (death of tissue) and shock. 1Impetigo: a general term for skin diseases whose predominant symptoms are pustules [otsuka.co.jp]

  When Group A streptococci literally get under the skin, they can foster a common skin disease known as impetigo. This contagious disease frequently afflicts mainly children during the summer, when insect bites, cuts and scrapes are prevalent. [healthcentral.com]

  Most human diseases are due to group A organisms but a few can be caused by members of group B, C and G also. THE DISEASE: A pus-generating infection of the skin or mucous membranes. [atsu.edu]

• Petechiae

  Strep throat Symptoms may include a swollen red sore throat and tonsil (pharyngeal and tonsillar erythema), tonsillar hypertrophy with or without exudates, palatal petechiae (uncommon but highly specific finding), high fever, headache, and swollen lymph [nccid.ca]

  Scarlet fever: pharyngitis symptoms (see above), pastia (pink or red lines formed of confluent petechiae, which are small purple or red spots in the skin caused by minor blood vessel breaks) that are found in skin creases, especially the flexor surface [medicinenet.com]

  Petechiae spread over the face, body and upper extremities. [ann-clinmicrob.biomedcentral.com]

• Purpura

  Next day, leg purpura and acral gangrene extended. [ann-clinmicrob.biomedcentral.com]

  These include anaphylactoid purpura, Kawasaki disease, pediatric autoimmune neuropsychiatric disorder associated with streptococcal infection, acute demyelinating encephalomyelitis, cutaneous polyarteritis nodosa and others. [journals.lww.com]

• Pruritus

  Symptoms include a serous vaginal discharge, erythema of the vulvar area, and intense pruritus. Therapy consists of orally administered penicillin for 10 days. Patients allergic to penicillin can be treated with erythromycin. [antimicrobe.org]

• Flushing

  Scarlet fever is caused by group A streptococcal strains that produce an erythrogenic toxin, leading to a diffuse pink-red cutaneous flush that blanches with pressure. [msdmanuals.com]

• Vaginal Discharge

  discharge after delivery) vaginal bleeding. [health.nsw.gov.au]

  Call your healthcare provider right away if you experience any of the following: Your water breaks You have more vaginal discharge than usual or your vaginal discharge changes Vaginal bleeding Increased pressure in your pelvis or vagina Cramping in your [groupbstrepinternational.org]

  Symptoms include a serous vaginal discharge, erythema of the vulvar area, and intense pruritus. Therapy consists of orally administered penicillin for 10 days. Patients allergic to penicillin can be treated with erythromycin. [antimicrobe.org]

• Kidney Failure

  Serious Complications Include Long-term Kidney Damage Most people who develop PSGN recover within a few weeks without any complications. While rare, long-term kidney damage, including kidney failure, can occur. [cdc.gov]

  Most people with PSGN recover within a few weeks, but in rare instances long-term kidney damage, including kidney failure, can occur. (5) Group B Streptococcus Group B streptococcus, also known as group B strep or GBS, is a type of bacteria that can cause [everydayhealth.com]

  SpeA is a characteristic unique to emm1 types and associated with severe infections such as kidney failure [96, 97]. SP7’s profile matched that of M3 MGAS315, indicating the implication of these two strain’s in throat infections. [journals.plos.org]

• Renal Function Impairment

  Adults with PSGN are more likely to have a worse outcome due to residual renal function impairment.1 Prevention Unfortunately, antibiotics do not prevent PSGN from developing in persons with acute streptococcal infections (impetigo or pharyngitis).1,2 [cdc.gov]

• Seizure

  A 44-year-old male presented with headache and occasional episodes of vomiting for 2 weeks, weakness of the left upper and lower limbs for 1 week, and 1 episode of generalized tonic clonic seizure 2 days back. [ncbi.nlm.nih.gov]

  If it progresses, confusion, headaches, seizures, and skin loss from the palms of the hands and from the soles of the feet can occur. [medicinenet.com]

  Symptoms are related to the body systems that are affected by the infection and may include breathing problems, changes in blood pressure, or neurologic problems such as seizures. [stanfordchildrens.org]

No other focus of infection was identified on imaging workup suggesting primary infection of the pericardium. His clinical course was complicated by development of constrictive pericarditis for which he underwent surgical pericardiectomy. [ncbi.nlm.nih.gov]

Because there are many other groups of Streptococcus spp., positive identification of the infecting bacteria is necessary to separate out other bacteria that may cause some similar symptoms but may require a different workup, different treatment, and [medicinenet.com]

• Neutrophilia

  Laboratory investigations revealed leucocytosis with neutrophilia. CT of the neck showed right internal jugular vein thrombosis with an overlying abscess and a nodular opacity in the right lung apex with air locules. [ncbi.nlm.nih.gov]

The most frequently antimicrobials used for treatment were ceftriaxone + levofloxacin. Ten patients cured with a combination of medical and surgical treatment and 2 patients died as a consequence of infection. [ncbi.nlm.nih.gov]

In this paper, we discuss why contemporary probiotics are inadequate for treatment of oral malodour and examine the rationale for selection of particular bacterial species for future use in the treatment of this condition. [doi.org]

Early treatment of deep infections (for example, excision, drainage, and antibiotic treatment of rectal abscesses) helps prevent invasive GAS disease. [medicinenet.com]

In this aging society, invasive infections with SDSE should be much more recognized among medical practitioners in order to improve patient prognosis. [ncbi.nlm.nih.gov]

What is the prognosis for group A streptococcal infections? The prognosis for mild GAS infections is usually good to excellent. [medicinenet.com]

This small series supports recognition of group G Streptococcus in the etiology of STSS. We propose intravenous immunoglobulin be used in treatment as it is for STSS caused by group A Streptococcus. [ncbi.nlm.nih.gov]

[…] associated with streptococcal infections PSGN : poststreptococcal glomerulonephritis STSS : streptococcal toxic shock syndrome Education Gaps Clinical prediction rules for group A Streptococcus pharyngitis are unreliable in children, and unless viral etiology [pedsinreview.aappublications.org]

ETIOLOGICAL AGENT: Streptococcus pyogenes NOTE: All beta-hemolytic streptococci are grouped from A to U based on the C-antigen (Lancefield classification). [atsu.edu]

Here, we illustrate their epidemiological risk factors, clinical presentation and resulting sequelae of both patients. [ncbi.nlm.nih.gov]

Epidemiology of Streptococcus pyogenes. Streptococcus pyogenes: basic biology to clinical manifestations [Internet], [12] A. Filleron, E. Jeziorski, A.L. Michon, M. Rodière, H. Marchandin. [analesdepediatria.org]

[…] the culture of specimens from epidemiologically linked healthcare workers (HCWs) (7). [isid.org]

The group a streptococcus are beta haemolytic cocci able to produce some exotoxins and also contain many surface antigens that play a vital role in its pathophysiology such as m proteins. [youtube.com]

Pathophysiology and predisposing factors The pathophysiology of STSS is based on bacterial toxins. [annalsofintensivecare.springeropen.com]

It may corroborate a pivotal role of the circulatory failure in the pathophysiology of S. pyogenes-PF. [ann-clinmicrob.biomedcentral.com]

Recent interest in the pathophysiology of this disorder has focused on the role of streptococcal pyrogenic exotoxins (SPEs), extracellular products of group A streptococci that mediate not only scarlatiniform-like rashes but also multi-organ damage and [antimicrobe.org]

However, there is still controversy about its prevention. [web.archive.org]

Centers for Disease Control and Prevention. Prevention of Perinatal Group B Streptococcal Disease Revised Guidelines from CDC, 2010. Disponible en : http://www.cdc.gov/groupbstrep/guidelines 35. [revistas.unab.edu.co]

[…] in pregnant mothers in Fiji to prevent serious bacterial infections in their babies. [mcri.edu.au]

Strategies for prevention of invasive GAS disease, although limited, include infection-control measures and prevention of secondary cases among postpartum and postsurgical patients [ 11 ]. [doi.org]

GBS Prevention Working Group, London, England; James H. [cdc.gov]