Presentation
After 2010, there was a decrease in serotypes 14, 1, 23F and 5 and an increase in serotypes 3, 12F, 11A and 8, which were not present in the vaccine. CONCLUSIONS: The present study noted the increase in serotypes 3, 12F, 11A and 8 after vaccination. [ncbi.nlm.nih.gov]
Entire Body System
- Asymptomatic
We validated this method on non-pneumococcal isolates cultured from cases of severe streptococcal disease ( n = 101) and from carriage ( n = 103), and on non-typeable pneumococci from asymptomatic individuals ( n = 17) and on whole-genome sequences of [ncbi.nlm.nih.gov]
NESp strains compose approximately 3% to 19% of asymptomatic carriage isolates and harbor multiple antibiotic resistance genes. [mbio.asm.org]
- Fatigue
A 62-year-old splenectomized woman was admitted because of upper respiratory tract symptoms, general fatigue, and purpura. [ncbi.nlm.nih.gov]
She also endorses shortness of breath and severe fatigue. Her vital signs are as follows: T 38.5 C, HR 98, BP 110/66, RR 18, SpO2 94% on room air. [medbullets.com]
After incubation the infected individual will begin to acquire symptoms such as a high fever, chills, cough, sore throat, chest pains, body aches, fatigue, rapid breathing, and maybe even nausea/vomiting. (10 and 11). [austincc.edu]
Recent estimates suggest 27% of community-acquired pneumonia cases are S. pneumoniae (Said, 2013) Often develops as a secondary pneumonia during upper respiratory tract infections Abrupt onset of fever, shaking chills, cough, dyspnea, tachypnea, and fatigue [arupconsult.com]
- Splenectomy
In addition, we suggest a thorough medical interview and checkup for splenectomy or hyposplenism in prenatal women. [ncbi.nlm.nih.gov]
When elective splenectomy, immunocompromising therapy, or cochlear implant placement is being planned, PCV13 and/or PPSV23 vaccination should be completed at least 2 weeks before surgery or initiation of therapy. [cdc.gov]
- Shivering
Symptoms include: Confusion or disorientation Shortness of breath High heart rate Fever, shivering, or feeling very cold Extreme pain or discomfort Clammy or sweaty skin Pneumococcus bacteria cause up to half of middle ear infections (otitis media). [cdc.gov]
Sepsis (complication caused by the body’s overwhelming and life-threatening response to an infection) symptoms: confusion or disorientation, shortness of breath, high heart rate, fever, shivering, or feeling very cold, extreme pain or discomfort, clammy [dshs.texas.gov]
[…] be dry, or produce thick yellow, green, brown or blood-stained mucus (phlegm) difficulty breathing – your breathing may be rapid and shallow, and you may feel breathless, even when resting rapid heartbeat fever feeling generally unwell sweating and shivering [nhs.uk]
- Anemia
Multiple myeloma most commonly affects patients who are >60 years of age, and causes clinical symptoms from anemia, lytic bone lesions, hypercalcemia, and renal failure. [ncbi.nlm.nih.gov]
Controlling the abnormalities caused by the renal failure, anemia, and thrombocytopenia is essential. [link.springer.com]
Gastrointestinal
- Nausea
Pneumococcal meningitis People with pneumococcal meningitis often have: high fever headache stiff neck nausea and vomiting photophobia (discomfort when looking at light). [sahealth.sa.gov.au]
After incubation the infected individual will begin to acquire symptoms such as a high fever, chills, cough, sore throat, chest pains, body aches, fatigue, rapid breathing, and maybe even nausea/vomiting. (10 and 11). [austincc.edu]
Her symptoms are associated with neck stiffness and nausea. Physical examination is significant for nuchal rigidity and an inability to extend at the knee while the hips are flexed at 90 °. [medbullets.com]
You may first have a severe shaking chill which is usually followed by: High fever Cough Shortness of breath Rapid breathing Chest pains Other symptoms may include: Nausea Vomiting Headache Tiredness Muscle aches Diagnosis Your healthcare provider can [medicinenet.com]
- Abdominal Pain
pain, coryza, myalgia, Vomiting, diarrhoea, fever, abdominal pain Vomiting, diarrhoea, fever, abdominal pain Diarrhoea, fever, abdominal pain, myalgia, headache Medical and surgical history SLEa, pericarditis, pleuritis, depression, LLETZb procedure [ncbi.nlm.nih.gov]
Haug Browse recently published Learning/CME Learning/CME View all learning/CME CME Partial Oral versus Intravenous Antibiotic Treatment of Endocarditis Case 4-2019: An 18-Year-Old Man with Abdominal Pain and Hematochezia Bridging the Gap Challenge Yourself [nejm.org]
Women or girls who have primary peritonitis due to ascent of pneumococci via the genital tract present with lower abdominal pain and fever and have abdominal tenderness on examination. [journals.lww.com]
- Intestinal Disease
[…] concomitant metabolic abnormalities. Thus, a 24-hour urinary collection (for calcium, oxalate, uric acid, citrate, phosphate, uric acid, magnesium, sodium, total volume, and pH) can be done. 17. Recurrent stone formers Strong family history of stones Intestinal [slideshare.net]
- Constipation
Aluminium hydroxide can cause constipation, anorexia, lethargy, bone pain & hypercalciuria. These regimens are usually not recommended due to these side effects Avoidance of foods and vitamins supplements high in phosphorus & magnesium is recommended [slideshare.net]
Cardiovascular
- Heart Disease
CONTINUE SCROLLING OR CLICK HERE FOR RELATED SLIDESHOW SLIDESHOW Heart Disease: Causes of a Heart Attack See Slideshow [medicinenet.com]
Susceptible populations include infants and young children, the elderly, those with serious chronic health problems such as heart disease and diabetes; those with compromised immunity; and certain ethnic groups such as Alaskan Natives and Native Americans [dph.georgia.gov]
People who have conditions that weaken the immune system, like diabetes, heart disease, lung disease, and HIV/AIDS, or people who smoke cigarettes or have asthma are also at increased risk for getting pneumococcal disease. [wwwnc.cdc.gov]
Neurologic
- Confusion
Symptoms include: Fever and chills Cough Rapid breathing or difficulty breathing Chest pain Older adults with pneumococcal pneumonia may experience confusion or low alertness, rather than the more common symptoms listed above. [cdc.gov]
Pneumococcal meningitis symptoms: include stiff neck, fever, mental confusion and disorientation, and visual sensitivity to light. [dshs.texas.gov]
If the infection spreads to the brain and spinal cord, it can cause pneumococcal meningitis, characterised by a stiff neck, fever, confusion, and headaches. Pneumococcal infection is responsible for 1-2 million infant deaths worldwide, every year. [creative-diagnostics.com]
- Headache
If the infection spreads to the brain and spinal cord, it can cause pneumococcal meningitis, characterised by a stiff neck, fever, confusion, and headaches. Pneumococcal infection is responsible for 1-2 million infant deaths worldwide, every year. [creative-diagnostics.com]
Diagnosis Indications for Testing Fever or chills, cough, shortness of breath, tachypnea, tachycardia, infiltrates on chest x-ray, suggesting pneumonia Fever, neck pain and stiffness, headache, suggesting meningitis Fever or chills, hypotension, tachycardia [arupconsult.com]
Snapshot A 56-year-old man presents to the emergency department for a severe headache, generalized malaise, and fatigue. Her symptoms are associated with neck stiffness and nausea. [medbullets.com]
Workup
We acknowledge that our diagnosis is presumptive since cultures from sterile sites (ie, blood) were negative; an extensive workup for other etiologies was negative. [journals.lww.com]
Significant in her medical history was a parathyroidectomy 7 years ago for hyperparathyroidism, discovered following metabolic workup for nephrolithiasis; serum parathyroid hormone and calcium levels returned to normal. [liebertpub.com]
[…] prevention. 17, 18 A metabolic workup including blood and urine laboratory tests are indicated. [journals.sagepub.com]
Blood culture was not a part of the standard diagnostic workup in our study. However, no more than 20% of pediatric patients with pneumococcal CAP usually have positive blood culture results [35–37]. [academic.oup.com]
Nonetheless, concern has been raised more recently about an increase that has since been observed in the severity of asthma symptoms and the need for more intensive care management. [3] (See Prognosis, Workup, Treatment, and Medication .) [emedicine.medscape.com]
Treatment
AOM, and post-treatment visits), based on their phenotypic and genotypic characteristics performed by analyses of serotype, antibiotic susceptibility patterns and multilocus sequence typing. [ncbi.nlm.nih.gov]
Other diagnostic tools include urinary antigen rapid tests for teichoic acid (polysaccharide of the cell wall of the bacteria).4 Treatment Treatment will usually include a broad-spectrum cephalosporin, and often vancomycin, until results of antibiotic [quidel.com]
Treatment The treatment will depend on how the bacteria affect the individual. Noninvasive pneumococcal infections Often, a person will recover from a mild pneumococcal infection without any treatment. [medicalnewstoday.com]
Prognosis
However, complete staghorn calculus is rare in polycystic kidney disease and predicts a gloomy prognosis of kidney. [semanticscholar.org]
Treatment and prognosis Staghorn calculi need to be treated surgically, usually PCNL (percutaneous nephrolithotomy) +/- ESWL (extracorporeal shockwave lithotripsy) and the entire stone removed, including small fragments, as otherwise, these residual fragments [radiopaedia.org]
Etiology
Laboratory evaluation.Table 3 shows the laboratory data by etiologic group. [academic.oup.com]
Applicable To Bronchopneumonia due to S. pneumoniae Code First Code First Help Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10data.com]
BACKGROUND: Streptococcus pneumoniae is the main etiology of community-acquired pneumonia (CAP). A quick detection of urinary antigen helps in obtaining a documented result in case of Streptococcus pneumoniae CAP. [ncbi.nlm.nih.gov]
Epidemiology
In addition to the selection pressure resulting from misuse of antibiotics, widespread vaccination programmes may contribute to changing pneumococcal epidemiology. [ncbi.nlm.nih.gov]
Isolation Clinical specimen - human, Portugal, 1996 References representative strain of the Pneumococcal Molecular Epidemiology Network (PMEN) Sa-Leao R, et al. [atcc.org]
Pathophysiology
Useful For Suggests clinical disorders or settings where the test may be helpful Rapid diagnosis of pneumococcal pneumonia Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test Streptococcus [mayocliniclabs.com]
Pathophysiology The precise pathophysiology of pneumococcal HUS has not been determined. However, there is evidence of a role for the Thomsen–Friedenreich (TF) cryptantigen [ 39 ]. [link.springer.com]
"Intravascular hemolysis and the pathophysiology of sickle cell disease". Journal of Clinical Investigation. 127 (3): 750–760. doi:10.1172/JCI89741. ISSN 0021-9738. [en.wikipedia.org]
Prevention
Control and Prevention, State Key Laboratory for Infectious Disease Prevention and Control, Chinese Center for Disease Control and Prevention, Beijing 102206, China; Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, [ncbi.nlm.nih.gov]
Centers for Disease Control and Prevention. 2015. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Streptococcus pneumoniae, 2015. Centers for Disease Control and Prevention. [cdc.gov]
Prevnar 13® is the trade name in the United States, Canada, and Taiwan. 1 Centers for Disease Control and Prevention. Pneumonia can be prevented - vaccines can help. http://www.cdc.gov/features/pneumonia/. [pfizer.com]
[…] of Vaccine-Preventable Diseases Ask the Experts about PCV13 and PPSV23 CDC experts answer your clinical questions (Immunization Action Coalition) Use of Vaccines to Prevent Meningitis in Persons with Cochlear Implants Updated Apr 2012 Facts about pneumococcal [web.archive.org]