Presentation
A case of stress polycythemia without symptoms of cerebral ischemia is presented. [ncbi.nlm.nih.gov]
Butterworth-Heinemann, ٢٢/١٠/٢٠١٣ - 1300 من الصفحات Stress in Health and Disease presents the principal pathways mediating the response to a stressor. It discusses the clinical background of cross-resistance and treatment with stress-hormones. [books.google.com]
One half of the patients studied in the present series, and 47% of those previously reported had severe cardiovascular disease; 71% of the latter patients also had arterial hypertension. [jamanetwork.com]
Splenomegaly absent absent present in 75% of the cases 9. Hepatomegaly absent absent present in 35% of the cases 10. Heart or lung disease absent present absent 11. Cyanosis may be present present absent Possible References Used Back to tests [labpedia.net]
He is presenting with significant symptoms of hyperviscosity and should be considered to be at significant risk of thrombotic complications. [brainscape.com]
Entire Body System
- Fatigue
We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition. Last updated: January 31, 2019 [patientslikeme.com]
Fatigue and headache were common, and syncopal attacks occurred in four patients. [nejm.org]
On this subject I am 24 and having severe concentration problems fatigue and memory issues so bad currently right now that I cant even enjoy life to its fullest extent dating friends etc. [curezone.org]
See also altitude sickness, erythrocytosis. observations Clinical manifestations for polycythemia include weakness and fatigue; headache and vertigo; visual disturbances (scotoma, double or blurred vision); dyspnea; nosebleeds; night sweats; and epigastric [medical-dictionary.thefreedictionary.com]
[…] bleeding due to a cut or a nosebleed Intense and frequent bone pain and/or muscle pain Headaches, lightheadedness or gastrointestinal symptoms Vision problems Ringing in the ears Difficulty or labored breathing The color of the skin appears reddish Fatigue [cancer.uvahealth.com]
- Thyroid Nodule
Dyskinesia 464 Taste and Smell Loss 465 Testicular Failure 466 Testicular Neoplasm 467 Testicular Pain 468 Tetanus 469 Thromboangiitis Obliterans 470 Thrombocytopenia Inherited Disorders 471 Thrombocytopenia in Pregnancy 472 Thrombophlebitis Superficial 473 Thyroid [books.google.de]
Cardiovascular
- Hypertension
Patients with arterial pressure elevation should be treated vigorously with close observation for control of hypertension and remission of the polycythemia. (JAMA 229:159-162, 1974) [jamanetwork.com]
Some of these patients are on diuretic therapy for hypertension, which further contracts plasma volume. Again, hematological diagnosis by estimation of blood volume is needed for certainty and rational management. [alpfmedical.info]
A careful physical examination discovered that the child had severe hypertension. Extensive laboratory investigations did not reveal a cause for his hypertension. [ncbi.nlm.nih.gov]
The early history of hypertension is not a story of progressive achievement. [books.google.de]
Eyes
- Strabismus
Compression Epidural 444 Spinal Epidural Abscess 445 Spinal Tumors 446 Splenomegaly 447 Splenomegaly and Hepatomegaly 448 Spontaneous Miscarriage 450 Squamous Cell Carcinoma 451 Status Epilepticus 452 Stomatitis Bullous 453 Stomatitis Red Lesions 454 Strabismus [books.google.de]
Musculoskeletal
- Knee Pain
Anterior Hip Medial Thigh Knee 288 Joint Pain Hip Lateral Thigh 289 Joint Pain Polyarticular 290 Jugular Venous Distention 291 Kawasakis Disease 292 Kidney Enlargement Unilateral 293 Knee Pain in Different Age Groups 294 Korsakoffs Psychosis 295 Lactose [books.google.de]
Skin
- Flushing
Clinical features include facial flushing, pruritus, erythromelalgia, headaches, and dizziness. Severe complications such as thrombotic events (e.g., stroke, Budd-Chiari syndrome) may occur. [amboss.com]
Now my symptoms as you know were Severe Fatigue, Severe Facial Flushing, Very fast heart rate, confusion and drowsiness, Memory Problems, Short term memory loss. ------------------------------------------------------- Verifiable sources: (I will put quotes [curezone.org]
Weakness, fatigue, headache, blood clotting, vertigo, tinnitus, irritability, dyspnea, visual disturbances, flushing of face, redness, or ruddy cyanosis, pruritus, ecchymosis, hypertension, epigastric distress, weight loss, and pain in joints or extremities [medical-dictionary.thefreedictionary.com]
Effects upon fishes of a periodic flushing of electrical power plants boiler tubes with chlorine. M.A. Thesis, Southern Illinois Univ. at carbondale. 37 pp. Google Scholar Davidsohn, I. & D. A. Nelson. 1969. The blood. pp. 120–330. In: I. [link.springer.com]
On examination, he had obvious truncal obesity and a flushed complexion. Blood pressure was 128/82 mmHg, heart rate 78/min, respiratory rate 16/min and oxygen saturations 99% on air. [brainscape.com]
Psychiatrical
- Chronic Anxiety
Behavioral/emotional stress and chronic anxiety have been shown to cause changes in hemorheologic measures, possibly due to increases in catecholamines and blood pressure [18]. [journals.plos.org]
Urogenital
- Vaginal Bleeding
Bleeding Pregnancy 492 Varicocele 493 Vasculitis Diseases That Mimic Vasculitis 494 Venous Lake 495 Ventricular Septal Defect 496 Vesiculobullous Diseases 497 Vesiculopustules Newborn Infants 498 Vision Loss Chronic Progressive 499 Vocal Cord Paralysis [books.google.de]
- Pelvic Pain
Disease 375 Paroxysmal Cold Hemoglobinuria PCH 377 Pedophilia 378 Pelvic Pain Chronic 379 Pemphigus Vulgaris 380 Peptic Ulcer Disease 381 Pericarditis 382 Peritoneal Carcinomatosis 383 Peritonitis Secondary 384 Periumbilical Swelling 385 Photodermatoses [books.google.de]
- Dysuria
Versicolor Pityriasis Versicolor 477 Toxic Epidermal Necrolysis 478 Toxoplasmosis 479 Tracheitis 480 Trichotillomania 481 Tropical Sprue 482 Tubulointerstitial Kidney Disease 483 Tumor Markers Elevation 484 Turners Syndrome 485 Urethral Discharge and Dysuria [books.google.de]
Neurologic
- Headache
One visible symptom of polycythemia vera are headaches, according to this research from the National Institutes of Health. By reducing blood flow to the brain, painful headaches can become quite common. [activebeat.com]
Clinical features include facial flushing, pruritus, erythromelalgia, headaches, and dizziness. Severe complications such as thrombotic events (e.g., stroke, Budd-Chiari syndrome) may occur. [amboss.com]
This may cause sluggishness, irritability, headache, dizziness, fainting, disturbances of sensation in the hands and feet, and a feeling of fullness in the head. There may be episodes of acute pain as spontaneous clots occur in the blood vessels. [medical-dictionary.thefreedictionary.com]
Fatigue and headache were common, and syncopal attacks occurred in four patients. [nejm.org]
Symptoms may include: Abnormal and heavy bleeding due to a cut or a nosebleed Intense and frequent bone pain and/or muscle pain Headaches, lightheadedness or gastrointestinal symptoms Vision problems Ringing in the ears Difficulty or labored breathing [cancer.uvahealth.com]
- Dizziness
Clinical features include facial flushing, pruritus, erythromelalgia, headaches, and dizziness. Severe complications such as thrombotic events (e.g., stroke, Budd-Chiari syndrome) may occur. [amboss.com]
When left untreated, these headaches can intensify, leading to dizziness, lightheadedness, and overall feelings of weakness. If these feelings become a part of your daily routine, be sure to talk to your doctor. ADVERTISEMENT [activebeat.com]
These include: headaches blurred vision red skin – particularly in the face, hands and feet tiredness high blood pressure dizziness discomfort in the tummy confusion bleeding problems – such as nosebleeds and bruising gout – which can cause joint pain [nhs.uk]
Polycythemia Vera clinical features: Face appears suffused with blood, retinal veins are engorged, frequent headaches, dizziness, blurred vision and tinnitus. [quizlet.com]
Persons with polycythemia vera have an exceptionally ruddy complexion, with red discoloration of the face and sometimes the extremities, and may have headache, dizziness, difficulty in breathing, a feeling of fullness, skin changes (e.g., tendency to [britannica.com]
- Lethargy
These included “feeding problems” (21.8%), plethora (20.0%), lethargy (14.5%), cyanosis (14.5%), respiratory distress (9.1%), jitteriness (7.3%), and hypotonia (7.3%). Other findings included hypoglycemia (40.0%) and hyperbilirubinemia (21.8%). [medtextfree.wordpress.com]
- Trichotillomania
Disorders 471 Thrombocytopenia in Pregnancy 472 Thrombophlebitis Superficial 473 Thyroid Nodule 474 TickRelated Infections 475 Tinea Corporis 476 Tinea Versicolor Pityriasis Versicolor 477 Toxic Epidermal Necrolysis 478 Toxoplasmosis 479 Tracheitis 480 Trichotillomania [books.google.de]
- Nystagmus
Pain 343 Necrobiosis Lipoidica 344 Nephroblastoma 345 Neuroblastoma 346 Neuroleptic Malignant Syndrome 347 Neurologic Deficit Multifocal 348 Neuropathies with Facial Nerve Involvement 349 Neutropenia 350 Nevus of Ota and Ito 351 Nodules Painful 352 Nystagmus [books.google.de]
Workup
The initial workup of erythrocytosis is dependant on the probability of polycythemia vera as the underlying cause. A serum erythropoietin level is usually the first step. [thebigl.co]
See Presentation and Workup. To the extent that the increased RBCs alleviate tissue hypoxia, secondary polycythemia may in fact be beneficial. [emedicine.medscape.com]
Axis
- Right Axis Deviation
Axis Deviation 427 Rosacea 428 Salivary Gland Enlargement 429 Sarcoidosis 430 Schistosomiasis 431 Scrotal Pain 432 Seasonal Affective Disorder 433 Seizures Absence 434 Septicemia 435 Serotonin Syndrome 436 Sexually Transmitted Diseases Anorectal Region [books.google.de]
Ultrasound
- Ovarian Mass
Mass 364 Pagets Disease of Bone 365 Pain Midfoot 366 Pain Posterior Heel 367 Palpitations 368 Pancreatitis Acute 369 Panic Disorder 370 Papilledema 371 Paraneoplastic Neurologic Syndromes 372 Paranoid Personality Disorder 373 Paraplegia 374 Parkinsons [books.google.de]
Other Test Results
- Decreased Plasma Volume
Since the Hct is a ratio between the number of circulating RBCs per unit volume of whole blood, an elevated Hct may be caused by a decreased plasma volume. Thus, true erythrocytosis is based on demonstrating an increased RBC mass. [163.178.103.176]
Nervous stress leads to hemoconcentration by some unknown mechanism, possibly by temporarily decreasing circulating plasma volume or by vascular redistribution of erythrocytes. high normal RBC mass and low normal plasma volume. [doctor-clinic.org]
Relative/pseudo polycythaemia occurs due to decreased plasma volume. This may occur due to dehydration (eg vomiting, diarrhoea, diuretics) A special form of relative polycythaemia is Gaisbocks. [mrcpandme.blogspot.com]
There is pseudopolycythemia where red cell volume is normal but the plasma volume is reduced. [labpedia.net]
Treatment
After 6 months of treatment, the TOS, OSI and MDA levels were significantly decreased in treated patients compared to before treatment. [karger.com]
Research on treatment modalities is ongoing. [medical-dictionary.thefreedictionary.com]
The medicines will usually be tested against another treatment called a control. This will either be a dummy treatment (a placebo) or a standard treatment already in use. [nhs.uk]
Once we've approved your claim, you'll get the private treatment you need. 3 And we’ll pay for treatment After you've been treated, send us your invoices. [aviva.co.uk]
Prognosis
Prognosis of polycythemia Rubra Vera Mostly prognosis is good and the median survival is 10 to 16 years. The major complications are thrombosis and hemorrhage. [labpedia.net]
Prognosis If you have PV, your prognosis depends on many factors including your age, other illnesses you have, and PV complications you may develop with PV. [mpnvoice.org.uk]
Polycythemia Vera prognosis: Chronic disease- patient lives 10-20 years with therapy. In 15-20% of patients, after about 10 years the disease gives rise to a "spent" stage. Life expectancy is then about 3 years. Bone marrow becomes fibrotic. [quizlet.com]
Prognosis Curing or removing the underlying cause of this disorder generally eliminates the symptoms. Resources OTHER "Secondary Erythrocytosis." The Merck Page. June 3, 1998. 〈 http://www.merck.com 〉. [encyclopedia.com]
Etiology
There are two distinct forms of the disease: Primary polycythemia (polycythemia vera) is a myeloproliferative disorder of unknown etiology. [medical-dictionary.thefreedictionary.com]
PV is a disorder of unknown etiology involving a multipotent hematopoietic progenitor cell that is characterized by the accumulation of phenotypically normal red blood cells, white blood cells, and platelets in the absence of a definable cause; extramedullary [raysahelian.com]
Leopold SS: The etiology of pulmonary arteriosclerosis (Ayerza’s syndrome). Am J Med 219:152, 1950. 9. Abbott ME: Atlas of Congenital Heart Disease. American Heart Association, New York, 1936. 10. [medtextfree.wordpress.com]
Subjects with any active medical illnesses that could be etiologically related to the ongoing depressive episode (e.g. untreated hypothyroidism, cardiovascular accident within the past 6 months, uncontrolled hypertension or diabetes), and who were pregnant [journals.plos.org]
Epidemiology
The February 2009 issue of Cancer Epidemiology, Biomarkers and Prevention article, reported on by Newswies.com pointed to the connection between environmental toxins and the number of people affected by this rare disease. [glutathionediseasecure.com]
Epidemiology The frequency of secondary polycythemia depends on the underlying disease. The mortality and morbidity of secondary polycythemia depend on the underlying condition. Tefferi A, Barbui T. [emedicine.medscape.com]
Modan B: An epidemiological study of polycythemia vera. Blood 26:657, 1965. 30. Berglund S, Zettervall O: Incidence of polycythemia vera in a defined population. Eur J Haematol 48:20, 1992. 31. [medtextfree.wordpress.com]
Pathophysiology
Stress polycythemia--a pathophysiologic study M K El-Yousef et al. South Med J. 1975 May. [pubmed.ncbi.nlm.nih.gov]
Some factors that possibly could play a role in the pathophysiology of this syndrome were ruled out and other factors not studied here were considered for future investigation. [ncbi.nlm.nih.gov]
A case report. ( 7661388 ) 1995 2 Stress polycythemia. ( 3837011 ) Mehta B.C. 1985 3 Stress polycythemia. ( 3997770 ) Nanavati N.J....Nihalani K. 1985 4 Stress polycythemia--a pathophysiologic study. ( 165576 ) El-Yousef M.K....Bakewell W.E. 1975 5 Stress [malacards.org]
Sections of the Handbook include History of Hemorheology; Hemorheology, covering basic aspects, blood composition, blood rheology, cell mechanics, pathophysiology, methods and comparative studies; Hemodynamics, covering basic principles, microcirculation [books.google.com]
Prevention
The major goal of the treatment is to prevent thrombotic complications and haemorrhages. The amount of red blood cells is kept within the normal range (haematocrit < 0.45, haemoglobin < 145 g/l). This prevents cardiovascular deaths and thromboses. [books.google.de]
Therapy must also include appropriate measures to prevent continuing fluid loss. [doctor-clinic.org]
The important question now: Is there a treatment, are there preventative steps to take and what are they. The Science of the Disease To look for a cure, treatment, or how to prevent it will require looking at the science behind it. [glutathionediseasecure.com]
prevent blood clots and reduce the risk of serious complications. [nhs.uk]
Treatment options include the following: Phlebotomy Chemotherapy Aspirin Prevention There are no known preventative measures that will reduce your chances of getting primary polycythemia; the condition is not contagious. [cancer.uvahealth.com]