Butterworth-Heinemann, ٢٢‏/١٠‏/٢٠١٣ - 1300 من الصفحات Stress in Health and Disease presents the principal pathways mediating the response to a stressor. It discusses the clinical background of cross-resistance and treatment with stress-hormones. [books.google.com]

A case of stress polycythemia without symptoms of cerebral ischemia is presented. [ncbi.nlm.nih.gov]

Splenomegaly absent absent present in 75% of the cases 9. Hepatomegaly absent absent present in 35% of the cases 10. Heart or lung disease absent present absent 11. Cyanosis may be present present absent Possible References Used Back to tests [labpedia.net]

A summary on this disease is available in Deutsch (2007) Español (2007) Français (2007) Italiano (2007) Nederlands (2007) The documents contained in this web site are presented for information purposes only. [orpha.net]

One half of the patients studied in the present series, and 47% of those previously reported had severe cardiovascular disease; 71% of the latter patients also had arterial hypertension. [jamanetwork.com]

• Fatigue

  We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition. Last updated: January 31, 2019 [patientslikeme.com]

  On this subject I am 24 and having severe concentration problems fatigue and memory issues so bad currently right now that I cant even enjoy life to its fullest extent dating friends etc. [curezone.org]

  Fatigue and headache were common, and syncopal attacks occurred in four patients. [nejm.org]

  Assessment The patient with spurious polycythemia usually has no specific signs or symptoms but may have vague complaints, such as headache, dizziness, and fatigue. Less commonly, the patient may report diaphoresis, dyspnea, and claudication. [nursekey.com]

  […] bleeding due to a cut or a nosebleed Intense and frequent bone pain and/or muscle pain Headaches, lightheadedness or gastrointestinal symptoms Vision problems Ringing in the ears Difficulty or labored breathing The color of the skin appears reddish Fatigue [cancer.uvahealth.com]

• Hypoxemia

  Introduction In adult defined by a Hct > 55% Most common cause is chronic hypoxemia secondary to lung disease Causes of Secondary Polycythemia Hypoxemia COPD Restrictive lung disease Cyanotic congenital heart High altitude Ectopic erythopoeitin Renal [medbullets.com]

  ABG revealed hypoxemia with pO2 (33.9 mmhg). [medicaldialogues.in]

  ABG showed hypoxemia with pO2 (33.9 mmhg). Other blood studies, including blood u r e a n i t r o g e n, c r e a t i n i n e, electrolytes, liver chemistries and thyroid stimulating hormone were within normal limits. [japi.org]

  The finding of significant hypoxemia in the supine position in all patients in this study suggests that postural hypoxemia may be a frequent cause of an elevated red cell volume. [amjmed.com]

  Prep4USMLE.com Advertisement usmleasr Forum Guru Topics: 105 Posts: 970 Mar 01, 2004 - 2:44 PM #2 high altitude, COPD, and any cause of hypoxemia asmi Forum Hero Topics: 1049 Posts: 4620 Mar 01, 2004 - 3:33 PM #3 you forgot DIURETICS gr_calif Forum Junior [prep4usmle.com]

• Plethora

  Andral1 in 1843 observed that plethora is more frequently constitutional than acquired. [jamanetwork.com]

  Angiology 29(7): 520-533 1978 ISSN/ISBN: 0003-3197 PMID: 686487 DOI: 10.1177/000331977802900703 Accession: 040191146 The syndrome of plethora without splenomegaly, leukocytosis, or thrombocytosis was described by Gaisböck in 1905. [eurekamag.com]

  […] stenosis) hepatic lesions (hepatocellular carcinoma, cirrhosis) endocrine tumours (EPO secreting) other tumours (bronchial tumours) androgens Relative (decreased plasma volume) dehydration (diuretics and alcohol), stress polycythaemia CLINICAL FEATURES plethora [lifeinthefastlane.com]

  Abstract The syndrome of plethora without splenomegaly, leukocytosis, or thrombocytosis was described by Gaisböck in 1905. It was reevaluated in 25 patients through the study of numerous hematologic and biochemical parameters. [pubmed.ncbi.nlm.nih.gov]

  Their face may have a marked reddish-blue colour (plethora). This is particularly obvious on the lips, cheeks, ears and tip of the nose. The hands and feet may have a similar coloration. Bruising and a tendency to bleed are also common. [mydr.com.au]

• Falling

  High-dose diuretic therapy, for example furosemide (frusemide) given in a dose of 400 mg or more daily, will contract the plasma volume; when the diuretics are discontinued, the hematocrit may fall within hours from, say, 0.65 to 0.50. [alpfmedical.info]

  Erythrocytosis due to tobacco use or abuse Erythrocytosis secondary to tobacco use Erythrocytosis secondary to tobacco use or abuse Secondary polycythemia 289.0 Excludes Applies To High-oxygen-affinity hemoglobin Polycythemia: acquired benign due to: fall [icd9data.com]

  Applicable To Acquired polycythemia Emotional polycythemia Erythrocytosis NOS Hypoxemic polycythemia Nephrogenous polycythemia Polycythemia due to erythropoietin Polycythemia due to fall in plasma volume Polycythemia due to high altitude Polycythemia [icd10data.com]

  This occurs when peripheral chemoreceptors, situated in the aortic and carotid bodies, detect the falling arterial pO2 and hence increase the respiratory rate. [teachmephysiology.com]

• Congestive Heart Failure

  heart failure, occurring due to hypobaric hypoxia-anoxia-induced erythropoiesis reported in both native mountain residents and new climbers after prolonged stays at high and extreme altitudes. [ijtmgh.com]

  Other therapies can be directed toward treating the cause of polycythemia (for example, appropriate treatment of heart failure or chronic lung disease). [emedicinehealth.com]

  ( congestive heart failure, or abnormal flow of blood from the right side to the left side of the heart), sleep apnea, and pulmonary hypertension. [rxlist.com]

  (congestive heart failure, or abnormal flow of blood from the right side to the left side of the heart), sleep apnea, and pulmonary hypertension. [medicinenet.com]

  Portal hypertension and varices are not uncommon.111 The incidence of peptic ulcer is four to five times as great as in the general population.112 CARDIOVASCULAR Cardiovascular symptoms include angina, myocardial infarction, and congestive heart failure [medtextfree.wordpress.com]

• Hypertension

  Gaisböck syndrome (redirected from Gaisbock syndrome) pol·y·cy·the·mi·a hy·per·to·n'i·ca polycythemia associated with hypertension, but without splenomegaly. [medical-dictionary.thefreedictionary.com]

  male sex, smoking and diuretic therapy; of these, hypertension appears to be the most significant contributor to the polycythemia of Gaisbock’s syndrome.2 In this regard, Emamian and associates studied 9,808 individuals with essential hypertension and [japi.org]

  Our patient had four risk factors for Gaisbock's syndrome - hypertension, diuretic therapy, physical and emotional stress, and obesity; of these, hypertension (particularly diastolic hypertension) appears to be the most significant contributor to the [clinmedjournals.org]

  This patient had four risk factors for Gaisbock's syndrome: hypertension, male sex, smoking, and diuretic treatment; of these, hypertension appears to be the most important contributor to Gaisbock's syndrome polycythemia. [medicaldialogues.in]

  One half of the patients studied in the present series, and 47% of those previously reported had severe cardiovascular disease; 71% of the latter patients also had arterial hypertension. [jamanetwork.com]

• Heart Failure

  It outlines new guidelines on specific clinical conditions such as heart failure, management of female infertility, specific lipid monitoring in diabetes and guidance for monitoring renal failure. [books.google.de]

  ( congestive heart failure, or abnormal flow of blood from the right side to the left side of the heart), sleep apnea, and pulmonary hypertension. [rxlist.com]

  (congestive heart failure, or abnormal flow of blood from the right side to the left side of the heart), sleep apnea, and pulmonary hypertension. [medicinenet.com]

  failure, occurring due to hypobaric hypoxia-anoxia-induced erythropoiesis reported in both native mountain residents and new climbers after prolonged stays at high and extreme altitudes. [ijtmgh.com]

  Other therapies can be directed toward treating the cause of polycythemia (for example, appropriate treatment of heart failure or chronic lung disease). [emedicinehealth.com]

• Upper Back Pain

  These include: pain, swelling, redness and tenderness in one of your legs a heavy ache in the affected area warm skin in the area of the clot breathlessness chest or upper back pain coughing up blood feeling lightheaded or dizzy fainting Polycythaemia [nhs.uk]

• Flushing

  She also noted the occurrence of flushing of her face and swelling and flushing of the soles of her feet. Her past medical history was notable for hypertension, a multinodular thyroid, and mild IgM deficiency. [clinmedjournals.org]

  The elevated blood cell mass results in hyperviscosity, which may manifest with fatigue, facial flushing, pruritus, erythromelalgia, headaches, dizziness, and, in severe cases, thromboembolic events (e.g., stroke, Budd-Chiari syndrome). [www-amboss-com.db.rsu.lv]

  Now my symptoms as you know were Severe Fatigue, Severe Facial Flushing, Very fast heart rate, confusion and drowsiness, Memory Problems, Short term memory loss. ------------------------------------------------------- Verifiable sources: (I will put quotes [curezone.org]

  Weakness, fatigue, headache, blood clotting, vertigo, tinnitus, irritability, dyspnea, visual disturbances, flushing of face, redness, or ruddy cyanosis, pruritus, ecchymosis, hypertension, epigastric distress, weight loss, and pain in joints or extremities [medical-dictionary.thefreedictionary.com]

• Chronic Anxiety

  Behavioral/emotional stress and chronic anxiety have been shown to cause changes in hemorheologic measures, possibly due to increases in catecholamines and blood pressure [18]. [journals.plos.org]

• Malar Rash

  rash Discoid rash With pregnancy there is an increased incidence of pre-eclampsia, uterine infection, SAb, prematurity, IUGR, congenital heart bloack and endomyocardial fibrosis. [pathologyexpert.com]

• Headache

  One visible symptom of polycythemia vera are headaches, according to this research from the National Institutes of Health. By reducing blood flow to the brain, painful headaches can become quite common. [activebeat.com]

  This may cause sluggishness, irritability, headache, dizziness, fainting, disturbances of sensation in the hands and feet, and a feeling of fullness in the head. There may be episodes of acute pain as spontaneous clots occur in the blood vessels. [medical-dictionary.thefreedictionary.com]

  Fatigue and headache were common, and syncopal attacks occurred in four patients. [nejm.org]

  Assessment The patient with spurious polycythemia usually has no specific signs or symptoms but may have vague complaints, such as headache, dizziness, and fatigue. Less commonly, the patient may report diaphoresis, dyspnea, and claudication. [nursekey.com]

  Symptoms may include: Abnormal and heavy bleeding due to a cut or a nosebleed Intense and frequent bone pain and/or muscle pain Headaches, lightheadedness or gastrointestinal symptoms Vision problems Ringing in the ears Difficulty or labored breathing [cancer.uvahealth.com]

• Dizziness

  He noted that plethoric people may have an increased quantity of "globules" in the blood and that some of these persons have peculiar symptoms including vertigo and dizziness. But not all plethoric persons have elevated concentrations of hemoglobin. [jamanetwork.com]

  When left untreated, these headaches can intensify, leading to dizziness, lightheadedness, and overall feelings of weakness. If these feelings become a part of your daily routine, be sure to talk to your doctor. ADVERTISEMENT [activebeat.com]

  Assessment The patient with spurious polycythemia usually has no specific signs or symptoms but may have vague complaints, such as headache, dizziness, and fatigue. Less commonly, the patient may report diaphoresis, dyspnea, and claudication. [nursekey.com]

  These include: headaches blurred vision red skin – particularly in the face, hands and feet tiredness high blood pressure dizziness discomfort in the tummy confusion bleeding problems – such as nosebleeds and bruising gout – which can cause joint pain [nhs.uk]

  Polycythemia Vera clinical features: Face appears suffused with blood, retinal veins are engorged, frequent headaches, dizziness, blurred vision and tinnitus. [quizlet.com]

• Lethargy

  With further increases, the patient may develop central nervous system symptoms, such as forgetfulness, lethargy, or headache, and may have signs of excess cardiac preload, such as distended neck veins and hepatic congestion. [accessmedicine.mhmedical.com]

  These included “feeding problems” (21.8%), plethora (20.0%), lethargy (14.5%), cyanosis (14.5%), respiratory distress (9.1%), jitteriness (7.3%), and hypotonia (7.3%). Other findings included hypoglycemia (40.0%) and hyperbilirubinemia (21.8%). [medtextfree.wordpress.com]

• Agitation

  She is agitated and complains of substernal chest pain. Chest exam reveals few bibasilar crackles. Cardiac, abdominal, and extremity exams are normal except for her surgical wounds, which seem to be healing well. [drsami.com]

A workup revealed no evidence of polycythemia rubra vera or a secondary cause of his polycythemia (his erythropoietin level was normal, he had no splenomegaly, and a test for JAK2 v617F mutation was negative). [plexusmd.com]

The initial workup of erythrocytosis is dependant on the probability of polycythemia vera as the underlying cause. A serum erythropoietin level is usually the first step. [thebigl.co]

However, it has never been shown that an exhaustive workup for malignancy is cost-effective or beneficial. [drsami.com]

A workup revealed no evidence of polycythemia rubra vera or a secondary cause of her polycythemia (her erythropoietin level was normal, she had no splenomegaly, and a test for JAK2 v617F mutation was negative). [clinmedjournals.org]

• Erythrocytosis

  [Felix Gaisböck, Ger. physician, 1869–1955] Benign erythrocytosis. [medical-dictionary.thefreedictionary.com]

  Chronic relative polycythemia or erythrocytosis has been variously called Gaisbock syndrome, stress erythrocytosis, benign polycythemia or erythrocytosis, benign erythrocytosis, spurious polycythemia, pseudopolycythemia, or apparent polycythemia. [enotes.tripod.com]

  Called also benign or stress erythrocytosis, Gaisbцck disease, pseudopolycythemia, and benign, chronic relative, hypertonic, or spurious p. Medical dictionary. 2011. [medicine.academic.ru]

• Decreased Plasma Volume

  — The "Gaisböck Syndrome," although considered by some as a "nonentity," has the specific hematologic findings of an apparent polycythemia, a normal circulating red blood cell (RBC) mass, and a decreased plasma volume. [jamanetwork.com]

  Since the Hct is a ratio between the number of circulating RBCs per unit volume of whole blood, an elevated Hct may be caused by a decreased plasma volume. Thus, true erythrocytosis is based on demonstrating an increased RBC mass. [163.178.103.176]

  Nervous stress leads to hemoconcentration by some unknown mechanism, possibly by temporarily decreasing circulating plasma volume or by vascular redistribution of erythrocytes. high normal RBC mass and low normal plasma volume. [doctor-clinic.org]

  Relative/pseudo polycythaemia occurs due to decreased plasma volume. This may occur due to dehydration (eg vomiting, diarrhoea, diuretics) A special form of relative polycythaemia is Gaisbocks. [mrcpandme.blogspot.com]

Treatment is now actively pro moted by public health agencies, including the World Health Organization. This is an other case of treatment preceding full understanding of the nature of the disease. [books.google.de]

The team concluded that treatment should involve strict hypertension control, avoidance of diuretic treatment, smoking cessation, and, in obese patients, the implementation of a strong weight reduction plan. [medicaldialogues.in]

The medicines will usually be tested against another treatment called a control. This will either be a dummy treatment (a placebo) or a standard treatment already in use. [nhs.uk]

After 6 months of treatment, the TOS, OSI and MDA levels were significantly decreased in treated patients compared to before treatment. [karger.com]

Prognosis Prognosis is impaired by the development of cardiovascular complications. [orpha.net]

Prognosis of polycythemia Rubra Vera Mostly prognosis is good and the median survival is 10 to 16 years. The major complications are thrombosis and hemorrhage. [labpedia.net]

Prognosis If you have PV, your prognosis depends on many factors including your age, other illnesses you have, and PV complications you may develop with PV. [mpnvoice.org.uk]

Polycythemia Vera prognosis: Chronic disease- patient lives 10-20 years with therapy. In 15-20% of patients, after about 10 years the disease gives rise to a "spent" stage. Life expectancy is then about 3 years. Bone marrow becomes fibrotic. [quizlet.com]

Excerpt Although the etiology of polycythemia vera remains unknown, repeated attempts have been made to correlate the condition with some cardiovascular phenomenon. [acpjournals.org]

Secondary etiologies for hypertension evaluating for renal artery stenosis, Coarctation of the aorta, hyperaldosteronism, and Pheochromocytoma were all unrevealing. [asn-online.org]

There are two distinct forms of the disease: Primary polycythemia (polycythemia vera) is a myeloproliferative disorder of unknown etiology. [medical-dictionary.thefreedictionary.com]

Table 12-1 presents an etiologic framework based on different mechanisms responsible for the expansion of the red cell mass. [accessmedicine.mhmedical.com]

Finally, the etiology of secondary polycythemia has to be ascertained. A certain number of patients cannot be easily classified as having either PV or secondary polycythemia due to diagnostic difficulties. [pathology.medresearch.in]

Summary Epidemiology It occurs mainly in male sedentary individuals, on a high-calorie diet. Prevalence is unknown. [orpha.net]

ORIGINAL PAPERS: Epidemiology results from the national inpatient sample database Krishnamoorthy, Parasurama; Gopalakrishnan, Akshayaa; Mittal, Varunb; Kalla, Aditia; Slipczuk, Leandroa; Rangaswami, Jananic; Figueredo, Vincent M.a; Messerli, Franz H.d [journals.lww.com]

Gaisbock Syndrome: A Rare Etiology of Secondary Hypertension Session Information Hypertension and CVD: Epidemiology, Risk Factors, Prevention November 03, 2022 | Location: Exhibit Hall, Orange County Convention Center‚ West Building Abstract Time: 10: [asn-online.org]

Epidemiology Epidemiological data refers to the US, unless otherwise specified. Pathophysiology The JAK2 (Janus kinase 2) oncogene codes for a non-receptor tyrosine kinase in hematopoietic progenitor cells. [amboss.com]

Stress polycythemia--a pathophysiologic study M K El-Yousef et al. South Med J. 1975 May. [pubmed.ncbi.nlm.nih.gov]

Some factors that possibly could play a role in the pathophysiology of this syndrome were ruled out and other factors not studied here were considered for future investigation. [ncbi.nlm.nih.gov]

Pathophysiology: Pituitary shut-down of FSH and LH production. Micro: Atrophic vaginal smear. [pathologyexpert.com]

A case report. ( 7661388 ) 1995 2 Stress polycythemia. ( 3837011 ) Mehta B.C. 1985 3 Stress polycythemia. ( 3997770 ) Nanavati N.J....Nihalani K. 1985 4 Stress polycythemia--a pathophysiologic study. ( 165576 ) El-Yousef M.K....Bakewell W.E. 1975 5 Stress [malacards.org]

However, no physiologic or pathologic basis has been found.In our study, which was designed to elicit the pathophysiology of this entity, two typical cases were studied. [jamanetwork.com]

The major goal of the treatment is to prevent thrombotic complications and haemorrhages. The amount of red blood cells is kept within the normal range (haematocrit < 0.45, haemoglobin < 145 g/l). This prevents cardiovascular deaths and thromboses. [books.google.de]

Therapy must also include appropriate measures to prevent continuing fluid loss. [doctor-clinic.org]

The important question now: Is there a treatment, are there preventative steps to take and what are they. The Science of the Disease To look for a cure, treatment, or how to prevent it will require looking at the science behind it. [glutathionediseasecure.com]

prevent blood clots and reduce the risk of serious complications. [nhs.uk]

Treatment options include the following: Phlebotomy Chemotherapy Aspirin Prevention There are no known preventative measures that will reduce your chances of getting primary polycythemia; the condition is not contagious. [cancer.uvahealth.com]