A 17-year-old girl with systemic lupus erythematosus presented with painful edematous abdominal striae. She had been treated with systemic steroid for the systemic lupus erythematosus. [ncbi.nlm.nih.gov]

• Rigor

  There is a clear need for robust, methodologically rigorous randomised trials involving larger sample sizes to evaluate the effects of topical preparations on the development of stretch marks in pregnancy. [ncbi.nlm.nih.gov]

  Furthermore, available topical modalities generally lack strong evidence from rigorous, well‐designed, randomized controlled trials with ample numbers of subjects. [doi.org]

• Turkish

  Articles in English, Spanish, Portuguese, Turkish and French were included. Striae distensae occur in pregnancy, puberty and obesity as well as in numerous medical conditions and following therapeutic interventions. [ncbi.nlm.nih.gov]

  Complementary and alternative medicine use among Turkish diabetes patients. Complement Ther Med. 2009;17(2):78. 30. Namjoyan F, Kiashi F, Moosavi ZB, Saffari F, Makhmalzadeh BS. [dovepress.com]

• Disability

  Widely spread striae are not a serious disease or disability, but only a cosmetic problem. However, they may lead to a persistent complex and feeling of inferiority or even cause serious depression states, especially in teenagers, as in this case. [ncbi.nlm.nih.gov]

  Widely spread striae are not a serious disease or disability, but only a cosmetic problem. [semanticscholar.org]

  Immunosupressives are indicated when the disease is disabling.[2] Cyclosporine is a steroid-sparing drug found to be effective in autoimmune urticarial through the inhibition of release of histamine from basophils in patients of chronic urticaria with [cdriadvlkn.org]

• Easy Bruising

  Rarely, striae can result from an underlying condition Cushing's syndrome (obesity with distribution around the abdomen and trunk causing a 'buffalo hump' between the shoulders, and the face leading to the development of a 'moon face' / thin skin with easy [pcds.org.uk]

• Prolapse

  and pelvic prolapse (2) Immunosuppression states: HIV, TB, and typhoid Other medical conditions: Cushing syndrome, rheumatic fever, anorexia nervosa, chronic liver disease, obesity Surgery: breast augmentation, tissue-expanded skin, organ transplantation [unboundmedicine.com]

  Read More Download full-text PDF Source DOI Listing The Association of Abdominal Striae With Pelvic Organ Prolapse. [pubfacts.com]

  Tasyurt, Can striae be used as a marker for the prediction of pelvic organ prolapse?, European Journal of Obstetrics & Gynecology and Reproductive Biology, 180, (116), (2014). [doi.org]

• Eczema

  […] striae distensae, click HERE ) Systemic steroids are known to induce purplish stretch marks as part of Cushing’s syndrome ( more HERE ) Topical steroids have anti-inflammatory action and are used in the treatment of inflammatory skin diseases such as eczema [genevadermatology.ch]

  Relapsing polychondritis 673 211 Rhinophyma 677 212 Rocky Mountain spotted fever and other rickettsial infections 679 213 Rosacea 684 214 Sarcoidosis 692 215 Scabies 697 216 Scleredema 700 217 Scleroderma 703 218 Sebaceous hyperplasia 707 219 Seborrheic eczema [books.google.de]

  […] atopicum (dermatitis atopica) Subacute and chronic (eczem) dermatitis Microbial eczema Granuloma gluteale infantum Toxic contact (irritative) dermatitis, acute Toxic contact (irritative) dermatitis, chronic Seborrhoic dermatitis Pityriasis amiantacea [atlases.muni.cz]

  Ehlers-Danlos syndrome, or Marfan’s syndrome growth spurt in puberty rapid weight loss or gain weight training with rapid muscle growth If you use corticosteroid creams for an extended time period, such as prescription-strength hydrocortisone to treat eczema [healthline.com]

  […] to Van Scott and Yu discloses the use of alpha hydroxy acids for treatment of skin irritating or scalp related conditions, such as dry skin, ichthyosis, hyperkeratosis, dandruff, Darier's disease, lichen simplex chronicus, keratoses, acne, psoriasis, eczema [patents.google.com]

• Koebner Phenomenon

  Koebner phenomenon, the appearance of preexisting skin lesions following trauma to previously uninvolved skin, has been seen frequently with vitiligo. [ncbi.nlm.nih.gov]

  Clindamycin-induced Maculopapular Exanthema with Preferential Involvement of Striae Distensae: A Koebner phenomenon? Acta Dermatovenerol Croat. 2018;26:61-3. Happle R, Kluger N. [adc.mef.hr]

  Koebner’s phenomenon in vitiligo: European position paper. Pigment Cell Melanoma Res 2011;24:564-73. 2. van Geel N, Speeckaert R, De Wolf J, Bracke S, Chevolet I, Brochez L et al. Clinical significance of Koebner phenomenon in vitiligo. [pigmentinternational.com]

  Vitiligo appearing in striae distensae as a Koebner phenomenon. J Coll Physicians Surg Pak 2009;19:796–797. Hermanns JF, Piérard GE. High-resolution epiluminescence colorimetry of striae distensae. J Eur Acad Dermatol Venereol 2006;20:282–287. [synapse.koreamed.org]

• Cutaneous Manifestation

  To the best of our knowledge, this cutaneous manifestation of lupus erythematosus has not been previously reported. Koebner's phenomenon is suspected to be the underlying mechanism. [ncbi.nlm.nih.gov]

  Volc-Platzer, Hautmanifestationen beim metabolischen Syndrom Cutaneous manifestations of metabolic syndrome, Der Hautarzt, 10.1007/s00105-016-3891-2, 67, 12, (982-988), (2016). [doi.org]

  Am Fam Physician 75(2): 211–8 Google Scholar Walter K (2009) Cutaneous Manifestations of Endocrine Diseases. Springer-Verlag, Berlin Google Scholar Waterhouse N (2008) Cosmetic Surgery (The Facts). [magonlinelibrary.com]

• Large Breast

  breasts or breast implants, and pregnancy. [medicinenet.com]

• Hyperactivity

  Poidevin 1959 proposed the existence of a 'striae factor' for each woman and while not identifying what this 'striae factor' may be, he found a clear relationship between the reduced glucose tolerance in pregnancy, a sign of adrenocortical hyperactivity [doi.org]

In patients presenting with striae distensae due to pubertal growth ’spurt’, increase in weight, pregnancy, and/or corticosteriod abuse, no further workup is required. [dermatologyadvisor.com]

Figure 1: (a) Flowchart for management of striae distensae pre-treatment workup. [idoj.in]

• Bartonella Henselae

  None of the boys had a history of unmonitored exogenous steroid use or prior infection with Bartonella henselae or Borrelia burgdorferi. Only one (8.3%) had a chronic medical condition. [ncbi.nlm.nih.gov]

• Borrelia Burgdorferi

  None of the boys had a history of unmonitored exogenous steroid use or prior infection with Bartonella henselae or Borrelia burgdorferi. Only one (8.3%) had a chronic medical condition. [ncbi.nlm.nih.gov]

Lesions were randomized to receive treatment, with site-matched normal control areas. Patients received a total of 6 treatments using a 1550-nm, erbium-doped fiber laser with 2 to 3 weeks of elapsed time between treatments. [ncbi.nlm.nih.gov]

Abstract Full HTML Article PDF ecancer 11 756 / Case Report Glioblastoma cerebri is a rare paediatric malignancy with dismal prognosis [Chappé C, Riffaud L, and Tréguier C et al (2013) Primary gliomatosis cerebri involving gray matter in pediatrics: a [ecancer.org]

What is the prognosis of stretch marks? As the striae mature, they become less apparent but they rarely disappear. They do not cause any health problems. [medicinenet.com]

The experience of 20 patients with striae distensae of varying etiologies and the treatment with topical tretinoin is described. Of the 16 patients who completed the study, 15 had significant improvement in their clinical picture. [ncbi.nlm.nih.gov]

[…] and Pathophysiology Specific etiology of SD is unknown. [unboundmedicine.com]

One of four possible etiologic mechanisms usually considered were: (1) insufficient development of the integuement, including a deficiency in its elastic properties; (2) rapid stretching of the skin; (3) endocrine imbalance; and (4) other, possibly toxic [jamanetwork.com]

A number of key etiological theories have been postulated, including: Inadequate development of elastic fibers and collagen in the skin Endocrine imbalance and physical stretching of the skin due to increased size of any part of the body ex. [dermclub.org]

The etiology likely involves the interplay of mechanical stress, hormones, and genetics. Striae are commonly located on the abdomen, thighs, and buttocks, or in areas where the skin stretches excessively. [visualdx.com]

EPIDEMIOLOGY AND RISK FACTORS Epidemiologic data on striae distensae in the general population are limited [ 1-11 ]. Reported incidences have ranged from as low as 11 percent in normal men to up to 88 percent in pregnant females [ 5,11 ]. [uptodate.com]

Risk factors have been reported but much remains to be understood about their epidemiology, diagnosis and treatment. [scinapse.io]

To better characterize the epidemiological factors associated with SG. An anonymous survey administered at Stanford Ambulatory Clinics sampled 161 women who had given birth. [ncbi.nlm.nih.gov]

BACKGROUND: Despite the high prevalence of striae distensae, clinical studies are few in number, and their pathophysiology still obscure. [ncbi.nlm.nih.gov]

This chapter will address the pathophysiology and risks associated with the development of striae in the context of the above conditions as well as review preventive measures and known treatments. [miami.pure.elsevier.com]

She published more than 100 Publications and she is the editor of 4 medical books (Cosmetic Use of Botulinum Toxin, Botulinum Toxin and Hyperhidrosis, Cosmetic Procedures in Etnic Patients, and, two editions of the book Cellulite: Pathophysiology and [books.google.de]

Etiology Pathophysiology Striae distensae results from cracks in the connective tissue forming atrophic dermal scars underneath an atrophic epidermal layer. The pathophysiology of striae distensae is not fully understood. [dermatologyadvisor.com]

Finally, cocoa butter and olive oil are not effective for preventing SG or reducing the severity of lesions. We conclude that reliable methods for preventing SG are scarce. [doi.org]

Fletcher and Marvin Reid, Prevention of striae gravidarum with cocoa butter cream, International Journal of Gynecology & Obstetrics, 108, 1, (65-68), (2009). [dx.doi.org]

Use of a specific anti-stretch mark cream for preventing or reducing the severity of striae gravidarum. Randomized, double-blind, controlled trial. International Journal of Cosmetic Science. 2013;35:233. Brennan M, et al. [mayoclinic.org]