This case suggests that the hyperthermia of NMS is due to peripheral heat production associated with severe muscular rigidity secondary to withdrawal of striatal dopamine drive, rather than being centrally mediated by the hypothalamus, which is not involved [ncbi.nlm.nih.gov]

Also, neurodegenerative conditions such as Alzheimer's disease, Parkinson's disease, or multiple system atrophy are frequency associated with primary hypersomnia. [diki.pl]

Highlights of this edition include over 6,800 images of remarkable quality, more color images, and new information using advanced techniques, including perfusion and diffusion MRI and functional MRI. [books.google.com]

CBS (CBD) is a progressive condition meaning that symptoms worsen over time. Cortico Basal – refers to the parts of the brain affected. The cortex is the outer layer of the brain and the basal ganglia lies deeper in the brain. [parkinsonsnsw.org.au]

For this reason we do not think that differences in initial motor compromise had any effect on the mean cognitive changes over time. [jnnp.bmj.com]

It is important to note that these manifestations may occur in various combinations and may also evolve over time. [ndrf.org]

Striatonigral Degeneration Striatonigral degeneration is similar to Parkinson's disease, except tremor is much less common, and cerebellar ataxia (failure of muscle coordination) often develops over time. [healthcommunities.com]

She also had auditory hallucinations. MRI revealed hypointense T2 signals in the putamina and substantia nigra. T1-weighted MRI demonstrated atrophy of both the pons and cerebellum in addition to atrophy of the putamina and substantia nigra. [ncbi.nlm.nih.gov]

The autonomic failure symptoms include the following: Orthostatic Hypotension Including: Lightheadedness Tiredness Blurred Vision Ataxia ( Failure of Muscular Coordination) Pain in the Rear of the Neck Mild Cognitive Impairment occurs in about 20% of [ndrf.org]