Enzymatic hydrolysis of K-strophanthoside using the enzymes- glucosidase, usually present in yeast, helps in cleaving off the terminal a-D glucose thereby yielding the secondary glycoside known as K-strophanthidin b. [epharmacognosy.com]

Two cases of Nerium Oleander poisoning were presented. Clinical picture included gastrointestinal, cardiovascular and central nervous system effects. [content.sciendo.com]

Presented by Médi-T STROPHANTHUS HISPIDUS Kombe-seed Strophanthus is a muscle poison; it increases the contractile power of all striped muscles. Acts on the heart; increasing the systole and diminishes the rapidity. [homeoint.org]

The drinker is not permitted to be present at the preparation of the mboundou, but he may send two friends to see that all is fair. " When Olanga came he emptied the bowl at a draught In about five minutes the poison took effect. He... ‏ [books.google.com]

Strophanthin is present in species of the African genus Strophanthus. It belongs to the family Apocynaceae, which also contains the plants that yield the Vinca alkaloids and reserpine. [heart.bmj.com]

• Sore Throat

  throat, dizziness and nausea, then muscular fatigue, low body temperature, hypotension, teeth clenching, foaming saliva, stomach ache, weak heartbeat and mydriasis and finally a quick death due to apnea. [vietnamheritage.com.vn]

• Dry Cough

  When admitted he had a frequent, short, dry cough, worse lying down, had to be propped up in bed, had oedema of feet, especially left. [homeopathycenter.org]

• Overeating

  It has the great advantage over digitalis of being non-cumulative, and can be administered continually for many weeks or even months at a time. [theodora.com]

  Payment details Payment methods Special financing available Select PayPal Credit at checkout to have the option to pay over time. Qualifying purchases could enjoy No Interest if paid in full in 6 months on purchases of $99 or more. [ebay.com]

  Plants are the origin of 36 cardiac glycosides being found in over 40 species contained within 36 genera and 11 families. [heart.bmj.com]

  Zimbabwe distribution: C,E Growth form(s): Climber, liane, shrub over 2 m. [zimbabweflora.co.zw]

  Update: The summer is over and it's getting cold outside so it came back it. It did VERY well outside. It dropped nearly all it leaves but put them back on much lusher. [davesgarden.com]

• Heart Block

  The clinical symptoms were characterized by nausea, vomiting, salivation, colic, diarrhoea, ventricular tachycardia, dysrhythmia, heart block, ataxia, drowsiness, muscular tremor. [content.sciendo.com]

  Cardiac glycosides also have vagotonic effects, resulting in bradycardia and heart block. Inhibition of Na+ -K+ -ATPase in skeletal muscle results in increased extracellular potassium and contributes to hyperkalemia. [emedicine.medscape.com]

• Mydriasis

  […] its toxicity will immediately go into effect-its alkaloids will cause symptoms of thirst, sore throat, dizziness and nausea, then muscular fatigue, low body temperature, hypotension, teeth clenching, foaming saliva, stomach ache, weak heartbeat and mydriasis [vietnamheritage.com.vn]

The plant’s healing properties are extracted from the root, bark The plant is used for the treatment of arthritis, stroke, heart failure, rheumatism. The information provided is not intended to be a substitute for medical treatment. [myspotfinder.com]

Treatment included administration of activated charcoal, symptomatic and supportive care. [content.sciendo.com]

Nausea with special disgust for alcohol and so aids in treatment of dipsomania. Seven drops of tincture. Urinary.-- Increased secretion; scanty and albuminous. Female.-- Menorrhagia; uterine hæmorrhage; uterus heavily congested. [homeoint.org]

Some of the chemicals in the plants are used to produce the drug Ouabain, which was taken as a cardiac stimulant to treat heart failure and sometimes g-strophanthin is advocated as an alternative treatment to more contemporary practices. [en.wikipedia.org]

Pretreatment with reserpine reduces the toxicity of ouabain, while simultaneous treatment increases it. This may well explain the success of the mixture in hunting poisons. [uses.plantnet-project.org]

Age-related differences in incidence AAPCC data from 2015 show the following age breakdowns for plant cardiac glycoside exposure [4] : Infants and children younger than 6 years - 57% Children aged 6-19 years - 18% Adults older than 19 years - 22% Prognosis [emedicine.medscape.com]

Etiology Exposure to plants containing glycosides can occur through ingestion of sap, berries, leaves, blossoms, or seeds, or of teas brewed from plant parts. Plant extracts also have been intentionally injected. [emedicine.medscape.com]

Purple foxglove (Digitalis purpurea) Woolly foxglove (Digitalis lanata) Ouabain (Strophanthus gratus) Lily-of-the-valley (Convallaria majalis) Common oleander (Nerium oleander) Yellow oleander (Thevetia peruviana) Squill or sea onion (Urginea maritima) Epidemiology [emedicine.medscape.com]

Pathophysiology More than 200 naturally occurring cardiac glycosides have been identified. These bind to a site on the cell membrane, producing reversible inhibition of the sodium (Na+)-potassium (K+)-adenosine triphosphatase (ATPase) pump. [emedicine.medscape.com]

[Can the digitalis induced changes of the stress electrocardiogram be prevented by potassium administration?]. Kaiser W, Klepzig H. Kaiser W, et al. Med Klin. 1967 Jun 2;62(22):873-7. Med Klin. 1967. PMID: 5594887 German. No abstract available. [pubmed.ncbi.nlm.nih.gov]

Ouabain is a deadly poison because it binds the sodium potassium pump on the surface of cardiac cells preventing contraction of the heart muscle. [tellmewhyfacts.com]

It must be preserved in tightly-closed containers, adding a few drops of chloroform or carbon tetrachloride from time to time, to prevent attacks by insects. [botanical.com]