Edit concept Question Editor Create issue ticket

Stupor

Obtundation


Presentation

  • […] that in our case the presentation with catatonic stupor may be related to impairment of the cortical GABAergic inhibitory system.[ncbi.nlm.nih.gov]
  • We used the vigilance promoting drug modafinil to prevent such attacks in a case presented with endozepine stupor.[ncbi.nlm.nih.gov]
  • In conclusion, children presenting with recurrent episodes of stupor and EEG fast activity should be evaluated for endozepine levels and can be effectively treated with i.v. flumazenil.[ncbi.nlm.nih.gov]
  • A case of recurrent stupor over two decades is presented with many similarities to previous cases of "endozepine stupor".[ncbi.nlm.nih.gov]
  • Abstract The admission records of 271 long-stay chronic schizophrenic patients, resident in a large psychiatric hospital, were examined in order to identify those who had presented in stupor at the onset of their illness.[ncbi.nlm.nih.gov]
Intravenous Administration
  • However, after intravenous administration of diazepam, the EEG abnormalities improved; indicating that her decreased consciousness was of epileptic etiology, consistent with spike-wave stupor.[ncbi.nlm.nih.gov]
Malnutrition
  • The Wernicke-Korsakoff syndrome and related neurologic disorders due to alcoholism and malnutrition. Philadelphia, Pa: FA Davis; 1989. 142-5. Sechi G, Serra A.[medscape.com]
Abnormal Breathing
  • Stupor can cause the following physical symptoms in addition to mental symptoms: abnormal breathing, such as breathing too slow or fast muscles contracted in abnormal ways pupils that are wider or smaller than normal pupils that don’t react or change[healthline.com]
  • Abnormal breathing patterns can provide clues to which parts of the brain are malfunctioning. Checking responses to painful stimulation can help determine whether parts of the brain and spinal cord are malfunctioning.[merckmanuals.com]
Muscle Rigidity
  • This syndrome is characterized by muscle rigidity, fever, and high blood pressure, as well as changes in mental function (such as confusion and lethargy).[merckmanuals.com]
Asterixis
  • This cortical potential was similar to that observed in patients with asterixis secondary to metabolic or toxic encephalopathies.[ncbi.nlm.nih.gov]
Suggestibility
  • The onset of psychiatric symptoms, closely followed by neurological symptoms, without other possible somatic etiology suggests that HIV itself might precipitate psychosis. The patient was treated successfully with electroconvulsive therapy.[ncbi.nlm.nih.gov]
  • Radioreceptor binding studies showed the presence of a ligand to the central benzodiazepine receptor in plasma and cerebrospinal fluid during the episodes, suggesting a gamma-aminobutyric acid (GABA)ergic system involvement in the origin of the attacks[ncbi.nlm.nih.gov]
  • The history suggests that the analeptic property of amitriptyline induced the 'spike-wave stupor' in this patient.[ncbi.nlm.nih.gov]
  • These observations suggest that stupor may occur as a result of drug interactions after the addition of valproic acid to other antiepileptic drugs.[ncbi.nlm.nih.gov]
  • A diagnostic work-up to define endozepine-induced recurrent stupor is suggested.[ncbi.nlm.nih.gov]
Negativism
  • He had been psychotic for over four weeks and had developed mutism, rigidity, negativism, and posturing (but without fever and without changes in blood and serum parameters) despite neuroleptic therapy, but recovered dramatically from stupor within 40[ncbi.nlm.nih.gov]
  • All patients who presented with stupor, (a) partial or total mutism or (b) absent or decreased motor responses (n 22), were compared with patients who also had classical catatonic signs such as negativism or waxy flexibility (n 43) over a one-year period[ncbi.nlm.nih.gov]
  • Other catatonic signs included rigidity, negativism, grimacing, posturing, and immobility; the dominant clinical picture was one of stupor. His BF score was 18. Ten hours later, mania spontaneously reemerged.[ncbi.nlm.nih.gov]
Akinesia
  • This patient, with a preexisting diagnosis of autism, posturing, nonverbal communication, and contracture of lower extremities, displaying mutism, akinesia, and an extreme level of rigidity, waxy flexibility, and posturing, was diagnosed as with catatonic[ncbi.nlm.nih.gov]
Myoclonic Jerking
  • .  Myoclonic jerking, - anoxic encephalopathy or metabolic comas, such as hepatic encephalopathy.  Rhythmic myoclonus- brainstem injury.  Tetany occurs with hypocalcemia.  Cerebellar fits of Hughlings Jackson”  result from intermittent tonsillar[slideshare.net]

Workup

Triphasic Waves
  • Her electroencephalogram (EEG) showed bilaterally synchronous runs of three-phase waves consistent with the triphasic waves typically seen in metabolic encephalopathy.[ncbi.nlm.nih.gov]
  • These include metabolic disturbances such as hepatic or renal dysfunction, which are often characterized by slowing of background rhythms and triphasic waves.[ncbi.nlm.nih.gov]
Periodic Lateralized Epileptiform Discharges
  • Several EEG patterns and their interpretation in suspected cases of NCSE such as periodic lateralized epileptiform discharges (PLEDs), bilateral independent periodic lateralized epileptiform discharges (BIPLEDs), generalized periodic epileptiform discharges[ncbi.nlm.nih.gov]
Burst Suppression
  • Hypoxia and drug intoxications can produce a number of abnormal EEG patterns such as burst suppression, alpha coma, and spindle coma. Structural lesions, either supra- or infratentorial, are reviewed.[ncbi.nlm.nih.gov]
PLED Bilaterally
  • Several EEG patterns and their interpretation in suspected cases of NCSE such as periodic lateralized epileptiform discharges (PLEDs), bilateral independent periodic lateralized epileptiform discharges (BIPLEDs), generalized periodic epileptiform discharges[ncbi.nlm.nih.gov]

Treatment

  • Follow-up outpatient treatment with olanzapine improved his social functions.[ncbi.nlm.nih.gov]
  • We describe a patient who entered a stuporous state after receiving benzodiazepine treatment for generalized tonic-clonic status epilepticus.[ncbi.nlm.nih.gov]
  • To describe the treatment and outcome of organic stupor associated with MRI evidence of cerebrovascular disease. A case series of three patients. An urban mental health of the elderly service in southeast London.[ncbi.nlm.nih.gov]
  • After his physical recovery, treatment with risperidone (0.5-2.0 mg, 5 weeks) was started. However, hypersedation occurred, and the risperidone was switched to aripiprazole, with dose increases up to 18 mg/day (5 months).[ncbi.nlm.nih.gov]
  • In this report, we describe a case of rapid onset of stupor and loss of consciousness, subsequent evaluation, and treatment of catatonia in an HIV-positive man.[ncbi.nlm.nih.gov]

Prognosis

  • The presence of EEG spindle activity after hypoxic or anoxic injury did not indicate a favorable prognosis, but the absence of spindles or EEG background reactivity was associated with a poor outcome.[ncbi.nlm.nih.gov]
  • It then describes the emergency treatment, both medical and surgical, of patients with specific disorders of consciousness and their prognosis.[books.google.de]
  • It also describes the emergency treatment, both medical and surgical, of patients with specific disorders of consciousness and their prognosis.[oxfordmedicine.com]
  • We review diagnosis and prognosis in disorders of consciousness, address ethical challenges arising in the care of these patients, and provide a guide to discussions with surrogate decision makers for the comatose or severely brain-injured patient.[accessmedicine.mhmedical.com]

Etiology

  • The onset of psychiatric symptoms, closely followed by neurological symptoms, without other possible somatic etiology suggests that HIV itself might precipitate psychosis. The patient was treated successfully with electroconvulsive therapy.[ncbi.nlm.nih.gov]
  • Evaluation revealed elevated serum LTG levels and no other etiology for encephalopathy. LTG was withheld, and the patient experienced a complete recovery in conjunction with reduced serum levels.[ncbi.nlm.nih.gov]
  • However, after intravenous administration of diazepam, the EEG abnormalities improved; indicating that her decreased consciousness was of epileptic etiology, consistent with spike-wave stupor.[ncbi.nlm.nih.gov]
  • The mechanism of coma in toxic, metabolic, and infectious etiologies and hypothermia is less well understood and to some extent is cause specific.[uptodate.com]
  • Practically all categories in the chapter could be designated 'not otherwise specified', 'unknown etiology' or 'transient'.[icd10data.com]

Pathophysiology

  • Although the manifold signs of ocular motor dysfunction may be confusing to most clinicians, many of the signs can be attributed to clear pathophysiological mechanisms.[ncbi.nlm.nih.gov]
  • We attempted to elucidate the pathophysiological mechanism of VPA-induced stupor and provide further polygraphic and backaveraging EEG documentation of negative myoclonus.[ncbi.nlm.nih.gov]
  • The book begins with a description of the physiology of consciousness and the pathophysiology of disorders of consciousness.[books.google.de]
  • It begins with a description of the physiology of consciousness and the pathophysiology of disorders of consciousness, followed by a description of the approach to a patient, and reviews the important structural and metabolic causes of coma are reviewed[oxfordmedicine.com]
  • "The 4th edition is every bit as wonderful as the preceding 3, only with much more information...It is a wonderful clinical guide with clear descriptions of pathophysiology and application of modern technology for diagnosis."-- Lewis P.[amazon.com]

Prevention

  • We used the vigilance promoting drug modafinil to prevent such attacks in a case presented with endozepine stupor.[ncbi.nlm.nih.gov]
  • The charcoal prevents the stomach from absorbing more of the substances.[merckmanuals.com]
  • During her years in hospitals, Abdulla was tube-fed and underwent physiotherapy to prevent her muscles deteriorating.[aawsat.com]
  • Notes Being drunk does not prevent the Nemesis hit men, Feast of Boris, or El Dia de Los Muertos Borrachos monsters from appearing. You can get eggs on Oyster Egg Day while drunk.[kol.coldfront.net]

Ask Question

5000 Characters left Format the text using: # Heading, **bold**, _italic_. HTML code is not allowed.
By publishing this question you agree to the TOS and Privacy policy.
• Use a precise title for your question.
• Ask a specific question and provide age, sex, symptoms, type and duration of treatment.
• Respect your own and other people's privacy, never post full names or contact information.
• Inappropriate questions will be deleted.
• In urgent cases contact a physician, visit a hospital or call an emergency service!