Presentation
This newly-published abstract reviews the clinical presentation of frontal-subcortical dementias, lists them, and suggests how they relate to cortical dementias. The classic “cortical dementia” is Alzheimer’s Disease. [brainsupportnetwork.org]
The loss of several subcortical afferents to prefrontal cortex may be responsible for the frontal cortical hypometabolism present in PSP. x [scite.ai]
Breaking away from prevailing views of dementia that rely heavily on the role of the cerebral cortex, the new perspective put forth here highlights white matter-cognition relationships, presenting an expanded view of dementia and its neurobiological origins [books.google.ae]
Abstract In this report, we present the cases of two 63-year-old women who developed high altitude cerebral edema complicated by the occurrence of permanent neuropsychiatric sequelae. [liebertpub.com]
OBJECTIVE The authors describe and quantify the neuropsychiatric symptoms present in a cohort of males with the fragile X mental… Expand Frontal-subcortical circuits form the principal network, which mediate motor activity and behavior in humans. [semanticscholar.org]
Entire Body System
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Fishing
If you like to fish or play cards, keep doing that for as long as you can. Know that there will be good and bad days. Find something to enjoy whenever possible. If you start feeling hopeless or depressed, talk to your doctor or a counselor. [betterhelp.com]
Respiratoric
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Pharyngitis
[…] intestine later lesion less limbs lower lung marked membrane method months movements muscles nature nerve normal observed occur onset opening operation organs origin ovarian ovary pain palate pancreas paralysis parasite pass patient peritoneum peritonitis pharyngitis [books.google.com.tr]
Musculoskeletal
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Muscle Spasm
When subcortical dementia syndrome symptoms affect an individual with Parkinson’s or Alzheimer’s, it is this cortico-basal ganglia-cortical loop that is disrupted enough to cause symptoms such as: Tremors and muscle spasms Memory difficulties Inability [caregiverrelief.com]
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Motor Restlessness
Problems with motor symptoms are common with subcortical dementia that presents extrapyramidal symptoms that can include continuous muscle contractions and spasms also known as dystonia, motor restlessness, rigidity, slowness of movement, and tremor amongst [readementia.com]
Psychiatrical
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Psychomotor Retardation
et al ( 1987 ) Bradyphrenia in Parkinson's disease and psychomotor retardation in depression. An experimental study. Brain, 100, 761 – 776. Saint-Cyr, J. A., Taylor, A. E. & Lang, A. [cambridge.org]
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Anhedonia
[…] to help recruit an expert. ( February 2018 ) Subcortical dementia Specialty Neurology Subcortical dementia is a type of dementia characterised by slowness of mental processing, forgetfulness, impaired cognition, apathy, depressive symptoms (such as anhedonia [en.wikipedia.org]
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Anger
That bit of information can come with a range of strong emotions that can include: anger, emotional numbness, relief, denial, resentment, fear, sadness, hopelessness, and isolation. Recognizing and accepting these feelings can help. [betterhelp.com]
Neurologic
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Cognitive Impairment
[…] with cognitive impairment. [ahajournals.org]
1 General anesthesia considerations in CADASIL disease. 38 30665799 2019 2 History of Subcortical Cognitive Impairment. 38 Filley CM 31220831 2019 3 Secondary dementia due to Lyme neuroborreliosis. 38 Kristoferitsch W...Fischer P 30046879 2018 4 Total [malacards.org]
Subcortical dementia is noted for a special type of cognitive impairment, characterised by marked psychosocial incompetence associated with minimal memory loss and, as a rule, absence of aphasia, apraxia, or agnosia. [go.gale.com]
Aberrant adenosine A2A receptor signaling contributes to neurodegeneration and cognitive impairments in a mouse model of synucleinopathy. Experimental Neurology, Vol. 283, Issue., p. 213. [cambridge.org]
Differential cognitive impairment in Alzheimer's disease and Huntington's disease. Annals of Neurology, 23, 555 - 561. Google Scholar Crossref Medline ISI Bruyn, G. W., Bots, G., & Dom, R. ( 1979 ). [journals.sagepub.com]
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Dystonia
Problems with motor symptoms are common with subcortical dementia that presents extrapyramidal symptoms that can include continuous muscle contractions and spasms also known as dystonia, motor restlessness, rigidity, slowness of movement, and tremor amongst [readementia.com]
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Extrapyramidal Symptoms
Problems with motor symptoms are common with subcortical dementia that presents extrapyramidal symptoms that can include continuous muscle contractions and spasms also known as dystonia, motor restlessness, rigidity, slowness of movement, and tremor amongst [readementia.com]
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Excitement
T2 and proton-density (PD) weighted MR images were acquired using 3-mm-thick slices (TE 30, 80 ms; TR 3000 ms, 0.5 excitations, field of view 20 20 cm, matrix 256 192). [ahajournals.org]
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Pyramidal Tract Signs
Parkinsonism with prominent gait disturbances in conjunction with pyramidal tract signs, dysarthria, pseudobulbar affect, and incontinence are frequent motor manifestations of VAD with small vessel disease. [karger.com]
Treatment
Based on detailed patient observations, extensive clinical research and an exhaustive literature review, this book discusses the novel concept of white matter dementia, offering hope for better understanding and treatment of dementing illness. [books.google.ae]
Attempting to control symptoms and keep patients as comfortable as possible is currently the best treatment method. [caregiverrelief.com]
Treatment: Although subcortical dementia is a progressive deterioration of the brain, a diagnosis must be made before treatment is given. The amount of damage this disease causes directly relates to the cause of the dementia. [medigoo.com]
Treatment and Management Treatments and management of dementia generally have focused most on Alzheimer's disease since it's the most common cause of dementia. [verywellhealth.com]
Disease Burden Correlates with Cognitive Performance, Cortical Atrophy, and Network Measures in a Memory Clinic Population. 38 Banerjee G...Werring DJ 29843234 2018 5 HIV-1-associated neurocognitive disorder: epidemiology, pathogenesis, diagnosis, and treatment [malacards.org]
Prognosis
Prognosis The prognosis of cortical and subcortical dementias varies significantly. Several different types of dementia fall into these categories, and progression is affected by a multitude of factors. [verywellhealth.com]
Prognosis The prognosis of cortical and subcortical dementia also significantly varies. Because different types of dementias fall under these two categories, multiple factors commonly affect prognosis. [readementia.com]
NPH Treatment and Prognosis Unlike other forms of dementia, there are some effective treatments for NPH. [kindlycare.com]
Catching vascular dementia early and preventing further damage makes for a better prognosis. [explainingmedicine.com]
SLIDESHOW Dementia, Alzheimer's Disease, and Aging Brains See Slideshow What is the prognosis for Binswanger's disease? Binswanger's disease is a progressive disease; there is no cure. [medicinenet.com]
Etiology
Recent reports that the… Expand Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is characterized by a… Expand Vascular dementia (VAD) is common, and small vessel disease is one of the most frequent etiologies [semanticscholar.org]
Article / Publication Details First-Page Preview Abstract Vascular dementia (VAD) is common, and small vessel disease is one of the most frequent etiologies of the disorder. [karger.com]
Most importantly, the underlying etiologies are those of well-recognized vascular risk factors, and this is, therefore, a form of cognitive impairment that is amenable to prevention as well as symptomatic relief. [medlink.com]
ETIOLOGY NEURO- DEGENERATIVE Alzheimer's Ds; Dementia with Lewy Bodies; Fronto- temporal dementia; Parkinson’s Ds VASCULAR Infarction; Hemodynamic insufficiency NEUROLOGICAL Multiple Sclerosis; Normal Pressure Hydrocephalus ENDOCRINE Hypothyroidism NUTRITIONAL [slideshare.net]
Epidemiology
P 30046879 2018 4 Total MRI Small Vessel Disease Burden Correlates with Cognitive Performance, Cortical Atrophy, and Network Measures in a Memory Clinic Population. 38 Banerjee G...Werring DJ 29843234 2018 5 HIV-1-associated neurocognitive disorder: epidemiology [malacards.org]
Epidemiological studies have shown that sVAD shares with cerebrovascular disease most of the common risk factors. The molecular basis of this pathology remains controversial. [dovepress.com]
Open Access Article 1 Department of Epidemiology. Fay W. [mdpi.com]
EPIDEMIOLOGY 5 to 8 % at age 65 to 70 15 to 20 % at age 75 to 80 up to 40 to 50 % over age 85 • Alzheimer's disease is most common dementia 50-75% • Dementia with Lewy bodies 15 to 35 % • Vascular dementia 5 – 20 % 5. [slideshare.net]
Epidemiology of early-onset dementia: a review of the literature. Clinical practice and epidemiology in mental health: CP & EMH 2013;9:88. Ye BS, Seo SW, Kim GH, et al. [researchsquare.com]
Pathophysiology
Parkinson’s disease: Pathophysiology. Lancet, 337, 1321–1324. Albert, M. L., Feldman, R. G., & Willis, A. L. (1974). The “subcortical dementia” of progressive supranuclear palsy. Journal of Neurology, Neurosurgery, and Psychiatry, 37, 121–130. [pubs.asha.org]
Neuropsychology, neuropsychiatry and pathophysiology. British Journal of Psychiatry, 149, 682 – 697. Cummings, J. L. ( 1995 ) Behavioural and psychiatric symptoms associated with Huntington's disease. [cambridge.org]
Biomarkers of AD pathophysiology involve cerebrospinal fluid (CSF) Aβ 1 42 plaque deposition, tau accumulation and neurodegeneration 13, 14, which are collectively referred to as ATN. [researchsquare.com]
Perceptual disturbances Delusions Perplexity Thought disorder Behavioural and other symptoms Agitation Irritability Labile affect Word-finding difficulties Temporal course Rapid onset Fluctuation over 24-hour period Reversal of sleep–wake cycle The pathophysiological [neupsykey.com]
Prevention
The best thing you can do if you don't have the disease already is to do what you can to prevent it. Prevention For people who don't have dementia right now, there may be some things you can do to prevent it. [betterhelp.com]
Alzheimer's disease, the author reconsiders brain-behavior relationships and expands the concept of dementia, discussing implications for diagnosis, treatment (medical, surgical, rehabilitative, and psychiatric) and therapeutic innovations aimed at prevention [books.google.ae]
Preventing Dementia Although research has yet to discover why Parkinson’s and Huntington’s disease is triggered in certain individuals, belief that a genetic component may exist to explain the origin of the disease is a theory popular among neurologists [caregiverrelief.com]
Thus, treatments aimed at preventing CVD may play a significant role in preventing the onset, or ameliorating the severity, of cognitive decline in older age. [ahajournals.org]
[…] die Deutsche Neuro-AIDS-Arbeitsgemeinschaft (DNAA) 25292163 2014 21 Dementia with Lewy bodies. 38 Mayo MC...Bordelon Y 24963677 2014 22 Advancements in understanding the mechanisms of symptomatic lacunar ischemic stroke: translation of knowledge to prevention [malacards.org]