Presentation
Clinical presentation, radiological, and pathological studies of this case of subependymoma are presented. The incidence of spinal subependymoma was also discussed in light of a literature review. [ncbi.nlm.nih.gov]
Entire Body System
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Coronary Atherosclerosis
Coronary atherosclerosis and mild cardiac hypertrophy were present as the only pathologic changes outside the central nervous system. The cause of death is discussed in light of earlier reports on brain tumours and sudden fatal incidents. [ncbi.nlm.nih.gov]
Gastrointestinal
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Overeating
Over half were entirely intraventricular, 6 extended into brain substance and 2 into subarachnoidal cisterns. Twelve were isodense, 15 showed diffuse but irregular enhancement, and 5 contained nodular calcification. [ncbi.nlm.nih.gov]
Highlights of this edition include over 6,800 images of remarkable quality, more color images, and new information using advanced techniques, including perfusion and diffusion MRI and functional MRI. [books.google.ro]
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Nausea
She had a 2-month history of progressive headache, neck stiffness and nausea. Computed tomography revealed hydrocephalus for which a ventriculoperitoneal shunt was inserted. [ncbi.nlm.nih.gov]
Eyes
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Eye Movements Abnormal
More recently, he developed progressive eye movement abnormalities. On examination, he had right partial cranial nerve (CN) VII and right CN VIII palsies, nystagmus, right-sided dysmetria, and hyperreflexia. [ajnr.org]
Musculoskeletal
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Low Back Pain
We report a case of a 61-year-old male who presented with a 3-year history of low back pain, associated with right lower limb progressive weakness and sensory numbness. [ncbi.nlm.nih.gov]
Urogenital
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Sexual Dysfunction
They often present clinically with pain and neurologic symptoms, including motor, sensory, urinary, and sexual dysfunction. [ncbi.nlm.nih.gov]
Two years later, with hormone replacement therapy (desmopressin, hydrocortisone, levothyroxine, testosterone undecanoate) there was no sexual dysfunction. [endocrine-abstracts.org]
The severe symptoms include fatigue, numbness, weakness and sexual dysfunction which was reported by all patients. [cern-foundation.org]
Neurologic
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Headache
She had a 2-month history of progressive headache, neck stiffness and nausea. Computed tomography revealed hydrocephalus for which a ventriculoperitoneal shunt was inserted. [ncbi.nlm.nih.gov]
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Long Tract Signs
Patients with intraspinal subependymomas initially presented with back pain and long-tract signs. The tumors were hyperintense on T2-weighted MR imaging, isointense on T1-weighted imaging, and noncontrast enhancing. [ncbi.nlm.nih.gov]
Results Patients with intraspinal subependymomas initially presented with back pain and long-tract signs. The tumors were hyperintense on T2-weighted MR imaging, isointense on T1-weighted imaging, and noncontrast enhancing. [doi.org]
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Altered Mental Status
The patient developed sudden onset of headache and altered mental status followed by complete resolution, likely due to intermittent hydrocephalus. [ncbi.nlm.nih.gov]
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Exertional Headache
@article{418947fe56b8469d8b74837da6b8bb5c, title "Subependymoma of septum pellucidum presenting with cough and exertional headache: A case report of spontaneous regression after incomplete surgical removal", author "Aldo Spallone and Massimiliano Visocchi [moh-it.pure.elsevier.com]
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Dysphasia
Note the absence of perilesional edema, and the lack of contrast enhancement Because the patient suffered progressive clinical decline, characterized by dysphasia and paresis of the lower extremities, we placed a ventriculostomy to control his malignant [surgicalneurologyint.com]
Workup
Conclusions: The case is an educative example about the necessity to keep possible intracranial lesions in mind when starting the workup of a patient presenting with erectile dysfunction. [endocrine-abstracts.org]
4th ventricle, symptoms are related to obstruction and subsequently increased intracranial pressure In spinal ependymomas, presentation is typically with sensory deficits (compared with astrocytomas, which tend to present with pain and motor symptoms) Workup [en.wikibooks.org]
[…] tumors are isointense or slightly hypointense to the surrounding spinal cord on T1-weighted images; most tumors are hyperintense to the spinal cord on T2-weighted images Other diagnostic modalities that may be helpful include the following: EEG See Workup [emedicine.medscape.com]
HLA Type
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HLA-DR2
She was positive for HLA-DR2. At autopsy there was a tumour dorsal to the fourth ventricle which involved the midbrain tectum and rostral pons. Histologic examination of the tumour confirmed it to be a subependymoma. [ncbi.nlm.nih.gov]
Treatment
Consequently, we explore the SEER database to evaluate prognostic and treatment factors associated with intracranial subependymoma. [ncbi.nlm.nih.gov]
The child may have had treatment to relieve signs or symptoms caused by the tumor. Subependymoma Treatment of newly diagnosed subependymoma (WHO ... 4 ... [familydiagnosis.com]
Prognosis
Although radical removal is considered the rational goal of treatment, larger experience is necessary to know both the rate of growth and prognosis of subependymomas when these tumors arise within the spinal cord. [ncbi.nlm.nih.gov]
Tumors, attached to the floor of the fourth ventricle carry the worst prognosis, because of the location. A mixed ependymomasubependymoma carries a worse prognosis than a pure subependymoma. [ependymomas.com]
Etiology
This case lends support to the notion that some subependymomas are reactive in etiology. [ncbi.nlm.nih.gov]
While etiological, pathological and therapeutic characteristics have… CONTINUE READING [semanticscholar.org]
Subependymomas have been described with features identical to this case, however, since these commonly present as non-enhancing intraventricular lesions [5,7], it was felt to be a less likely etiology. [sciforschenonline.org]
PMID 18579016 What is the etiology of human brain tumors? A report on the first Lebow conference. Brem S, Rozental JM, Moskal JR. Cancer. 1995 Aug 15;76(4):709-13. [atlasgeneticsoncology.org]
Epidemiology
Epidemiology Subependymomas are often asymptomatic tumors discovered on autopsy. Autopsy series have estimated that subependymomas account for 8.3% of all ependymal tumors. [prod.wiki.cns.org]
Accessed on January 12, 2016 6.0 6.1 Epidemiology of subependymoma. Dr Bruno Di Muzio and A.Prof Frank Gaillard et al. Radiopaedia 2016. . Accessed on January 12, 2016 7.0 7.1 Clinical presentation of subependymoma. [wikidoc.org]
/ general Benign slowly growing neoplasm typically attached to a ventricular wall Cell of origin unknown but resembles subependymal tissue Slow growing; 50% have symptoms (associated with larger size or specific locations, J Neurosurg 1978;49:689 ) Epidemiology [pathologyoutlines.com]
Epidemiology Descriptive epidemiology largely depends on population-based cancer registries, which record cases according to the International Classification of Diseases for Oncology (ICD-O). [atlasgeneticsoncology.org]
The largest case series published to date describe an incidence of 0.4-0.7%, which is larger in middle-aged or senior males, with a mean age of presentation between 48.5 and 53.6 years.[ 3 12 16 19 ] Epidemiologically, our patient coincides with the international [surgicalneurologyint.com]
Pathophysiology
It brings together the pathophysiology of disease with detailed clinical guidance on diagnosis and management for the full range of childhood cancers, including aspects important in optimal supportive care. [books.google.com]
Subependymal astrocytoma; Subependymal astrocytomas Overview Subependymoma is a type of brain tumor; specifically, it is a rare form of ependymal tumors. [1] Subependymoma is a benign ( WHO grade I ) tumor, which is slow growing and non-invasive. [2] Pathophysiology [wikidoc.org]
In adults and adolescents, 75% of ependymomas arise within the spinal canal, with a significant minority occurring intracranially in the supratentorial compartment. [12] Pathophysiology Ependymomas are traditionally thought to arise from oncogenetic events [emedicine.medscape.com]
Prevention
Surgical extirpation is one of the treatment options to establish the correct diagnosis and to prevent symptoms. [ncbi.nlm.nih.gov]
Prevention - Subependymoma Not supplied. Diagnosis - Subependymoma Not supplied. Prognosis - Subependymoma Subependymal tumors are slow growing tumors. Surgical resection alone often offers a cure. [checkorphan.org]