The percent of dose excreted in urine over a 12-hour period following the intravenous administration of the first dose of 1200 mg of sulfamethoxazole and 240 mg of trimethoprim on day 1 ranged from 7% to 12.7% as free sulfamethoxazole and 17% to 42.4% [globalrph.com]

Intravenous Administration Rapid or direct IV injection must be avoided. Dilute 5 ml of the concentrate for injection in 125 ml of D5W. For fluid-restricted patients, 75 ml of D5W may be used. [pdr.net]

The hypoxemia and ground-glass opacity increased on hospital day 3, and the administration of adjunctive steroid therapy resulted in an improvement in the patient's condition. [ncbi.nlm.nih.gov]

Tell your doctor right away if you have any of the following symptoms while using this medicine: confusion, weakness, muscle twitching, an irregular heartbeat, numbness or tingling in the hands, feet, or lips, or trouble breathing. [goodrx.com]

Transient alopecia was observed in one patient during therapy. We conclude that prophylactic treatment with sulfamethoxazole-trimethoprim is beneficial in patients with chronic granulomatous disease. [ncbi.nlm.nih.gov]

Ambramowicz Med Drugs that may cause psychiatric symptoms. Med Lett Drugs Ther. 2000;4459- 62Google Scholar 31. McCue JDZandt JR Acute psychoses associated with the use of ciprofloxacin and trimethoprim-sulfamethoxazole. [jamanetwork.com]

The clinical results were as follows; mild improvements of hyperreflexia of knee jerks and of rigospasticity of the legs during S-T treatment period. In addition, S-T significantly reduced the times of 8 motor activities on the timed tests. [ncbi.nlm.nih.gov]

Both patients presented a platelet count below 5,000/microL, extensive purpura, and significant vaginal bleeding. [ncbi.nlm.nih.gov]

Patients with at least one of the two PCP risk factors (interstitial pulmonary fibrosis and lymphopenia), were administered either one (11 patients) or two (26 patients) ST tablets/day. [ncbi.nlm.nih.gov]

No significant influence of initial neutrophil count on response rate was noted, although patients in whom the neutrophil count increased during therapy had a higher response rate (84%) than patients in whom the neutrophil count decreased or remained [ncbi.nlm.nih.gov]