A 16-year-old African-American female presented with a surgical site infection 8 weeks after a motor vehicle accident with multiple traumas. [ncbi.nlm.nih.gov]

• Streptococcal Infection

  […] reported; hyperkalemia and hyponatremia also appear to be increased Severe cases (including fatalities) of immune-mediated thrombocytopenia reported; monitor patients for hematologic toxicity Sulfonamides should not be used to treat group A beta-hemolytic streptococcal [reference.medscape.com]

  Streptococcal infection (group A β-hemolytic)—Sulfonamides should not be used in patients with this condition. [goodrx.com]

  The sulfonamides should not be used for the treatment of group A beta-hemolytic streptococcal infections. In an established infection, they will not eradicate the streptococcus and, therefore, will not prevent sequelae such as rheumatic fever. [globalrph.com]

  There is, however, a lack of good controlled studies concerning the efficacy of TMP-SMZ in the management of group A streptococcal infections. [academic.oup.com]

  Antimicrobial resistance, viral infection Sulfamethoxazole; trimethoprim will not effectively treat an established group A beta-hemolytic streptococcal infection; therefore, its use in patients with such infections should be avoided. [pdr.net]

• Recurrent Urinary Tract Infection

  An intravenous form of the antimicrobial combination has recently been approved for the treatment of acute, symptomatic, bacterial pyelonephritis, recurrent urinary tract infections, shigellosis, and Pneumocystis carinii pneumonia. [ncbi.nlm.nih.gov]

  tract infections and shigellosis. [glowm.com]

  Pediatric patients (n = 564, median age = 14 months) with recurrent urinary tract infections (UTIs) were included; there was a 7% reduction in the absolute risk of symptomatic UTIs in predisposed children. [pdr.net]

• Intravenous Administration

  Administration The solution should be given by intravenous infusion over a period of 60 to 90 minutes. Rapid infusion or bolus injection must be avoided. Sulfamethoxazole and trimethoprim injection should not be given intramuscularly. [globalrph.com]

  Injectable Administration Visually inspect parenteral products for particulate matter and discoloration prior to administration whenever solution and container permit. Intravenous Administration Rapid or direct IV injection must be avoided. [pdr.net]

• Pneumonia

  Pneumocystis/etiology Pneumonia, Pneumocystis/immunology Pneumonia, Pneumocystis/microbiology Pneumonia, Pneumocystis/prevention & control* Pre-Exposure Prophylaxis* Retrospective Studies Sputum/microbiology Trimethoprim, Sulfamethoxazole Drug Combination [ncbi.nlm.nih.gov]

  This medicine is also used to prevent or treat Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP), a very serious kind of pneumonia. [mayoclinic.org]

• Suggestibility

  Sulfamethoxazole-trimethoprim may be an alternative or adjunctive treatment for Wegener's granulomatosis, as suggested by our experience with six patients. [ncbi.nlm.nih.gov]

• Staphylococcus Aureus

  Introduction Trimethoprim-sulfamethoxazole is an old antibiotic active against Staphylococcus aureus. [bmj.com]

  Role of folate antagonists in the treatment of methicillin-resistant Staphylococcus aureus infection. Clin Infect Dis. 2008;46(4):584-593. [PubMed] Close S, McBurney C, Garvin C, Chen D, Martin S. [aliem.com]

  A 26-year-old pregnant woman who was an intravenous drug user (IDU) was admitted to our hospital for the treatment of tricuspid valve infective endocarditis (IE) and lung abscesses due to methicillin-resistant Staphylococcus aureus (MRSA). [ncbi.nlm.nih.gov]

Diagnosis and treatment were carried out by nurses, without medical supervision. [ncbi.nlm.nih.gov]

TMP/SMX was identified as the likely etiology of pancreatitis by the medical team. Evaluation with the Naranjo algorithm indicated a "possible" adverse drug reaction. [ncbi.nlm.nih.gov]

In those cases in which an etiologic agent has been identified, viruses, in particular coxsackie B viruses, have been most frequently implicated ( 4 ). [wwwnc.cdc.gov]

Department of Rheumatology, JA Toride Medical Center, 2-1-1 Hongo, Toride, Ibaraki, 302-0022, Japan. 20 Clinical Research Center, Medical Hospital of Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo, Tokyo, 113-8549, Japan. 21 Division of Epidemiology [ncbi.nlm.nih.gov]

"Tularemia: Epidemiology, Diagnosis, and Treatment" (PDF). Pediatric Annals. 42 (7): 288–292. doi:10.3928/00904481-20130619-13. PMID 23805970. [en.wikipedia.org]

The study was performed in compliance with the ethical guidelines for epidemiological research in Japan and the Helsinki Declaration (revised in 2008). [arthritis-research.biomedcentral.com]

Molecular epidemiology and antimicrobial susceptibility profiles of methicillin-resistant Staphylococcus aureus blood culture isolates: results of the Quebec Provincial Surveillance Programme. [bmj.com]

Therefore, the prophylactic administration of sulfamethoxazole-trimethoprim has potential to be effective in preventing P. pneumonia as well as eliminating airway colonization with P. jirovecii. [ncbi.nlm.nih.gov]

The Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents include recommendations on uses of sulfamethoxazole/trimethoprim in people with HIV. [aidsinfo.nih.gov]

chancroid, and prevention of toxoplasma encephalitis in patients with AIDS. [medicinenet.com]

This is a combination antibiotic used to prevent or treat a type of lung infection called PCP or PJP which is caused by a fungus. This type of infection is more common in patients who have a suppressed immune system. [transplant.bc.ca]

Antibiotic prophylaxis to prevent spontaneous bacterial peritonitis in people with liver cirrhosis: a network meta-analysis. [pubmed.ncbi.nlm.nih.gov]