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Sulfamethoxazole-Trimethoprim
Centran

Presentation

A 16-year-old African-American female presented with a surgical site infection 8 weeks after a motor vehicle accident with multiple traumas. [ncbi.nlm.nih.gov]

Entire Body System

  • Intravenous Administration

    Administration The solution should be given by intravenous infusion over a period of 60 to 90 minutes. Rapid infusion or bolus injection must be avoided. Sulfamethoxazole and trimethoprim injection should not be given intramuscularly. [globalrph.com]

    Injectable Administration Visually inspect parenteral products for particulate matter and discoloration prior to administration whenever solution and container permit. Intravenous Administration Rapid or direct IV injection must be avoided. [pdr.net]

Psychiatrical

  • Psychiatric Symptoms

    Ambramowicz Med Drugs that may cause psychiatric symptoms. Med Lett Drugs Ther. 2000;4459- 62Google Scholar 31. McCue JDZandt JR Acute psychoses associated with the use of ciprofloxacin and trimethoprim-sulfamethoxazole. [jamanetwork.com]

Treatment

Diagnosis and treatment were carried out by nurses, without medical supervision. [ncbi.nlm.nih.gov]

Etiology

TMP/SMX was identified as the likely etiology of pancreatitis by the medical team. Evaluation with the Naranjo algorithm indicated a "possible" adverse drug reaction. [ncbi.nlm.nih.gov]

In those cases in which an etiologic agent has been identified, viruses, in particular coxsackie B viruses, have been most frequently implicated ( 4 ). [wwwnc.cdc.gov]

Epidemiology

Department of Rheumatology, JA Toride Medical Center, 2-1-1 Hongo, Toride, Ibaraki, 302-0022, Japan. 20 Clinical Research Center, Medical Hospital of Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo, Tokyo, 113-8549, Japan. 21 Division of Epidemiology [ncbi.nlm.nih.gov]

"Tularemia: Epidemiology, Diagnosis, and Treatment" (PDF). Pediatric Annals. 42 (7): 288–292. doi:10.3928/00904481-20130619-13. PMID 23805970. [en.wikipedia.org]

The study was performed in compliance with the ethical guidelines for epidemiological research in Japan and the Helsinki Declaration (revised in 2008). [arthritis-research.biomedcentral.com]

Molecular epidemiology and antimicrobial susceptibility profiles of methicillin-resistant Staphylococcus aureus blood culture isolates: results of the Quebec Provincial Surveillance Programme. [bmj.com]

Prevention

chancroid, and prevention of toxoplasma encephalitis in patients with AIDS. [medicinenet.com]

Therefore, the prophylactic administration of sulfamethoxazole-trimethoprim has potential to be effective in preventing P. pneumonia as well as eliminating airway colonization with P. jirovecii. [ncbi.nlm.nih.gov]

The Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents include recommendations on uses of sulfamethoxazole/trimethoprim in people with HIV. [aidsinfo.nih.gov]

Antibiotic prophylaxis to prevent spontaneous bacterial peritonitis in people with liver cirrhosis: a network meta-analysis. [pubmed.ncbi.nlm.nih.gov]

This is a combination antibiotic used to prevent or treat a type of lung infection called PCP or PJP which is caused by a fungus. This type of infection is more common in patients who have a suppressed immune system. [transplant.bc.ca]

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