In addition, there may be one to two hours of chills, headache, nausea and malaise (a general sick feeling). In rare cases, PMLE may erupt as red plaques (flat, raised areas), small fluid-filled blisters or tiny areas of bleeding under the skin. [drugs.com]

Knee radiographic osteoarthritis (OA) and knee pain were also assessed. RESULTS: The mean 25(OH)D serum level was 52.8 nmoles/liter at baseline (range 13-119 nmoles/liter). [ncbi.nlm.nih.gov]

These associations were not significantly different in analyses stratified by gender, the presence of radiographic OA, or the presence of knee pain. [hopkinsarthritis.org]

Follow-up of the 2 adult patients showed reduced glomerular filtration rate and extrarenal manifestations, including calcic corneal deposits and osteoporosis. [ncbi.nlm.nih.gov]

CONCLUSIONS: The results support the hypothesis that chronic sun exposure is a risk factor of hearing impairment. [ncbi.nlm.nih.gov]

Facial wrinkle length and area of hyperpigmentation, which are considered to be associated with exposure to sun, were measured using imaging with computer-based image analysis. [ncbi.nlm.nih.gov]

And it all adds up over time to cause skin aging, fine lines, wrinkles, sun spots, elastosis (the degradation of the elastic tissue of the skin), the breakdown of collagen, hyperpigmentation, and other more serious conditions including skin cancer. [sunsaferx.com]

Serotonin and melatonin have also been implicated in many mental and cognitive disorders, such as Alzheimer's disease, Parkinson's disease, and sleep disorders [ 25, 29 ]. Light has been shown to also affect brain blood flow. [ncbi.nlm.nih.gov]

Uric acid increased by two-fold, which may be the adaptive response against photo-oxidative stress because uric acid is a good scavenger of singlet oxygen and oxygen radicals. [ncbi.nlm.nih.gov]

METHODS: This is a case-control study of 292 patients with IBD [132 with Crohn's disease (CD) and 160 with ulcerative colitis (UC)], 80 diseased and 540 healthy controls, conducted via a validated questionnaire to quantify sunlight exposure. [ncbi.nlm.nih.gov]