Presentation
The patient developed dry eyes after a month of first presentation. [ijo.in]
Case presentation A 28-year-old female patient presented to AIC Kijabe Hospital (KH) with a large, ulcerated mass on her left thigh which had been present for the previous 6 months. [link.springer.com]
In Table 1 we present an extensive differential diagnosis of granulomatous necrotizing and suppurative lymphadenitis [ 4, 5, 7 ]. [jmedicalcasereports.biomedcentral.com]
Present as persistent drainage, often with fecal material! May persist as a Polyp at the umbilicus = Umbilical Polyp Present as a Very Red mass within the umbilicus. Can contain gastric or intestinal tissue. Do not resolve with silver nitrate. [pedemmorsels.com]
Patients may present with widespread cutaneous ulcers. [ijdpdd.com]
Entire Body System
- Whipple Disease
Whipple’s disease, which was a serious diagnostic consideration, was thoroughly investigated and excluded. [jmedicalcasereports.biomedcentral.com]
Respiratoric
- Maxillary Sinus Pain
Case Report A 27-year-old man complained of 2-month history of nasal stuffiness, epistaxis and maxillary sinus pain. One month later, he developed painful swellings over the outer part of both eyes. [ijo.in]
Cardiovascular
- Vascular Disease
Alani, MD Klaus Busam, MD New York, New York J Am Acad Dermatol 2001;45:S225-6 Abstract quote Silicone compounds have recently been a source of controversy with regard to their potential role in the genesis of collagen vascular diseases. [thedoctorsdoctor.com]
Eyes
- Eye Swelling
He presented to us after another month with recurrence of eye swelling along with new development of dry cough. [ijo.in]
- Diplopia
There was no dry mouth, diplopia or ophthalmoplegia. Antinuclear, anti Ro and anti La antibodies were negative. There was complete regression of lung cavities with the above treatment after 3 months. [ijo.in]
Face, Head & Neck
- Sinus Pain
Case Report A 27-year-old man complained of 2-month history of nasal stuffiness, epistaxis and maxillary sinus pain. One month later, he developed painful swellings over the outer part of both eyes. [ijo.in]
Urogenital
Workup
Adequate clinical data and workup in combination with pathological resources can help in elucidation of specific etiology and good clinicopathologic correlation. [e-ijd.org]
Fine-needle aspiration (FNA) cytology is the first step in the workup for cervical lymphadenopathy; however, little has been published regarding the cytomorphological features of tularemia lymphadenitis. [karger.com]
Urine
- Albuminuria
Urine examination revealed active sediments [white blood cells (WBC) 20-25/high power field (HPF), red blood cells (RBC) 6-8/HPF], but no albuminuria. [ijo.in]
Serum
- Lymphopenia
A peripheral blood immunophenotypic analysis revealed lymphopenia due to simultaneous decrease of B-, T- and NK-cells. Serum beta-2-microglobulin levels were within normal limits. [jmedicalcasereports.biomedcentral.com]
Microbiology
- Listeria Monocytogenes
Induction of IDO by DCs is a cell-autonomous response to Listeria monocytogenes infection and was also observed in other granulomatous infections with intracellular bacteria, such as Bartonella henselae. [jci.org]
- Tropheryma Whipplei
Small bowel (jejunal and ileal) and colonic biopsies presented findings of non-specific inflammatory reaction, the architecture of intestinal villi was preserved and mucosal periodic acid-Schiff stain for detection of Tropheryma whipplei was negative. [jmedicalcasereports.biomedcentral.com]
Treatment
Topical treatments were allowed. [jamanetwork.com]
Treatment can begin with topical or systemic antibiotics, or both. [aafp.org]
New sections on treatment that highlight recent treatment trials and guidelines. Clinical descriptions updated. Brand new illustrations incorporated throughout. 14,000 new references. [books.google.com]
At present, definitive treatment guidelines for the management of HS are lacking due to the paucity of evidence based data and the unpredictable nature of the response to treatment. [imj.ie]
Such effects may occur, if the treatment of the tooth granuloma was not held in the initial stage of the disease, and gum tissue sprouted deep purulent sac. [noillen.bitballoon.com]
Prognosis
A distinct type of cutaneous B-cell lymphoma with an intermediate prognosis. Dutch Cutaneous Lymphoma Working Group. Arch Dermatol 1996; 132:1304-1308. Pagina 267 - Fletcher V, Sagebiel RW. [books.google.it]
Systemic disease, e.g. chronic granulomatous disease, Crohn's disease, sarcoidosis, systemic lupus erythematosus, IgG4 disease and other connective tissue disorders Idiopathic: 10 - 15% of all hepatic granulomas; a diagnosis of exclusion; excellent prognosis [pathologyoutlines.com]
Intratemporal complications include: Petrositis Facial paralysis [ 17 ] Labyrinthitis Intracranial complications include: Lateral sinus thrombophlebitis Meningitis Intracranial abscess Sequelae include: Hearing loss Tympanosclerosis Prognosis [ 2 ] Prognosis [patient.info]
The prognosis is excellent for patients with eosinophilic granuloma. Hand-Schüller-Christian disease This chronic, disseminated form of histocytosis X also occurs in children and young adults. [emedicine.medscape.com]
Etiology
Non-infectious etiologies require a thorough clinicopathologic review to narrow the scope of the pathogenesis which include: foreign body reaction, autoimmune, neoplastic, and drug related etiologies. [mayoclinic.pure.elsevier.com]
Suppurative stellate granuloma of undetermined etiology [granuloma.homestead.com]
Infectious etiologies, especially fungal and mycobacterial, should be excluded with special stains in any granulomatous process without obvious etiology. Examination under polarized light is required to exclude birefringent foreign material. [clinicalgate.com]
The differential diagnosis of granulomatous dermal inflammation is wide and is classified both by etiology and pattern of infiltrate. [link.springer.com]
It has been previously classified on the basis of pathophysiology, etiology, immunology, and morphology. [2] In the present study, granulomatous dermatitis was classified using a combination of etiology and morphology of granuloma. [e-ijd.org]
Epidemiology
[…] prevalence of periapical periodontitis is generally reported to vary according to age group, e.g. 33% in those aged 20–30, 40% in 30- to 40-year-olds, 48% in 40- to 50-year-olds, 57% in 50- to 60-year-olds and 62% in those over the age of 60. [3] Most epidemiologic [en.wikipedia.org]
Epidemiology Frequency To the authors' knowledge, no specific data on the incidence and prevalence of Majocchi granuloma exist. [emedicine.medscape.com]
Epidemiology Mean age for presentation is 6-7 years. Thereafter, there is a decrease in incidence with age [ 7 ]. They represent 0.5% of skin nodules in children [ 8 ]. [patient.info]
Harris MN, Desai R, Chuang TY, Hood AF, Mirowski GW: Lobular capillary hemangiomas: An epidemiologic report, with emphasis on cutaneous lesions. J Am Acad Dermat. 2000, 42 (6): 1012-1016. 10.1016/S0190-9622(00)90295-0. CrossRef Google Scholar 9. [link.springer.com]
Pathophysiology
Pathophysiology The pathophysiology of the fungal infection and defense mechanisms against superficial dermatomycosis has been studied. [6] Two series of experimental infections of T mentagrophytes were made on the forearm of a male volunteer with topical [emedicine.medscape.com]
Defect in integrin b 2 chain (shared by LFA-1 and Mac-1): CD18 Leukocyte Adhesion Deficiency Type II Clinical: Impaired leukocyte adhesion and recurrent bacterial infections (milder than LAD1) Pathophysiology: Absence of sialyl-Lewis X, ligand for E-selectin [pathologyexpert.com]
However as a significant proportion will still relapse, a better understanding of the underlying pathophysiology is essential to enable new therapeutic agents to be sought. [imj.ie]
It has been previously classified on the basis of pathophysiology, etiology, immunology, and morphology. [2] In the present study, granulomatous dermatitis was classified using a combination of etiology and morphology of granuloma. [e-ijd.org]
Prevention
Prevention and treatment of dental granuloma Depending on the size of the inflamed site, the surrounding tissue condition and the presence of complications, granuloma tooth treated by various methods: Conservative. [noillen.bitballoon.com]
There dentists will cut the gum and remove pus and install drainage to prevent formation of pus in the wound. Drainage is installed for 3 days. Anti-inflammatory medicamental therapy is also necessary. [dent-wiki.com]
Long-term outcomes (eg, healing of tympanic perforation, recurrence prevention and hearing improvement) need further study. [patient.info]
Complete surgical excision remains the treatment of choice to prevent recurrence. Increased public awareness is needed for the prevention of this physically and psychologically debilitating problem. [thedoctorsdoctor.com]
However, several treatment options are available, including preventive, medical, surgical, and psychological strategies ( Table 4 ). [aafp.org]