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Suprasellar Tumor

Cns Suprasellar Tumor


Presentation

  • This unusual presentation is discussed and plausible hypotheses are given.[ncbi.nlm.nih.gov]
  • METHODS: We present a case of a 10-year-old girl treated with therapeutic anticoagulation for previous cardiac valvular replacement, who presented with rapidly growing giant ( 4 cm) suprasellar germinoma.[ncbi.nlm.nih.gov]
  • Abstract A case report of ectopic pituitary gland in the suprasellar region of a normal 39-year-old woman with persistent headaches is presented.[ncbi.nlm.nih.gov]
  • This review outlines both common presenting features and differentiating aspects of these lesions. It also includes classic radiographic presentations and treatment considerations for each lesion. The Author(s) 2015.[ncbi.nlm.nih.gov]
  • We report the unusual presentation of a TRb in a 12-month-old boy with extensive bilateral Rb, a voluminous suprasellar tumor, pineal cyst, and leptomeningeal disease. The special features of this "quadrilateral" Rb are discussed.[ncbi.nlm.nih.gov]
Anosmia
  • Anosmia after anterior communicating artery aneurysm surgery: Comparison between the anterior interhemispheric and basal interhemispheric approaches. Neurosurgery 1996;38:325-8. [ PUBMED ] 4. Suzuki J, Katakura R, Mori T.[neurologyindia.com]
Diplopia
  • Within months of surgery, the patient’s diplopia and movement of her right eye improved. She had no other neurologic complaints.[barrowneuro.org]
  • Visual symptoms and signs include vision loss, diplopia, and multiple cranial nerve palsies secondary to rapid expansion of the tumor into the adjacent cavernous sinuses, with cranial nerve III the most commonly affected.[webeye.ophth.uiowa.edu]
  • By Luis Moreno Sánchez, MD, Frankie Viñals, MD, Enrique Mendoza, MD, Nathalie González Cazaño, MD, and Mario Ruiz MD CASE SUMMARY A 72-year-old woman with a one-month history of blurred vision, diplopia, left ptosis, dizziness and limited walking ability[appliedradiationoncology.com]
  • In some cases, a JPA may also be associated with seizures, vision problems such as blurred vision or double vision (diplopia), gradual changes in behavior or mood, and weakness of the arms and legs resulting in coordination difficulties.[rarediseases.org]
Progressive Visual Loss
  • Abstract A 37-year-old white woman presented with progressive visual loss in the right eye. The diagnostic evaluation suggested a tumor in the suprasellar area. At operation an isolated melanoma was found just superior to the sella turcica.[ncbi.nlm.nih.gov]
Oligomenorrhea
  • Four had oligomenorrhea with or without galactorrhea, one had amenorrhea with galactorrhea, and two complained of infertility.[ncbi.nlm.nih.gov]
Headache
  • Abstract A case report of ectopic pituitary gland in the suprasellar region of a normal 39-year-old woman with persistent headaches is presented.[ncbi.nlm.nih.gov]
  • In 1942, when she was 47 years old, she displayed the first symptoms of a suprasellar brain tumor: headache and hemianopsia.[ncbi.nlm.nih.gov]
  • Clinical presentation: A 55-years-old man with a history of persistent headache in the right frontal area for a period of 10 years prior to the admission as well as visual disturbances and decreased libido for 1 year period prior to the admission.[endocrine-abstracts.org]
  • The next frequent symptoms were headache and generalized lethargy. Diabetes insipidus was a presenting symptom in 4 cases and hydrocephalus was noted in 4 cases preoperatively.[jkns.or.kr]
Bitemporal Hemianopsia
  • An examination of her visual fields revealed bitemporal hemianopsia. Her corrected visual acuity with eye glasses was insufficient.[semanticscholar.org]
  • Physical examinations were normal except bitemporal hemianopsia revealed by ophthalmic examination. Preoperative neuroendocrine examinations showed a mild hyperprolactinemia of 72.3ng/ml (normal range, 2.8 ng/ml-29.2 ng/ml).[path.upmc.edu]
  • In four of the five known cases, bitemporal hemianopsia was the primary complaint (Table 1). Our patient’s only symptom was diplopia. Other symptoms reported to mimic pituitary adenomas are acromegaly, amenorrhea, and hypopituitarism (Table 1).[barrowneuro.org]

Workup

  • It is crucial to have a multidisciplinary team approach with baseline and follow up endocrine workup.[abstracts.eurospe.org]
  • It is important to note that while a sellar mass may present with bitemporal hemianopia, the combination of findings described above describing a junctional scotoma also localizes to the sellar area, and additional workup is indicated.[webeye.ophth.uiowa.edu]

Treatment

  • Combination treatment with metformin and pioglitazone was markedly effective in improving glycemic control. Additionally, metformin treatment showed marked anorectic effects on the hyperphagia.[ncbi.nlm.nih.gov]
  • He responded to treatment with corticosteroid and cyclophosphamide. The intracranial lesions seemed to be rare, but important manifestations of the systemic disease, and were clearly visualized by magnetic resonance imaging.[ncbi.nlm.nih.gov]
  • To round out the clinician's understanding of the illness, a patient describes the experience of diagnosis, treatment, and follow-up.[books.google.ro]
  • Make the best clinical decisions with an enhanced emphasis on evidence-based practice and expert opinions on treatment strategies. Zero in on the most relevant and useful references with the aid of a more focused, concise bibliography.[books.google.ro]
  • It also includes classic radiographic presentations and treatment considerations for each lesion. The Author(s) 2015.[ncbi.nlm.nih.gov]

Prognosis

  • Although rare, pure suprasellar germinomas carry worse prognosis than other locations.[ncbi.nlm.nih.gov]
  • It addresses diagnosis, pathophysiology, management and prognosis and is written in a clear, concise style for quick, easy reference in the clinic.[books.google.es]
  • Treatment and prognosis In general, a biopsy is required as treatment and prognosis will vary with histology (whereas it is independent of location).[radiopaedia.org]
  • The role of liver biopsy in fatty liver disease is contentious, not least because liver biopsy carries a finite risk of death ( 6 ) and the prognosis of NAFLD acquired in childhood is not yet known.[journals.lww.com]

Etiology

  • In 183 short chapters, the book provides the essentials clinicians need on symptoms/signs, diagnostic tests, and neurologic disorders of all etiologies. For this edition, Timothy A.[books.google.es]
  • Six major sections cover all topics related to epidemiology and etiology, molecular biology, clinical features and supportive care, imaging, neuroanatomy and neurosurgery, medical oncology and targeted therapies, and radiation oncology for adult and pediatric[books.google.ro]
  • […] signs; (3) endocrine disturbances are highly frequent before surgery, while surgical intervention had little effect in increasing endocrine morbidity; (4) NEC, even though producing less endocrine dysfunctions than other tumor types, are an important etiology[karger.com]
  • The etiology of fatty liver is poorly understood but is most commonly encountered in individuals with type 2 diabetes, truncal obesity and hyperlipidemia. Many of these patients demonstrate resistance to insulin ( 5 ).[journals.lww.com]

Epidemiology

  • Six major sections cover all topics related to epidemiology and etiology, molecular biology, clinical features and supportive care, imaging, neuroanatomy and neurosurgery, medical oncology and targeted therapies, and radiation oncology for adult and pediatric[books.google.ro]
  • Epidemiology As a general rule, brain tumors increase in frequency with age, with individual exceptions (e.g. pilocytic astrocytoma , the vast majority of which are found in young patients), and a number of uncommon tumors found in infancy (see brain[radiopaedia.org]
  • Jun 23rd, 2018 - The association between increasing body mass index (BMI; calculated as weight in kilograms divided by height in meters squared) and risk of breast cancer is unique in cancer epidemiology in that a crossover effect exists, with risk reduction[allmedx.com]
  • The epidemiology and long-term prognosis of fatty liver disease in children is not known. Hepatic steatosis occurs in many chronic liver diseases, some of which are amenable to treatment, such as Wilson’s disease and inherited metabolic diseases.[journals.lww.com]
Sex distribution
Age distribution

Pathophysiology

  • It addresses diagnosis, pathophysiology, management and prognosis and is written in a clear, concise style for quick, easy reference in the clinic.[books.google.es]

Prevention

  • Extreme caution was taken to avoid spillage of tumor cyst fluid into subarachnoid spaces, in order to prevent chemical meningitis.[neurologyindia.com]
  • In an effort to prevent further weight gain, a low-fat diet was introduced, but compliance was poor because of hyperphagia.[journals.lww.com]
  • Hospital for Sick Children Health A-Z Search a complete list of child health articles expand_more View All Drug A-Z Search a list of articles about medications expand_more View All Learning Hubs Browse a complete list of content groups Healthy Living & Prevention[aboutkidshealth.ca]
  • How can this disease be prevented? At present, there are no known preventive strategies for these cancers. Copyright 2017, 2013 Decision Support in Medicine, LLC. All rights reserved.[cancertherapyadvisor.com]

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