One finding in our study is that the bifocal location of tumors affects the prognosis more strongly than seeding at presentation itself. In fact, seeding at presentation was not a significant prognostic variable. [thejns.org]

Clinical presentation varies with the site of origin, but most patients present with headache, neck pain, gait disturbance, and vomiting. [ajronline.org]

This review outlines both common presenting features and differentiating aspects of these lesions. It also includes classic radiographic presentations and treatment considerations for each lesion. [pubmed.ncbi.nlm.nih.gov]

This unusual presentation is discussed and plausible hypotheses are given. [ncbi.nlm.nih.gov]

• Hyposmia

  Neurological complaints, such as mild mental or motor dysfunction, vertigo, epileptic attack, hyposmia, were present in a much lower degree (from 2.3 to 9.3% of patients) in addition to oculomotor paresis with subjective complaints of diplopia and proptosis [go.galegroup.com]

• Anosmia

  Anosmia after anterior communicating artery aneurysm surgery: Comparison between the anterior interhemispheric and basal interhemispheric approaches. Neurosurgery 1996;38:325-8. [ PUBMED ] 4. Suzuki J, Katakura R, Mori T. [neurologyindia.com]

• Diplopia

  The ocular manifestations included visual loss in 59 (86%), eye pain in six (9%), diplopia in three (4%), and ptosis in one (1%) patient. [jmatonline.com]

  Diplopia indicated a possible tumor mass involving the cavernous sinus. [kjim.org]

  However, this effect is seen in any condition that causes delayed optic nerve conduction such as multiple sclerosis and retinal disorders.[25] Diplopia Diplopia may be due to a paretic diplopia from ocular motor cranial nerve (e.g., III, IV, VI) paresis [eyewiki.aao.org]

  Within months of surgery, the patient’s diplopia and movement of her right eye improved. She had no other neurologic complaints. [barrowneuro.org]

  Visual symptoms and signs include vision loss, diplopia, and multiple cranial nerve palsies secondary to rapid expansion of the tumor into the adjacent cavernous sinuses, with cranial nerve III the most commonly affected. [webeye.ophth.uiowa.edu]

• Vertical Gaze Palsy

  This phenomenon is caused by involvement of midbrain structures adjacent to the pineal GCT and is characterised by vertical gaze palsy, nystagmus on convergence and pupillary dilation with poor reactiveness to light. [tandfonline.com]

• Unilateral Proptosis

  Ewing's sarcoma of the orbit with intracranial extension: A rare cause of unilateral proptosis. J Pediatr Neurosci 2011;6:36-9. [Full text] 3. Weins AL, Hattab EM. The pathological spectrum of solid CNS metastases in the pediatric population. [ruralneuropractice.com]

• Eye Pain

  The ocular manifestations included visual loss in 59 (86%), eye pain in six (9%), diplopia in three (4%), and ptosis in one (1%) patient. [jmatonline.com]

• Headache

  A 45-year-old man was seen for urgent evaluation of worsening headaches and loss of vision. He first noticed his symptoms 6 months before the onset of recurrent headaches with blurry and blank spots in his vision. [healio.com]

  A case report of ectopic pituitary gland in the suprasellar region of a normal 39-year-old woman with persistent headaches is presented. [indiana.pure.elsevier.com]

  A 24-year-old male was presented to the neurosurgery department with a history of headache, diminution of vision of 4 months' duration. [ijem.in]

  nasal obstruction, polydipsia and polyuria, visual disorder, delayed development Headache, nasal obstruction, polydipsia and polyuria, visual disorder, delayed development Headache, nasal obstruction Stereotactic Interstitial brachythera None 10 Obviously [kundoc.com]

• Bitemporal Hemianopsia

  An examination of her visual fields revealed bitemporal hemianopsia. Her corrected visual acuity with eye glasses was insufficient. [semanticscholar.org]

  His vision postoperatively showed a persistent bitemporal hemianopsia, but with significant improvement in visual acuity to 20/40 in the right eye and 20/20 in the left eye. [healio.com]

  Physical examinations were normal except bitemporal hemianopsia revealed by ophthalmic examination. Preoperative neuroendocrine examinations showed a mild hyperprolactinemia of 72.3ng/ml (normal range, 2.8 ng/ml-29.2 ng/ml). [path.upmc.edu]

  […] and suprasellar ND Bitemporal hemianopsia + − Transsphenoidal 5 Whee, 11) 2002 39 M Intrasellar and suprasellar ND Bitemporal hemianopsia + − Transsphenoidal 6 Maatens, 5) 2003 33 F Intrasellar and suprasellar ND Left frontal headache, diminished visual [ncbi.nlm.nih.gov]

  Humphrey visual field 24-2 showing a bitemporal hemianopsia. Figure 2. Goldmann visual field showing a bitemporal hemianopsia.[31] Neuroimaging The pituitary gland is best seen on coronal sections and normally enhances with contrast. [eyewiki.aao.org]

• Long Tract Signs

  The classic triad of presentation—long tract signs, cranial nerve deficits, and ataxia—is seen simultaneously in 35% of patients, but most patients present with at least one of these symptoms [34]. [ajronline.org]

It is crucial to have a multidisciplinary team approach with baseline and follow up endocrine workup. [abstracts.eurospe.org]

[…] massive MRI: High signal intensity on T1 weighted images Heterogeneous enhancement Fluid levels consistent with cystic components CT: Better than MRI at showing calcifications Laboratory Same for both types of craniopharyngiomas Full pituitary endocrine workup [pathologyoutlines.com]

The clinical workup for CNS germ cell tumors includes examination of cerebrospinal fluid (CSF) and blood for markers of differentiation, specifically β-hCG and α-fetoprotein (AFP). [neupsykey.com]

Initial workup, including CT and MRI of the brain is shown (Fig. 1). [jaocr.org]

It is important to note that while a sellar mass may present with bitemporal hemianopia, the combination of findings described above describing a junctional scotoma also localizes to the sellar area, and additional workup is indicated. [webeye.ophth.uiowa.edu]

An accurate diagnosis has important clinical implications related to prognosis and treatment. Pediatric suprasellar tumors are unique in their differential diagnosis and differ from adult tumors in the same region in incidence and treatment. [ajronline.org]

Though many suprasellar lesions are relatively benign in pathology, treatment may be complicated by high surgical morbidity resulting from damage to the hypothalamic-pituitary axis. [pubmed.ncbi.nlm.nih.gov]

Treatment depends upon the underlying cause but often requires surgical decompression. [tuftsmedicalcenter.org]

Learn more about Josephine's treatment and recovery. [mountsinai.org]

It also includes classic radiographic presentations and treatment considerations for each lesion. © The Author(s) 2015. [ncbi.nlm.nih.gov]

Although rare, pure suprasellar germinomas carry worse prognosis than other locations. [ncbi.nlm.nih.gov]

Treatment and prognosis In general, a biopsy is required as treatment and prognosis will vary with histology (whereas it is independent of location). [radiopaedia.org]

Key words: Prognosis; Visual Acuity; Meningioma; Optic Chiasm; Neurosurgical Procedures; Treatment Outcome; Recovery of Function Uvod. [go.gale.com]

The diffuse intrinsic type has the worst prognosis of all brainstem gliomas, with median survival rarely exceeding 9 months [41]. Focal midbrain tumors have a more indolent course and a more favorable prognosis. [ajronline.org]

Prognosis is dependent upon the tumor type, the most common of which is a germinoma which has a peak incidence during pubescence. Prognosis for germinomas is generally good with a 10-year survival rate over 90% after radiation therapy. [jaocr.org]

In 183 short chapters, the book provides the essentials clinicians need on symptoms/signs, diagnostic tests, and neurologic disorders of all etiologies. For this edition, Timothy A. [books.google.es]

[…] signs; (3) endocrine disturbances are highly frequent before surgery, while surgical intervention had little effect in increasing endocrine morbidity; (4) NEC, even though producing less endocrine dysfunctions than other tumor types, are an important etiology [karger.com]

A malignant etiology should be suspected if osteolysis is present. The presentation may be variable between an enlargement of the pituitary stalk or sellar and suprasellar tumor. [neurochirurgica.org]

LCH is a rare disease of uncertain etiology which typically presents in children under two years of age, is more common in boys, and may involve any organ system. [jaocr.org]

We compared the clinical and epidemiological characteristics of bifocal GCTs with those of GCTs located solely in the suprasellar or pineal regions. [thejns.org]

Conclusion Pediatric meningioma is an uncommon and sometimes surprising diagnosis given its epidemiologic, histologic, and clinical features. [cnjournal.biomedcentral.com]

Epidemiology As a general rule, brain tumors increase in frequency with age, with individual exceptions (e.g. pilocytic astrocytoma, the vast majority of which are found in young patients), and a number of uncommon tumors found in infancy (see brain tumors [radiopaedia.org]

Epidemiology: · Average age: 32 years. · 28 women/15 men. [posterng.netkey.at]

Always WHO Grade I Tumor with palisading epithelium, "wet" keratin and stellate reticulum associated with surrounding gliosis and Rosenthal fibers Terminology Epithelial neoplasm resembling ameloblastoma or keratinizing and calcifying odontogenic cyst Epidemiology [pathologyoutlines.com]

It addresses diagnosis, pathophysiology, management and prognosis and is written in a clear, concise style for quick, easy reference in the clinic. [books.google.es]

CNS, SIAD 31 2010 Cerebral salt wasting: pathophysiology, diagnosis, and treatment. --- 32 2010 Characterization of cerebral salt wasting after subarachnoid hemorrhage model induced by endovascular puncture. [allie.dbcls.jp]

PATHOPHYSIOLOGY — With respect to pathophysiology, two issues need to be addressed: the mechanism of salt wasting and the mechanism of hyponatremia. The mechanism by which cerebral disease might lead to renal salt wasting is poorly understood. [docsity.com]

Pathophysiology Hematogenous metastases to this region most frequently go to the pituitary gland, infundibulum, and tuber cinereum, because these structures lie outside the blood-brain barrier. [radiologykey.com]

SIADH is the biochemical manifestation of a wide variety of diseases, and the pathophysiology of SIADH is sometimes… CONTINUE READING Create an AI-powered research feed to stay up to date with new papers like this posted to ArXiv Figures, Tables, and [semanticscholar.org]

Extreme caution was taken to avoid spillage of tumor cyst fluid into subarachnoid spaces, in order to prevent chemical meningitis. [neurologyindia.com]

Orbital inflammations Methysergide for prevention of headache Pseudotumor of the orbit and retroperitoneal fibrosis Multisystem fibrosis in alphalantitrypsin deficiency [semanticscholar.org]

It failed to prevent the recurrence or progression of residual tumor in another 5 patients, occurring from 6 to 60 months after irradiation. [clinicalgate.com]

8055-8051-9 (Print) eISBN: 978-3-318-01300-9 (Online) Abstract The principles in the surgical management of sellar and suprasellar tumors are to relieve mass effect, normalize pituitary hypersecretion, preserve or restore normal pituitary function, prevent [karger.com]