This unusual presentation is discussed and plausible hypotheses are given. [ncbi.nlm.nih.gov]

Eleven patients (47.8%) presenting with bifocal GCTs exhibited tumor seeding at presentation. Tumor seeding was significantly associated with bifocal lesions (p 0.001). [neurosurgery-blog.com]

• Increased Energy

  Leptin is secreted by adipose tissue and binds to hypothalamic receptors to reduce appetite and increase energy expenditure. [journals.lww.com]

• Hyposmia

  Neurological complaints, such as mild mental or motor dysfunction, vertigo, epileptic attack, hyposmia, were present in a much lower degree (from 2.3 to 9.3% of patients) in addition to oculomotor paresis with subjective complaints of diplopia and proptosis [go.galegroup.com]

• Anosmia

  Anosmia after anterior communicating artery aneurysm surgery: Comparison between the anterior interhemispheric and basal interhemispheric approaches. Neurosurgery 1996;38:325-8. [ PUBMED ] 4. Suzuki J, Katakura R, Mori T. [neurologyindia.com]

• Abdominal Distension

  Abdominal distension and hepatomegaly occurred on the 9th postoperative day. [journals.lww.com]

• Liver Fibrosis

  Leptin is an independent marker of liver fibrosis in humans with nonalcoholic fatty liver disease [abstract]. Hepatology 2002;36:296A. 11. Luyckx FH, Lefebvre PJ, Scheen AJ. [journals.lww.com]

• Tinel's Sign

  There was no enlargement of his jaws, hands or feet, or Tinel’s sign. His thyroid was palpable but not enlarged, with no discrete nodules. His eye exam showed normal extraocular movements, and pupils were equal, round and reactive to light. [healio.com]

• Diplopia

  The ocular manifestations included visual loss in 59 (86%), eye pain in six (9%), diplopia in three (4%), and ptosis in one (1%) patient. [jmatonline.com]

  Diplopia indicated a possible tumor mass involving the cavernous sinus. [kjim.org]

  However, this effect is seen in any condition that causes delayed optic nerve conduction such as multiple sclerosis and retinal disorders.[25] Diplopia Diplopia may be due to a paretic diplopia from ocular motor cranial nerve (e.g., III, IV, VI) paresis [eyewiki.aao.org]

  Within months of surgery, the patient’s diplopia and movement of her right eye improved. She had no other neurologic complaints. [barrowneuro.org]

  […] and choriocarcinomas (5%). [2] The parasellar extension and rapid growth can rarely mimic pituitary apoplexy. » Case Reports Case 1 A 13-year-old short-statured boy presented with polyuria, polydypsia and nocturia of six months' duration, headache and diplopia [neurologyindia.com]

• Vertical Gaze Palsy

  This phenomenon is caused by involvement of midbrain structures adjacent to the pineal GCT and is characterised by vertical gaze palsy, nystagmus on convergence and pupillary dilation with poor reactiveness to light. [tandfonline.com]

• Unilateral Proptosis

  Ewing's sarcoma of the orbit with intracranial extension: A rare cause of unilateral proptosis. J Pediatr Neurosci 2011;6:36-9. [Full text] 3. Weins AL, Hattab EM. The pathological spectrum of solid CNS metastases in the pediatric population. [ruralneuropractice.com]

• Eye Pain

  The ocular manifestations included visual loss in 59 (86%), eye pain in six (9%), diplopia in three (4%), and ptosis in one (1%) patient. [jmatonline.com]

• Headache

  Abstract A case report of ectopic pituitary gland in the suprasellar region of a normal 39-year-old woman with persistent headaches is presented. [ncbi.nlm.nih.gov]

  A 45-year-old man was seen for urgent evaluation of worsening headaches and loss of vision. He first noticed his symptoms 6 months before the onset of recurrent headaches with blurry and blank spots in his vision. [healio.com]

  A case report of ectopic pituitary gland in the suprasellar region of a normal 39-year-old woman with persistent headaches is presented. [indiana.pure.elsevier.com]

  A 24-year-old male was presented to the neurosurgery department with a history of headache, diminution of vision of 4 months' duration. [ijem.in]

• Bitemporal Hemianopsia

  An examination of her visual fields revealed bitemporal hemianopsia. Her corrected visual acuity with eye glasses was insufficient. [semanticscholar.org]

  His vision postoperatively showed a persistent bitemporal hemianopsia, but with significant improvement in visual acuity to 20/40 in the right eye and 20/20 in the left eye. [healio.com]

  Physical examinations were normal except bitemporal hemianopsia revealed by ophthalmic examination. Preoperative neuroendocrine examinations showed a mild hyperprolactinemia of 72.3ng/ml (normal range, 2.8 ng/ml-29.2 ng/ml). [path.upmc.edu]

  7 56 F Intrasellar and suprasellar Obstructive Bitemporal hemianopsia, cognitive decline, personality change, gait disturbance Transsphenoidal 8 Esposito, 12) 2004 73 M Intrasellar and suprasellar ND Hyponatremia, bitemporal hemianopsia Transsphenoidal [ncbi.nlm.nih.gov]

  Humphrey visual field 24-2 showing a bitemporal hemianopsia. Figure 2. Goldmann visual field showing a bitemporal hemianopsia.[31] Neuroimaging The pituitary gland is best seen on coronal sections and normally enhances with contrast. [eyewiki.aao.org]

• Long Tract Signs

  The classic triad of presentation—long tract signs, cranial nerve deficits, and ataxia—is seen simultaneously in 35% of patients, but most patients present with at least one of these symptoms [34]. [ajronline.org]

It is crucial to have a multidisciplinary team approach with baseline and follow up endocrine workup. [abstracts.eurospe.org]

[…] massive MRI: High signal intensity on T1 weighted images Heterogeneous enhancement Fluid levels consistent with cystic components CT: Better than MRI at showing calcifications Laboratory Same for both types of craniopharyngiomas Full pituitary endocrine workup [pathologyoutlines.com]

The clinical workup for CNS germ cell tumors includes examination of cerebrospinal fluid (CSF) and blood for markers of differentiation, specifically β-hCG and α-fetoprotein (AFP). [neupsykey.com]

Initial workup, including CT and MRI of the brain is shown (Fig. 1). [jaocr.org]

It is important to note that while a sellar mass may present with bitemporal hemianopia, the combination of findings described above describing a junctional scotoma also localizes to the sellar area, and additional workup is indicated. [webeye.ophth.uiowa.edu]

• Liver Biopsy

  The role of liver biopsy in fatty liver disease is contentious, not least because liver biopsy carries a finite risk of death ( 6 ) and the prognosis of NAFLD acquired in childhood is not yet known. [journals.lww.com]

Combination treatment with metformin and pioglitazone was markedly effective in improving glycemic control. Additionally, metformin treatment showed marked anorectic effects on the hyperphagia. [ncbi.nlm.nih.gov]

However, treatment strategies of adult ATRT may be different from that of pediatric ATRT. [btrt.org]

To round out the clinician's understanding of the illness, a patient describes the experience of diagnosis, treatment, and follow-up. [books.google.ro]

Although rare, pure suprasellar germinomas carry worse prognosis than other locations. [ncbi.nlm.nih.gov]

The prognosis associated with bifocal GCTs has also been a cause of concern. Methods. The authors constructed a single-institution patient cohort comprising 181 patients with intracranial GCTs. [neurosurgery-blog.com]

These studies can aid in the differentiation between CNS PNET and medulloblastoma, and also indicate prognosis and clinical outcome. [journals.lww.com]

It addresses diagnosis, pathophysiology, management and prognosis and is written in a clear, concise style for quick, easy reference in the clinic. [books.google.es]

The diffuse intrinsic type has the worst prognosis of all brainstem gliomas, with median survival rarely exceeding 9 months [41]. Focal midbrain tumors have a more indolent course and a more favorable prognosis. [ajronline.org]

In 183 short chapters, the book provides the essentials clinicians need on symptoms/signs, diagnostic tests, and neurologic disorders of all etiologies. For this edition, Timothy A. [books.google.es]

[…] signs; (3) endocrine disturbances are highly frequent before surgery, while surgical intervention had little effect in increasing endocrine morbidity; (4) NEC, even though producing less endocrine dysfunctions than other tumor types, are an important etiology [karger.com]

Although more experiences based on sub-classified etiology for internal carotid artery stenosis are required, various types of operations including intracranial-extracranial vascular surgery might be justified based on this principle. [ncbi.nlm.nih.gov]

We compared the clinical and epidemiological characteristics of bifocal GCTs with those of GCTs located solely in the suprasellar or pineal regions. [thejns.org]

Epidemiology As a general rule, brain tumors increase in frequency with age, with individual exceptions (e.g. pilocytic astrocytoma, the vast majority of which are found in young patients), and a number of uncommon tumors found in infancy (see brain tumors [radiopaedia.org]

Epidemiology: · Average age: 32 years. · 28 women/15 men. [posterng.netkey.at]

The epidemiology and long-term prognosis of fatty liver disease in children is not known. Hepatic steatosis occurs in many chronic liver diseases, some of which are amenable to treatment, such as Wilson’s disease and inherited metabolic diseases. [journals.lww.com]

It addresses diagnosis, pathophysiology, management and prognosis and is written in a clear, concise style for quick, easy reference in the clinic. [books.google.es]

CNS, SIAD 31 2010 Cerebral salt wasting: pathophysiology, diagnosis, and treatment. --- 32 2010 Characterization of cerebral salt wasting after subarachnoid hemorrhage model induced by endovascular puncture. [allie.dbcls.jp]

SIADH is the biochemical manifestation of a wide variety of diseases, and the pathophysiology of SIADH is sometimes… CONTINUE READING Create an AI-powered research feed to stay up to date with new papers like this posted to ArXiv Figures, Tables, and [semanticscholar.org]

PATHOPHYSIOLOGY — With respect to pathophysiology, two issues need to be addressed: the mechanism of salt wasting and the mechanism of hyponatremia. The mechanism by which cerebral disease might lead to renal salt wasting is poorly understood. [docsity.com]

Pathophysiology Hematogenous metastases to this region most frequently go to the pituitary gland, infundibulum, and tuber cinereum, because these structures lie outside the blood-brain barrier. [radiologykey.com]

Extreme caution was taken to avoid spillage of tumor cyst fluid into subarachnoid spaces, in order to prevent chemical meningitis. [neurologyindia.com]

It failed to prevent the recurrence or progression of residual tumor in another 5 patients, occurring from 6 to 60 months after irradiation. [clinicalgate.com]

In an effort to prevent further weight gain, a low-fat diet was introduced, but compliance was poor because of hyperphagia. [journals.lww.com]

Abstract Background Treatment strategy to prevent perioperative cerebral infarction in patients with asymptomatic severe stenosis of the internal carotid artery is not fully established. [ncbi.nlm.nih.gov]