This unusual presentation is discussed and plausible hypotheses are given. [ncbi.nlm.nih.gov]

Synopsis Our patient is a 60-year-old male who presented with hypogonadism and possible mild diabetes insipidus. MRI revealed an atypical suprasellar mass which was excised using an expanded endoscopic endonasal approach. [pituitary.ucla.edu]

Clinical presentation of the patients:  Clinical presentation of the patients depends upon the size of the tumor and the type of the tumor. Depending upon the size tumors are divided into 2 types: Large tumors(macro-adenomas). [slideshare.net]

• Hyposmia

  Neurological complaints, such as mild mental or motor dysfunction, vertigo, epileptic attack, hyposmia, were present in a much lower degree (from 2.3 to 9.3% of patients) in addition to oculomotor paresis with subjective complaints of diplopia and proptosis [go.galegroup.com]

• Anosmia

  Anosmia after anterior communicating artery aneurysm surgery: Comparison between the anterior interhemispheric and basal interhemispheric approaches. Neurosurgery 1996;38:325-8. [ PUBMED ] 4. Suzuki J, Katakura R, Mori T. [neurologyindia.com]

• Liver Fibrosis

  Leptin is an independent marker of liver fibrosis in humans with nonalcoholic fatty liver disease [abstract]. Hepatology 2002;36:296A. 11. Luyckx FH, Lefebvre PJ, Scheen AJ. [journals.lww.com]

• Tinel's Sign

  There was no enlargement of his jaws, hands or feet, or Tinel’s sign. His thyroid was palpable but not enlarged, with no discrete nodules. His eye exam showed normal extraocular movements, and pupils were equal, round and reactive to light. [healio.com]

• Diplopia

  The ocular manifestations included visual loss in 59 (86%), eye pain in six (9%), diplopia in three (4%), and ptosis in one (1%) patient. [jmatonline.com]

  Diplopia indicated a possible tumor mass involving the cavernous sinus. [kjim.org]

  However, this effect is seen in any condition that causes delayed optic nerve conduction such as multiple sclerosis and retinal disorders.[25] Diplopia Diplopia may be due to a paretic diplopia from ocular motor cranial nerve (e.g., III, IV, VI) paresis [eyewiki.aao.org]

  Within months of surgery, the patient’s diplopia and movement of her right eye improved. She had no other neurologic complaints. [barrowneuro.org]

  Visual symptoms and signs include vision loss, diplopia, and multiple cranial nerve palsies secondary to rapid expansion of the tumor into the adjacent cavernous sinuses, with cranial nerve III the most commonly affected. [webeye.ophth.uiowa.edu]

• Vertical Gaze Palsy

  This phenomenon is caused by involvement of midbrain structures adjacent to the pineal GCT and is characterised by vertical gaze palsy, nystagmus on convergence and pupillary dilation with poor reactiveness to light. [tandfonline.com]

• Unilateral Proptosis

  Ewing's sarcoma of the orbit with intracranial extension: A rare cause of unilateral proptosis. J Pediatr Neurosci 2011;6:36-9. [Full text] 3. Weins AL, Hattab EM. The pathological spectrum of solid CNS metastases in the pediatric population. [ruralneuropractice.com]

• Eye Pain

  The ocular manifestations included visual loss in 59 (86%), eye pain in six (9%), diplopia in three (4%), and ptosis in one (1%) patient. [jmatonline.com]

• Headache

  A 45-year-old man was seen for urgent evaluation of worsening headaches and loss of vision. He first noticed his symptoms 6 months before the onset of recurrent headaches with blurry and blank spots in his vision. [healio.com]

  A case report of ectopic pituitary gland in the suprasellar region of a normal 39-year-old woman with persistent headaches is presented. [indiana.pure.elsevier.com]

  A 24-year-old male was presented to the neurosurgery department with a history of headache, diminution of vision of 4 months' duration. [ijem.in]

  nasal obstruction, polydipsia and polyuria, visual disorder, delayed development Headache, nasal obstruction, polydipsia and polyuria, visual disorder, delayed development Headache, nasal obstruction Stereotactic Interstitial brachythera None 10 Obviously [kundoc.com]

• Bitemporal Hemianopsia

  An examination of her visual fields revealed bitemporal hemianopsia. Her corrected visual acuity with eye glasses was insufficient. [semanticscholar.org]

  His vision postoperatively showed a persistent bitemporal hemianopsia, but with significant improvement in visual acuity to 20/40 in the right eye and 20/20 in the left eye. [healio.com]

  Physical examinations were normal except bitemporal hemianopsia revealed by ophthalmic examination. Preoperative neuroendocrine examinations showed a mild hyperprolactinemia of 72.3ng/ml (normal range, 2.8 ng/ml-29.2 ng/ml). [path.upmc.edu]

  […] and suprasellar ND Bitemporal hemianopsia + − Transsphenoidal 5 Whee, 11) 2002 39 M Intrasellar and suprasellar ND Bitemporal hemianopsia + − Transsphenoidal 6 Maatens, 5) 2003 33 F Intrasellar and suprasellar ND Left frontal headache, diminished visual [ncbi.nlm.nih.gov]

  Humphrey visual field 24-2 showing a bitemporal hemianopsia. Figure 2. Goldmann visual field showing a bitemporal hemianopsia.[31] Neuroimaging The pituitary gland is best seen on coronal sections and normally enhances with contrast. [eyewiki.aao.org]

• Long Tract Signs

  The classic triad of presentation—long tract signs, cranial nerve deficits, and ataxia—is seen simultaneously in 35% of patients, but most patients present with at least one of these symptoms [34]. [ajronline.org]

It is crucial to have a multidisciplinary team approach with baseline and follow up endocrine workup. [abstracts.eurospe.org]

[…] massive MRI: High signal intensity on T1 weighted images Heterogeneous enhancement Fluid levels consistent with cystic components CT: Better than MRI at showing calcifications Laboratory Same for both types of craniopharyngiomas Full pituitary endocrine workup [pathologyoutlines.com]

The clinical workup for CNS germ cell tumors includes examination of cerebrospinal fluid (CSF) and blood for markers of differentiation, specifically β-hCG and α-fetoprotein (AFP). [neupsykey.com]

Initial workup, including CT and MRI of the brain is shown (Fig. 1). [jaocr.org]

It is important to note that while a sellar mass may present with bitemporal hemianopia, the combination of findings described above describing a junctional scotoma also localizes to the sellar area, and additional workup is indicated. [webeye.ophth.uiowa.edu]

• Pulmonary Infiltrate

  A repeat CT scan of the thorax, abdomen, and pelvis showed extensive metastatic disease involving mediastinal, subcarinal, and hilar lymph nodes, causing occlusion of the right main bronchus and right pulmonary infiltrates. [thejns.org]

• Liver Biopsy

  The role of liver biopsy in fatty liver disease is contentious, not least because liver biopsy carries a finite risk of death ( 6 ) and the prognosis of NAFLD acquired in childhood is not yet known. [journals.lww.com]

It also includes classic radiographic presentations and treatment considerations for each lesion. © The Author(s) 2015. [ncbi.nlm.nih.gov]

Treatment Selection: Treatment choice depends upon the 1. Presenting problems and patient’s reuirements. 2. Patient’s age. 3. Preference and experience of the treatment centre. [slideshare.net]

However, treatment strategies of adult ATRT may be different from that of pediatric ATRT. [btrt.org]

Treatment depends upon the underlying cause but often requires surgical decompression. [tuftsmedicalcenter.org]

Although rare, pure suprasellar germinomas carry worse prognosis than other locations. [ncbi.nlm.nih.gov]

Treatment and prognosis In general, a biopsy is required as treatment and prognosis will vary with histology (whereas it is independent of location). [radiopaedia.org]

Key words: Prognosis; Visual Acuity; Meningioma; Optic Chiasm; Neurosurgical Procedures; Treatment Outcome; Recovery of Function Uvod. [go.gale.com]

Prognosis is dependent upon the tumor type, the most common of which is a germinoma which has a peak incidence during pubescence. Prognosis for germinomas is generally good with a 10-year survival rate over 90% after radiation therapy. [jaocr.org]

Prognosis A prognosis is an estimate of the likely progress of a disease after a diagnosis, based on an average patient group. [braintumour.ca]

In 183 short chapters, the book provides the essentials clinicians need on symptoms/signs, diagnostic tests, and neurologic disorders of all etiologies. For this edition, Timothy A. [books.google.es]

[…] signs; (3) endocrine disturbances are highly frequent before surgery, while surgical intervention had little effect in increasing endocrine morbidity; (4) NEC, even though producing less endocrine dysfunctions than other tumor types, are an important etiology [karger.com]

A malignant etiology should be suspected if osteolysis is present. The presentation may be variable between an enlargement of the pituitary stalk or sellar and suprasellar tumor. [neurochirurgica.org]

LCH is a rare disease of uncertain etiology which typically presents in children under two years of age, is more common in boys, and may involve any organ system. [jaocr.org]

Epidemiology As a general rule, brain tumors increase in frequency with age, with individual exceptions (e.g. pilocytic astrocytoma, the vast majority of which are found in young patients), and a number of uncommon tumors found in infancy (see brain tumors [radiopaedia.org]

We compared the clinical and epidemiological characteristics of bifocal GCTs with those of GCTs located solely in the suprasellar or pineal regions. [thejns.org]

Epidemiology: · Average age: 32 years. · 28 women/15 men. [posterng.netkey.at]

Always WHO Grade I Tumor with palisading epithelium, "wet" keratin and stellate reticulum associated with surrounding gliosis and Rosenthal fibers Terminology Epithelial neoplasm resembling ameloblastoma or keratinizing and calcifying odontogenic cyst Epidemiology [pathologyoutlines.com]

Jun 23rd, 2018 - The association between increasing body mass index (BMI; calculated as weight in kilograms divided by height in meters squared) and risk of breast cancer is unique in cancer epidemiology in that a crossover effect exists, with risk reduction [allmedx.com]

It addresses diagnosis, pathophysiology, management and prognosis and is written in a clear, concise style for quick, easy reference in the clinic. [books.google.es]

CNS, SIAD 31 2010 Cerebral salt wasting: pathophysiology, diagnosis, and treatment. --- 32 2010 Characterization of cerebral salt wasting after subarachnoid hemorrhage model induced by endovascular puncture. [allie.dbcls.jp]

PATHOPHYSIOLOGY — With respect to pathophysiology, two issues need to be addressed: the mechanism of salt wasting and the mechanism of hyponatremia. The mechanism by which cerebral disease might lead to renal salt wasting is poorly understood. [docsity.com]

Pathophysiology Hematogenous metastases to this region most frequently go to the pituitary gland, infundibulum, and tuber cinereum, because these structures lie outside the blood-brain barrier. [radiologykey.com]

SIADH is the biochemical manifestation of a wide variety of diseases, and the pathophysiology of SIADH is sometimes… CONTINUE READING Create an AI-powered research feed to stay up to date with new papers like this posted to ArXiv Figures, Tables, and [semanticscholar.org]

Extreme caution was taken to avoid spillage of tumor cyst fluid into subarachnoid spaces, in order to prevent chemical meningitis. [neurologyindia.com]

Orbital inflammations Methysergide for prevention of headache Pseudotumor of the orbit and retroperitoneal fibrosis Multisystem fibrosis in alphalantitrypsin deficiency [semanticscholar.org]

It failed to prevent the recurrence or progression of residual tumor in another 5 patients, occurring from 6 to 60 months after irradiation. [clinicalgate.com]

8055-8051-9 (Print) eISBN: 978-3-318-01300-9 (Online) Abstract The principles in the surgical management of sellar and suprasellar tumors are to relieve mass effect, normalize pituitary hypersecretion, preserve or restore normal pituitary function, prevent [karger.com]