Presentation
Histological examination revealed a chondrosarcoma, which on the basis of imaging findings we present as having arisen from the synovium. [ncbi.nlm.nih.gov]
There can be a wide spectrum in age of presentation from from 25-75 years of age. A slight male predilection may be present. It can either as a primary lesion (primary synovial chondrosarcoma) or secondary to synovial chondromatosis. [radiopaedia.org]
Entire Body System
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Soft Tissue Mass
On MR imaging, the lobulated contours of the soft tissue mass suggested synovial chondromatosis. Histological examination revealed a chondrosarcoma, which on the basis of imaging findings we present as having arisen from the synovium. [ncbi.nlm.nih.gov]
[…] synovial osteochondromatosis Multiple cartilaginous calcified and ossified nodules 40-70 years Commonly involves knee and hip Distant metastases in lungs Imaging: Differentiation from synovial osteochondromatosis is difficult Radiograph: Intraarticular soft-tissue [musculoskeletal-radiology.blogspot.com]
tissue mass Top: Multiple nodular calcifications surrounding the right shoulder in synovial osteochondromatosis. [learningradiology.com]
Keywords Synovial chondrosarcoma Synovial chondromatosis Intraarticular soft tissue mass MRI Histology This is a preview of subscription content, log in to check access. References 1. Bertoni F, Unni KK, Beabout JW, Sim FH. [link.springer.com]
High-grade features include faint amorphous calcifications, large noncalcified areas, and concentric growth of a soft-tissue mass. [orthoinfo.aaos.org]
Respiratoric
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Aspiration
Fine needle aspiration biopsy revealed an atypical chondroid lesion that was supicious for a chondrosarcoma. [ncbi.nlm.nih.gov]
The lesion was removed in piecemeal fashion using curettes and Cavitron ultrasonic surgical aspirator. Histological examination demonstrated atypical well-differentiated cartilaginous proliferation. [surgicalneurologyint.com]
Fine-needle aspiration biopsy of skeletal versus extraskeletal osteosarcoma. Cancer 1998; 8: 176-85. 18. Lee JS, Fetsch JF, Wasdhal DA, Lee BP, Pritchard DJ, Nascimento AG. A review of 40 patients with extraskeletal osteosarcoma. [ispub.com]
Musculoskeletal
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Knee Pain
Abstract We report the case of a 51-year-old woman who had suffered from right knee pain and stiffness for 40 years. Her symptoms had gradually worsened over the past 5 years. [ncbi.nlm.nih.gov]
AB - We report the case of a 51-year-old woman who had suffered from right knee pain and stiffness for 40 years. Her symptoms had gradually worsened over the past 5 years. [tmu.pure.elsevier.com]
pain and stiffness for 40 years. [jbsr.be]
A 48-year-old countryside Chinese woman presented with a history of progressively worsening right knee pain with associated swelling, and stiffness for the past three months after she has been suffering from recurrent wild right knee pain since she endured [orthopedics.imedpub.com]
Available from: A 67-year-old woman with a history of bilateral progressive knee pain and swelling for a long while was referred for 99m Tc-methyl diphosphonate ( 99m Tc-MDP) bone scintigraphy. [ijnm.in]
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Joint Effusion
Additional radiographic findings include joint effusion and degenerative changes such as joint space narrowing, subchondral sclerosis, and osteophyte formation. [en.wikipedia.org]
Joint effusions and synovial thickening are commonly seen. The synovial thickening is best seen on postcontrast T1 fat-suppressed images. [jaocr.org]
[…] more common in men than women · Usually in 3 rd -5 th decade · Knee is most frequent site of involvement, followed by o Elbow o Hip o Shoulder o Ankle o Wrist o Pain § Usually chronic and progressive o Swelling o Limitation of movement (lock knee) o Joint [learningradiology.com]
Bone fragments are seen both anteriorly and posteriorly Click here to view Figure 4: MRI scan of the left elbow showing joint effusion without evidence of bony injury. [ijoonline.com]
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Joint Swelling
These often are characterized by joint swelling, pain and joint dysfunction. [annalidistomatologia.com]
Patients usually complain of mechanical pain (85 of 100% cases), joint swelling (42%–58%) and restricted joint mobility (38%–55%) [ 1 ]. [em-consulte.com]
These include: Joint pain Joint swelling Limited range of motion in the affected joint Other signs and symptoms may include: Fluid in the joint Tenderness A creaking, grinding, or popping noise during movement (crepitus) The nodules can sometimes be felt [orthoinfo.aaos.org]
Psychiatrical
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Suggestibility
On MR imaging, the lobulated contours of the soft tissue mass suggested synovial chondromatosis. Histological examination revealed a chondrosarcoma, which on the basis of imaging findings we present as having arisen from the synovium. [ncbi.nlm.nih.gov]
This would suggest that for every 800 chondrosarcomas diagnosed, 5 originated in synovial chondromatosis; that is, 0.6% of chondrosarcomas are linked to primary synovial chondromatosis. [hindawi.com]
MRI Signal characteristics of particular nodules include T1: low to intermediate signal intensity of nodules T2: high signal intensity in general with hypointense calcifications On contrast to synovial chondromatosis, some imaging features are suggestive [radiopaedia.org]
Neurologic
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Excitement
This exciting new, full-color reference provides you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children with cancer. [books.google.com]
Dear Reader, We are very excited about New Features in JOCR. Please do let us know what you think by Clicking on the Sliding “Feedback Form” button on the [jocr.co.in]
Workup
Laboratory workup revealed a normal white blood cell count: 7000/mm (normal; 4500-10,000/mm), a normal C-reactive protein: 1.0 mg/L (normal; 0-4 mg/L), and mildly elevated erythrocyte sedimentation rate count: 22 mm/h (normal; 20 mm/h). [sjosm.org]
Treatment
The treatment must be a wide resection or an amputation. [ncbi.nlm.nih.gov]
Treatment and prognosis It is a malignant lesions which can metastasize. [radiopaedia.org]
Make informed clinical choices for each patient, from diagnosis and treatment selection through post-treatment strategies and management of complications, with new evidence-based criteria throughout. [books.google.com]
Regarding treatment for SCH, only 14 patients underwent limb-salvage surgery. Amputations were performed in 40 patients (59.7%). Five patients refused hemipelvectomy and in 5 cases treatment was not reported. [atm.amegroups.com]
Prognosis
Treatment and prognosis It is a malignant lesions which can metastasize. [radiopaedia.org]
CONCLUSIONS: We concluded that prognosis of SCH is worse than conventional one and we speculated this is due to the difficult site of the tumor (intraarticular), diagnostic delay and inappropriate previous treatments. [ncbi.nlm.nih.gov]
According to Campanacci et al. the prognosis of SCH is comparable to that of conventional CHS and depends on the histological grade of malignancy of the lesion (1). [atm.amegroups.com]
Etiology
No etiological factors can be indicated, even though in some cases there is a history of trauma. No familiar cases were reported. Surgery ended up with amputation in 59.7% of cases. Local recurrence rate was 28.3%. [atm.amegroups.com]
ETIOLOGY: The etiology of synovial chondromatosis is not known. Some suspect that it is due to synovial irritation. This may be from trauma or possibly from infection, but this is unclear. No organism has ever been cultured. [gait.aidi.udel.edu]
Introduction Also known as synovial chondro-metaplasia Rare condition of unclear etiology in which foci of cartilage develop in the synovial membrane of joints, bursae, or tendon sheaths as a result of metaplasia of the subsynovial connective tissue Nodules [orthopaedicsone.com]
The true etiology remains unknown, but the metaplastic theory is the most favored. [orthopedics.imedpub.com]
Epidemiology
Fraire Extraarticular synovial chondromatosis: review of epidemiology, imaging studies, microscopy and patogénesis, with a report of an additional case in a child Int J Surg Pathol, 12 (2004), pp. 273-280 [14.] F.R. Convery, R. Luon, C. [reumatologiaclinica.org]
The epidemiology of sarcoma. Clinical Sarcoma Research. 2012 Oct; 2(14). SarcomaHelp.org provides professionally reviewed information about sarcomas and their treatment. [sarcomahelp.org]
CHONDROSARCOMA OVERVIEW 1.Defination 2.Frequency 3.Types Defination c/f Frequency radiology Epidemiology histology Etiology 4.Treatment 3. CHONDROSARCOMA DEFINATION Malignant tumour of cartilage producing cells 4. [slideshare.net]
Ko E, Mortimer E, Fraire AE (2004) Extraarticular synovial chondromatosis: review of epidemiology, imaging studies, microscopy and pathogenesis, with a report of an additional case in a child. Int J SurgPathol 12: 273-280. [omicsonline.org]
RadioGraphics 15:893–917 PubMed Google Scholar Myers BW, Massi AT, Feigenbaum SL (1980) Pigmented villonodular synovitis and tenosynovitis: A clinical epidemiologic study of 166 cases and literature review. [link.springer.com]
Pathophysiology
It brings together the pathophysiology of disease with detailed clinical guidance on diagnosis and management for the full range of childhood cancers, including aspects important in optimal supportive care. [books.google.com]
Pathophysiology of Orthopaedic Disease. Rosemont: The American Academy of Orthopaedic Surgeon, 2006:53-8. Darfam MD, Czerniak B. Synovial Lesions. In: Bone Tumours. Mosby, St. Louis, Mo, USA: 1998:1041-86. Murphy FP, Dahlin DC, Sullivan CR. [atm.amegroups.com]
Prevention
It is important to seek treatment for synovial chondromatosis as early as possible to help relieve painful symptoms and prevent the progression of osteoarthritis in the joint. [orthoinfo.aaos.org]
Lateral mass screws were required for stabilization to prevent postlaminectomy kyphosis. The patient improved after the surgery, demonstrating complete recovery in his sensory symptoms and no motor deficits. [surgicalneurologyint.com]
In other words surgical removal may not prevent development of arthritis in the affected joint. Fig. 1 Fig. 2 Fig. 1 & 2. Plain X rays of right shoulder synovial chondromatosis. [tumorsurgery.org]
Plain radiographs may be normal and may require further investigations – such as arthrogram, MRI, or arthroscopy – to make diagnosis Treatment is controversial Removal of loose bodies can be done with or without total synovectomy Alleviates symptoms and prevents [orthopaedicsone.com]