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Synovitis


Presentation

  • We present a patient who developed polyarticular synovitis after treatment with alendronate and responded to its withdrawal.[ncbi.nlm.nih.gov]
Edema of the Hand
  • At week 4, before the 3rd infusion, he presented with inflammatory arthralgia, synovitis of proximal interphalangeal, wrist and ankle joints, and edema of both hands and forearms.[ncbi.nlm.nih.gov]
Wheelchair Bound
  • On evaluation, he was wheelchair bound and completely dependent for all activities of daily living. Evaluation revealed negative serological testing and plain film imaging.[ncbi.nlm.nih.gov]
Cutaneous Manifestation
  • Synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome represents the rare co-occurrence of sterile inflammatory osteoarticular disease in association with a variety of cutaneous manifestations. Oral involvement is uncommon.[ncbi.nlm.nih.gov]
Heel Pain
  • We present a case of lateral heel pain after triple arthrodesis due to synovitis of the tarsal canal that was successfully treated with anterior subtalar arthroscopy.[ncbi.nlm.nih.gov]
Osteoporosis
  • We present a case of polyarticular synovitis following alendronate treatment for osteoporosis. The patient had no evidence of rheumatoid arthritis, pyrophosphate arthropathy, or seronegative/seropositive arthritis.[ncbi.nlm.nih.gov]
Personality Change
  • Paired t-tests were used to determine within person change in outcome measures and Spearman's correlation coefficients were used to determine the correlation between change in pain and change in the DCE parameters.[ncbi.nlm.nih.gov]

Workup

  • Preoperative workup for infection and intraoperative cultures taken at the time of revision surgery were negative for infection.[healio.com]

Treatment

  • We present a patient who developed polyarticular synovitis after treatment with alendronate and responded to its withdrawal.[ncbi.nlm.nih.gov]

Prognosis

  • Although the exact aetiology is not clear, yet it responds dramatically to low doses of steroids with excellent prognosis unlike RA and PMR.[ncbi.nlm.nih.gov]
  • While the prognosis for transient synovitis is generally good, the experience with this series of patients indicates that LCP disease may be antedated by a stage of synovitis indistinguishable from transient, self-limiting synovitis.[pediatrics.aappublications.org]

Etiology

  • The most affected joint from bleeding is the knee whatever the etiology is. Repeated hemarthrosis may produce significant structural alteration of joints leading to chronic osteoarthritis.[ncbi.nlm.nih.gov]
  • Some have suggested a viral etiology (e.g. related to Parvovirus B-19 and /or Herpes simplex virus 6 infections while others have proposed a post-traumatic etiology with subsequent development of chemical synovitis.[radiopaedia.org]

Epidemiology

  • Author information 1 Arthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, Faculty of Medical and Human Sciences, Manchester Academic Health Science Centre, University of Manchester, Stopford Building, Oxford Road, Manchester[ncbi.nlm.nih.gov]
  • […] foot M67.98 - Unspecified disorder of synovium and tendon, other site M67.99 - Unspecified disorder of synovium and tendon, multiple sites Transient Synovitis ICD-9 727.9 Unspecified disorder of synovium, tendon and bursa Transient Synovitis Etiology / Epidemiology[eorif.com]
  • Introduction Overview inflammation of the synovium and a common cause of hip pain in pediatric patients that must be differentiated from septic arthritis of the hip treatment is usually anti-inflammatories and supportive measures given self-limiting nature Epidemiology[orthobullets.com]
Sex distribution
Age distribution

Pathophysiology

  • […] risk factors the exact cause of transient synovitis is largely unknown, however, may be related to viral infection (upper respiratory) bacterial infection ( poststreptococcal toxic synovitis ) trauma higher interferon concentration allergic reaction Pathophysiology[orthobullets.com]
  • Synovial pathophysiology Normal synovium The synovium is a specialized connective tissue that lines diarthrodial joints, surrounds tendons and forms the lining of bursae and fat pads.[arthritis-research.biomedcentral.com]
  • Cause and Pathophysiology of Transient Synovitis Hip The exact cause is unknown.[boneandspine.com]
  • Numerous pathophysiologic mechanisms, including inflammation (multinucleated giant cells), response to antecedent trauma, repeated hemorrhage into the joint (hemosiderin), and disorders of lipid metabolism (xanthoma cells), have been proposed. [4] PVNS[emedicine.medscape.com]

Prevention

  • Regular factor treatment will help prevent further bleeding. This will give the synovial membrane a chance to return to normal. Oral steroids. These are drugs that reduce inflammation.[hog.org]
  • How do I prevent knee synovitis? The main way to prevent knee synovitis symptoms is to protect your knees from injury. Even with the most preparation and caution, injuries happen.[drburkeortho.com]
  • CONCLUSIONS: Treatment with CS had a sustained beneficial effect, preventing synovitis onset or reducing its presence as well as reducing KOA symptoms. ACT ameliorated clinical symptoms but had no effect on inflammation.[ncbi.nlm.nih.gov]
  • For synovitis of the knee caused by arthritis, the best prevention is to continue therapy as prescribed.[livestrong.com]

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