We present a patient who developed polyarticular synovitis after treatment with alendronate and responded to its withdrawal. [ncbi.nlm.nih.gov]

[…] and were over 99% if all 4 predictors were present; - authors recommend careful observation without aspiration if none of the four independent predictors are present; - reference: - Differentiating between septic arthritis and transient synovitis of [wheelessonline.com]

Therefore it is suggested that blood cultures and nucleic acid amplification assay should be performed in young children presenting with irritation of the hip, even when fever, raised WBC count and a high Kocher score is not present.] [boneandspine.com]

• Recent Upper Respiratory Infection

  […] history of disease usually benign marked improvement, usually in 24-48 hours complete resolution of symptoms will usually occur in 1-2 weeks Presentation History recent upper respiratory infection or trauma Symptoms mild or absent fever acute or insidious [orthobullets.com]

• Obturator Sign

  Hefke and Turner (7) described the swelling of the obturator internus as an early x-ray sign of infectious arthritis of the hip joint and called it the “obturator sign.” [pubs.rsna.org]

  Other studies have reported a positive obturator sign in established incidents of transient synovitis. This is a prominent shadow caused by the soft tissues that overlie the interpelvic aspect of the acetabulum. [emedicine.medscape.com]

Preoperative workup for infection and intraoperative cultures taken at the time of revision surgery were negative for infection. [healio.com]

Workup Laboratory Studies The following studies may be indicated in transient synovitis (TS): CBC count: The white blood cell (WBC) count may be slightly elevated. [emedicine.medscape.com]

Septic arthritis workup. Medscape Reference. Available online at http://emedicine.medscape.com/article/236299-workup#c8. Accessed 9/9/2016. Sofronescu, A. (Updated 2016 April 13). Joint fluid interpretation. Medscape Reference. [labtestsonline.org]

Serologic workup performed showed a negative rheumatoid factor, a white blood cell count of 6000 cells/mm3, a C-reactive protein of 0.6 mg/L, and a sedimentation rate of 15 mm in the first hour. [ncbi.nlm.nih.gov]

• Kingella

  Differentiating Kingella kingae Septic Arthritis of the Hip from Transient Synovitis in Young Children. J Pediatr. 2014 Sep 9. [Medline]. Luhmann SJ, Jones A, Schootman M, et al. [medscape.com]

We present a patient who developed polyarticular synovitis after treatment with alendronate and responded to its withdrawal. [ncbi.nlm.nih.gov]

The medical team will start a treatment plan that may include one or more of these: Prophylactic treatment with factor. Regular factor treatment will help prevent further bleeding. This will give the synovial membrane a chance to return to normal. [hog.org]

While the prognosis for transient synovitis is generally good, the experience with this series of patients indicates that LCP disease may be antedated by a stage of synovitis indistinguishable from transient, self-limiting synovitis. [pediatrics.aappublications.org]

Although the exact aetiology is not clear, yet it responds dramatically to low doses of steroids with excellent prognosis unlike RA and PMR. [ncbi.nlm.nih.gov]

The most affected joint from bleeding is the knee whatever the etiology is. Repeated hemarthrosis may produce significant structural alteration of joints leading to chronic osteoarthritis. [ncbi.nlm.nih.gov]

Some have suggested a viral etiology (e.g. related to Parvovirus B-19 and /or Herpes simplex virus 6 infections while others have proposed a post-traumatic etiology with subsequent development of chemical synovitis. [radiopaedia.org]

Author information 1 Arthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, Faculty of Medical and Human Sciences, Manchester Academic Health Science Centre, University of Manchester, Stopford Building, Oxford Road, Manchester [ncbi.nlm.nih.gov]

[…] foot M67.98 - Unspecified disorder of synovium and tendon, other site M67.99 - Unspecified disorder of synovium and tendon, multiple sites Transient Synovitis ICD-9 727.9 Unspecified disorder of synovium, tendon and bursa Transient Synovitis Etiology / Epidemiology [eorif.com]

Introduction Overview inflammation of the synovium and a common cause of hip pain in pediatric patients that must be differentiated from septic arthritis of the hip treatment is usually anti-inflammatories and supportive measures given self-limiting nature Epidemiology [orthobullets.com]

[…] risk factors the exact cause of transient synovitis is largely unknown, however, may be related to viral infection (upper respiratory) bacterial infection ( poststreptococcal toxic synovitis ) trauma higher interferon concentration allergic reaction Pathophysiology [orthobullets.com]

Clinical and pathophysiologic relevance of autoantibodies in rheumatoid arthritis. Adv Rheumatol. 2019;59(1):2. doi:10.1186/s42358-018-0042-8 Brasington RD. Rheumatology (Sixth Edition); 85 - Clinical features of rheumatoid arthritis. 2014. [verywellhealth.com]

Also, the study of enthesitis pathophysiology is limited by the difficulty to obtaining biopsies from the enthesis due to potential adverse effects. [frontiersin.org]

Synovial pathophysiology Normal synovium The synovium is a specialized connective tissue that lines diarthrodial joints, surrounds tendons and forms the lining of bursae and fat pads. [arthritis-research.biomedcentral.com]

Regular factor treatment will help prevent further bleeding. This will give the synovial membrane a chance to return to normal. Oral steroids. These are drugs that reduce inflammation. [hog.org]

[…] en Indications: For the treatment of CRD and pasteurellosis; synovitis in turkey. sl Če je vse pod nadzorom, bom zunaj en Indications: Treatment and prevention of respiratory and gastrointestinal diseases caused by organism sensitive to doxycycline: broilers [sl.glosbe.com]

How do I prevent knee synovitis? The main way to prevent knee synovitis symptoms is to protect your knees from injury. Even with the most preparation and caution, injuries happen. [drburkeortho.com]

For synovitis of the knee caused by arthritis, the best prevention is to continue therapy as prescribed. [livestrong.com]