Presentation
We present a patient who developed polyarticular synovitis after treatment with alendronate and responded to its withdrawal. [ncbi.nlm.nih.gov]
Entire Body System
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Edema of the Hand
At week 4, before the 3rd infusion, he presented with inflammatory arthralgia, synovitis of proximal interphalangeal, wrist and ankle joints, and edema of both hands and forearms. [ncbi.nlm.nih.gov]
[…] in both hands in patient with central cord injury]. 38 Carbonero Martinez E...Ruiz Villaverde G 31186097 2019 5 Predictive factors associated with the therapeutic response in patients with polymyalgia rheumatica and remitting seronegative symmetrical [malacards.org]
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Wheelchair Bound
On evaluation, he was wheelchair bound and completely dependent for all activities of daily living. Evaluation revealed negative serological testing and plain film imaging. [ncbi.nlm.nih.gov]
Musculoskeletal
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Synovial Disorder
The role of hip arthroscopy in the treatment of synovial disorders and loose bodies. Clin Orthop Relat Res 2003;406:48-59. 9. Devaney K, Vinh TN, Sweet DE. Synovial hemangioma: A report of 20 cases with differential diagnostic considerations. [ijpmonline.org]
Arthroscopic treatment of synovial disorders in the shoulder, elbow, and ankle. J Knee Surg 2002;15(1):57-9. [ Links ] 45. Chiffolot X, Ehlinger M, Bonnomet F, Kempf JF. [scielo.br]
Neurologic
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Personality Change
Paired t-tests were used to determine within person change in outcome measures and Spearman's correlation coefficients were used to determine the correlation between change in pain and change in the DCE parameters. [ncbi.nlm.nih.gov]
Workup
Preoperative workup for infection and intraoperative cultures taken at the time of revision surgery were negative for infection. [healio.com]
Workup Laboratory Studies The following studies may be indicated in transient synovitis (TS): CBC count: The white blood cell (WBC) count may be slightly elevated. [emedicine.medscape.com]
Serologic workup performed showed a negative rheumatoid factor, a white blood cell count of 6000 cells/mm3, a C-reactive protein of 0.6 mg/L, and a sedimentation rate of 15 mm in the first hour. [ncbi.nlm.nih.gov]
Septic arthritis workup. Medscape Reference. Available online at . Accessed 9/9/2016. Sofronescu, A. (Updated 2016 April 13). Joint fluid interpretation. Medscape Reference. Available online at . Accessed 9/9/2016. Fisher, M. and Genzen, J. R. [labtestsonline.org]
Treatment
We present a patient who developed polyarticular synovitis after treatment with alendronate and responded to its withdrawal. [ncbi.nlm.nih.gov]
Prognosis
Although the exact aetiology is not clear, yet it responds dramatically to low doses of steroids with excellent prognosis unlike RA and PMR. [ncbi.nlm.nih.gov]
Links: clinical features investigations differential diagnosis management prognosis [gpnotebook.co.uk]
Etiology
The most affected joint from bleeding is the knee whatever the etiology is. Repeated hemarthrosis may produce significant structural alteration of joints leading to chronic osteoarthritis. [ncbi.nlm.nih.gov]
Some have suggested a viral etiology (e.g. related to Parvovirus B-19 and /or Herpes simplex virus 6 infections while others have proposed a post-traumatic etiology with subsequent development of chemical synovitis. [radiopaedia.org]
Epidemiology
Author information 1 Arthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, Faculty of Medical and Human Sciences, Manchester Academic Health Science Centre, University of Manchester, Stopford Building, Oxford Road, Manchester [ncbi.nlm.nih.gov]
[…] foot M67.98 - Unspecified disorder of synovium and tendon, other site M67.99 - Unspecified disorder of synovium and tendon, multiple sites Transient Synovitis ICD-9 727.9 Unspecified disorder of synovium, tendon and bursa Transient Synovitis Etiology / Epidemiology [eorif.com]
Introduction Overview inflammation of the synovium and a common cause of hip pain in pediatric patients that must be differentiated from septic arthritis of the hip treatment is usually anti-inflammatories and supportive measures given self-limiting nature Epidemiology [orthobullets.com]
Pathophysiology
[…] risk factors the exact cause of transient synovitis is largely unknown, however, may be related to viral infection (upper respiratory) bacterial infection ( poststreptococcal toxic synovitis ) trauma higher interferon concentration allergic reaction Pathophysiology [orthobullets.com]
Clinical and pathophysiologic relevance of autoantibodies in rheumatoid arthritis. Adv Rheumatol. 2019;59(1):2. doi:10.1186/s42358-018-0042-8 Brasington RD. Rheumatology (Sixth Edition); 85 - Clinical features of rheumatoid arthritis. 2014. [verywellhealth.com]
Also, the study of enthesitis pathophysiology is limited by the difficulty to obtaining biopsies from the enthesis due to potential adverse effects. [frontiersin.org]
Download citation Published: 02 February 2017 DOI: Keywords Osteoarthritis Synovitis Pathophysiology Epidemiology Imaging Treatment [arthritis-research.biomedcentral.com]
Prevention
Regular factor treatment will help prevent further bleeding. This will give the synovial membrane a chance to return to normal. Oral steroids. These are drugs that reduce inflammation. [hog.org]
How do I prevent knee synovitis? The main way to prevent knee synovitis symptoms is to protect your knees from injury. Even with the most preparation and caution, injuries happen. [drburkeortho.com]
[…] en Indications: For the treatment of CRD and pasteurellosis; synovitis in turkey. sl Če je vse pod nadzorom, bom zunaj en Indications: Treatment and prevention of respiratory and gastrointestinal diseases caused by organism sensitive to doxycycline: broilers [sl.glosbe.com]
CONCLUSIONS: Treatment with CS had a sustained beneficial effect, preventing synovitis onset or reducing its presence as well as reducing KOA symptoms. ACT ameliorated clinical symptoms but had no effect on inflammation. [ncbi.nlm.nih.gov]