Confluent small alopecic patches of the parietal area are present on an erythematous scalp (a). [ncbi.nlm.nih.gov]

Patients often present with other mucocutaneous symptoms of secondary syphilis. [escholarship.org]

• Unsafe Sexual Practices

  Safer-sex messages should include reducing the number of sexual partners; knowing the health status and HIV infection status of partners; avoiding unsafe sexual practices, not just for HIV, but for all STDs; and using barrier protection methods such as [hivinsite.ucsf.edu]

• Pallor

  Given the pustules here, would treat for Staph (not Strep) Discoid Lupus Discoid Lupus (alone, or as a component of SLE) Red papule or plaque, spreads with peripheral hyperpigmentation and central pallor, atrophy, or scarring. [diagnosisdude.com]

• Jaundice

  The fetal stigmata seen before the age of 2 years include eruptions characteristic of secondary syphilis, such as maculopapular rash and desquamating erythema of the palms and soles; hepatosplenomegaly; and jaundice. [dartmouth.edu]

  Yellowing of the skin or the whites of the eyes (jaundice). Late congenital syphilis is rare. It can cause symptoms similar to neurosyphilis in an adult. [patient.info]

• Blurred Vision

  Brain involvement (neurosyphilis) may cause headaches, dizziness, blurred vision, mental disturbances, paralysis and dementia (general paresis). This occurs 10–30 years after infection. [dermnetnz.org]

  Initial symptoms may include headache, neck stiffness, dizziness, behavioral abnormalities, poor concentration, memory loss, lassitude, insomnia, and blurred vision. [merckmanuals.com]

• Alopecia

  A case of syphilitic alopecia on the legs of young man is described. Both positive serologic tests and the clinical response to treatment with penicillin suggest that this alopecia was due to syphilis. [ncbi.nlm.nih.gov]

  Conditions that mimic moth-eaten alopecia include other localized and non-cicatricial alopecias, such as alopecia areata, alopecia neoplastica, tinea capitis, and trichotillomania. [escholarship.org]

  Syphilitic alopecia can closely resemble alopecia areata both clinically and histopathologically. [academic.oup.com]

• Chancre

  Sometimes, multiple chancres may be present. The chancre contains the infectious bacteria and while the sore is present, the condition is highly contagious. Any contact with the chancre can spread the infection. [medicinenet.com]

  Secondary syphilis is a systemic disease caused by the bacteria Treponema pallidum, which is transmitted by direct contact with a syphilis sore called a chancre on the genitals, lips, or in the mouth. [thinninghair.com]

  Primary syphilis manifests with a painless chancre ( primary lesion ), typically on the genitals. Secondary syphilis is characterized by a polymorphic, maculopapular rash that also appears on the palms and soles. [amboss.com]

  The sore is known as a chancre and this phase is known as primary syphilis. Widespread rash and 'flu-like symptoms appear next (secondary syphilis). [dermnetnz.org]

  Symptoms typically begin 6 to 12 wk after the chancre appears; about 25% of patients still have a chancre. Fever, loss of appetite, nausea, and fatigue are common. [merckmanuals.com]

• Skin Rash

  If you do not treat it, syphilis usually causes a non-itchy skin rash, often on your hands and feet. Many people do not notice symptoms for years. Symptoms can go away and come back. [icdlist.com]

  Most often in the case of secondary syphilis such an element of the skin rash occurs as syphilitic roseola or spotted syphilide. This element of the rash is located in the surface layers of the skin. It has a pale pink or deep pink tint. [en.medicine-worlds.com]

  When an associated skin rash or lymphadenopathy is present, the diagnosis of syphilis may be suggested and confirmed by positive serology test results. [mdedge.com]

  Read more » Syphilis Complications After Starting Treatment for HIV ...later with possible signs of skin rash, ulcers in the mouth or genitals, warts on the area around the anus or mouth, patchy hair loss, and possibly fever, fatigue, weight loss, and [thebody.com]

  Secondary Stage During the secondary stage, you may have skin rashes and/or mucous membrane lesions. Mucous membrane lesions are sores in your mouth, vagina, or anus. This stage usually starts with a rash on one or more areas of your body. [cdc.gov]

• Skin Disease

  Provides detailed discussions of metabolic, systemic, allergic, infectious, and inflammatory skin diseases as well as cutaneous neoplasms giving you well-rounded, comprehensive coverage.. [books.google.com]

  Authors: Barth J, Löser C Abstract Johann Heinrich Rille, also characterized as a renowned nestor of German-speaking dermatovenereology, was named as extraordinary professor for syphilis and skin diseases in Leipzig in 1902, the second oldest university [medworm.com]

  Tricotillomania SCARRING ALOPECIA (Skin Disease Noted) Tinea Capitus Tinea Capitus: In developed countries only occurs in children. requires systemic therapy. Tinea Capitus: annular lesion with leading edge is give-away. [diagnosisdude.com]

• Dermatitis

  Seborrheic Dermatitis Seb Derm: Red, greasy patches at hairline, may extend down face Seborrheic Dermatitis: If only at hairline, may mimic Psoriasis Psoriasis Reddish component looks like Seb Derm, but the white/silver scales are a give-away for Psoriasis [diagnosisdude.com]

  Seborrhoeic Dermatitis Although the cause of seborrhoeic dermatitis is unknown, we do know that there are two basic types of the disease. One occurs in newborns and babies, and the other is commonly found in middle-aged adults. [blackhairmedicalexpert.com]

  DERMATOHISTOPATHOLOGY: Spongiotic dermatitis with chronic perifolliculitis and reactive changes. Periodic acid-Schiff (PAS) with diastase stain showed no microorganisms. Immunoperoxidase stains were negative for spirochetes. [aocd-grandrounds.org]

  The minoxidil 5% solution has not been shown to be consistently more effective than the 2% solution, and patients using the higher concentration had more adverse effects, including allergic contact dermatitis, dryness, and itching. 16 These typically [aafp.org]

  […] commonly, tuberculosis, chancroid Anal ulcers : genital herpes, anal fissure, bacterial infections, trauma, inflammatory bowel disease Mouth ulcers : herpes simplex (cold sore), aphthous ulcers, trauma Rash Drug eruption Pityriasis rosea Psoriasis Eczema / dermatitis [dermnetnz.org]

• Chlamydia

  The grants, totaling $41.6 million over five years, will support collaborative, multidisciplinary research on the bacteria that cause syphilis, gonorrhea and chlamydia. [medworm.com]

  Patients diagnosed with syphilis should also be screened for other sexually transmitted diseases ( HIV, gonorrhea, chlamydia )! References: [3] [11] [6] [12] [13] [14] Treatment Penicillin is the drug of choice for treatment of syphilis! [amboss.com]

  A GUM clinic will take small samples (swabs) and blood tests to exclude other STIs such as chlamydia, gonorrhoea and HIV. [patient.info]

  For the patient with multiple sex partners or with a partner who in turn has multiple partners, screening for STDs such as syphilis, gonorrhea, and Chlamydia should be done at least annually, and twice yearly if risk is higher.(47) MSM or other persons [hivinsite.ucsf.edu]

Treatment The preparation, dosage, and duration of treatment vary, depending on the stage of syphilis, HIV status of the patient, and presence of neurosyphilis [23, 24, 25, 26]. [escholarship.org]

Natural 500ML Herbal Hair Shampoo Black Rose Moisturizing Hair Treatment Cream HMG-18. [hieratic.eu]

Both positive serologic tests and the clinical response to treatment with penicillin suggest that this alopecia was due to syphilis. [ncbi.nlm.nih.gov]

[…] of HIV in Industrialized and Middle Income CountriesŠAdults Adolescents and Pediatric 1310 Chapter 115 Guidelines for the Treatment of HIV and AIDS in ResourceLimited Countries 1328 Chapter 116 Guidelines for Prevention of Perinatal HIV Infection 1345 [books.google.com]

[…] favorable prognosis for patients diagnosed with either primary or secondary syphilis 20% of untreated patients with tertiary syphilis die of the disease prognosis for tertiary syphilis depends on the extent of scarring and tissue damage with adequate [medbullets.com]

Patient Education National Alopecia Areata Foundation: www.naaf.org Prognosis Androgenic alopecia : Prognosis depends on response to treatment. AA : often regrows within 1 year even without treatment. [unboundmedicine.com]

With penicillin administration, hair of the legs, scalp, and eyebrows started to grow; the hair was fully regrown within 6 months, which suggests good prognosis with treatment instigation for syphilitic alopecia of all areas. [mdedge.com]

The more profuse the eruption the better is the prognosis. The severe type (Oroya): The only skin manifestations are mild skin lesion due to insect bite at the site of inoculation. [drmhijazy.com]

[…] squaric acid ( Table 2 5 – 18 ). 7 Overall, 34 to 50 percent of patients with alopecia areata will recover within one year; this number is as high as 80 percent in patients with one or two patches. 6 The more severe the disease at onset, the worse the prognosis [aafp.org]

Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]

McKee's Pathology of the Skin is the most complete, in-depth resource on dermatopathology, covering etiology, pathogenesis, disease mechanisms, and recent genetic, molecular, and basic science data. Drs. J. [books.google.com]

Treatments all focus on symptom management rather than etiology. [unboundmedicine.com]

Clinically, diffuse syphilitic alopecia, as a rule, does not differ from symptomatic hair loss of a different etiology, therefore, in all patients with a sudden diffuse alopecia of unknown etiology, it is recommended to investigate serological responses [en.medicine-guidebook.com]

Etiology Treponema bacteria (particularly during stages I/II) are highly contagious! Sexual contact with a partner who suffers from active syphilis will lead to infection in 30% of cases! [amboss.com]

Venereal Diseases; Milica Marković ; City Institute for Skin and Venereal Diseases Džordža Vašingtona 17 11000 Belgrade Serbia Dubravka Salemović ; Institute for Infectious and Tropical Diseases, Clinical Centre of Serbia Sandra Šipetić ; Institute of Epidemiology [hrcak.srce.hr]

Epidemiology References: [1] [2] Epidemiological data refers to the US, unless otherwise specified. Etiology Treponema bacteria (particularly during stages I/II) are highly contagious! [amboss.com]

Reexamining syphilis: an update on epidemiology, clinical manifestations, and management. Annals of Pharmacotherapy 2008; 42: 226-236. [PubMed] 13. Jordaan HF, Louw M. [escholarship.org]

Epidemiology Epidemiologic studies demonstrate that history of an STD, including syphilis, is associated with an increased risk of HIV disease among both gay men (7,9) and heterosexuals (8) because sexual behaviors that increase the risk of acquiring [hivinsite.ucsf.edu]

Introduction Classification Treponema pallidum spirochete Epidemiology demographics most common during years of peak sexual activity most new cases occur in men and women aged 20-29 years recent rise in syphilis cases among men who have sex with men [medbullets.com]

References: [3] [4] Pathophysiology Clinical features Primary syphilis Primary lesion ( chancre ) Typically starts out as a solitary, raised papule (usually on the genitals) Evolves into painle ss, firm ulcer with indurated borde rs and smooth base Resolves [amboss.com]

Commonly Associated Conditions See “Etiology and Pathophysiology.” [unboundmedicine.com]

Encyclopedia) RPR test (Medical Encyclopedia) Syphilis (Centers for Disease Control and Prevention) Syphilis - primary (Medical Encyclopedia) Syphilis and MSM (Men Who Have Sex with Men) (Centers for Disease Control and Prevention) VDRL test (Medical [icdlist.com]

Chapter 69 Surrogate Markers of Antiretroviral Efficacy 826 Overcoming Barriers to Providing ARV Therapy in ResourceLimited Settings 831 Chapter 71 Antiretroviral Drugs for HIV Prevention 836 Chapter 72 Acute HIV Infection 843 Chapter 73 Opportunistic [books.google.com]

It is unclear, however, whether repeated doses or larger doses of benzathine penicillin would prevent neurosyphilis [25]. [escholarship.org]

Adequate therapy of the infected mother before the sixteenth week of gestation usually prevents infection of the fetus. [dartmouth.edu]

Asymptomatic ( latent ) syphilis should be treated to prevent occurrence of late complications (tertiary syphilis). [dermnetnz.org]