Edit concept Question Editor Create issue ticket

Syphilitic Aortitis

Aortitis due to Syphilis


Presentation

  • We present a case of syphilitic aortitis that presented as a mediastinal mass and report the use of polymerase chain reaction for Treponema pallidum to diagnose syphilitic aortic disease.[ncbi.nlm.nih.gov]
Fatigue
  • Symptoms of aortitis In patients with aortitis following symptoms may occur: weakness, fever, weight loss, skin rash, vascular insufficiency, sweating especially at night, joint pain and fatigue.[remedyland.com]
  • Headaches Pain in the jaw or tongue muscles when eating or talking Tenderness of the scalp over the temples Loss of vision Double vision Fever Unexplained weight loss Dizziness Difficulty with coordination Difficulty with balance Night sweats Joint pain Fatigue[cedars-sinai.edu]
  • The average time from disease exposure to cardiovascular event is between 10 and 40 years. 1,3 Nonspecific symptoms such as midscapular pain, atypical chest pain, and progressive fatigue are the most commonly reported physical symptoms prior to an often[consultant360.com]
  • Other symptoms may include fatigue, arm or leg weakness or pain with use, lightheadedness, dizziness, fainting and headaches.[vasculitisfoundation.org]
  • The disease begins with the general symptoms: increased fatigue, subfebrile temperature; some patients are disturbed by night sweats and mialgiya; then there are severe headaches; rise in arterial pressure is often observed.[bigmed.info]
Prostitute
  • Diagnosis Physical Examination Syphilitic aortitis can cause de Musset's sign , [1] a bobbing of the head that de Musset first noted in Parisian prostitutes.[wikidoc.org]
Prostitute
  • Diagnosis Physical Examination Syphilitic aortitis can cause de Musset's sign , [1] a bobbing of the head that de Musset first noted in Parisian prostitutes.[wikidoc.org]
Recurrent Respiratory Infections
  • Recurrent respiratory infections are common as a result of pressure on the trachea and bronchi.[drbeen.com]
Diastolic Murmur
  • murmur Characteristic loud "tambour like" (booming and ringing quality like a drum) second sound is the most significant sign of syphilitic aortitis Complications Aortic aneurysm, aortic regurgitation and coronary ostia stenosis Laboratory Non treponemal[pathologyoutlines.com]
  • On examination, early diastolic murmur of grade 2 in Erbs area. Routine investigation was normal. VDRL and TPHA were positive. HIV and connective tissue profile was normal.[austinpublishinggroup.com]
  • On physical examination, the only abnormal finding was a grade 2/6 high-pitched diastolic murmur. Coro-nary risk factor was not detected from biochemical results, but both the TPHA and FTA-ABS test were positive. Copyright 1991, Igaku-Shoin Ltd.[webview.isho.jp]
Forgetful
  • Cardiovascular syphilis is still present nowadays and it is important not to forget the “great imitator” in the event of its characteristic symptoms. KEY WORDS: Syphilis – Cardiovascular complication – Aortitis – Treponema Pallidum[minervamedica.it]

Workup

  • Each disease entity is introduced by an illustrative case presentation and is followed by a detailed topic review including clinical features, laboratory and imaging workup, treatment and prognosis, clinical pearls, discussion of differential diagnoses[books.google.ro]
Mediastinal Mass
  • The case is unusual as the syphilitic aortitis caused a mediastinal mass without affecting the lumen of the aorta.[ncbi.nlm.nih.gov]
Pericardial Effusion
  • In addition, it also displayed mild aortic regurgitation, ascending aorta dilatation above the sinotubular junction (41mm), and mild to moderate anterior pericardial effusion (10mm thick) without signs suggestive of increased intrapericardial pressure[sbcsc2017.com.br]
  • In addition, it also displayed mild aortic regurgitation, ascending aorta dilatation above the sinotubular junction (41 mm), and mild to moderate anterior pericardial effusion (10 mm thick) without signs suggestive of increased intrapericardial pressure[bjid.elsevier.es]
Abnormal ECG
  • Physical examination showed no significant abnormalities. ECG evidenced signs of atrial and ventricular overload and no signs of ischemia.[sbcsc2017.com.br]

Treatment

  • This case highlights the usefulness of FDG PET/CT for the assessment of disease extent and treatment response in patients with syphilitic aortitis.[ncbi.nlm.nih.gov]
  • Mello Syphilitic aortitis: diagnosis and treatment. Case report Rev Bras Cir Cardiovasc, 25 (2010), pp. 415-418 [9] L.V. Stamm Syphilis: antibiotic treatment and resistance [10] B.P.[bjid.elsevier.es]
  • Treatment for tertiary syphilis was prescribed with benzathine penicillin G 2.4 million units once weekly for three weeks. Lumbar puncture before treatment showed no central nervous system involvement. Conclusions.[sbcsc2017.com.br]

Prognosis

  • Each disease entity is introduced by an illustrative case presentation and is followed by a detailed topic review including clinical features, laboratory and imaging workup, treatment and prognosis, clinical pearls, discussion of differential diagnoses[books.google.ro]
  • […] depends on age, sex, occupation, stage of infection, site and extent of lesion, nature of lesion (progressive or stationary), response to treatment, cardiac efficiency, presence of complications The prognosis is better in patients with uncomplicated[pathologyoutlines.com]
  • Treatment and prognosis High-dose antibiotics and resection of enlarging aneurysm. History and etymology The term "lues" is an old name for syphilis, derived from Latin lues for "filth".[radiopaedia.org]
  • Prognosis in these cases is an extremely difficult problem.[stdpioneer.org]
  • What’s the prognosis? The outlook for patients with aortitis depends somewhat on the underlying cause. Infectious aortitis has a particularly high mortality rate.[vasculitisfoundation.org]

Etiology

  • Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology.[icd10coded.com]
  • ) English ICPC2ICD10ENG MTHU007458 L3511841 no S4137884 Y aortitis; Doehle-Heller (etiology) English ICPC2ICD10ENG MTHU023718 L3513399 no S4138034 Y Doehle-Heller (etiology) English ICPC2ICD10ENG MTHU023721 L3518383 no S4138067 Y Doehle-Heller; aortitis[doctor.am]
  • Italian Aortite sifilitica English Doehle-Heller (etiology) Last Update: 2014-12-09 Usage Frequency: 1 Warning: This alignment may be wrong. Please delete it you feel so.[mymemory.translated.net]
  • Pathogenesis, symptoms and signs, diagnosis, and treatment differ by etiology. However, the general principle for treatment is to treat the underlying disorder. Resources In This Article[merckmanuals.com]
  • Pathology Etiology infectious syphilitic aortitis tuberculous aortitis pyogenic aortitis: especially Salmonella infection aortitis due to HIV infected (mycotic) aortic aneurysm non-infectious giant cell arteritis Takayasu arteritis other rheumatologic[radiopaedia.org]

Epidemiology

  • The Changing Epidemiology of Syphilis. Sexually Transmitted Diseases. 2005, 32:S4-S10[ivyunion.org]
  • It is updated with the most recent basic clinical research, epidemiological findings, medical, surgical and endovascular therapies of the aorta.[books.google.com]
  • Syphilis: review with emphasis on clinical, epidemiologic, and some biologic features. Clin Microbiol Rev. 1999;12(2):187-209. Larsen SA, Creighton ET. Rapid plasma reagin (RPR) 18-mm circle card test.[consultant360.com]
  • Pusey WA: The history and epidemiology of syphilis. Springfield, Thomas Books, 1933. Venereal Disease Program. Syphilis a synopsis. Atlanta, US Department of Health, Education, and Welfare, 1968. Lukehart SA: Syphilis. Harrison’s Online.[karger.com]
  • […] grading and staging of metastasis, the clonal origin of cancer, the growth of cancers, the molecular genetics of cancers, viruses and human cencer, chemical carcinogenesis, physical carcinogenesis, tumor immunology, systemic effects of cancer on the host, epidemiology[departamentmorfologie.ro]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology Inflammatory involvement of tertiary syphilis begins at the adventitia of the aortic arch which progressively causes obliterative endarteritis of the vaso vasorum.[wikidoc.org]
  • Definition / general Due to spirochete, Treponema pallidum Rare in developed and developing countries Male:female is 2:1 to 4:1 Affects aortic valve and ascending aorta Pathophysiology Treponema pallida reach cardiovascular system a short time after initial[pathologyoutlines.com]
  • 以下为句子列表: 英文: A particularly exciting dimension of cerebral ischemia research in the 1990s is the growing contribution of molecular biology, to both our understanding of the pathophysiology of ischemic injury and the construction of novel therapeutic approaches[dict.bioon.com]
  • Which pathophysiologic conditions are seen with transudate and exudate fluid? 2) What is the definition of ulceration and why can’t it occur in the brain? Thanks in advance![pathology.edublogs.org]

Prevention

  • NIH: National Institute of Allergy and Infectious Diseases Condom Fact Sheet in Brief (Centers for Disease Control and Prevention) Congenital syphilis CSF-VDRL test FTA-ABS test Neurosyphilis RPR test Syphilis (Centers for Disease Control and Prevention[icdlist.com]
  • Rapidly find the answers you need with separate sections on diseases and disorders, differential diagnosis, clinical algorithms, laboratory results, and clinical preventive services, plus an at-a-glance format that uses cross-references, outlines, bullets[books.google.ro]
  • Preventive Services Task Force. Screening for syphilis infection: recommendation statement. Ann Fam Med. 2004, 2:362 Zehr KJ, Orszulak TA, Mullany CJ, et al. Surgery for aneurysms of the aortic root: a 30-year experience.[ivyunion.org]
  • Centers for Disease Control and Prevention (CDC). Primary and secondary syphilis—United States, 2003–2004. MMWR Morb Mortal Wkly Rep. 2006;55(10):269–273. ... 2. Centers for Disease Control and Prevention.[aafp.org]

Ask Question

5000 Characters left Format the text using: # Heading, **bold**, _italic_. HTML code is not allowed.
By publishing this question you agree to the TOS and Privacy policy.
• Use a precise title for your question.
• Ask a specific question and provide age, sex, symptoms, type and duration of treatment.
• Respect your own and other people's privacy, never post full names or contact information.
• Inappropriate questions will be deleted.
• In urgent cases contact a physician, visit a hospital or call an emergency service!