We present a case of syphilitic aortitis that presented as a mediastinal mass and report the use of polymerase chain reaction for Treponema pallidum to diagnose syphilitic aortic disease. [ncbi.nlm.nih.gov]

• Fatigue

  Symptoms of aortitis In patients with aortitis following symptoms may occur: weakness, fever, weight loss, skin rash, vascular insufficiency, sweating especially at night, joint pain and fatigue. [remedyland.com]

  Headaches Pain in the jaw or tongue muscles when eating or talking Tenderness of the scalp over the temples Loss of vision Double vision Fever Unexplained weight loss Dizziness Difficulty with coordination Difficulty with balance Night sweats Joint pain Fatigue [cedars-sinai.edu]

  Other symptoms may include fatigue, arm or leg weakness or pain with use, lightheadedness, dizziness, fainting and headaches. [vasculitisfoundation.org]

  The average time from disease exposure to cardiovascular event is between 10 and 40 years. 1,3 Nonspecific symptoms such as midscapular pain, atypical chest pain, and progressive fatigue are the most commonly reported physical symptoms prior to an often [consultant360.com]

  The disease begins with the general symptoms: increased fatigue, subfebrile temperature; some patients are disturbed by night sweats and mialgiya; then there are severe headaches; rise in arterial pressure is often observed. [bigmed.info]

• Swelling

  Sometimes it causes swelling in nearby lymph nodes. If you do not treat it, syphilis usually causes a non-itchy skin rash, often on your hands and feet. Many people do not notice symptoms for years. Symptoms can go away and come back. [icdlist.com]

  Semestrul I General Pathology 1.a Cell injury: atrophy, hypertrophy, hyperplasia, metaplasia, dysplasia, calcification, hyaline, hydropic swelling, oxidative stress, intracellular storage, morphology of necrosis, apoptosis, ischemia/reperfusion injury [departamentmorfologie.ro]

  At rheumatism in all layers of an aorta find the centers of disorganization of fabric with consecutive development of mucoid hypostasis, fibrinoid swelling and transition to a granulomatosis and a sclerosis. [bigmed.info]

• Reiter Syndrome

  syndrome ankylosing spondylitis Cogan syndrome chronic periaortitis idiopathic aortitis radiation-induced aortitis IgG4-related cardiovascular disease References Related Radiopaedia articles Aortic pathology acute aortic syndrome aortic dissection Stanford [radiopaedia.org]

• Hoarseness

  A 47 year old man presented with hoarseness and chest pain found to be due to proliferative syphilitic aortitis. The case is unusual as the syphilitic aortitis caused a mediastinal mass without affecting the lumen of the aorta. [ncbi.nlm.nih.gov]

  Note: There are associated pressure symptoms of dysphagia, hoarseness, brassy cough, back pain (vertebral erosion is characteristic) and occasionally rupture of the aneurysm. [drbeen.com]

  Abstract A 47 year old man presented with hoarseness and chest pain found to be due to proliferative syphilitic aortitis. The case is unusual as the syphilitic aortitis caused a mediastinal mass without affecting the lumen of the aorta. [thorax.bmj.com]

  Case report A 55-year-old male was admitted to the hospital complaining “progressive hoarseness for 3 months”. He denied symptoms, including chest pain, cough, dry cough, and dyspnea. [springerplus.springeropen.com]

  […] artery; causing an angina, or severe heart attack Weakening of aortic valves with scarring; causing heart failure and aortic regurgitation Aortic walls are damaged/destroyed leading to aneurysm formation Other symptoms include: Dry cough, back pain, hoarseness [dovemed.com]

• Regurgitation

  It is important to note that syphilis is one of the causes of coronary ostial stenosis in young adults associated with aortic regurgitation. [ncbi.nlm.nih.gov]

• Failure to Thrive

  Fred Ferri’s popular "5 books in 1" format provides quick guidance on menorrhagia, Failure to Thrive (FTT), Cogan’s syndrome, and much more. [books.google.ro]

• Chest Pain

  A 47 year old man presented with hoarseness and chest pain found to be due to proliferative syphilitic aortitis. The case is unusual as the syphilitic aortitis caused a mediastinal mass without affecting the lumen of the aorta. [ncbi.nlm.nih.gov]

  Dyspnea was increasing steadily and currently had dyspnea on moderate effort, accompanied by non-characteristic chest pain. This pain has drawn attention from family members, who opted for medical advice. [rbccv.org.br]

  Abstract A 47 year old man presented with hoarseness and chest pain found to be due to proliferative syphilitic aortitis. The case is unusual as the syphilitic aortitis caused a mediastinal mass without affecting the lumen of the aorta. [thorax.bmj.com]

  We report a case of gross ascending aortic anuersym who presented with Dyspnoea NYHA class III and chest pain since six months. Options of surgery were discussed with patient’s relatives. [austinpublishinggroup.com]

• Diastolic Murmur

  […] hypertension in young Palpable and visible pulsation in suprasternal notch Diagnosis Ejection murmur and aortic diastolic murmur Characteristic loud "tambour like" (booming and ringing quality like a drum) second sound is the most significant sign of [pathologyoutlines.com]

  On examination, early diastolic murmur of grade 2 in Erbs area. Routine investigation was normal. VDRL and TPHA were positive. HIV and connective tissue profile was normal. [austinpublishinggroup.com]

  On physical examination, the only abnormal finding was a grade 2/6 high-pitched diastolic murmur. Coro-nary risk factor was not detected from biochemical results, but both the TPHA and FTA-ABS test were positive. Copyright © 1991, Igaku-Shoin Ltd. [webview.isho.jp]

• Suggestibility

  A repeated FDG PET/CT after antibiotic therapy showed a markedly reduced uptake in the aortic wall, suggesting resolution of the infection according to clinical and serological data. [ncbi.nlm.nih.gov]

  Positive complement fixations in patients suffering with syphilis for a period of about fifteen years or longer suggest the probability, at least, of histological luetic changes in the aorta in 80 to 90 per cent of the cases. 60 per cent of these die [jem.rupress.org]

  It was then suggested the diagnosis described. Other diagnoses were considered - the giant cell arteritis (or temporal arteritis) and Takayasu's arteritis - due to the involvement of the aorta by both diseases. [rbccv.org.br]

  A 12-lead electrocardiogram and blood tests on arrival suggested AMI, and echocardiography showed moderate AR. Emergency coronary angiography showed bilateral coronary ostial stenosis. [kumamoto.hosp.go.jp]

  Access full-color images and 65 online-only topics at Expert Consult, as well as online-only contents including EBMs, Suggested Reading, Patient Teaching Guides, and additional algorithms. [books.google.ro]

• Meningism

  Congenital syphilis CSF-VDRL test FTA-ABS test Neurosyphilis RPR test Syphilis (Centers for Disease Control and Prevention) Syphilis - primary Syphilis and MSM (Men Who Have Sex with Men) (Centers for Disease Control and Prevention) Syphilitic aseptic meningitis [icdlist.com]

  […] endocarditis A52.04 Syphilitic cerebral arteritis A52.05 Other cerebrovascular syphilis A52.06 Other syphilitic heart involvement A52.09 Other cardiovascular syphilis A52.1 Symptomatic neurosyphilis A52.12 Other cerebrospinal syphilis A52.13 Late syphilitic meningitis [icd10data.com]

  […] cardiovascular syphilis A52.1 Symptomatic neurosyphilis A52.10 Symptomatic neurosyphilis, unspecified A52.11 Tabes dorsalis Inclusion term(s): Locomotor ataxia (progressive) Tabetic neurosyphilis A52.12 Other cerebrospinal syphilis A52.13 Late syphilitic meningitis [icd10coded.com]

  […] neoplasms of the skin: benign nevus, atypical nevus, malignant melanoma, keratosis, basal cell carcinoma, squamous cell carcinoma, Merkel cell carcinoma, HIV infection and the skin. 2.n The nervous system: cerebral hematomas, vascular malformations, meningitis [departamentmorfologie.ro]

  Acute syphilitic meningitis: its occurrence after clinical and serologic cure of secondary syphilis with penicillin. G. Arch Neurol 1986;43:137-8. Jorgensen J, Tikjob G, Weismann K. [cdc.gov]

Each disease entity is introduced by an illustrative case presentation and is followed by a detailed topic review including clinical features, laboratory and imaging workup, treatment and prognosis, clinical pearls, discussion of differential diagnoses [books.google.ro]

• Mediastinal Mass

  The case is unusual as the syphilitic aortitis caused a mediastinal mass without affecting the lumen of the aorta. [ncbi.nlm.nih.gov]

• Mural Thrombus

  thrombus causing the trachea and esophagus to shift to the right. [ncbi.nlm.nih.gov]

  T 1 -weighted images also revealed evidence of mural thrombus in the superior aspect of the aneurysm, beyond the left subclavian artery (arrow in Panel B). [nejm.org]

  thrombus of the abdominal aorta: Mural thrombus of the abdominal aorta, Macro, autopsy (71432) Mural thrombus with calcification: Mural thrombus with calcification, Macro, autopsy (71433) Pictures Colon, early gangrene: Colon, early gangrene, Macro, [atlases.muni.cz]

• Treponema Pallidum

  The serological positivity for Treponema pallidum and the histopathological study allowed the currently rare diagnosis of Ascending Aortic Aneurysm by Tertiary Syphilis. [ncbi.nlm.nih.gov]

  Serologic immunofluorescence studies revealed the presence of Treponema pallidum antigen, confirming the clinical suspicion of syphilitic aortitis and aneurysm. [nejm.org]

  KEY WORDS: Syphilis – Cardiovascular complication – Aortitis – Treponema Pallidum [minervamedica.it]

This case highlights the usefulness of FDG PET/CT for the assessment of disease extent and treatment response in patients with syphilitic aortitis. [ncbi.nlm.nih.gov]

Mello Syphilitic aortitis: diagnosis and treatment. Case report Rev Bras Cir Cardiovasc, 25 (2010), pp. 415-418 [9] L.V. Stamm Syphilis: antibiotic treatment and resistance [10] B.P. [bjid.elsevier.es]

Treatment of severe syphilitic aortitis is surgery. [rbccv.org.br]

Treatment for tertiary syphilis was prescribed with benzathine penicillin G 2.4 million units once weekly for three weeks. Lumbar puncture before treatment showed no central nervous system involvement. Conclusions. [sbcsc2017.com.br]

[…] depends on age, sex, occupation, stage of infection, site and extent of lesion, nature of lesion (progressive or stationary), response to treatment, cardiac efficiency, presence of complications The prognosis is better in patients with uncomplicated [pathologyoutlines.com]

Each disease entity is introduced by an illustrative case presentation and is followed by a detailed topic review including clinical features, laboratory and imaging workup, treatment and prognosis, clinical pearls, discussion of differential diagnoses [books.google.ro]

Treatment and prognosis High-dose antibiotics and resection of enlarging aneurysm. History and etymology The term "lues" is an old name for syphilis, derived from Latin lues for "filth". [radiopaedia.org]

Prognosis in these cases is an extremely difficult problem. [stdpioneer.org]

What’s the prognosis? The outlook for patients with aortitis depends somewhat on the underlying cause. Infectious aortitis has a particularly high mortality rate. [vasculitisfoundation.org]

Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]

Italian Aortite sifilitica English Doehle-Heller (etiology) Last Update: 2014-12-09 Usage Frequency: 1 Warning: This alignment may be wrong. Please delete it you feel so. [mymemory.translated.net]

Pathogenesis, symptoms and signs, diagnosis, and treatment differ by etiology. However, the general principle for treatment is to treat the underlying disorder. Resources In This Article [merckmanuals.com]

Pathology Etiology infectious syphilitic aortitis tuberculous aortitis pyogenic aortitis: especially Salmonella infection aortitis due to HIV infected (mycotic) aortic aneurysm non-infectious giant cell arteritis Takayasu arteritis other rheumatologic [radiopaedia.org]

The Changing Epidemiology of Syphilis. Sexually Transmitted Diseases. 2005, 32:S4-S10 [ivyunion.org]

It is updated with the most recent basic clinical research, epidemiological findings, medical, surgical and endovascular therapies of the aorta. [books.google.com]

Syphilis: review with emphasis on clinical, epidemiologic, and some biologic features. Clin Microbiol Rev. 1999;12(2):187-209. Larsen SA, Creighton ET. Rapid plasma reagin (RPR) 18-mm circle card test. [consultant360.com]

Pusey WA: The history and epidemiology of syphilis. Springfield, Thomas Books, 1933. Venereal Disease Program. Syphilis a synopsis. Atlanta, US Department of Health, Education, and Welfare, 1968. Lukehart SA: Syphilis. Harrison’s Online. [karger.com]

[…] grading and staging of metastasis, the clonal origin of cancer, the growth of cancers, the molecular genetics of cancers, viruses and human cencer, chemical carcinogenesis, physical carcinogenesis, tumor immunology, systemic effects of cancer on the host, epidemiology [departamentmorfologie.ro]

Pathophysiology Inflammatory involvement of tertiary syphilis begins at the adventitia of the aortic arch which progressively causes obliterative endarteritis of the vaso vasorum. [wikidoc.org]

Definition / general Due to spirochete, Treponema pallidum Rare in developed and developing countries Male:female is 2:1 to 4:1 Affects aortic valve and ascending aorta Pathophysiology Treponema pallida reach cardiovascular system a short time after initial [pathologyoutlines.com]

以下为句子列表： 英文: A particularly exciting dimension of cerebral ischemia research in the 1990s is the growing contribution of molecular biology, to both our understanding of the pathophysiology of ischemic injury and the construction of novel therapeutic approaches [dict.bioon.com]

Which pathophysiologic conditions are seen with transudate and exudate fluid? 2) What is the definition of ulceration and why can’t it occur in the brain? Thanks in advance! [pathology.edublogs.org]

Cardiovascular and Thoracic Annals. 2016; 24(2): 198 [Pubmed] | [DOI] 13 Syphilitic aortic aneurysm with a pulmonary lesion: a case report and literature view Wei Li,Xiu-Jun Yin,Hua-Ying Liu,Rong Yang SpringerPlus. 2016; 5(1) [Pubmed] | [DOI] 14 Updates in Pathophysiology [ijpmonline.org]

NIH: National Institute of Allergy and Infectious Diseases Condom Fact Sheet in Brief (Centers for Disease Control and Prevention) Congenital syphilis CSF-VDRL test FTA-ABS test Neurosyphilis RPR test Syphilis (Centers for Disease Control and Prevention [icdlist.com]

Rapidly find the answers you need with separate sections on diseases and disorders, differential diagnosis, clinical algorithms, laboratory results, and clinical preventive services, plus an at-a-glance format that uses cross-references, outlines, bullets [books.google.ro]

The latter speculated that the structural pathology which many of the patients shared resulted in an inability of the aortic valve to appropriately close and prevent the reflux of blood back into the left ventricle. [radiopaedia.org]

Centers for Disease Control and Prevention (CDC). Primary and secondary syphilis—United States, 2003–2004. MMWR Morb Mortal Wkly Rep. 2006;55(10):269–273. ... 2. Centers for Disease Control and Prevention. [aafp.org]