Presentation
Our patient was treated with oral corticosteroids prior to presentation. [healio.com]
The colour vision and visual fields continued to be markedly impaired when she was lost to follow-up 2 months after presentation. Case 2 A 40-year-old homosexual man presented with a painless reduction of vision in his right eye. [nature.com]
ARTICLE IN PRESS a r c h s o c e s p o f t a l m o l. 2 0 1 7;x x x(x x):xxx–xxx ARCHIVOS DE LA SOCIEDAD ESPAÑOLA DE OFTALMOLOGÍA www.elsevier.es/oftalmologia Short communication Syphilitic posterior placoid chorioretinitis as initial presentation of [kundoc.com]
We present an untreated patient with complete spontaneous resolution of ASPPC. [egms.de]
In the series by Pichi and colleagues, subretinal fluid was noted only in patients who had imaging done within the first 2 days of presentation; images from 1 week after presentation and later failed to demonstrate any subretinal fluid[ 10 ]. [joii-journal.springeropen.com]
Skin
- Palmar Erythema
erythema, hair loss) could be interpreted as medication-induced complications. [link.springer.com]
Urogenital
- Urethral Discharge
There was no history of urethral discharge. Over the last 2 weeks he had also developed painful mouth ulcers. There was no history of intravenous drug usage. On examination, visual acuity was 6/60 OD, 6/9 OS. [nature.com]
Workup
A case report illustrates the importance of performing a systemic workup on all patients with posterior uveitis. By Nora Muakkassa, MD, and Lana Rifkin, MD ; edited by Heeral R. Shah, MD, and Jordana G. [retinatoday.com]
The patient’s history and ED workup were notable for MSM, positive rapid plasmin reagin (RPR) and HIV tests and fundus exam consistent with ocular syphilis, specifically uveitis. [westjem.com]
It is important to differentiate fungal and bacterial causes of endophthalmitis and systemic status of the patient including blood cultures and workup, and patient risk factors, such as bacterial septicemia from wound infections, endocarditis, liver abscess [retinalphysician.com]
Treatment
[…] patients remain serofast after treatment with stable titers for life. 33,34 Treatment of patients who are severely allergic to penicillin involves an alternative agent such as the tetracyclines or ceftriaxone. [reviewofoptometry.com]
The standard treatment for neurosyphilis, intravenous penicillin G, was initiated in all patients within 10 to 14 days of presentation. Post-treatment OCT displayed restoration of the ellipsoid and RPE layers in nearly all patients. [healio.com]
With treatment of his neurosyphillis his vision improved from 20/63 to 20/32. [retinagallery.com]
276 1552 Symptomatic Treatment 277 156 Differential Diagnosis 278 1563 Congenital Fibrosis of the Extraocular Muscles 279 Treatment of Specific Types of Nystagmus 283 161 Introduction 284 16211 Etiology 286 16212 Therapeutic Recommendations 287 1622 [books.google.com]
One month after beginning the treatment, LE VA was 1. Discussion The most frequent expression of ocular syphilis is uveitis. [kundoc.com]
Prognosis
Ischemic Visual Loss 235 1335 Orbital Manifestations 236 1343 LargeVessel Vasculitis 237 135 Laboratory Investigations in GCA 238 1352 CReactive Protein 239 1355 Anemia 240 1361 Temporal Artery Biopsy 241 1363 Role of Ultrasound 243 137 Treatment and Prognosis [books.google.com]
Misdiagnosis as AION could lead to steroid therapy without antibiotics, which can worsen prognosis. [e-sciencecentral.org]
Nevertheless, a UK survey of children with toxoplasmic retinochoroiditis found that, overall, the visual prognosis was good. [ 16 ] [patient.info]
Prognosis The prognosis for patients with retinal vasculitis is variable, reflecting the heterogenous nature of this group of disorders. References: Graham E, Spalton DJ, Sanders MD: Immunological investigations in retinal vasculitis. [eophtha.com]
Endogenous endophthalmitis: diagnosis, management, and prognosis. J Ophthalmic Inflamm Infect. 2015;5(1):32. Sugita S, Kamoi K, Ogawa M, Watanabe K, Shimizu N, Mochizuki M. [retinalphysician.com]
Etiology
Pathology Etiology various congenital infections such as 2,3 rubella: ocular rubella cytomegalovirus: ocular cytomegalovirus toxoplasmosis: ocular toxoplasmosis as a ocular manifestation of tuberculosis syphilis : syphilitic posterior placoid chorioretinitis [radiopaedia.org]
274 1541 Myohistological Investigations 275 155 Treatment 276 1552 Symptomatic Treatment 277 156 Differential Diagnosis 278 1563 Congenital Fibrosis of the Extraocular Muscles 279 Treatment of Specific Types of Nystagmus 283 161 Introduction 284 16211 Etiology [books.google.com]
Epidemiology U.S. incidence dropped through 2000 but has risen since with more cases in men having sex with men Etiology Caused by Treponema pallidum, subspecies pallidum, a microaerophilic spirochete that is pathogenic only to humans Clinical features [pathologyoutlines.com]
Anterior uveitis (iritis, iridocyclitis), is primarily due to rheumatologic and idiopathic etiologies with herpes being the most common infectious cause. [westjem.com]
Congenital toxoplasma and cytomegalovirus (CMV) infection are the most common etiologies in this age group. [emedicine.medscape.com]
Epidemiology
Epidemiology U.S. incidence dropped through 2000 but has risen since with more cases in men having sex with men Etiology Caused by Treponema pallidum, subspecies pallidum, a microaerophilic spirochete that is pathogenic only to humans Clinical features [pathologyoutlines.com]
A systematic review of the epidemiologic interactions between classic STD and HIV: how much is really known. Sex Transm Dis. 2001;28:579-597. 18. Sperling L. Syphilitic Alopecia. [westjem.com]
Non-infective causes are also infrequent with few epidemiological data available. [patient.info]
Today, the knowledge of even rare manifestations of the disease and the awareness of its increasing epidemiological relevance remain the key requirement for a correct and rapid diagnosis of Treponema pallidum infections by physicians. [link.springer.com]
JET is a professor of Ophthalmology and Epidemiology. JPD is an associate professor of Ophthalmology. BMB, NJB, and TGL are assistant professors of Ophthalmology. TAO is a Uveitis Fellow. [joii-journal.springeropen.com]
Pathophysiology
The pathophysiology of ASPPC is not completely understood. [joii-journal.springeropen.com]
By better understanding the response to infectious agents, we could learn about our immune system, his defense mechanisms and the pathophysiology of infectious diseases. [egms.de]
The pathophysiology of ASPPC is not well understood, but recent studies of FAF and mfERG findings indicate choroidal and RPE inflammation with significant, often long-lasting, disruption of the photoreceptors. [reviewofoptometry.com]
These include rickettsiosis, Rift Valley fever, dengue fever, and Chikungunya virus. [7] Pathophysiology Chorioretinitis affects the uveal tract, which consists of the iris, ciliary body, and choroid. [emedicine.medscape.com]
Prevalence, pathophysiology, and treatment of rhegmatogenous retinal detachment in treated cytomegalovirus retinitis. Am J Ophthalmol 1987; 103:527-36. 61. Holland GN, Sakamoto MJ, Hardy D, Sidikaro Y, Kreiger AE, Frenkel LM. [hivinsite.ucsf.edu]
Prevention
Encyclopedia) RPR test (Medical Encyclopedia) Syphilis (Centers for Disease Control and Prevention) Syphilis - primary (Medical Encyclopedia) Syphilis and MSM (Men Who Have Sex with Men) (Centers for Disease Control and Prevention) VDRL test (Medical [icdlist.com]
Workowski KA, Berman S, Centers for Disease Control and Prevention (CDC). MMWR Recomm Rep. 2010 ; 59 ( RR-12 ): 1 - 110. Congenital Syphilis—United States, 2003-2008. Centers for Disease Control and Prevention (CDC). [pedsinreview.aappublications.org]
The 2010 Centers for Disease Control and Prevention guidelines now recommend that ocular syphilis be treated as neurosyphilis regardless of the lumbar puncture results. There is a paucity of emergency medicine literature on ocular syphilis. [westjem.com]
According to statistics from the 2008 National STD Prevention Conference ( http://www.cdc.gov/stdconference/ 2008/media/ release-12march 2008.htm ), 2007 marked the seventh consecutive year that the rate of syphilis rose in the United States—a year when [reviewofophthalmology.com]
Syphilis and human immunodeficiency virus: prevention and politics. Arch Neurol. 2004;61(10):1505-1508. Chesson HW, Pinkerton SD, Irwin KL, Rein D, Kassler WJ. [retinalphysician.com]