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Syphilitic Heart Disease

Heart Disease due to Syphilis


Presentation

  • Presents comprehensive coverage of valvular heart disease to provide you with a complete reference and one-stop shop for this specialty in cardiac medicine.[books.google.com]
  • Snapshot A 40-year-old woman presents to her primary care physician for a wellness exam. She currently does not have any acute concerns and reports to feeling well.[medbullets.com]
  • Benefit from matchless Netter illustrations that offer precision, clarity, detail and realism as they provide a visual approach to the clinical presentation and care of the patient.[books.google.de]
  • Past history of rheumatic fever may be present 3. Other valves may be affected 4. Usually there is no diastolic thrill 6. Murmur is of blowing character 7. It is best heard on 3 rd left intercostals space 8. Peripheral signs of AR are present.[notes.medicosnotes.com]
  • So common was syphilis in days gone by, all physicians were attuned to its myriad clinical presentations.[bjcardio.co.uk]
Physician
  • Snapshot A 40-year-old woman presents to her primary care physician for a wellness exam. She currently does not have any acute concerns and reports to feeling well.[medbullets.com]
  • […] logo-32 logo-40 logo-60 New England Journal of Medicine NEJM Group Follow Us Facebook Twitter Instagram YouTube LinkedIn Blog Prepare to become a physician, build your knowledge, lead a health care organization, and advance your career with NEJM Group[nejm.org]
  • Grasp current clinical concepts regarding development, pediatrics, and adult medicine captured in classic Netter illustrations, as well as new illustrations created by artist-physician Carlos Machado, MD, and others working in the Netter style.[books.google.de]
  • Beyond Home Remedies: When To Call Your Doctor Contact your physician if you or your sexual partner develops signs of syphilis. Also contact your physician if you have had sexual contact with someone you suspect may have syphilis.[healthcommunities.com]
  • It is this phase that confounds physicians in its resemblance to several other types of diseases, including cancer, autoimmune disorders, vascular disease processes, or perhaps another infectious bug altogether.[blogs.discovermagazine.com]
Prostitute
  • Eager to partake in the business’s offerings, Capone sampled many of the prostitutes working there and, soon enough, contracted syphilis. Capone was too ashamed to seek out medical attention for his “venereal disease.”[pbs.org]
  • It was a frank and unsettling depiction of the taboos of that time, of sex and sexually transmitted diseases, of infidelity and prostitution.” Pyromania![blogs.discovermagazine.com]
  • Sex Transm Dis 23: 51, 1996 211 Centers for Disease Control and Prevention: Relationship of syphilis to drug use and prostitution—Connecticut.[glowm.com]
Prostitute
  • Eager to partake in the business’s offerings, Capone sampled many of the prostitutes working there and, soon enough, contracted syphilis. Capone was too ashamed to seek out medical attention for his “venereal disease.”[pbs.org]
  • It was a frank and unsettling depiction of the taboos of that time, of sex and sexually transmitted diseases, of infidelity and prostitution.” Pyromania![blogs.discovermagazine.com]
  • Sex Transm Dis 23: 51, 1996 211 Centers for Disease Control and Prevention: Relationship of syphilis to drug use and prostitution—Connecticut.[glowm.com]
Regurgitation
  • Features new chapters—Genetic, molecular and cellular mechanisms of valvular disease; Bicuspid aortic valve disease; and Ischemic mitral regurgitation—for the latest in cutting-edge research and clinical data.[books.google.com]
  • […] becomes impaired this leads to ischemic injury to the aortic media Pathogenesis believed to be caused by a vasculitis (obliterative endarteritis) of the vasa vasorum, which in turn, weakens the aortic root wall, leading to aortic dilation aortic valve regurgitation[medbullets.com]
  • In certain cases, however, an acute process may result in clinically abrupt expression of regurgitation. The pathophysiology and clinical presentation in acute valve regurgitation is different from that of chronic regurgitation.[karger.com]
  • Among patients with untreated syphilis, aortitis occurs in up to 70%–80%, and the clinically apparent manifestations of aortic regurgitation, coronary ostial stenosis and aortic aneurysms are seen in 10%–15%. 2 Although aortic regurgitation is rarely[mja.com.au]
  • The simultaneous presence of aortic regurgitation or significant coronary disease should be surgically treated at the same time.[humpath.com]
Hematochezia
  • Haug Browse recently published Learning/CME Learning/CME View all learning/CME CME Partial Oral versus Intravenous Antibiotic Treatment of Endocarditis Case 4-2019: An 18-Year-Old Man with Abdominal Pain and Hematochezia Bridging the Gap Challenge Yourself[nejm.org]
Diastolic Murmur
  • murmur Characteristic loud "tambour like" (booming and ringing quality like a drum) second sound is the most significant sign of syphilitic aortitis Complications Aortic aneurysm, aortic regurgitation and coronary ostia stenosis Laboratory Non treponemal[pathologyoutlines.com]
  • He also had a diastolic murmur that was discovered approximately 20 years ago during an insurance examination. The man was diagnosed with syphilis at age 19 and later treated with penicillin at age 30 when the drug became available.[mdmag.com]
Excitement
  • This classic Netter reference has been updated to mirror the many exciting advances in cardiovascular medicine and imaging – offering unparalleled insights into anatomy, physiology, and clinical conditions.[books.google.de]
  • This is considered to be the result of over-excitement of those with sub-clinical but advanced CHD who were watching the television on that day.[drdavidgrimes.com]
Neurologic Manifestation
  • Manifestations of HIV 910 Chapter 77 Gastrointestinal Manifestations of HIV Infection and AIDS 927 Chapter 78 Renal Manifestations of HIV Infection and AIDS 951 Chapter 79 HIV and Endocrine Manifestations 960 Chapter 80 AIDS Associated Malignancies and[books.google.com]
Sexual Dysfunction
  • Dysfunction 1203 Chapter 104 Womens Sexual Dysfunction 1210 Chapter 105 Sexuality Education for Young People 1221 A CultureBound Sex Related Disorder in Indian Subcontinent 1225 Chapter 107 Clinical Services for Sexually Transmitted Infections and HIV[books.google.com]

Treatment

  • […] of HIV in Industrialized and Middle Income CountriesŠAdults Adolescents and Pediatric 1310 Chapter 115 Guidelines for the Treatment of HIV and AIDS in ResourceLimited Countries 1328 Chapter 116 Guidelines for Prevention of Perinatal HIV Infection 1345[books.google.com]
  • Haug Browse recently published Learning/CME Learning/CME View all learning/CME CME Partial Oral versus Intravenous Antibiotic Treatment of Endocarditis Case 4-2019: An 18-Year-Old Man with Abdominal Pain and Hematochezia Bridging the Gap Challenge Yourself[nejm.org]
  • Treatment of Syphilis FIGURE 1. Recommended approach to the treatment of syphilis.[aafp.org]

Prognosis

  • […] depends on age, sex, occupation, stage of infection, site and extent of lesion, nature of lesion (progressive or stationary), response to treatment, cardiac efficiency, presence of complications The prognosis is better in patients with uncomplicated[pathologyoutlines.com]
  • Treatment and prognosis High-dose antibiotics and resection of enlarging aneurysm. History and etymology The term "lues" is an old name for syphilis, derived from Latin lues for "filth".[radiopaedia.org]
  • Presence of congestive heart failure affects the prognosis adversely. [6] Symptoms of aortic aneurysm Inflammation of the aortic wall leads to aortitis which later progresses to obliterative endarteritis of the vasa vasorum.[explainmedicine.com]
  • What is the prognosis? Patients with infectious syphilis should abstain from sexual activity until rendered noninfectious by antibiotic therapy. Talk openly with your partner about STDs, HIV, and hepatitis B infection, and the use of contraception.[healthcentral.com]
  • Syphilis Prognosis Primary, secondary, and early latent syphilis can be treated successfully with antibiotics. Late latency (more than 1 year after the secondary stage) is difficult to treat.[healthcommunities.com]

Etiology

  • ), cardiovascular; syphilitic (manifestation), disease (or disorder); heart, syphilitic (etiology), disease (or disorder); heart, syphilitic (manifestation), syphilis; cardiovascular (etiology), syphilis; cardiovascular (manifestation), Cardiovascular[fpnotebook.com]
  • Table 2 Mitral valve and aortic valve disease Table 3 Etiology of tricuspid and pulmonic valve disease Multivalvular Abnormalities and Current Common Etiologies We have presented many different etiologies of VHD.[karger.com]
  • Body leanness and hypertension are additional etiological factors for senile calcific aortic stenosis. Severe calcification of a congenital bicuspid aortic valve continues to be an important cause of aortic stenosis in the elderly.[journals.lww.com]
  • The rarity of this a etiology makes the diagnosis difficult, mainly because syphilis testing is not routinely used.[humpath.com]
  • Even in the urbanized region of Soweto where there is a high prevalence of vascular risk factors, non-ischemic etiologies are still the dominant cause of heart failure [8], [9].[journals.plos.org]

Epidemiology

  • Recent epidemiologic reports show an increase in reported cases related to the HIV infection. The rarity of this a etiology makes the diagnosis difficult, mainly because syphilis testing is not routinely used.[humpath.com]
  • The sexually transmitted bug that sullied Christopher Columbus’ journey either to the New World or his return back to the Old – we’re still debating this grand chicken-or-egg epidemiological mystery – has deranged the minds of dictators and kings, was[blogs.discovermagazine.com]
  • When good quality epidemiological studies were undertaken it was clear that those most at risk from early death from CHD (and almost all other causes of death) were the long-term unemployed.[drdavidgrimes.com]
  • Recent epidemiologic studies in adults suggested that the prevalence of VHD increases from 8 ].[karger.com]
  • Epidemiology Syphilis is primarily sustained in the population through sexual contact with infected persons.[clinicaladvisor.com]
Sex distribution
Age distribution

Pathophysiology

  • Definition / general Due to spirochete, Treponema pallidum Rare in developed and developing countries Male:female is 2:1 to 4:1 Affects aortic valve and ascending aorta Pathophysiology Treponema pallida reach cardiovascular system a short time after initial[pathologyoutlines.com]
  • VHD Etiology The major pathophysiologic entities associated with VHD are shown in table 1.[karger.com]

Prevention

  • Special attention is given to the prevention and treatment of these diseases found in developing countries as well as the latest findings about new antimicrobial agents, gram-negative infections and their management, and recommendations for immunization[books.google.com]
  • Encyclopedia) RPR test (Medical Encyclopedia) Syphilis (Centers for Disease Control and Prevention) Syphilis - primary (Medical Encyclopedia) Syphilis and MSM (Men Who Have Sex with Men) (Centers for Disease Control and Prevention) VDRL test (Medical[icdlist.com]
  • Centers for Disease Control and Prevention. Syphilis Fact Sheet. Available online at . Accessed June 2009. Centers for Disease Control and Prevention. STD surveillance, 2007. Available online at . Accessed August 2009. U.S.[labtestsonline.org]
  • Prevention Preventive measures to decrease the risk of syphilis, include: abstaining from sex long-term mutual monogamy with an uninfected partner condom use, although these protect only against genital sores and not those on the body.[medicalnewstoday.com]

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