Presentation
Presentation of latent syphilis Positive serology in a patient without symptoms or signs of disease is the most common presentation of syphilis in Australia today. Usually divided into early and late latent. [ww2.health.wa.gov.au]
Although infrequently seen, spirochetes are present in the necrotic centers of gummas. [histopathology-india.net]
These are not mutually exclusive; hence, they can all be present together. However, some forms may be more dominant than the other. [dovemed.com]
Hypercellular marrow was identified on bone marrow biopsy; lymphoid aggregates and lymphogranulomas were also present. [medicalxpress.com]
Lymphocytes are present in the outer layer. Often occuring in multiple subcutaneous locations and articular nocules in rheumatoid arthritis. [wikilectures.eu]
Hematological
- Easy Bruising
Cirrhosis can lead to Easy bruising or bleeding, or nosebleeds Swelling of the abdomen or legs Extra sensitivity to medicines High blood pressure in the vein entering the liver Enlarged veins called varices in the esophagus and stomach. [fpnotebook.com]
Weight Loss Jaundice Itching Nausea and sickness Easy bruising and nosebleeds Enlargement of breasts in men – this is due to a build up of female hormones which the liver would normally destroy. In the later stages more serious symptoms may occur. [homehealth-uk.com]
Jaundice Circulatory changes: spider telangiectasia, palmer erythema, cyanosis Endocrine changes: loss of libido, hair loss Male: gynecomastia, testicular atrophy, impotency Female: breast atrophy, irregular menses, amenorrhoea Hemorrhagic tendency: easy [homeobook.com]
Easy bruising. Poor concentration and memory. Bleeding oesophageal varices. Spontaneous bacterial peritonitis. Signs [ 3 ] Physical signs are variable and depend upon the extent of disease. Cutaneous features of cirrhosis include: Jaundice. [patient.info]
bruising; extreme skin dryness; intense skin itching; and spider angiomas (a central, raised, red dot about the size of a pin head from which small blood vessels radiate). [lifeextensionvitamins.com]
Liver, Gall & Pancreas
- Jaundice
Jaundice may complicate any stage of cirrhosis. [ordabok.net]
—Perhaps the most characteristic symptom is the rapidity with which jaundice appears, and frequent attacks of hepatic colic. If due to gall-stones, and their passage is affected, the jaundice disappears. [henriettes-herb.com]
Clinical manifestations of loss of appetite, weight loss, abdominal pain, diarrhea, gum bleeding, epistaxis, fever, jaundice, spleen, abdominal varicose veins, peritoneal effusion. basic knowledge Medicare disease: No Prevalence: 5% Susceptible people [healthfrom.com]
Jaundice, edema, and great abdominal swelling are common in all. [seslisozluk.net]
Coma, jaundice in: 3 marks : Chel 4. Liver with brain complications: Crot-h, phos, pyro, Tub. [homeobook.com]
- Hepatomegaly
Symptom Congenital syphilitic cirrhosis Symptoms Common symptoms Malignant jaundice hepatomegaly liver follicular atrophy liver failure splenomegaly nausea skin itching abortion hepatic stellate cell hyperplasia Should be based on clinical features, liver [healthfrom.com]
SYCOTIC Chronic Hepatitis Hepatomegaly b. TUBERCULAR Oesophageal varices c. [homeobook.com]
On examination he had gross ascites and hepatomegaly. A week after admission he had an episode of haematemesis and gastroscopy showed that he was bleeding from oesophageal varices. [pathologylearningcentre.uct.ac.za]
) cystic disease of liver (congenital) ( Q44.6 ) hepatic vein thrombosis ( I82.0 ) hepatomegaly NOS ( R16.0 ) portal vein thrombosis ( I81 ) toxic liver disease ( K71.- ) K76.0 Fatty (change of) liver, not elsewhere classified K76.1 Chronic passive [apps.who.int]
Other signs include: Hepatomegaly and a nodular liver. Oedema. Gynaecomastia and male hair loss pattern. Hypogonadism/testicular atrophy/amenorrhoea (due to the direct toxic effect of alcohol in alcoholic cirrhosis or iron in haemochromatosis). [patient.info]
Workup
Ultrasound
- Enlargement of the Spleen
As cirrhosis progresses, it may cause: Jaundice —yellowing of the skin and whites of the eyes Dark urine Water retention and swelling in the legs and abdomen Enlarged liver or spleen Loss of body hair Bleeding and bruising Vomiting blood Neurological [uvahealth.com]
Some engorgement and enlargement of the spleen is common; oedematous swelling of the wall of the stomach and bowel, with consequent impairment of digeetion and movement, is another result: dilatation of the veins and enlargement of the channels by which [smokh.org]
The spleen becomes greatly enlarged, owing to enormous congestion. [henriettes-herb.com]
Biopsy
- Liver Biopsy
Coverage also includes a timely discussion on liver transplantation...and speculations on the future of the liver biopsy. A bound-in CD-ROM contains over 500 full-color images . [books.google.de]
Changes consistent with liver cirrhosis and splenomegaly were identified on computed tomography; liver biopsy showed chronic portal tract inflammation. Diffuse heterogeneous uptake in the bone marrow was seen on positron emission tomography. [medicalxpress.com]
Six of the patients had a liver biopsy before treatment and the main findings were mononuclear cell infiltration around the central veins and portal tracts. [link.springer.com]
The architecture of the entire liver and its vasculature is disrupted. This fragment of cirrhotic liver was sampled by liver biopsy. Fibrous septae (staining red) surround regenerative nodules of liver cells. [pathologylearningcentre.uct.ac.za]
Diagnosis of cirrhosis can be suggested by physical examination and blood tests, and can be confirmed by liver biopsy in some patients. [ordabok.net]
Treatment
Treatment Treatment of congenital syphilitic cirrhosis: treatment Department of Gastroenterology Surgery Internal Medicine Treatment: drug treatment supportive treatment Treatment cycle: long-term medication Cure rate: 75% Commonly used drugs: twenty [healthfrom.com]
Treatment of external genital warts There is no cure or treatment that can eradicate HPV infection, so the only treatment is to remove the lesions caused by the virus. [medicinenet.com]
Treatment: Antibiotics can cure chlamydia. [stdcheck.com]
However, in all cases after treatment for syphilis, elevated liver enzyme levels returned to normal, usually within about four months after treatment. [catie.ca]
Prognosis
Prognosis This depends on the underlying cause and on the success of the treatment of the underlying cause. Prognosis is discussed in the separate articles for the conditions that can lead to cirrhosis. [patient.info]
The Cause and Prognosis of Ascites Due to Alcoholic Cirrhosis of the Liver, to Perihepatitis, and to Chronic Peritonitis. Guy’s Hosp. Rep., 49:1–42, 1892. Google Scholar 8. Bristow, J. [link.springer.com]
Prognosis and life expectancy in chronic liver disease. Dig Dis Sci. 1995;40:1805-15. Figures Figure 1. Indications for Liver Transplantation Evaluation This table shows the major indications for liver transplantation in adults. [hepatitisc.uw.edu]
Prognosis .—This is generally unfavorable. [henriettes-herb.com]
[…] bacteria) Excessive craving for drugs and alcohol, may lead to unsafe practices, such as ‘sex for drugs’ If you are frequently sexually active with multiple partners; then regular screening for sexually transmitted diseases is essential What is the Prognosis [dovemed.com]
Etiology
Code First Code First Help Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10data.com]
Etiology Congenital syphilis cirrhosis Etiology: The pathological changes of this type of hepatitis are like hepatitis A, there are hepatocellular balloon lesions, point or focal necrosis and infiltration of inflammatory cells in the portal area, mainly [healthfrom.com]
Seite 243 - To avoid prolixity we shall only mention the most important etiological causes. The two principal kinds of pneumonia are the primary and the secondary form. [books.google.de]
Article 15 Downloads 16 Citations Summary In our study, alcohol was the most frequently encountered contributing etiologic factor. Fifty-one per cent of the patients gave a history of the consumption of alcoholic beverages in excessive amounts. [link.springer.com]
As in the majority of the cases syphilis seems to be the etiological factor, a trial of antisyphilitic treatment would appear rational, although the results are limited because the process has, as a rule, run its course when the disease comes under observation [gluedideas.com]
Epidemiology
Epidemiology Treponema pallidum, the causative agent of syphilis, belongs to the family Spirochaetaceae and is a unicellular, spiral organism that cannot be cultivated in vitro. [pedsinreview.aappublications.org]
Annals of Epidemiology. 2009 Jun;19(6):423-31. Leber A, MacPherson P, Lee BC. Epidemiology of infectious syphilis in Ottawa. Recurring themes revisited. Canadian Journal of Public Health. 2008 Sep-Oct;99(5):401-5. Peterman TA, Furness BW. [catie.ca]
Aetiology and local epidemiology The most important causes of both cirrhosis and HCC are alcohol and chronic viral hepatitis (B & C). [pathologylearningcentre.uct.ac.za]
[…] cirrhosis Symptoms Common symptoms Malignant jaundice hepatomegaly liver follicular atrophy liver failure splenomegaly nausea skin itching abortion hepatic stellate cell hyperplasia Should be based on clinical features, liver function tests, reference to epidemiological [healthfrom.com]
Epidemiology It is difficult to estimate the exact prevalence of cirrhosis, as previously undiagnosed cirrhosis is often found at post-mortem. [patient.info]
Prevention
Encyclopedia) RPR test (Medical Encyclopedia) Syphilis (Centers for Disease Control and Prevention) Syphilis - primary (Medical Encyclopedia) Syphilis and MSM (Men Who Have Sex with Men) (Centers for Disease Control and Prevention) VDRL test (Medical [icdlist.com]
Prevention Congenital syphilis cirrhosis prevention The disease caused by congenital syphilis, no effective preventive measures, should actively respond to "eugenics" call to improve the quality of the population. [healthfrom.com]
Aside from the prevention methods described above for these two most common links, research is also proceeding on various other ways of preventing cirrhosis, although the research to date remains purely experimental. [hepatitiscentral.com]
How can hepatitis B infection be prevented? A highly effective vaccine that prevents hepatitis B is currently available. [medicinenet.com]
Regular exercise should be encouraged and is important to prevent muscle wasting. [patient.info]