Cardiac manifestations are similar in the 2 groups, with pericarditis accounting for the majority of cardiac lupus at presentation. There are no reports to our knowledge of coronary arteritis as a presenting feature of pSLE. [ncbi.nlm.nih.gov]

Note : Hematologic workup of SLE include a complete blood count looking for leukopenia, lymphopenia, thrombocytopenia, and anemia. [lecturio.com]

The workup includes iron studies, haemoglobin electrophoresis depending on the patients’ indices, and other markers of hemolysis (reticulocyte count, haptoglobin, lactate dehydrogenase (LDH)). [ncbi.nlm.nih.gov]

Treatment efficacy and safety parameters were monitored and recorded. [ncbi.nlm.nih.gov]

[…] logistic regression analysis showed that atypical manifestations at onset (P .018), renal involvement at onset or during follow up (P .024), and central nervous system disease involvement during follow up (P .021) were independent predictors of poor prognosis [ncbi.nlm.nih.gov]

Prognosis Excellent prognosis: Minimal mesangial lupus nephritis and mesangial proliferative lupus nephritis (ISN/RPS 2003 classes I and II) Good prognosis: Focal lupus nephritis (ISN/RPS 2003 class III) only a minority of patients develop progressive [slideshare.net]

Furthermore, the patient was also seropositive for both antiphospholipid and neuromyelitis optica antibodies, which can have implications on prognosis and treatment options. [guthyjacksonfoundation.org]

Moreover these findings may have special importance for prognosis and treatment of pediatric onset SLE and pediatric arthritis. [kidsgetarthritistoo.org]

Early disease onset raises the probability of genetic etiology and it is more severe than adult SLE. Herein an eight-year-old girl with pSLE from consanguineous parents is reported. [ncbi.nlm.nih.gov]

Etiology The current best estimate is that SLE affects between 5,000 and 10,000 children in the United States. [pedclerk.bsd.uchicago.edu]

There are several similarities as well as differences between pediatric and adult-onset lupus erythematosus (LE) in regard to etiology, clinical manifestations, complications and prognosis. [ijpd.in]

Introduction Chronic autoimmune disorder of unknown origin leads to accumulation of autoimmune complexes in joints, skin, kidneys, lungs, heart, blood vessels, and nervous system Genetic & epidemiology common in 15-25 year old African-American women multiple [orthobullets.com]

Systemic lupus erythematosus in northwestern Spain: A 20-year epidemiologic study. Medicine (Baltimore) 2011;90:350-8. 17. Hamijoyo L, Bernal C, Navarra S. [sjkdt.org]

There are many similarities and differences between pediatric and adult disease in regard to epidemiological, clinical and therapeutic aspects. [ijpd.in]

Methods: For the 2000-2011 period, data was collected from the database of the French Epidemiological Center of Medical Causes of Death (CepiDc, Inserm) corresponding to death certificates (DC) on which SLE was listed as an underlying or non-underlying [acrabstracts.org]

Epidemiology There is a strong female predilection in adults, with women affected 9-13 times more than males. In children, this ratio is reversed, and males are affected two to three times more often. [radiopaedia.org]

PURPOSE OF REVIEW: This review summarizes the recent advances in complement biology and the evolving understanding of these contributions to the pathophysiology and treatment of predominantly pediatric disease syndromes. [ncbi.nlm.nih.gov]

Cell-mediated autoimmune responses also play a pathophysiologic role. [emedicine.medscape.com]

Research in pediatric SLE is desperately needed and provides a unique opportunity to understand how developmental immunology and the hormonal changes associated with puberty affect the pathophysiology of SLE. [nature.com]

This will permit us to conclude whether adult SLE is driven by the same pathophysiology as pediatric SLE. INVESTIGATOR BIOGRAPHIES back to top Virginia Pascual, M.D. Dr. [dana.org]

The primary care of pediatric SLE patients that is focused on preventing or delaying SLE morbidities may help to restore, maintain, or improve the quality of life for these patients. [ncbi.nlm.nih.gov]

If they take corticosteroids, they should be eating foods low in salt to help prevent high blood pressure and low in sugar to help prevent diabetes and weight gain. [printo.it]